Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China.


AIM:To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. MATERIALS & METHODS:A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract infections. WUPyV was detected using real-time PCR and complete genome was sequenced for randomly selected positive nasopharyngeal aspirate. RESULTS:Altogether 122 (7.5%) of 1617 children found to be infected with WUPyV and 88 (72.1%) were coinfected with other viruses during 2012-2015. The phylogenetic analysis showed that 14 strains from our study formed two new clusters (Id and IIIc) within the Branch I and Branch III, respectively. CONCLUSION:WUPyV is persistently circulating in China. Surveillance on WUPyV infection in wider areas and long persistence is warranted.


Future Microbiol


Future microbiology


Zhu T,Lu QB,Zhang SY,Wo Y,Zhuang L,Zhang PH,Zhang XA,Wei W,Liu W




Has Abstract


2017-05-01 00:00:00










  • Septic patients in the intensive care unit present different nasal microbiotas.

    abstract:AIM:The primary objective of this study was to evaluate correlations among mortality, intensive care unit (ICU) length of stay and airway microbiotas in septic patients. MATERIALS & METHODS:A deep-sequencing analysis of the 16S rRNA gene V4 region was performed. RESULTS:The nasal microbiota in septic patients was dom...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Tan XL,Liu HY,Long J,Jiang Z,Luo Y,Zhao X,Cai S,Zhong X,Cen Z,Su J,Zhou H

    更新日期:2019-03-01 00:00:00

  • Pheromonicins: an ecologically sound family of bacteriocin-based antibiotics for use in the age of the microbiome.

    abstract::The time is ripe to usher in a new paradigm in infection control and to move beyond our sole reliance on broad-spectrum antibiotics whose use results in extensive collateral damage to our microbiome and, in so doing, exerts significant selective pressures for resistance to emerge. We propose to supplement the existing...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Qiu XQ,Roy SM,Riley MA

    更新日期:2015-01-01 00:00:00

  • Genetics of Coxiella burnetii: on the path of specialization.

    abstract::Coxiella burnetii is an extremely infectious, zoonotic agent that causes Q fever in humans. With the exception of New Zealand, the bacterium is distributed worldwide. Coxiella is classified as a select agent based on its past and potential use as a bioweapon and its threat to public health. Despite decades of research...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Minnick MF,Raghavan R

    更新日期:2011-11-01 00:00:00

  • Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead.

    abstract::Infections caused by pathogenic Rickettsia species continue to scourge human health across the globe. From the point of entry at the site of transmission by arthropod vectors, hematogenous dissemination of rickettsiae occurs to diverse host tissues leading to 'rickettsial vasculitis' as the salient feature of pathogen...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Narra HP,Sahni A,Walker DH,Sahni SK

    更新日期:2020-06-01 00:00:00

  • Attenuation of quorum sensing-mediated virulence of Acinetobacter baumannii by Glycyrrhiza glabra flavonoids.

    abstract:AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Bhargava N,Singh SP,Sharma A,Sharma P,Capalash N

    更新日期:2015-01-01 00:00:00

  • Methods for culturing anaerobes from human specimen.

    abstract::Anaerobes represent the dominating population in the human gut microbiota and play a key role in gut homeostasis. In addition, several anaerobes are now considered as probiotics and they remain essential to several processes in the field of biotechnology. With the implementation of MALDI-TOF MS in routine laboratories...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Guilhot E,Khelaifia S,La Scola B,Raoult D,Dubourg G

    更新日期:2018-03-01 00:00:00

  • Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.

    abstract::Resistance continues to emerge as a leading cause for antiretroviral treatment failure. Several mutations in HIV reverse transcriptase (RT) confer resistance to non-nucleoside inhibitors (NNRTIs), vital components of antiretroviral combination therapies. Since the majority of mutations are located in the NNRTI binding...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Frey KM

    更新日期:2015-01-01 00:00:00

  • Clinical and molecular epidemiology of Acinetobacter baumannii bloodstream infections in an endemic setting.

    abstract:AIM:The transmission dynamics of Acinetobacter baumannii in endemic settings, and the relation between microbial properties and patients' clinical outcomes, are yet obscure and hampered by insufficient metadata. METHODS & RESULTS:Of 20 consecutive patients with A. baumannii bloodstream infection that were thoroughly a...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Marchaim D,Levit D,Zigron R,Gordon M,Lazarovitch T,Carrico JA,Chalifa-Caspi V,Moran-Gilad J

    更新日期:2017-03-01 00:00:00

  • Effects of hyperbaric oxygen on Pseudomonas aeruginosa susceptibility to imipenem and macrophages.

    abstract:BACKGROUND:The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). MATERIALS & METHODS:The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen on bacterial counts of six is...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Lima FL,Joazeiro PP,Lancellotti M,de Hollanda LM,de Araújo Lima B,Linares E,Augusto O,Brocchi M,Giorgio S

    更新日期:2015-01-01 00:00:00

  • Role of catalase overproduction in drug resistance and virulence in Candida albicans.

    abstract:AIM:To investigate the role of Cat1 overproduction in Candida albicans. MATERIALS & METHODS:Strains overproducing the CAT1 gene were constructed. RESULTS:Cells overproducing CAT1 were found to be more resistant to some oxidants and mammalian phagocytic cells. They also showed reduced intracellular reactive oxygen spe...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Román E,Prieto D,Martin R,Correia I,Mesa Arango AC,Alonso-Monge R,Zaragoza O,Pla J

    更新日期:2016-10-01 00:00:00

  • Retapamulin: a semisynthetic pleuromutilin compound for topical treatment of skin infections in adults and children.

    abstract::Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...

    journal_title:Future microbiology

    pub_type: 临床试验,杂志文章


    authors: Jacobs MR

    更新日期:2007-12-01 00:00:00

  • Resistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection.

    abstract::Inhibitors that target the retroviral enzyme reverse transcriptase (RT) have played an indispensable role in the treatment and prevention of HIV-1 infection. They can be grouped into two distinct therapeutic groups, namely the nucleoside and nucleotide RT inhibitors (NRTIs), and the non-nucleoside RT inhibitors (NNRTI...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Sluis-Cremer N,Wainberg MA,Schinazi RF

    更新日期:2015-01-01 00:00:00

  • New perspectives in the management of Pseudomonas aeruginosa infections.

    abstract::Infections with Pseudomonas aeruginosa are a major health problem, especially for immune-compromised and cystic fibrosis patients, owing to the particular drug resistance of the microorganism. The aim of this review is to provide recent insights into strategies under investigation for prevention and therapy of these i...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Savoia D

    更新日期:2014-01-01 00:00:00

  • Emergence of two distinct subpopulations from Klebsiella pneumoniae grown in the stimulated microgravity environment.

    abstract:AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Wang H,Li W,Gu L,Gao X,Ni B,Deng H,Yang R,Han Y

    更新日期:2017-09-01 00:00:00

  • Potentially pathogenic amoeba-associated microorganisms in cooling towers and their control.

    abstract::Cooling towers provide a favorable environment for the proliferation of microorganisms. Cooling towers generate a biofilm and often aerosolize contaminated water, thereby increasing the risk of microorganism dissemination by human inhalation. This pathogen dissemination was first revealed by the epidemics of Legionnai...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Pagnier I,Merchat M,La Scola B

    更新日期:2009-06-01 00:00:00

  • Nanoscale exploration of microbial surfaces using the atomic force microscope.

    abstract::Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Dufrêne YF

    更新日期:2006-12-01 00:00:00

  • Interview with Professor Mark Wilcox.

    abstract::Mark Wilcox speaks to Georgia Patey, Commissioning Editor: Professor Mark Wilcox is a Consultant Microbiologist and Head of Microbiology at the Leeds Teaching Hospitals (Leeds, UK), the Professor of Medical Microbiology at the University of Leeds (Leeds, UK), and is the Lead on Clostridium difficile and the Head of th...

    journal_title:Future microbiology

    pub_type: 面试


    authors: Wilcox M

    更新日期:2016-08-01 00:00:00

  • Differentiation between Staphylococcus aureus and Staphylococcus epidermidis strains using Raman spectroscopy.

    abstract:AIM:Raman spectroscopy is an analytical method with a broad range of applications across multiple scientific fields. We report on a possibility to differentiate between two important Gram-positive species commonly found in clinical material - Staphylococcus aureus and Staphylococcus epidermidis - using this rapid nonin...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Rebrošová K,Šiler M,Samek O,Růžička F,Bernatová S,Ježek J,Zemánek P,Holá V

    更新日期:2017-08-01 00:00:00

  • Molecular phylogenetics and epidemiology of Candida albicans.

    abstract::Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundament...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Odds FC

    更新日期:2010-01-01 00:00:00

  • Manipulation of the bluetongue virus tubules for immunogen delivery.

    abstract::A multidisplay vaccine delivery system has been developed that is nonreplicating and has a protein-based particulate structure. The structure is composed of helical tubules comprising multiple copies of a single nonstructural (NS) protein 1 of bluetongue virus. The helical assemblies present the C terminus of the prot...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Murphy A,Roy P

    更新日期:2008-06-01 00:00:00

  • Comparative analysis between biofilm formation and gene expression in Staphylococcus epidermidis isolates.

    abstract:AIM:To understand the relationship between ica, aap and bhp gene expression and the implications in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates. MATERIAL & METHODS:Isolates were analyzed regarding their biofilm-forming capacity, biochemical matrix composition, biofilm spati...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Freitas AI,Lopes N,Oliveira F,Brás S,França Â,Vasconcelos C,Vilanova M,Cerca N

    更新日期:2018-03-01 00:00:00

  • Gut permeability, its interaction with gut microflora and effects on metabolic health are mediated by the lymphatics system, liver and bile acid.

    abstract::There is evidence to link obesity (and metabolic syndrome) with alterations in gut permeability and microbiota. The underlying mechanisms have been questioned and have prompted this review. We propose that the gut barrier function is a primary driver in maintaining metabolic health with poor health being linked to 'gu...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Tran CD,Grice DM,Wade B,Kerr CA,Bauer DC,Li D,Hannan GN

    更新日期:2015-01-01 00:00:00

  • Helicobacter pylori virulence factors in development of gastric carcinoma.

    abstract::Helicobacter pylori plays a vital role in the pathogenesis of gastric carcinoma. However, only a relatively small proportion of individuals infected with H. pylori develop gastric carcinoma. Differences in the incidence of gastric carcinoma among infected individuals can be explained, at least partly, by the different...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Wang MY,Liu XF,Gao XZ

    更新日期:2015-01-01 00:00:00

  • Tuberculosis drugs: new candidates and how to find more.

    abstract::The recent years have witnessed significant progress in the development of new drug candidates for the treatment of TB. While many of these are now in clinical trials, continued research is needed in order to sustain the drug discovery pipeline and meet the increasing needs of TB patients. These include shortening tre...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Sala C,Hartkoorn RC

    更新日期:2011-06-01 00:00:00

  • Better than a pound of cure: preventing the development of multidrug-resistant tuberculosis.

    abstract::Diagnostic and treatment delays contribute to increased death and disability among the 490,000 adults and children who develop multidrug-resistant (MDR) tuberculosis every year. Since the treatment of MDR tuberculosis is complex, costly and often toxic, tuberculosis control programs should prioritize strategies to pre...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Byrne AL,Fox GJ,Marais BJ

    更新日期:2018-04-01 00:00:00

  • γ-irradiation from radiotherapy improves the virulence potential of Candida tropicalis.

    abstract:AIM:To evaluate if radiation used in radiotherapy can cause changes in the virulence potential of Candida tropicalis ATCC 750. MATERIALS & METHODS:C. tropicalis was exposed in vitro to identical dose and scheme of irradiation would be used in patients with head and neck cancer. Some virulence parameters were analyzed ...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: da Silva EM,Kischkel B,Shinobu-Mesquita CS,Bonfim-Mendonça PS,Mansano ES,da Silva MA,Barbosa JF,Fiorini A,Hernandes L,Furlaneto MC,Svidzinski TI

    更新日期:2017-12-01 00:00:00

  • Protective host immune responses to Salmonella infection.

    abstract::Salmonella enterica serovars Typhi and Paratyphi are the causative agents of human typhoid fever. Current typhoid vaccines are ineffective and are not widely used in endemic areas. Greater understanding of host-pathogen interactions during Salmonella infection should facilitate the development of improved vaccines to ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Pham OH,McSorley SJ

    更新日期:2015-01-01 00:00:00

  • Inhibition of growth and gene expression in Staphylococcus aureus by anti-gyrA peptide nucleic acid.

    abstract::Aim: Multidrug-resistant Staphylococcus aureus isolates have become a serious concern in clinical microbiology. Antisense strategy, which specifically targets essential genes, could be helpful. Materials & methods:S. aureus cultures were treated with peptide conjugate-peptide nucleic acid (PPNA) specific for the gyrA ...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Tavakoli M,Hashemi A,Vaezjalali M,Mohammadzadeh M,Goudarzi H

    更新日期:2019-09-01 00:00:00

  • Promises and failures of gallium as an antibacterial agent.

    abstract::Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is exogenously supplied to living cells it can replace Fe(III) within target molecules, thereby perturbing bacterial metabolism. Ga(III)-induced metabolic distresses a...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Minandri F,Bonchi C,Frangipani E,Imperi F,Visca P

    更新日期:2014-01-01 00:00:00

  • SAMHD1: a novel antiviral factor in intrinsic immunity.

    abstract::Some intracellular/membranous factors exert intrinsic immunity against viral pathogens. Most recently, SAMHD1 has been shown to be one of these factors. SAMHD1 is a nucleus-localized protein, and mutations in the gene are associated with Aicardi-Goutières syndrome. As a triphosphohydrolase, it depletes the intracellul...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Chen Z,Zhang L,Ying S

    更新日期:2012-09-01 00:00:00