Abstract:
STUDY OBJECTIVE:To investigate the incidence and predictive factors of 30-day surgery-related morbidity and occult precancerous and cancerous conditions for women undergoing risk-reducing surgery. DESIGN:A prospective study (Canadian Task Force classification II-1). SETTING:A gynecologic oncology referral center. PATIENTS:Breast-related cancer antigen (BRCA) mutation carriers and BRCAX patients (those with a significant family history of breast and ovarian cancer). INTERVENTIONS:Minimally invasive risk-reduction surgery. MEASUREMENTS AND MAIN RESULTS:Overall, 85 women underwent risk-reducing surgery: 30 (35%) and 55 (65%) had hysterectomy plus bilateral salpingo-oophorectomy (BSO) and BSO alone, respectively. Overall, in 6 (7%) patients, the final pathology revealed unexpected cancer: 3 early-stage ovarian/fallopian tube cancers, 2 advanced-stage ovarian cancers (stage IIIA and IIIB), and 1 serous endometrial carcinoma. Additionally, 3 (3.6%) patients had incidental finding of serous tubal intraepithelial carcinoma. Four (4.7%) postoperative complications within 30 days from surgery were registered, including fever (n = 3) and postoperative ileus (n = 1); no severe (grade 3 or more) complications were observed. All complications were managed conservatively. The presence of occult cancer was the only factor predicting the development of postoperative complications (p = .02). CONCLUSION:Minimally invasive risk-reducing surgery is a safe and effective strategy to manage BRCA mutation carriers. Patients should benefit from an appropriate counseling about the high prevalence of undiagnosed cancers observed at the time of surgery.
journal_name
J Minim Invasive Gynecoljournal_title
Journal of minimally invasive gynecologyauthors
Bogani G,Tagliabue E,Signorelli M,Chiappa V,Carcangiu ML,Paolini B,Casarin J,Scaffa C,Gennaro M,Martinelli F,Borghi C,Ditto A,Lorusso D,Raspagliesi Fdoi
10.1016/j.jmig.2017.04.017subject
Has Abstractpub_date
2017-01-01 00:00:00pages
837-842issue
5eissn
1553-4650issn
1553-4669pii
S1553-4650(17)30283-2journal_volume
24pub_type
杂志文章abstract:STUDY OBJECTIVE:We sought to estimate the impact of sentinel nodes in gynecologic oncology on fellowship training and discuss potential solutions. DESIGN:Retrospective multi-institution cohort (Canadian Task Force classification II-2). SETTING:Three tertiary cancer referral cancer centers. PATIENTS:Patients with end...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.08.006
更新日期:2019-01-01 00:00:00
abstract:STUDY OBJECTIVE:To explore the feasibility and effectiveness of a modified posterior vaginal mesh suspension method in treating female rectocele with intractable constipation. DESIGN:Descriptive study (Canadian Task Force classification II-3). SETTING:The study was performed in the Study Center for Female Pelvic Dysf...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2012.06.004
更新日期:2012-11-01 00:00:00
abstract:STUDY OBJECTIVE:To describe the surgical technique and short-term outcomes for 26 cases of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) sacrocolpopexy for the treatment of pelvic organ prolapse (POP). DESIGN:Retrospective case series study (Canadian Task Force classification II-2). SETTING:Ac...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.08.009
更新日期:2019-01-01 00:00:00
abstract::Female reproductive tract anomalies are difficult to number in the general population but are often discovered in evaluations of menstrual complications or fertility disorders. Traditionally, assessment of the reproductive tract entailed hysterosalpingography to image the uterine cavity with the final diagnosis provid...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2013.10.014
更新日期:2014-05-01 00:00:00
abstract:STUDY OBJECTIVE:To present a modified technique for laparoscopic cornual resection for the surgical treatment of heterotopic istmocornual pregnancy. DESIGN:A step-by-step explanation of the surgery using video (Canadian Task Force Classification III-c). SETTING:Heterotopic pregnancy is the coexistence of pregnancy in...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2016.07.008
更新日期:2017-01-01 00:00:00
abstract::The primary goal of the clinical evaluation of abnormal uterine bleeding is to establish a specific diagnosis in the most efficient and least invasive manner possible. Hysteroscopy (HS) allows physicians to obtain directed biopsy in addition to direct visualization of the uterine cavity and lesions, but often requires...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2006.08.003
更新日期:2006-11-01 00:00:00
abstract::Adnexal masses are a common indication for surgery in the United States. This article reviews the clinical features that may suggest an underlying malignancy, including ultrasound and biomarkers. The decision regarding how to remove an adnexal mass involves consideration of several factors, including body habitus, int...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2016.11.010
更新日期:2017-02-01 00:00:00
abstract::At laparoscopic-assisted vaginal hysterectomy with a novel "paper roll" vaginal morcellation technique, large uteri (> or = 500 g) can be removed via the vagina with safety, speed, and ease. The technique provides protection for the bladder and rectum, and large uteri can be removed in 1 piece, allowing the pathologis...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2010.02.005
更新日期:2010-05-01 00:00:00
abstract::There is an ongoing debate regarding the benefits and drawbacks of the various routes of hysterectomy. A number of studies have examined overall quality of life outcomes as well as specific patient-reported outcomes including physical, psychosocial, and sexual functioning after hysterectomy. Existing studies have used...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.08.019
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To describe the surgical approaches and excisional techniques used in an extreme case of deep infiltrating endometriosis (DIE) affecting the lateral pelvic side wall. DESIGN:A technical video showing the excision of advanced lateral DIE. SETTING:An academic tertiary care hospital. INTERVENTIONS:A 32-year-o...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2019.06.019
更新日期:2020-02-01 00:00:00
abstract:STUDY OBJECTIVE:To describe the feasibility of performing Essure hysteroscopic sterilization immediately after NovaSure global endometrial ablation (GEA). DESIGN:Descriptive feasibility study (Canadian Task Force classification III). SETTING:Midwestern United States academic medical center. PATIENTS:Twenty-five wome...
journal_title:Journal of minimally invasive gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/j.jmig.2007.01.014
更新日期:2007-07-01 00:00:00
abstract::Hernia uterine inguinale is a rare condition often presenting within the first few years of life as an asymptomatic palpable mass in the inguinal/groin area. This type of hernia contains uterine tissue and may contain oviducts, ovaries, and rarely the bladder. We report a case of a woman with a history of pelvic pain,...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2010.06.008
更新日期:2010-11-01 00:00:00
abstract:STUDY OBJECTIVE:To show an original technique of laparoscopic lateral suspension (LLS) with a precut mesh in a difficult case of vaginal vault prolapse. DESIGN:Step-by-step descriptions of the technique using videos (educational video). SETTING:Vaginal vault prolapse affects up to 1% of patients who had a hysterectom...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2016.01.028
更新日期:2016-07-01 00:00:00
abstract:STUDY OBJECTIVE:We sought to estimate effectiveness of transdermal scopolamine to prevent postoperative nausea and vomiting after gynecologic laparoscopy. DESIGN:Patients were randomized to receive preoperative transdermal scopolamine or placebo. Main outcome measure was incidence of nausea during the first 24 hours p...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2007.08.616
更新日期:2008-01-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the feasibility of total laparoscopic hysterectomy (TLH) using the Hohl instrument in an initial cohort of patients. DESIGN:Retrospective cohort analysis (Canadian Task Force classification II-3). SETTING:Department of Obstetrics and Gynecology, Erlangen University Hospital, Erlangen, Germ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2005.04.006
更新日期:2005-09-01 00:00:00
abstract::We performed a literature review of reports comparing a levonorgestrel-releasing intrauterine device (LNG-IUD) with transcervical polyp resection (TCRP) as a treatment for heavy menstrual bleeding (HMB). Our second objective was to investigate the effectiveness of LNG-IUD and TCRP in reducing menstrual bleeding and th...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2015.06.016
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic accuracy of hysteroscopy compared with that of laparoscopic chromopertubation for the detection of fallopian tubal obstruction. DATA SOURCES:An electronic search from inception to March 31, 2020, was performed in Medline, Scopus, EMBASE, and the Cochrane Central Register of Controlle...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2020.11.013
更新日期:2020-11-25 00:00:00
abstract:STUDY OBJECTIVE:To identify the lengthiest step of total laparoscopic hysterectomy (TLH) in a teaching hospital and to determine which clinical factors affect the duration of this step. SETTING:The University of Louisville Hospital. DESIGN:Single institution retrospective case series. METHODS AND MAIN RESULTS:This i...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2015.04.020
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To demonstrate our technique for robot-assisted laparoscopic ectopic pregnancy excision and concomitant scar revision. DESIGN:We present a stepwise narrated demonstration of our primary laparoscopic technique. SETTING:Although cesarean scar pregnancy is rare, it leads to life-threatening complications and o...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.06.017
更新日期:2020-06-27 00:00:00
abstract:STUDY OBJECTIVE:To determine whether completion rates of salpingostomy for tubal ectopic pregnancy are compromised by initial medical management with methotrexate (MTX). DESIGN:Retrospective cohort study. SETTING:Single academic hospital system. PATIENTS:Patients requiring surgery for ectopic pregnancy between 2006 ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.09.003
更新日期:2020-09-07 00:00:00
abstract:STUDY OBJECTIVE:To estimate the clinical significance of pouch of Douglas (POD) obliteration in women undergoing laparoscopic excision of endometriosis. DESIGN:Prospective study (Canadian Task Force Classification II-2). SETTING:University-affiliated tertiary referral center for endometriosis. PATIENTS:A total of 45...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2011.01.011
更新日期:2011-05-01 00:00:00
abstract:STUDY OBJECTIVE:To review pregnancy outcomes after laparoscopic myomectomy with the use of barbed suture. DESIGN:Retrospective cohort study and follow-up survey. SETTING:Single, large academic medical center. PATIENTS:Patients who underwent laparoscopic myomectomy with the use of barbed suture for myometrial closure...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.02.005
更新日期:2020-01-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate the effects of hypoxia-inducible factor (HIF) inhibitors, flotation agents, barriers, and a surfactant on pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model. DESIGN:Prospective randomized trial (Canadian Task Force classification I). SETTING:Department of Obstetrics and G...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2007.04.002
更新日期:2007-09-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the impact of ultrasound-guided transvaginal ovarian needle drilling (TND) versus laparoscopic ovarian drilling (LOD) on ovarian reserve and pregnancy rate in patients with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS). DESIGN:A randomized clinical trial (Canadian Task F...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2018.01.036
更新日期:2018-01-01 00:00:00
abstract:STUDY OBJECTIVE:To demonstrate the proper use of vessel-sealing devices during vaginal hysterectomy. DESIGN:Educational video (Canadian Task Force classification level III). SETTING:University hospital. INTERVENTION:The video reviews the principles on the use of energy in minimally invasive surgery. We focus on how ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.04.018
更新日期:2019-02-01 00:00:00
abstract::Although endometrial cancer, the most common gynecologic malignancy, is most often diagnosed in postmenopausal women, it affects young women who wish to preserve fertility. The purpose of this article is to describe 2 cases of stage IA endometrial cancer managed conservatively by a combination of hysteroscopic surgery...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2014.08.782
更新日期:2015-01-01 00:00:00
abstract::A 33-year-old woman with a 2-year history of swelling and pain in her buttock and left thigh fluctuating with her menstrual cycle who was becoming progressively disabled was referred to the department of orthopedics. Magnetic resonance imaging (MRI) detected a left buttock lesion of 3 x 2 cm that was initially diagnos...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2008.09.619
更新日期:2009-01-01 00:00:00
abstract:STUDY OBJECTIVES:To study the surgical and functional outcomes of single-incision mesh surgery for treatment of advanced pelvic organ prolapse (POP). DESIGN:Case series (Canadian Task Force classification II-3). SETTING:University hospital. PATIENTS:Sixty-five patients who underwent surgery to treat symptomatic POP ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2014.07.002
更新日期:2015-01-01 00:00:00
abstract::Laparoscopic vessel sealing devices have revolutionized modern laparoscopy. These devices fall into 2 major categories: advanced bipolar and ultrasonic instruments. The range of tissue effects available with these technologies is more limited than with conventional monopolar electrosurgery; however, both advanced bipo...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2013.02.012
更新日期:2013-05-01 00:00:00
abstract:STUDY OBJECTIVE:To demonstrate the feasibility of sentinel lymph node (SLN) biopsy using a laparoendoscopic single-site (LESS) approach in endometrial cancer (EC). DESIGN:A step-by-step video demonstration of the surgical procedure (Canadian Task Force Classification III). SETTING:The satisfaction of patients who und...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2017.10.035
更新日期:2018-01-01 00:00:00