New approaches to combat Porphyromonas gingivalis biofilms.

abstract：:Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-well plates, without the requirement for any further manipulation. Design and R...

journal_title：Journal of oral microbiology

authors： Mira A,Buetas E,Rosier B,Mazurel D,Villanueva-Castellote Á,Llena C,Ferrer MD

更新日期：2019-05-06 00:00:00

abstract：:For decades, Aggregatibacter actinomycetemcomitans has been associated with aggressive forms of periodontitis in adolescents. In the middle of the 1990s, a specific JP2 clone of A. actinomycetemcomitans, belonging to the cluster of serotype b strains of A. actinomycetemcomitans and having a number of other characteris...

journal_title：Journal of oral microbiology

authors： Haubek D,Johansson A

更新日期：2014-08-14 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis inhibits oral epithelial wound healing in vitro more strongly than other oral bacteria, but it is unknown why P. gingivalis is such a potent inhibitor of wound healing. OBJECTIVE:Therefore, the aim of this study was to investigate the influence of major virulence factors of P. gingi...

journal_title：Journal of oral microbiology

authors： Laheij AM,van Loveren C,Deng D,de Soet JJ

更新日期：2015-07-02 00:00:00

abstract：:Objective: Provide evidence of HPV, C. trachomatis, and HSV infection in the oral cavity from patients with different types of stomatological lesions. Materials and Methods: Oral swabs samples were collected from a total of 318 patients. The infectious agents were analyzed using the PCR technique. HPV genotyping and H...

journal_title：Journal of oral microbiology

authors： Mosmann JP,Talavera AD,Criscuolo MI,Venezuela RF,Kiguen AX,Panico R,Ferreyra De Prato R,López De Blanc SA,Ré V,Cuffini CG

更新日期：2019-06-25 00:00:00

abstract：:Aggregatibacter actinomycetemcomitans and Aggregatibacter aphrophilus belong to the HACEK group of fastidious Gram-negative organisms, a recognized cause of infective endocarditis. A. actinomycetemcomitans is also implicated in aggressive forms of periodontitis. We demonstrated that A. aphrophilus strains, as A. actin...

journal_title：Journal of oral microbiology

authors： Lindholm M,Min Aung K,Nyunt Wai S,Oscarsson J

更新日期：2018-10-26 00:00:00

abstract：:Objective: Microvascular dysfunction is a feature of periodontal disease. P. gingivalis, one of the most common oral bacteria present in gingival tissue biofilms, has also been identified in the gingival capillaries of patients with chronic periodontitis. We sought to determine the effect of P. gingivalis W83 infectio...

journal_title：Journal of oral microbiology

authors： Reyes L,Getachew H,Dunn WA,Progulske-Fox A

更新日期：2020-03-26 00:00:00

abstract：:Antibiotic resistance is an ever-growing problem faced by all major sectors of health care, including dentistry. Recurrent infections related to multidrug-resistant bacteria such as methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, and vancomycin-resistant enterococci (VRE) in hospi...

journal_title：Journal of oral microbiology

authors： Khalifa L,Shlezinger M,Beyth S,Houri-Haddad Y,Coppenhagen-Glazer S,Beyth N,Hazan R

更新日期：2016-09-16 00:00:00

abstract：:The protected niche of deep-caries lesions is a distinctive ecosystem. We assessed the Candida biome and its cariogenic traits from dentin samples of 50 children with severe-early childhood caries (S-ECC). Asymptomatic, primary molars belonging to International Caries Detection and Assessment-ICDAS caries-code 5 and 6...

journal_title：Journal of oral microbiology

authors： Fakhruddin KS,Perera Samaranayake L,Egusa H,Chi Ngo H,Panduwawala C,Venkatachalam T,Kumarappan A,Pesee S

更新日期：2020-02-05 00:00:00

abstract：:Objectives: To investigate effects of nicotine on biofilm formation of Streptococcus mutans isolates from oral washes of smoker and non-smoker human subjects. Materials and methods: This study was conducted using 60 S. mutans isolates with three S. mutans isolates collected from oral washes of ten smoking subjects and...

journal_title：Journal of oral microbiology

authors： El-Ezmerli NF,Gregory RL

更新日期：2019-09-13 00:00:00

abstract：Backgroung:Roseolovirus latency and persistence in salivary glands that are frequently reactivated after renal transplantation to cause infection have been reported. However, limited information is available on the persistence and excretion of HHV-6 and HHV-7 during and after transplant. Methods:32 renal transplant re...

journal_title：Journal of oral microbiology

authors： Raposo JV,Sarmento DJS,Pinto RBDS,Lopes AO,Gallottini M,Tozetto-Mendoza TR,Braz-Silva PH,de Paula VS

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND AND OBJECTIVE:pH in dental biofilms is of central importance for the development of caries. We used the ratiometric pH-sensitive dye C-SNARF-4 in combination with digital image analysis to monitor extracellular pH in dental biofilms grown in situ with and without sucrose supply. DESIGN:Dental biofilms (48 h...

journal_title：Journal of oral microbiology

authors： Dige I,Baelum V,Nyvad B,Schlafer S

更新日期：2016-02-15 00:00:00

abstract：:Sealed cariogenic bacteria are deprived from dietary carbohydrate, but could be provided with nutrients by pulpal fluids, with adaptive strain-specific activities being possible. We investigated survival and metabolic activity of the cariogenic bacteria Streptococcus sobrinus, Actinomyces naeslundii and Lactobacillus ...

journal_title：Journal of oral microbiology

authors： Ganas P,Schwendicke F

更新日期：2019-04-22 00:00:00

abstract：:The mouth supports a diverse microbiota which provides major benefits to the host. On occasions, this symbiotic relationship breaks down (dysbiosis), and disease can be a consequence. We argue that progress in the control of oral diseases will depend on a paradigm shift away from approaches that have proved successful...

journal_title：Journal of oral microbiology

authors： Marsh PD,Head DA,Devine DA

更新日期：2014-11-27 00:00:00

abstract：:This study investigated if chronic obstructive pulmonary disease (COPD) is correlated with periodontitis via periodontal microbiota and if certain bacteria affect periodontitis as well as COPD. Moreover, the study investigated whether suffering from COPD is associated with a decrease in the richness and diversity of p...

journal_title：Journal of oral microbiology

authors： Wu X,Chen J,Xu M,Zhu D,Wang X,Chen Y,Wu J,Cui C,Zhang W,Yu L

更新日期：2017-06-12 00:00:00

abstract：:The value of saliva as a diagnostic tool can be increased by taxonomic and functional analyses of the microbiota as recently demonstrated. In this proof-of-principle study, we compare two collection methods (Salivette® (SV) and paraffin gum (PG)) for stimulated saliva from five healthy participants and present a workf...

journal_title：Journal of oral microbiology

authors： Rabe A,Gesell Salazar M,Fuchs S,Kocher T,Völker U

更新日期：2018-01-24 00:00:00

abstract：BACKGROUND:Direct microscopy, anaerobic culture and DNA-DNA hybridization have previously demonstrated an association between microorganisms and osteoradionecrosis (ORN). The purpose of our study was to use culture independent molecular techniques to detect bacteria in necrotic bone lesions of the mandible after radiat...

journal_title：Journal of oral microbiology

authors： Aas JA,Reime L,Pedersen K,Eribe ER,Abesha-Belay E,Støre G,Olsen I

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:Identifying the microbial species in caries lesions is instrumental to determine the etiology of dental caries. However, a significant proportion of bacteria in carious lesions have not been cultured, and the use of molecular methods has been limited to DNA-based approaches, which detect both active and inac...

journal_title：Journal of oral microbiology

authors： Simón-Soro A,Guillen-Navarro M,Mira A

更新日期：2014-10-24 00:00:00

abstract：:In recent times the concept of infectious agents playing a role in cardiovascular disease has attracted much attention. Chronic oral disease such as periodontitis, provides a plausible route for entry of bacteria to the circulation. Upon entry to the circulation, the oral bacteria interact with platelets. It has been ...

journal_title：Journal of oral microbiology

authors： Kerrigan SW,Cox D

更新日期：2009-08-26 00:00:00

abstract：BACKGROUND:Behçet's syndrome (BS) is a multisystem immune-related disease of unknown etiology. Recurrent aphthous stomatitis (RAS) is characterized by the presence of idiopathic oral ulceration without extraoral manifestation. The interplay between the oral microbial communities and the immune response could play an im...

journal_title：Journal of oral microbiology

authors： Seoudi N,Bergmeier LA,Drobniewski F,Paster B,Fortune F

更新日期：2015-06-01 00:00:00

abstract：:Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease. The gingipains function as proteinases and transpeptidases utilising small peptides such as glyc...

journal_title：Journal of oral microbiology

authors： Seers CA,Mahmud ASM,Huq NL,Cross KJ,Reynolds EC

更新日期：2020-12-09 00:00:00

abstract：:In terms of the pathogenesis of cardiovascular disease (CVD) the focus has traditionally been on dyslipidemia. Over the decades our understanding of the pathogenesis of CVD has increased, and infections, including those caused by oral bacteria, are more likely involved in CVD progression than previously thought. While...

journal_title：Journal of oral microbiology

authors： Leishman SJ,Do HL,Ford PJ

更新日期：2010-12-21 00:00:00

abstract：AIM:Find the periodontal treatment that best maintained clinical results over time evaluated by changes in pocket depth (PD) and clinical attachment level (CAL). METHODS:229 patients with chronic periodontitis from USA (n=134) and Sweden (n=95) were randomly assigned to eight groups receiving (1) scaling+root planing ...

journal_title：Journal of oral microbiology

authors： Mdala I,Haffajee AD,Socransky SS,de Blasio BF,Thoresen M,Olsen I,Goodson JM

更新日期：2012-01-01 00:00:00

abstract：:The aim was to compare the oral microbial profiles in young adults with an intake of free sugars above or below the current recommendations by the WHO for sugar consumption. Seventy subjects completed a Quantitative Food Frequency Questionnaire to establish the proportion of free sugars in relation to the total energy...

journal_title：Journal of oral microbiology

authors： Keller MK,Kressirer CA,Belstrøm D,Twetman S,Tanner ACR

更新日期：2017-08-01 00:00:00

abstract：:In this study, 181 healthy individuals, including 29 couples, were analysed regarding oral yeast colonization using a culture-based approach. Results showed that 39% of the individuals were yeast carriers, 89% being colonized with Candida albicans, 5% with C. guilliermondi, 3% with C. lusitaniae and 3% with C. parapsi...

journal_title：Journal of oral microbiology

authors： Gerós-Mesquita Â,Carvalho-Pereira J,Franco-Duarte R,Alves A,Gerós H,Pais C,Sampaio P

更新日期：2020-09-14 00:00:00

abstract：:The deleterious and sometimes fatal outcomes of bacterial infectious diseases are the net result of the interactions between the pathogen and the host, and the genetically tractable fruit fly, Drosophila melanogaster, has emerged as a valuable tool for modeling the pathogen-host interactions of a wide variety of bacte...

journal_title：Journal of oral microbiology

authors： Igboin CO,Griffen AL,Leys EJ

更新日期：2012-01-01 00:00:00

abstract：:Inflammasomes are large multiprotein complexes localized in the cytoplasm of the cell. They are responsible for the maturation of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and IL-18 as well as for the activation of inflammatory cell death, the so-called pyroptosis. Inflammasomes assemble in response to...

journal_title：Journal of oral microbiology

authors： Olsen I,Yilmaz Ö

更新日期：2016-02-04 00:00:00

abstract：:Tetracycline resistance can be achieved through tet genes, which code for efflux pumps, ribosomal protection proteins and inactivation enzymes. Some of these genes have only been described in either Gram-positive or Gram-negative bacteria. This is the case of tet(B), which codes for an efflux pump and, so far, had onl...

journal_title：Journal of oral microbiology

authors： Arredondo A,Àlvarez G,Nart J,Mor C,Blanc V,León R

更新日期：2019-07-23 00:00:00

abstract：:Peptidoglycan-associated lipoprotein (PAL) is a conserved pro-inflammatory outer membrane lipoprotein in Gram-negative bacteria. Compared to systemic pathogens, little is known about the virulence properties of PAL in Aggregatibacter actinomycetemcomitans (AaPAL). The aims of this study were to investigate the cytolet...

journal_title：Journal of oral microbiology

authors： Ihalin R,Eneslätt K,Asikainen S

更新日期：2018-03-06 00:00:00

abstract：:Gingivitis is one of the most common oral infections in humans. While sugar alcohols such as erythritol are suggested to have caries-preventive properties, it may also have beneficial effects in prevention of gingivitis by preventing maturation of oral biofilms. The aim of this study was to assess the effect of erythr...

journal_title：Journal of oral microbiology

authors： Janus MM,Volgenant CMC,Brandt BW,Buijs MJ,Keijser BJF,Crielaard W,Zaura E,Krom BP

更新日期：2017-06-22 00:00:00

abstract：:The incidence of opportunistic non-tuberculous mycobacteria (NTM) infections has increased considerably in the past decades causing an array of infections, including respiratory and soft-tissue infections. NTM are ubiquitous and can be found in numerous environments, including households and water plants. However, NTM...

journal_title：Journal of oral microbiology

authors： Macovei L,McCafferty J,Chen T,Teles F,Hasturk H,Paster BJ,Campos-Neto A

更新日期：2015-02-13 00:00:00