Abstract:
:The secretory and autophagy pathways can be thought of as the biosynthetic (i.e., anabolic) and degradative (i.e., catabolic) branches of the endomembrane system. In analogy to anabolic and catabolic pathways in metabolism, there is mounting evidence that the secretory and autophagy pathways are intimately linked and that certain regulatory elements are shared between them. Here we highlight the parallels and points of intersection between these two evolutionarily highly conserved and fundamental endomembrane systems. The intersection of these pathways may play an important role in remodeling membranes during cellular stress.
journal_name
Mol Biol Celljournal_title
Molecular biology of the cellauthors
Farhan H,Kundu M,Ferro-Novick Sdoi
10.1091/mbc.E16-11-0762subject
Has Abstractpub_date
2017-05-01 00:00:00pages
1161-1164issue
9eissn
1059-1524issn
1939-4586pii
28/9/1161journal_volume
28pub_type
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