Calprotectin in Serially Collected Meconium Portions as a Biomarker for Intrauterine Fetal Environment.

abstract：OBJECTIVE:In this prospective study, we assessed the feasibility of foetal RHD genotyping by analysis of DNA extracted from plasma samples of Rhesus (Rh) D-negative pregnant women using real-time PCR and primers and probes targeted toward exon 7 and 10 of RHD gene. METHODS:We analysed 24 RhD-negative pregnant woman an...

journal_title：Fetal diagnosis and therapy

authors： Hromadnikova I,Vechetova L,Vesela K,Benesova B,Doucha J,Kulovany E,Vlk R

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Ectrodactyly is a rare malformation with various presentations. The current report describes a case of ectrodactyly detected using 2-dimensional (2D) and 3-dimensional (3D) ultrasonography at 16 weeks' gestation. METHODS AND RESULTS:The 2D ultrasonographic findings were ectrodactyly in the right hand and mon...

journal_title：Fetal diagnosis and therapy

authors： Koo BS,Baek SJ,Kim MR,Joo WD,Yoo HJ

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:An increasing number of congenital anomalies are diagnosed prenatally. Understanding the implications of these diagnoses on the life of their child is critical for parents, and the surgical consultation is often the primary venue for this education. Little is known about the parent perspective on prenatal ...

journal_title：Fetal diagnosis and therapy

authors： Berman L,Costanzo C,Smola S,Taggi-Pinto A,Luks FL

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To determine the value of routine transvaginal color Doppler assessment of the uterine arteries at 22-24 weeks of gestation in the prediction of placental insufficiency. METHODS:Women with singleton pregnancies scheduled for routine ultrasound scans at 22-24 weeks were offered Doppler assessment of the uteri...

journal_title：Fetal diagnosis and therapy

authors： Palma-Dias RS,Fonseca MM,Brietzke E,Fritsch A,Schlatter D,Maurmann CB,Stein NR,Magalhães JA

更新日期：2008-01-01 00:00:00

abstract：:Five postmortem fetuses were scanned by magnetic resonance (MR) imaging. Of eight three-dimensional (3D) data sets reconstructed on an MGI workstation, five sets demonstrated detailed 3D fetal cardiac structures, and one depicted clear information regarding the disposition and compression of the heart and lungs in dia...

journal_title：Fetal diagnosis and therapy

authors： Deng J,Brookes JA,Gardener JE,Rodeck CH,Lees WR

更新日期：1996-11-01 00:00:00

abstract：:Fetal dextrocardia is a type of cardiac malposition where the major axis from base to apex points to the right side. This condition is usually associated with a wide spectrum of complex cardiac defects. As a result, dextrocardia is conceptually difficult to understand and diagnose on prenatal ultrasound. The advantage...

journal_title：Fetal diagnosis and therapy

authors： Yeo L,Luewan S,Markush D,Gill N,Romero R

更新日期：2018-01-01 00:00:00

abstract：:We present a case where the embryo showed an increased nuchal edema and a metabolic disorder. At 31 weeks of gestation the fetus developed a cardiomegaly and a hydrops. In this case, a long-chain 3-hydroxacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) was confirmed by biochemical investigations in cultured...

journal_title：Fetal diagnosis and therapy

authors： Tercanli S,Uyanik G,Hösli I,Cagdas A,Holzgreve W

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To assess the sonographic visualization of the pericallosal arteries in normal fetuses at 11-13 weeks of gestation using 3D ultrasound. METHODS:We prospectively enrolled women with a singleton pregnancy undergoing ultrasound at 11-13 weeks of gestation. A 3D volume with high-definition power Doppler was acqu...

journal_title：Fetal diagnosis and therapy

authors： Conturso R,Contro E,Bellussi F,Youssef A,Pacella G,Martelli F,Rizzo N,Pilu G,Ghi T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hemimegalencephaly (HMC) is a disorder associated with enlarged and dysplastic hamartomatous overgrowth of all or part of the one cerebral hemisphere that can be isolated or associated with other syndromes. In the normal development of the brain it is important to bear in mind that there are two main process...

journal_title：Fetal diagnosis and therapy

authors： Romero XC,Molina FS,Pastor E,Amaya F

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:This study describes the association between the complexity of congenital cardiac and extracardiac malformations, and the parental decision of pregnancy continuation or termination. METHODS:Congenital heart defects (CHD) was diagnosed by ultrasound in 251 fetuses before the 24th week (23 + 6 weeks) of gestat...

journal_title：Fetal diagnosis and therapy

authors： Nell S,Wijngaarde CA,Pistorius LR,Slieker M,ter Heide H,Manten GT,Freund MW

更新日期：2013-01-01 00:00:00

abstract：:The objectives of the study were to assess the ability of a fetal pulse oximeter to measure the fetal oxygen saturation (SPO2) continuously during labor and to assess the correlation between readings of fetal pulse oximetry and cord blood gases at birth. The Nellcor N-400 Fetal Oximeter was used in 62 women prospectiv...

journal_title：Fetal diagnosis and therapy

authors： Langer B,Boudier E,Haddad J,Pain L,Schlaeder G

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Cytokine imbalance has been implicated in placental-related pathologies, i.e. recurrent miscarriage and pre-eclampsia. Such conditions are more prevalent in multiple pregnancies. Twin-to-twin transfusion syndrome (TTTS) is associated with asymmetric placental blood flow and intra-cardiac pressures. We hypo...

journal_title：Fetal diagnosis and therapy

authors： Fox CE,Lash GE,Pretlove SJ,Chan BC,Holder R,Kilby MD

更新日期：2014-01-01 00:00:00

abstract：:Vein of Galen aneurysmal malformations are rarely seen intracranial malformations. They represent less than 1% of the cerebral arteriovenous malformations. Prenatal diagnosis of an arteriovenous fistula malformation may be achieved by real-time and Doppler sonography with color flow imaging, by identifying dilated vei...

journal_title：Fetal diagnosis and therapy

authors： Paternoster DM,Manganelli F,Moroder W,Nicolini U

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:To determine if: (1) human umbilical cord stem cells could survive for 20 h in extra-embryonic celomic fluid obtained at 40 days of development from baboon pregnancies by ultrasound-guided celocentesis and, (2) human hematopoietic stem cell survival could be enhanced by adding increasing concentrations of he...

journal_title：Fetal diagnosis and therapy

authors： Santolaya-Forgas J,Galan I,Deleon-Luis J,Wolf R

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Cystic fibrosis (CF) is the most common autosomal recessive genetic disorder in the Caucasian population. The molecular diagnosis is difficult since there are about 1,000 mutations in the CF transmembrane regulator gene. The DeltaF508del is the cause of the CF in 64% of the cases in Hungary. Our aim was to co...

journal_title：Fetal diagnosis and therapy

authors： Nagy B,Nagy GR,Lázár L,Bán Z,Papp Z

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:We evaluated the hypothesis that in fetuses with congenital heart disease (CHD) there is a correlation between the expected pattern of in utero brain blood supply and the severity of neurodevelopmental impairment. METHODS:A total of 58 fetuses with CHD and 58 controls underwent a Doppler ultrasound and feta...

journal_title：Fetal diagnosis and therapy

authors： Masoller N,Sanz-Cortés M,Crispi F,Gómez O,Bennasar M,Egaña-Ugrinovic G,Bargalló N,Martínez JM,Gratacós E

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Fetal gene replacement is a novel, potential therapy for monogenic disorders which are diagnosed prenatally. The purpose of this study was to develop in vitro, respiratory-epithelium targeted, lentiviral (LV)-mediated gene transfer in fetal rabbit tracheas. METHODS:Via triple plasmid transfection, vesicular ...

journal_title：Fetal diagnosis and therapy

authors： Huang L,Reebye SC,Yeung AY,Jia WW,Skarsgard ED

更新日期：2006-01-01 00:00:00

abstract：:Characterization of marker chromosomes before the introduction of array CGH (aCGH) assays was only based on their banding patterns (G, C, and NOR staining) and fluorescent in situ hybridization techniques. The use of aCGH greatly improves the identification of marker chromosomes in some cases. We describe an atypical ...

journal_title：Fetal diagnosis and therapy

authors： Lloveras E,Canellas A,Cirigliano V,Català V,Cerdan C,Plaja A

更新日期：2013-01-01 00:00:00

abstract：:A 33-year-old primigravida at 26 weeks gestation presented with fetal hydrops and fetal anemia following prior parvovirus B19 infection. The fetus required two intrauterine transfusions of packed red cells. At 35 weeks gestation, a cesarean section was performed for obstetric reasons. As a consequence of a prenatal bo...

journal_title：Fetal diagnosis and therapy

authors： Schild RL,Plath H,Thomas P,Schulte-Wissermann H,Eis-Hübinger AM,Hansmann M

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the prognosis of monochorionic twins with selective intrauterine growth restriction (sIUGR), classified according to the type of umbilical artery Doppler, under expectant management. METHODS:The outcome of 81 cases with isolated sIUGR was evaluated according to a classification based on umbilica...

journal_title：Fetal diagnosis and therapy

authors： Ishii K,Murakoshi T,Takahashi Y,Shinno T,Matsushita M,Naruse H,Torii Y,Sumie M,Nakata M

更新日期：2009-01-01 00:00:00

abstract：:In this study, we have investigated the maternal effects of distending the uterine cavity with Hartmann's solution in 2nd trimester equivalent pregnant sheep. In 7 pregnant ewes, double endoscopic cannulation of the amniotic cavity was performed under general anesthesia, and 1 liter of Hartmann's solution at 38 degree...

journal_title：Fetal diagnosis and therapy

authors： Evrard VA,Verbeke K,Peers KH,Luks FI,Lerut AE,Vandenberghe K,Deprest JA

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVES:This report wants to focus on the risk of severe prematurity in patients with the hypermobility type of the Ehlers-Danlos syndrome (EDS), a heritable disorder of connective tissue. Although various obstetrical complications have been reported in patients with EDS, most reports specifically comment on the sev...

journal_title：Fetal diagnosis and therapy

authors： De Vos M,Nuytinck L,Verellen C,De Paepe A

更新日期：1999-07-01 00:00:00

abstract：:The possible etiologic roles of infection and bed rest are discussed in connection with a case of maternal homozygous Leiden mutation leading to prematurity, maternal deep-vein thrombosis and neonatal intracranial hemorrhage in a heterozygous premature baby. Maternal bacterial infection and bed rest may trigger deep-v...

journal_title：Fetal diagnosis and therapy

authors： Sikovanyecz J,Orvos H,Pál A,Katona M,Endreffy E,Horváth E,Szabó J

更新日期：2004-05-01 00:00:00

abstract：:Evaluation of the adequacy of fetal growth by measurements of fetal size required theoretical formulae for the assessment of present size from previous measurements. The various models presented in the literature assume the same mathematical formula for the whole pregnancy. In this study, a model of different polynomi...

journal_title：Fetal diagnosis and therapy

authors： Nitzan M,Tadmor OP,Skomorowski Y,Rabinowitz R,Diamant Y

更新日期：1994-09-01 00:00:00

abstract：:We report prenatal diagnostic studies for metaphyseal chondrodysplasia of the Schmid type. Identification of a specific COL10A1 gene mutation in an affected father allowed prenatal diagnosis by chorionic villus sampling in a twin pregnancy. Neither of the nonidentical twins received the abnormal COL10A1 gene from thei...

journal_title：Fetal diagnosis and therapy

authors： Milunsky J,Maher T,Lebo R,Milunsky A

更新日期：1998-05-01 00:00:00

abstract：:We report a case of sirenomelia diagnosed at 13 gestational weeks. This rare malformation sequence is characterized by fusion and rotation of the lower limbs to various degrees and anorectal atresia, usually associated with absence of bladder and agenesis or dysgenesis of the kidneys. Diagnosis is commonly made later ...

journal_title：Fetal diagnosis and therapy

authors： Carbillon L,Seince N,Largillière C,Bucourt M,Uzan M

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of smoking and number of previous births on maternal serum levels of alpha-fetoprotein and free beta-subunit of human chorionic gonadotropin (free beta-hCG). METHODS:The study included 3,252 completed unaffected singleton pregnancies that proceeded beyond 37 weeks' gestation and result...

journal_title：Fetal diagnosis and therapy

authors： Tislarić D,Brajenović-Milić B,Ristić S,Latin V,Zuvić-Butorac M,Bacić J,Petek M,Kapović M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the rate of pulmonary stenosis and functional pulmonary atresia (PS/PA) in recipient twins prior to fetal surgery for twin-twin transfusion syndrome (TTTS) and their pre- and postnatal outcomes. METHODS:We carried out a prospective study including 260 cases of TTTS. Echocardiography was performed...

journal_title：Fetal diagnosis and therapy

authors： Ortiz JU,Masoller N,Gómez O,Bennasar M,Eixarch E,Lobmaier SM,Crispi F,Gratacos E,Martinez JM

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To describe procedure-related complications and perinatal survival after intrauterine transfusion (IUT) before 20 weeks of gestation in fetuses with severe anemia due to human parvovirus B19 infection. MATERIALS AND METHODS:A retrospective study was conducted of all fetuses requiring IUT before 20 weeks of g...

journal_title：Fetal diagnosis and therapy

authors： Hellmund A,Geipel A,Berg C,Bald R,Gembruch U

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Forty percent of Down syndrome (DS) fetuses have congenital heart defects (CHD). An abnormal angiogenic environment has been described in euploid fetuses with CHD. However, the underlying pathophysiologic pathway that contributes to CHD in DS remains unknown. The objective was to compare the expression of ...

journal_title：Fetal diagnosis and therapy

authors： Sánchez O,Domínguez C,Ruiz A,Ribera I,Alijotas J,Cabero L,Carreras E,Llurba E

更新日期：2016-01-01 00:00:00