当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Gray-matter structural variability in the human cerebellum: Lobule-specific differences across sex and hemisphere.

Gray-matter structural variability in the human cerebellum: Lobule-specific differences across sex and hemisphere.

Abstract：

:Though commonly thought of as a "motor structure", we now know that the cerebellum's reciprocal connections to the cerebral cortex underlie contributions to both motor and non-motor behavior. Further, recent research has shown that cerebellar dysfunction may contribute to a wide range of neuropsychiatric disorders. However, there has been little characterization of normative variability at the level of cerebellar structure that can facilitate and further our understanding of disease biomarkers. In this manuscript we examine normative variation of the cerebellum using data from the Human Connectome Project (HCP). The Multiple Automatically Generated Templates (MAGeT) segmentation tool was used to identify the cerebella and 33 anatomically-defined lobules from 327 individuals from the HCP. To characterize normative variation, we estimated population mean volume and variability, assessed differences in hemisphere and sex, and related lobular volume to motor and non-motor behavior. We found that the effects of hemisphere and sex were not homogeneous across all lobules of the cerebellum. Greater volume in the right hemisphere was primarily driven by lobules Crus I, II, and H VIIB, with H VIIIA exhibiting the greatest left>right asymmetry. Relative to total cerebellar gray-matter volume, females had larger Crus II (known to be connected with non-motor regions of the cerebral cortex) while males had larger motor-connected lobules including H V, and VIIIA/B. When relating lobular volume to memory, motor performance, and emotional behavior, we found some evidence for relationships that have previously been identified in the literature. Our observations of normative cerebellar structure and variability in young adults provide evidence for lobule-specific differences in volume and the relationship with sex and behavior - indicating that the cerebellum cannot be considered a single structure with uniform function, but as a set of regions with functions that are likely as diverse as their connectivity with the cerebral cortex.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Steele CJ,Chakravarty MM

doi

10.1016/j.neuroimage.2017.04.066

subject

Has Abstract

pub_date

2018-04-15 00:00:00

pages

164-173

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(17)30385-3

journal_volume

170

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • Intersubject similarity of personality is associated with intersubject similarity of brain connectivity patterns.

    abstract：:Personality is a central high-level psychological concept that defines individual human beings and has been associated with a variety of real-world outcomes (e.g., mental health and academic performance). Using 2 h, high resolution, functional magnetic resonance imaging (fMRI) resting state data of 984 (primary datase...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.10.062

    authors： Liu W,Kohn N,Fernández G

    更新日期：2019-02-01 00:00:00

  • Multivariate analysis of neuronal interactions in the generalized partial least squares framework: simulations and empirical studies.

    abstract：:Identification of spatiotemporal interactions within/between neuron populations is critical for detection and characterization of large-scale neuronal interactions underlying perception, cognition, and behavior. Univariate analysis has been employed successfully in many neuroimaging studies. However, univariate analys...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/S1053-8119(03)00333-1

    authors： Lin FH,McIntosh AR,Agnew JA,Eden GF,Zeffiro TA,Belliveau JW

    更新日期：2003-10-01 00:00:00

  • Novel artefact removal algorithms for co-registered EEG/fMRI based on selective averaging and subtraction.

    abstract：:Co-registered EEG and functional MRI (EEG/fMRI) is a potential clinical tool for planning invasive EEG in patients with epilepsy. In addition, the analysis of EEG/fMRI data provides a fundamental insight into the precise physiological meaning of both fMRI and EEG data. Routine application of EEG/fMRI for localization ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.09.022

    authors： de Munck JC,van Houdt PJ,Gonçalves SI,van Wegen E,Ossenblok PP

    更新日期：2013-01-01 00:00:00

  • Dynamic intra- and interhemispheric interactions during unilateral and bilateral hand movements assessed with fMRI and DCM.

    abstract：:Any motor action results from a dynamic interplay of various brain regions involved in different aspects of movement preparation and execution. Establishing a reliable model of how these areas interact is crucial for a better understanding of the mechanisms underlying motor function in both healthy subjects and patien...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.03.048

    authors： Grefkes C,Eickhoff SB,Nowak DA,Dafotakis M,Fink GR

    更新日期：2008-07-15 00:00:00

  • Resting state functional atlas and cerebral networks in mouse lemur primates at 11.7 Tesla.

    abstract：:Measures of resting-state functional connectivity allow the description of neuronal networks in humans and provide a window on brain function in normal and pathological conditions. Characterizing neuronal networks in animals is complementary to studies in humans to understand how evolution has modelled network archite...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117589

    authors： Garin CM,Nadkarni NA,Landeau B,Chételat G,Picq JL,Bougacha S,Dhenain M

    更新日期：2021-02-01 00:00:00

  • Cardiac and respiration-induced brain deformations in humans quantified with high-field MRI.

    abstract：:Microvascular blood volume pulsations due to the cardiac and respiratory cycles induce brain tissue deformation and, as such, are considered to drive the brain's waste clearance system. We have developed a high-field magnetic resonance imaging (MRI) technique to quantify both cardiac and respiration-induced tissue def...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116581

    authors： Sloots JJ,Biessels GJ,Zwanenburg JJM

    更新日期：2020-04-15 00:00:00

  • Thalamic low frequency activity facilitates resting-state cortical interhemispheric MRI functional connectivity.

    abstract：:Blood-oxygen-level-dependent (BOLD) resting-state functional MRI (rsfMRI) has emerged as a valuable tool to map complex brain-wide functional networks, predict cognitive performance and identify biomarkers for neurological diseases. However, interpreting these findings poses challenges, as the neural basis of rsfMRI c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.06.063

    authors： Wang X,Leong ATL,Chan RW,Liu Y,Wu EX

    更新日期：2019-11-01 00:00:00

  • Individual differences in reinforcement learning: behavioral, electrophysiological, and neuroimaging correlates.

    abstract：:During reinforcement learning, phasic modulations of activity in midbrain dopamine neurons are conveyed to the dorsal anterior cingulate cortex (dACC) and basal ganglia (BG) and serve to guide adaptive responding. While the animal literature supports a role for the dACC in integrating reward history over time, most hu...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.05.032

    authors： Santesso DL,Dillon DG,Birk JL,Holmes AJ,Goetz E,Bogdan R,Pizzagalli DA

    更新日期：2008-08-15 00:00:00

  • Direct segmentation of the major white matter tracts in diffusion tensor images.

    abstract：:Diffusion-weighted images of the human brain are acquired more and more routinely in clinical research settings, yet segmenting and labeling white matter tracts in these images is still challenging. We present in this paper a fully automated method to extract many anatomical tracts at once on diffusion tensor images, ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.06.020

    authors： Bazin PL,Ye C,Bogovic JA,Shiee N,Reich DS,Prince JL,Pham DL

    更新日期：2011-09-15 00:00:00

  • Cortical activation to auditory mismatch elicited by frequency deviant and complex novel sounds: a PET study.

    abstract：:The analysis of auditory deviant events outside the focus of attention is a fundamental capacity of human information processing and has been studied in experiments on Mismatch Negativity (MMN) and the P3a component in evoked potential research. However, generators contributing to these components are still under disc...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1006/nimg.2002.1176

    authors： Müller BW,Jüptner M,Jentzen W,Müller SP

    更新日期：2002-09-01 00:00:00

  • Changes of individual BrainAGE during the course of the menstrual cycle.

    abstract：:Brain morphology varies during the course of the menstrual cycle, with increases in individual gray matter volume at the time of ovulation. This study implemented our previously presented BrainAGE framework to analyze short-term neuroanatomical changes in healthy young women due to hormonal changes during the menstrua...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.04.036

    authors： Franke K,Hagemann G,Schleussner E,Gaser C

    更新日期：2015-07-15 00:00:00

  • Subject-specific functional parcellation via prior based eigenanatomy.

    abstract：:We present a new framework for prior-constrained sparse decomposition of matrices derived from the neuroimaging data and apply this method to functional network analysis of a clinically relevant population. Matrix decomposition methods are powerful dimensionality reduction tools that have found widespread use in neuro...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.05.026

    authors： Dhillon PS,Wolk DA,Das SR,Ungar LH,Gee JC,Avants BB

    更新日期：2014-10-01 00:00:00

  • Frequency-specific task modulation of human brain functional networks: A fast fMRI study.

    abstract：:How coherent neural oscillations are involved in task execution is a fundamental question in neuroscience. Although several electrophysiological studies have tackled this issue, the brain-wide task modulation of neural coherence remains uncharacterized. Here, with a fast fMRI technique, we studied shifts of brain-wide...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117375

    authors： Sasai S,Koike T,Sugawara SK,Hamano YH,Sumiya M,Okazaki S,Takahashi HK,Taga G,Sadato N

    更新日期：2021-01-01 00:00:00

  • Phonological processing in deaf signers and the impact of age of first language acquisition.

    abstract：:Just as words can rhyme, the signs of a signed language can share structural properties, such as location. Linguistic description at this level is termed phonology. We report that a left-lateralised fronto-parietal network is engaged during phonological similarity judgements made in both English (rhyme) and British Si...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.12.047

    authors： MacSweeney M,Waters D,Brammer MJ,Woll B,Goswami U

    更新日期：2008-04-15 00:00:00

  • Source stability index: a novel beamforming based localisation metric.

    abstract：:Many experimental studies into human brain function now use magnetoencephalography (MEG) to non-invasively investigate human neuronal activity. A number of different analysis techniques use the observed magnetic fields outside of the head to estimate the location and strength of the underlying neural generators. One s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.09.055

    authors： Hymers M,Prendergast G,Johnson SR,Green GG

    更新日期：2010-01-15 00:00:00

  • Real-time feedback optimization of z-shim gradient for automatic compensation of susceptibility-induced signal loss in EPI.

    abstract：:Signal loss in gradient-echo echo planar imaging (GE-EPI) due to susceptibility-induced magnetic field inhomogeneity makes it difficult to assess the blood oxygenation level-dependent (BOLD) effect in fMRI investigations. The z-shim method that applies an additional gradient moment is one of the more popular methods o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.01.045

    authors： Tang YW,Huang TY

    更新日期：2011-04-15 00:00:00

  • A PET imaging study of 5-HT(1A) receptors in cat brain after acute and chronic fluoxetine treatment.

    abstract：:Immuno-electron microscopic and beta-microprobe studies have demonstrated that the internalization of serotonin 5-HT(1A) autoreceptors, after acute treatment with the selective 5-HT(1A) receptor agonist 8-OH-DPAT or with the specific serotonin reuptake inhibitor (SSRI) fluoxetine, is associated with a marked decrease ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.08.012

    authors： Aznavour N,Rbah L,Riad M,Reilhac A,Costes N,Descarries L,Zimmer L

    更新日期：2006-11-15 00:00:00

  • Construction of a consistent high-definition spatio-temporal atlas of the developing brain using adaptive kernel regression.

    abstract：:Medical imaging has shown that, during early development, the brain undergoes more changes in size, shape and appearance than at any other time in life. A better understanding of brain development requires a spatio-temporal atlas that characterizes the dynamic changes during this period. In this paper we present an ap...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.09.062

    authors： Serag A,Aljabar P,Ball G,Counsell SJ,Boardman JP,Rutherford MA,Edwards AD,Hajnal JV,Rueckert D

    更新日期：2012-02-01 00:00:00

  • Reduced caudate volume and enhanced striatal-DMN integration in chess experts.

    abstract：:The superior capability of chess experts largely depends on quick automatic processing skills which are considered to be mediated by the caudate nucleus. We asked whether continued practice or rehearsal of the skill over a long period of time can lead to structural changes in this region. We found that, comparing to n...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.01.047

    authors： Duan X,He S,Liao W,Liang D,Qiu L,Wei L,Li Y,Liu C,Gong Q,Chen H

    更新日期：2012-04-02 00:00:00

  • The effects of age on reward magnitude processing in the monetary incentive delay task.

    abstract：:Previous studies have suggested age-related differences in reward-directed behavior and cerebral processes in support of the age effects. However, it remains unclear how age may influence the processing of reward magnitude. Here, with 54 volunteers (22-74 years of age) participating in the Monetary Incentive Delay Tas...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116368

    authors： Dhingra I,Zhang S,Zhornitsky S,Le TM,Wang W,Chao HH,Levy I,Li CR

    更新日期：2020-02-15 00:00:00

  • Automated template-based brain localization and extraction for fetal brain MRI reconstruction.

    abstract：:Most fetal brain MRI reconstruction algorithms rely only on brain tissue-relevant voxels of low-resolution (LR) images to enhance the quality of inter-slice motion correction and image reconstruction. Consequently the fetal brain needs to be localized and extracted as a first step, which is usually a laborious and tim...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.04.004

    authors： Tourbier S,Velasco-Annis C,Taimouri V,Hagmann P,Meuli R,Warfield SK,Bach Cuadra M,Gholipour A

    更新日期：2017-07-15 00:00:00

  • Intrinsic, dynamic and effective connectivity among large-scale brain networks modulated by oxytocin.

    abstract：:The neuropeptide oxytocin is a key modulator of social-emotional behavior and its intranasal administration can influence the functional connectivity of brain networks involved in the control of attention, emotion and reward reported in humans. However, no studies have systematically investigated the effects of oxytoc...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117668

    authors： Jiang X,Ma X,Geng Y,Zhao Z,Zhou F,Zhao W,Yao S,Yang S,Zhao Z,Becker B,Kendrick KM

    更新日期：2020-12-24 00:00:00

  • Pyramidal tract lesions and movement-associated cortical recruitment in patients with MS.

    abstract：:Cortical functional changes, with the potential to limit the functional consequences of tissue injury, have been shown in patients with multiple sclerosis (MS). In this study, we assessed the influence of MS-related tissue damage of the brain portion of the left pyramidal tract on the corresponding movement-associated...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.05.005

    authors： Rocca MA,Gallo A,Colombo B,Falini A,Scotti G,Comi G,Filippi M

    更新日期：2004-09-01 00:00:00

  • Attractor concretion as a mechanism for the formation of context representations.

    abstract：:Complex tasks often require the memory of recent events, the knowledge about the context in which they occur, and the goals we intend to reach. All this information is stored in our mental states. Given a set of mental states, reinforcement learning (RL) algorithms predict the optimal policy that maximizes future rewa...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.01.047

    authors： Rigotti M,Ben Dayan Rubin D,Morrison SE,Salzman CD,Fusi S

    更新日期：2010-09-01 00:00:00

  • Statistical power and prediction accuracy in multisite resting-state fMRI connectivity.

    abstract：:Connectivity studies using resting-state functional magnetic resonance imaging are increasingly pooling data acquired at multiple sites. While this may allow investigators to speed up recruitment or increase sample size, multisite studies also potentially introduce systematic biases in connectivity measures across sit...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.01.072

    authors： Dansereau C,Benhajali Y,Risterucci C,Pich EM,Orban P,Arnold D,Bellec P

    更新日期：2017-04-01 00:00:00

  • Developmental neural networks in children performing a Categorical N-Back Task.

    abstract：:The prefrontal and temporal networks subserving object working memory tasks in adults have been reported as immature in young children; yet children are adequately capable of performing such tasks. We investigated the basis of this apparent contradiction using a complex object working memory task, a Categorical n-back...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.07.028

    authors： Ciesielski KT,Lesnik PG,Savoy RL,Grant EP,Ahlfors SP

    更新日期：2006-11-15 00:00:00

  • Joint neuronal tuning for object form and position in the human lateral occipital complex.

    abstract：:A long-standing heuristic in visual neuroscience holds that extrastriate visual cortex is parceled into a dorsal "where" pathway concerned with stimulus position and motion and a ventral "what" pathway concerned with stimulus form. Several recent studies using functional magnetic resonance imaging (fMRI), however, hav...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.08.043

    authors： MacEvoy SP,Yang Z

    更新日期：2012-12-01 00:00:00

  • Artificial shifting of fMRI activation localized by volume- and surface-based analyses.

    abstract：:Spatial smoothing is an important post-processing procedure that is used to increase the signal-to-noise ratio (SNR) of blood oxygenation level-dependent signals (BOLD) in common functional magnetic resonance imaging (fMRI) applications. However, recent studies have shown that smoothing artificially shifts probabilist...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.12.036

    authors： Jo HJ,Lee JM,Kim JH,Choi CH,Gu BM,Kang DH,Ku J,Kwon JS,Kim SI

    更新日期：2008-04-15 00:00:00

  • Combined MEG and EEG show reliable patterns of electromagnetic brain activity during natural viewing.

    abstract：:Naturalistic stimuli such as movies are increasingly used to engage cognitive and emotional processes during fMRI of brain hemodynamic activity. However, movies have been little utilized during magnetoencephalography (MEG) and EEG that directly measure population-level neuronal activity at a millisecond resolution. He...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.03.066

    authors： Chang WT,Jääskeläinen IP,Belliveau JW,Huang S,Hung AY,Rossi S,Ahveninen J

    更新日期：2015-07-01 00:00:00

  • Gradient and shim technologies for ultra high field MRI.

    abstract：:Ultra High Field (UHF) MRI requires improved gradient and shim performance to fully realize the promised gains (SNR as well as spatial, spectral, diffusion resolution) that higher main magnetic fields offer. Both the more challenging UHF environment by itself, as well as the higher currents used in high performance co...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2016.11.033

    authors： Winkler SA,Schmitt F,Landes H,de Bever J,Wade T,Alejski A,Rutt BK

    更新日期：2018-03-01 00:00:00