Derivation of predicted no-effect concentration and ecological risk for atrazine better based on reproductive fitness.


:Atrazine (ATZ) is an herbicide most commonly used in China and other regions of the world. It is reported toxic to aquatic organisms, and frequently occurs at relatively high concentrations. Currently, ATZ has been proved to affect reproduction of aquatic species at much lower levels. So it is controversial to perform ecological risk assessment using predicted no-effect concentrations (PENCs) derived from traditional endpoints, which fail to provide adequate protection to aquatic organisms. In this study, PNECs of ATZ were derived based on six endpoints of survival, growth, behavior, biochemistry, genetics and reproduction. The PNEC derived from reproductive lesion was 0.044μg ATZ L-1, which was obviously lower than that derived from other endpoints. In addition, a tiered ecological risk assessment was conducted in the Taizi River based on six PNECs derived from six categories of toxicity endpoints. Results of these two methods of ecological risk assessment were consistent with each other, and the risk level of ATZ to aquatic organisms reached highest as taking reproductive fitness into account. The joint probability indicated that severe ecological risk rooting in reproduction might exist 93.9% and 99.9% of surface water in the Taizi River, while 5% threshold (HC5) and 1% threshold (HC1) were set up to protect aquatic organisms, respectively. We hope the present work could provide valuable information to manage and control ATZ pollution.


Ecotoxicol Environ Saf


Zheng L,Zhang Y,Yan Z,Zhang J,Li L,Zhu Y,Zhang Y,Zheng X,Wu J,Liu Z




Has Abstract


2017-08-01 00:00:00












  • Biodecontamination of water from bisphenol A using ligninolytic fungi and the modulation role of humic acids.

    abstract::Bisphenol A (BPA) is an endocrine disruptor compound (EDC) of xenobiotic origin occurring in natural waters and wastewaters, especially in the most industrialized and urbanized areas. Recent investigations report the use of ligninolytic fungi for the removal of aromatic contaminants, including some EDCs, from differen...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Loffredo E,Traversa A,Senesi N

    更新日期:2012-05-01 00:00:00

  • Adaptation of the fish juvenile growth test (OECD TG 215, 2000) to the marine species Dicentrarchus labrax.

    abstract::The OECD TG 215 method (2000) (C.14 method of EC Regulation 440/2008) was developed on the rainbow trout (Oncorynchus mykiss) to assess chronic toxicity (28d) of chemicals on fish juveniles. It contemplates to use other well documented species identifying suitable conditions to evaluate their growth. OECD proposes the...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Tornambè A,Manfra L,Canepa S,Oteri F,Martuccio G,Cicero AM,Magaletti E

    更新日期:2018-02-01 00:00:00

  • Food limitation in Chironomus tepperi: effects on survival, sex ratios and development across two generations.

    abstract::Species from the Dipteran family Chironomidae are widely used in laboratory and field studies to identify toxicity in freshwater environments. However, toxicity assessments can be influenced by food availability, which can alter endpoints in assays including viability, sex ratios and development time. The aim of this ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Townsend KR,Pettigrove VJ,Hoffmann AA

    更新日期:2012-10-01 00:00:00

  • Interactive toxic effects of heavy metals and humic acids on Vibrio fischeri.

    abstract::The effect of humic acids (HAs) on the toxicity of copper, zinc, and lead was investigated using the photobacterium Vibrio fischeri (Microtox test) as a test organism. The effects of HAs on metal toxicity were evaluated as functions of time and concentration in pure compound solutions. The toxicities of copper and lea...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Tsiridis V,Petala M,Samaras P,Hadjispyrou S,Sakellaropoulos G,Kungolos A

    更新日期:2006-01-01 00:00:00

  • Environmentally relevant concentrations of benzo[a]pyrene affect steroid levels and affect gonad of male scallop Chlamys farreri.

    abstract::Sexually mature male Chlamys farreri were exposed to benzo[a]pyrene for 10 days at four concentrations at 0, 0.025, 0.5 and 10 μg/L. Fluctuations in sex steroids during the exposure period were observed, which indicated that sex steroids have a role in gamete development. Exposure to B[a]P altered levels of 17β-estrad...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Tian S,Pan L,Tao Y,Sun X

    更新日期:2015-04-01 00:00:00

  • Relation of tributyltin and triphenyltin equilibrium sorption and kinetic accumulation in carp and Ceratophyllum demersum.

    abstract::Comparatively limited knowledge is known about the accumulation processes of tributyltin (TBT) and triphenyltin (TPT) in fish and aquatic plant in the freshwater environment, which has hindered a full understanding of their bioaccumulation potential and ecological risks. In the present study, sorption of TBT and TPT o...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Xiao X,Zhu S,Zou X,He G,Jiang J,Sheng GD

    更新日期:2020-04-01 00:00:00

  • Acute and subacute toxicity study of inhaled methyl isocyanate in Charles Foster rats.

    abstract::Charles Foster male and female rats were exposed only once to 3.52 and 35.32 ppm doses of methyl isocyanate in separate experiments for 10 min each in an acute toxicity study, while in subacute toxicity experiments, they were exposed to 0.212, 0.265, and 0.349 ppm doses for 30 min daily, for 6 days, by inhalation. Cli...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Sethi N,Dayal R,Singh RK

    更新日期:1989-08-01 00:00:00

  • Detection and fate of antibiotic resistant bacteria in wastewater treatment plants: a review.

    abstract::Antibiotics are among the most successful group of pharmaceuticals used for human and veterinary therapy. However, large amounts of antibiotics are released into municipal wastewater due to incomplete metabolism in humans or due to disposal of unused antibiotics, which finally find their ways into different natural en...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章,评审


    authors: Bouki C,Venieri D,Diamadopoulos E

    更新日期:2013-05-01 00:00:00

  • Remediation of lead polluted soil by active silicate material prepared from coal fly ash.

    abstract::To improve the effect of coal fly ash on the remediation of heavy metal polluted soils, the active silicate material (ASM) was prepared by coal fly ash and the remediation of lead polluted soils by ASM was investigated in this study. To study the reaction mechanism between ASM and Pb(II) in soil, the Pb(II) adsorption...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Lei C,Chen T,Zhang QY,Long LS,Chen Z,Fu ZP

    更新日期:2020-12-15 00:00:00

  • Some silica-based double salts as ion exchangers useful in the treatment of industrial effluents and control of pollutants.

    abstract::A systematic comparative study has been performed on the various double salts based on silica. They are found to be more stable chemically and thermally than single salts of this type. Furthermore, these materials have a better selectivity for some pollutants chiefly found in the effluents of dyestuff and plating indu...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Varshney KG

    更新日期:1989-04-01 00:00:00

  • Trace element concentrations in harvested auks from Newfoundland: Toxicological risk of a traditional hunt.

    abstract::Common (Uria aalge) and Thick-billed Murres (Uria lomvia) are apex predators in the North Atlantic Ocean, and are also subject to a traditional hunt in Newfoundland and Labrador during the winter months, along with small numbers of illegally harvested Razorbills (Alca torda). Because of their high trophic position, au...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Bond AL,Robertson GJ,Lavers JL,Hobson KA,Ryan PC

    更新日期:2015-05-01 00:00:00

  • Effects of dietary Pb(II) and tributyltin on neotropical fish, Hoplias malabaricus: histopathological and biochemical findings.

    abstract::Trahira (Hoplias malabaricus) used to investigate the effects of successive Pb(II) or tributyltin (TBT) dietary doses. After 70 days of acclimation, individuals were exposed to 21 microg Pbg(-1) or 0.3 microg TBTg(-1) (5-day intervals, 14 doses). Two experiments were conducted to investigate the histopathological effe...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Rabitto IS,Alves Costa JR,Silva de Assis HC,Pelletier EE,Akaishi FM,Anjos A,Randi MA,Oliveira Ribeiro CA

    更新日期:2005-02-01 00:00:00

  • Bioaccumulation and toxicity of copper in outdoor freshwater microcosms.

    abstract::This study characterizes the effects of copper (Cu) on Florida apple snails (Pomacea paludosa) and mosquito fish (Gambusia affinis) using a replicated outdoor microcosm design. Soils used in this study were collected from two Cu-enriched citrus agricultural sites in South Florida (Agler property (AGLR) in St. Lucie Co...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Hoang TC,Pryor RL,Rand GM,Frakes RA

    更新日期:2011-05-01 00:00:00

  • Antibiotics promoted the recovery of Microcystis aeruginosa after UV-B radiation at cellular and proteomic levels.

    abstract::Elevated UV-B radiation due to ozone layer depletion may prevent the growth of bloom-forming cyanobacteria in aquatic environments, while antibiotic contaminants may cause effects opposite to that of UV-B due to hormesis. This study investigated the influence of a quaternary antibiotic mixture on Microcystis aeruginos...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Jiang Y,Liu Y,Zhang J,Gao B

    更新日期:2020-03-01 00:00:00

  • Mimicking natural systems: Changes in behavior as a result of dynamic exposure to naproxen.

    abstract::Animals living in aquatic habitats regularly encounter anthropogenic chemical pollution. Typically, the toxicity of a chemical toxicant is determined by the median lethal concentration (LC50) through a static exposure test. However, LC50 values and static tests do not provide an accurate representation of exposure to ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Neal AE,Moore PA

    更新日期:2017-01-01 00:00:00

  • Association between low-to-moderate fluoride exposure and bone mineral density in Chinese adults: Non-negligible role of RUNX2 promoter methylation.

    abstract::Bone mineral density (BMD) changes were reported to be associated with excessive fluoride exposure and abnormal expression of RUNX2. However, whether the alteration of methylation status, a most commonly used marker for the alteration of gene expression in epidemiological investigation, of RUNX2 is associated with low...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Gao M,Sun L,Xu K,Zhang L,Zhang Y,He T,Sun R,Huang H,Zhu J,Zhang Y,Zhou G,Ba Y

    更新日期:2020-10-15 00:00:00

  • Microarray analysis of di-n-butyl phthalate and 17α ethinyl-oestradiol responses in three-spined stickleback testes reveals novel candidate genes for endocrine disruption.

    abstract::Phthalate esters are plasticizers frequently found in wastewater effluents. Previous studies on phthalates have reported anti-androgenic activity in mammals, causing concerns of their potential effects on the reproduction of aquatic organisms. Another group of environmental endocrine disrupters, steroidal estrogens, a...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Prokkola JM,Katsiadaki I,Sebire M,Elphinstone-Davis J,Pausio S,Nikinmaa M,Leder EH

    更新日期:2016-02-01 00:00:00

  • Target and non-target toxicity of botanical insecticide derived from Couroupita guianensis L. flower against generalist herbivore, Spodoptera litura Fab. and an earthworm, Eisenia foetida Savigny.

    abstract::Botanical insecticides may provide alternatives to synthetic insecticides for controlling Spodoptera litura (F.) and they are target specific, biodegradable, and harmless to mammals. Eight natural chemical compounds with larvicidal activity were identified from fraction F6 of C. guianensis flower extract. Probit analy...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Ponsankar A,Vasantha-Srinivasan P,Senthil-Nathan S,Thanigaivel A,Edwin ES,Selin-Rani S,Kalaivani K,Hunter WB,Alessandro RT,Abdel-Megeed A,Paik CH,Duraipandiyan V,Al-Dhabi NA

    更新日期:2016-11-01 00:00:00

  • Evaluation of sugar-cane vinasse treated with Pleurotus sajor-caju utilizing aquatic organisms as toxicological indicators.

    abstract::Toxicity tests with aquatic organisms constitute an effective tool in the evaluation, prediction and detection of the potential effect of pollutants from environmental samples in living organisms. Vinasse, a highly colored effluent, is a sub-product rich in nutrients, mainly organic matter, with high pollutant potenti...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Ferreira LF,Aguiar MM,Messias TG,Pompeu GB,Lopez AM,Silva DP,Monteiro RT

    更新日期:2011-01-01 00:00:00

  • DNA damage and micronuclei in parthenogenetic and bisexual Darevskia rock lizards from the areas with different levels of soil pollution.

    abstract::Natural species are widely used as indicator organisms to estimate of the impact of environmental pollution. Here we present the results of first study of a reliability of parthenogenetic Darevskia аrmeniaca and bisexual Darevskia raddei rock lizards as sentinels for monitoring of environmental genotoxicity. The comet...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Simonyan A,Hovhannisyan G,Sargsyan A,Arakelyan M,Minasyan S,Aroutiounian R

    更新日期:2018-06-15 00:00:00

  • Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor α (PPARα).

    abstract::Short-chain chlorinated paraffins (SCCPs) are frequently detected in environmental matrices and human tissues. It was hypothesized that SCCPs might interact with the peroxisome proliferator-activated receptor α (PPARα). In the present study, an in vitro, dual-luciferase reporter gene assay and in silico molecular dock...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Gong Y,Zhang H,Geng N,Ren X,Giesy JP,Luo Y,Xing L,Wu P,Yu Z,Chen J

    更新日期:2019-10-15 00:00:00

  • Responses in the crucian carp (Carassius auratus) exposed to environmentally relevant concentration of 17α-Ethinylestradiol based on metabolomics.

    abstract::17α-ethynylestradiol (EE2), a ubiquitous synthetic endocrine disrupting chemical, was the principal component of contraceptive drugs and one of common hormone medications. The detrimental impact of EE2 on the reproduction of organisms was widely recognized. However, the underlying mechanisms of physiological and metab...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Zhou X,Li Y,Li H,Yang Z,Zuo C

    更新日期:2019-11-15 00:00:00

  • Suppression of hippocampal slice excitability by 2-, 3-, and 4-methylpyridine.

    abstract::The present study assessed the effects of 2-, 3-, and 4-methylpyridine on rat hippocampal slice excitability. Tests of excitatory and inhibitory systems in area CA1 of the hippocampal slice were conducted over a period of 3 h postexposure. Following exposures of 100 microM 2-, 3-, or 4-methylpyridine, evoked populatio...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Fountain SB,Teyler TJ

    更新日期:2001-03-01 00:00:00

  • Warfarin-exposed zebrafish embryos resembles human warfarin embryopathy in a dose and developmental-time dependent manner - From molecular mechanisms to environmental concerns.

    abstract::Warfarin is the most worldwide used anticoagulant drug and rodenticide. Since it crosses placental barrier it can induce warfarin embryopathy (WE), a fetal mortality in neonates characterized by skeletal deformities in addition to brain hemorrhages. Although the effects of warfarin exposure in aquatic off target speci...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Granadeiro L,Dirks RP,Ortiz-Delgado JB,Gavaia PJ,Sarasquete C,Laizé V,Cancela ML,Fernández I

    更新日期:2019-10-15 00:00:00

  • Mitophagy-lysosomal pathway is involved in silver nanoparticle-induced apoptosis in A549 cells.

    abstract::With the increasing use of silver nanoparticles (AgNPs) in biological materials, the cytotoxicity caused by these particles has attracted much attention. However, the molecular mechanism underlying AgNP cytotoxicity remains unclear. In this study, we aimed to systematically investigate the toxicity induced by AgNP exp...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Li J,Chang X,Shang M,Niu S,Zhang W,Zhang B,Huang W,Wu T,Zhang T,Tang M,Xue Y

    更新日期:2021-01-15 00:00:00

  • Putative environmental levels of levofloxacin facilitate the dissemination of antibiotic-resistant Escherichia coli via plasmid-mediated transformability.

    abstract::Antibiotic residues in the environment pose a great risk to global public health. They increase antibiotic resistance by enhancing plasmid conjugation among bacteria or mutations within bacterial genomes. However, little is known about whether the putative environmental levels of antibiotics are sufficient to influenc...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Wu HY,Shi DY,Yang D,Yin J,Yang ZW,Li JW,Yang W,Jin M

    更新日期:2020-06-01 00:00:00

  • Mercury accumulation patterns and biochemical endpoints in wild fish (Liza aurata): a multi-organ approach.

    abstract::The integration of bioaccumulation and effect biomarkers in fish has been proposed for risk evaluation of aquatic contaminants. However, this approach is still uncommon, namely in the context of mercury contamination. Furthermore, a multi-organ evaluation allows an overall account of the organisms' condition. Having i...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Mieiro CL,Duarte AC,Pereira ME,Pacheco M

    更新日期:2011-11-01 00:00:00

  • Improvement of cyanobacterial-killing biologically derived substances (BDSs) using an ecologically safe and cost-effective naphthoquinone derivative.

    abstract::In previous studies, naphthoquinone (NQ) compounds have been shown to be effective, selective, and ecologically safe algicides for controlling harmful algal blooming species (HABs) or winter bloom species, such as Stephanodiscus hantzschii. However, there are no reports on NQ-based algicides for use with cyanobacteria...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Joo JH,Wang P,Park BS,Byun JH,Choi HJ,Kim SH,Han MS

    更新日期:2017-07-01 00:00:00

  • Possible side effects of airborne pesticides on fungi and vascular plants in The Netherlands.

    abstract::A survey of the potential side effects of volatilized pesticides on fungi and vascular plants in The Netherlands has been made for two herbicides (atrazine and MCPA), a fungicide (captan) and a soil fumigant (metham sodium). By applying existing models, a prediction is presented of post-treatment dispersal and deposit...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: de Jong FM,van der Voet E,Canters KJ

    更新日期:1995-02-01 00:00:00

  • Sediment genotoxicity in the Tietê River (São Paulo, Brazil): in vitro comet assay versus in situ micronucleus assay studies.

    abstract::The in vitro comet assay with the permanent fish cell line RTL-W1 and the in situ micronucleus assay using erythrocytes from indigenous tilapia (Oreochromis niloticus) were used to detect genotoxicity in Tietê River sediments (São Paulo, Brazil). Either test was successful in identifying site-specific differences in g...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章


    authors: Rocha PS,Luvizotto GL,Kosmehl T,Böttcher M,Storch V,Braunbeck T,Hollert H

    更新日期:2009-10-01 00:00:00