Observability of Boolean multiplex control networks.

Abstract:

:Boolean multiplex (multilevel) networks (BMNs) are currently receiving considerable attention as theoretical arguments for modeling of biological systems and system level analysis. Studying control-related problems in BMNs may not only provide new views into the intrinsic control in complex biological systems, but also enable us to develop a method for manipulating biological systems using exogenous inputs. In this article, the observability of the Boolean multiplex control networks (BMCNs) are studied. First, the dynamical model and structure of BMCNs with control inputs and outputs are constructed. By using of Semi-Tensor Product (STP) approach, the logical dynamics of BMCNs is converted into an equivalent algebraic representation. Then, the observability of the BMCNs with two different kinds of control inputs is investigated by giving necessary and sufficient conditions. Finally, examples are given to illustrate the efficiency of the obtained theoretical results.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Wu Y,Xu J,Sun XM,Wang W

doi

10.1038/srep46495

subject

Has Abstract

pub_date

2017-04-28 00:00:00

pages

46495

issn

2045-2322

pii

srep46495

journal_volume

7

pub_type

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