Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health.

abstract：BACKGROUND:Helicobacter pylori forms biofilms on glass surfaces at the air-liquid interface in in vitro batch cultures; however, biofilms of H. pylori have not been well characterized. In the present study, we analyzed the ability of H. pylori strains to form biofilms and characterized the underlying mechanisms of H. p...

journal_title：BMC microbiology

authors： Yonezawa H,Osaki T,Kurata S,Fukuda M,Kawakami H,Ochiai K,Hanawa T,Kamiya S

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:Enterohemorrhagic Escherichia coli (EHEC) colonizes the intestinal epithelium and causes attaching and effacing (A/E) lesions. Expression of virulence genes, particularly those from the locus of the enterocyte effacement (LEE) pathogenicity island is required for the formation of a type three secretion syste...

journal_title：BMC microbiology

authors： Hansen AM,Jin DJ

更新日期：2012-10-11 00:00:00

abstract：BACKGROUND:In this study, we have evaluated the immunological status of hepatitis C virus (HCV)-infected patients aiming at identifying putative biomarkers associated with distinct degrees of liver fibrosis. Peripheral blood and tissue T-cells as well as cytokine levels were quantified by flow cytometry. RESULTS:Data ...

journal_title：BMC microbiology

authors： de Souza-Cruz S,Victória MB,Tarragô AM,da Costa AG,Pimentel JP,Pires EF,Araújo Lde P,Coelho-dos-Reis JG,Gomes Mde S,Amaral LR,Teixeira-Carvalho A,Martins-Filho OA,Victória Fda S,Malheiro A

更新日期：2016-01-07 00:00:00

abstract：BACKGROUND:Changes in aboveground plant species diversity as well as variations of environmental conditions such as exposure of ecosystems to elevated concentrations of atmospheric carbon dioxide may lead to changes in metabolic activity, composition and diversity of belowground microbial communities, both bacterial an...

journal_title：BMC microbiology

authors： Grüter D,Schmid B,Brandl H

更新日期：2006-07-27 00:00:00

abstract：BACKGROUND:The balanced synthesis of membrane phospholipids, fatty acids and cell wall constituents is a vital facet of bacterial physiology, but there is little known about the biochemical control points that coordinate these activities in Gram-positive bacteria. In Escherichia coli, the glycerol-phosphate acyltransfe...

journal_title：BMC microbiology

authors： Parsons JB,Yao J,Jackson P,Frank M,Rock CO

更新日期：2013-11-16 00:00:00

abstract：BACKGROUND:The resurgence of multi-drug resistant tuberculosis (MDR-TB) and HIV associated tuberculosis (TB) are of serious global concern. To contain this situation, new anti-tuberculosis drugs and reduced treatment regimens are imperative. Recently, a nitroimidazole, PA-824, has been shown to be active against both r...

journal_title：BMC microbiology

authors： Somasundaram S,Anand RS,Venkatesan P,Paramasivan CN

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The lung of patients with cystic fibrosis (CF) is particularly sensitive to Pseudomonas aeruginosa. This bacterium plays an important role in the poor outcome of CF patients. During the disease progress, first acquisition of P. aeruginosa is the key-step in the management of CF patients. Quantitative PCR (qP...

journal_title：BMC microbiology

authors： Le Gall F,Le Berre R,Rosec S,Hardy J,Gouriou S,Boisramé-Gastrin S,Vallet S,Rault G,Payan C,Héry-Arnaud G

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Helicobacter pylori has diverged in parallel to its human host, leading to distinct phylogeographic populations. Recent evidence suggests that in the current human mixing in Latin America, European H. pylori (hpEurope) are increasingly dominant at the expense of Amerindian haplotypes (hspAmerind). This pheno...

journal_title：BMC microbiology

authors： Maldonado-Contreras A,Mane SP,Zhang XS,Pericchi L,Alarcón T,Contreras M,Linz B,Blaser MJ,Domínguez-Bello MG

更新日期：2013-09-19 00:00:00

abstract：BACKGROUND:Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously reported that S. aureus strain P1 encodes an FnBPA protein where the fibrinogen/elastin-binding domain (A domain) is substantially divergent in amino acid sequence from the a...

journal_title：BMC microbiology

authors： Loughman A,Sweeney T,Keane FM,Pietrocola G,Speziale P,Foster TJ

更新日期：2008-05-08 00:00:00

abstract：BACKGROUND:Several intracellular bacterial pathogens have evolved subtle strategies to subvert vesicular trafficking pathways of their host cells to avoid killing and to replicate inside the cells. Brucellae are Gram-negative facultative intracellular bacteria that are responsible for brucellosis, a worldwide extended ...

journal_title：BMC microbiology

authors： Hamer I,Goffin E,De Bolle X,Letesson JJ,Jadot M

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. However, the clinical c...

journal_title：BMC microbiology

authors： Zhang D,Dong P,Zhang K,Deng L,Bach C,Chen W,Li F,Protzer U,Ding H,Zeng C

更新日期：2012-12-28 00:00:00

abstract：BACKGROUND:Alpha-isopropylmalate synthase (alpha-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding alpha-IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repea...

journal_title：BMC microbiology

authors： Yindeeyoungyeon W,Likitvivatanavong S,Palittapongarnpim P

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Lactic acid bacteria (LAB) has been considered a beneficial bacterial group, found as part of the microbiota of diverse hosts, including humans and various animals. However, the mechanisms of how hosts and LAB interact are still poorly understood. Previous work demonstrates that 13 species of Lactobacillus a...

journal_title：BMC microbiology

authors： Butler È,Alsterfjord M,Olofsson TC,Karlsson C,Malmström J,Vásquez A

更新日期：2013-10-22 00:00:00

abstract：BACKGROUND:Several plant-pathogenic bacteria are transmitted by insect vector species that often also act as hosts. In this interface, these bacteria encounter plant endophytic, insect endosymbiotic and other microbes. Here, we used high throughput sequencing to examine the bacterial communities of five different psyll...

journal_title：BMC microbiology

authors： Morrow JL,Om N,Beattie GAC,Chambers GA,Donovan NJ,Liefting LW,Riegler M,Holford P

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Salmonella enterica is a causative agent of foodborne gastroenteritis and the systemic disease known as typhoid fever. This bacterium uses two type three secretion systems (T3SSs) to translocate protein effectors into host cells to manipulate cellular function. Salmonella pathogenicity island (SPI)-2 encodes...

journal_title：BMC microbiology

authors： Cooper CA,Mulder DT,Allison SE,Pilar AV,Coombes BK

更新日期：2013-10-04 00:00:00

abstract：BACKGROUND:Globally, staphylococci have developed resistance to many antibiotics. New approaches to chemotherapy are needed and one such approach could be to use plant derived actives with conventional antibiotics in a synergestic way. The purpose of this study was to isolate α-mangostin from the mangosteen (Garcinia m...

journal_title：BMC microbiology

authors： Phitaktim S,Chomnawang M,Sirichaiwetchakoon K,Dunkhunthod B,Hobbs G,Eumkeb G

更新日期：2016-08-26 00:00:00

abstract：BACKGROUND:Antimicrobial helper-compounds may reverse antimicrobial resistance. Sertraline, a antidepressant drug, has been suggested as a tetracycline helper-compound. Tetracycline is the preferred antimicrobial for treatment of enteric diseases in pigs. This study is the first to evaluate the potency of sertraline as...

journal_title：BMC microbiology

authors： Kromann S,Hvidtfeldt A,Boye M,Sørensen DB,Jørgensen S,Nielsen JP,Olsen RH

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Legionella pneumophila, the causative agent of Legionnaire's disease, may enter a viable but non-culturable (VBNC) state triggered by environmental stress conditions. Specific outer-membrane epitopes of L. pneumophila are used in many diagnostic applications and some of them are linked to important virulence...

journal_title：BMC microbiology

authors： Schrammel B,Petzold M,Cervero-Aragó S,Sommer R,Lück C,Kirschner A

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND:Mannheimia haemolytica strains isolated from North American cattle have been classified into two genotypes (1 and 2). Although members of both genotypes have been isolated from the upper and lower respiratory tracts of cattle with or without bovine respiratory disease (BRD), genotype 2 strains are much more ...

journal_title：BMC microbiology

authors： Clawson ML,Schuller G,Dickey AM,Bono JL,Murray RW,Sweeney MT,Apley MD,DeDonder KD,Capik SF,Larson RL,Lubbers BV,White BJ,Blom J,Chitko-McKown CG,Brichta-Harhay DM,Smith TPL

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:There is an increasing interest to better understand endosymbiont capabilities in insects both from an ecological point of view and for pest control. Blochmannia floridanus provides important nutrients for its host, the ant Camponotus, while the bacterium in return is provided with a niche to proliferate. Bl...

journal_title：BMC microbiology

authors： Gaudermann P,Vogl I,Zientz E,Silva FJ,Moya A,Gross R,Dandekar T

更新日期：2006-01-09 00:00:00

abstract：BACKGROUND:Abundant populations of bacteria have been observed on Mir and the International Space Station. While some experiments have shown that bacteria cultured during spaceflight exhibit a range of potentially troublesome characteristics, including increases in growth, antibiotic resistance and virulence, other stu...

journal_title：BMC microbiology

authors： Kim W,Tengra FK,Shong J,Marchand N,Chan HK,Young Z,Pangule RC,Parra M,Dordick JS,Plawsky JL,Collins CH

更新日期：2013-11-06 00:00:00

abstract：BACKGROUND:Growing concerns about bacterial resistance to antibiotics have prompted the development of alternative therapies like those based on cationic antimicrobial peptides (APs). These compounds not only are bactericidal by themselves but also enhance the activity of antibiotics. Studies focused on the systematic ...

journal_title：BMC microbiology

authors： Sánchez-Gómez S,Lamata M,Leiva J,Blondelle SE,Jerala R,Andrä J,Brandenburg K,Lohner K,Moriyón I,Martínez-de-Tejada G

更新日期：2008-11-11 00:00:00

abstract：BACKGROUND:Viability staining with SYTO9 and propidium iodide (PI) is a frequently used tool in microbiological studies. However, data generated by such routinely used method are often not critically evaluated for their accuracy. In this study we aim to investigate the critical aspects of this staining method using Sta...

journal_title：BMC microbiology

authors： Stiefel P,Schmidt-Emrich S,Maniura-Weber K,Ren Q

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:Cathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors - cystatins. Cathepsins are crucial to antigen processing during viral and bacterial infections, and as such are a prerequisite to antige...

journal_title：BMC microbiology

authors： Bossowska-Nowicka M,Mielcarska MB,Romaniewicz M,Kaczmarek MM,Gregorczyk-Zboroch KP,Struzik J,Grodzik M,Gieryńska MM,Toka FN,Szulc-Dąbrowska L

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Staphylococcus aureus methicillin-resistant (MRSA) has been frequently isolated from endotracheal and lung puncture aspirates in malnourished children with pneumonia. In this work we evaluated the susceptibility of undernourished BALB/c mice and its ability to mount a protective immunity against MRSA with em...

journal_title：BMC microbiology

authors： França TG,Ishikawa LL,Zorzella-Pezavento SF,Chiuso-Minicucci F,Guerino CP,da Cunha Mde L,Sartori A

更新日期：2009-11-23 00:00:00

abstract：BACKGROUND:The Gram-negative bacterium Erwinia amylovora is the causal agent of the devastating disease fire blight in rosaceous plants such as apple, pear, quince, raspberry, and cotoneaster. In order to survive and multiply in a host, microbes must be able to circumvent the toxic effects of antimicrobial plant compou...

journal_title：BMC microbiology

authors： Pletzer D,Weingart H

更新日期：2014-07-11 00:00:00

abstract：BACKGROUND:Identification and characterization of intervening sequences (IVSs) within 23S rRNA genes from Campylobacter organisms including atypical campylobacters were carried out using two PCR primer pairs, designed to generate helix 25 and 45 regions. RESULTS:Only C. sputorum biovar sputorum LMG7975 and fecalis LMG...

journal_title：BMC microbiology

authors： Tazumi A,Kakinuma Y,Misawa N,Moore JE,Millar BC,Matsuda M

更新日期：2009-12-11 00:00:00

abstract：BACKGROUND:Microbial fuel cells (MFCs) are devices that exploit microorganisms to generate electric power from organic matter. Despite the development of efficient MFC reactors, the microbiology of electricity generation remains to be sufficiently understood. RESULTS:A laboratory-scale two-chamber microbial fuel cell ...

journal_title：BMC microbiology

authors： Ishii S,Shimoyama T,Hotta Y,Watanabe K

更新日期：2008-01-10 00:00:00

abstract：BACKGROUND:After E. coli O157, E. coli O26 is the second most prevalent enterohaemorrhagic E. coli (EHEC) serotype identified in cases of foodborne illness in Australia and throughout the world. E. coli O26 associated foodborne outbreaks have drawn attention to the survival capabilities of this organism in a range of e...

journal_title：BMC microbiology

authors： Lajhar SA,Brownlie J,Barlow R

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Mycobacterium abscessus group includes antibiotic-resistant, opportunistic mycobacteria that are responsible for sporadic cases and outbreaks of cutaneous, pulmonary and disseminated infections. However, because of their close genetic relationships, accurate discrimination between the various strains of thes...

journal_title：BMC microbiology

authors： Sassi M,Ben Kahla I,Drancourt M

更新日期：2013-01-07 00:00:00