Normobaric hypoxia increases the growth hormone response to maximal resistance exercise in trained men.

Abstract:

:This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82 ± 2%) and normoxia (NOR; FiO2 0.21, SpO2 98 ± 0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum. Heart rate, SpO2, and electromyographic activity (EMG) of the vastus lateralis muscle were measured throughout the protocol. Serum lactate and GH levels were determined pre-exposure, and at 5, 15, 30 and 60 min post-exercise. Differences in mean and integrated EMG between HYP and NOR treatments were unclear. However, there was an important increase in the peak levels and area under the curve of both lactate (HYP 5.8 ± 1.8 v NOR 3.9 ± 1.1 mmol.L-1 and HYP 138.7 ± 33.1 v NOR 105.8 ± 20.8 min.mmol.L-1) and GH (HYP 4.4 ± 3.1 v NOR 2.1 ± 2.5 ng.mL-1 and HYP 117.7 ± 86.9 v NOR 72.9 ± 85.3 min.ng.mL-1) in response to HYP. These results suggest that performing high-intensity resistance exercise in a hypoxic environment may provide a beneficial endocrine response without compromising the neuromuscular activation required for maximal strength development.

journal_name

Eur J Sport Sci

authors

Filopoulos D,Cormack SJ,Whyte DG

doi

10.1080/17461391.2017.1317834

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

821-829

issue

7

eissn

1746-1391

issn

1536-7290

journal_volume

17

pub_type

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