Stereotactic body radiotherapy for pediatric hepatocellular carcinoma with central biliary obstruction.

abstract：BACKGROUND:The purpose of our study was to assess long-term cause-specific mortality of 5-year childhood cancer survivors. PROCEDURE:The study population consisted of 1,378 patients who had been treated for childhood cancer in The Netherlands between 1966 and 1996 and survived at least 5 years; follow-up was complete ...

journal_title：Pediatric blood & cancer

authors： Cardous-Ubbink MC,Heinen RC,Langeveld NE,Bakker PJ,Voûte PA,Caron HN,van Leeuwen FE

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Parents and physicians may have different understandings of a child's risk of future limitations due to cancer or cancer treatment. We evaluated alignment between parent- and physician-estimated risk of late effects. METHODS:We surveyed 352 parents of children with cancer within 12 weeks of diagnosis, and t...

journal_title：Pediatric blood & cancer

authors： Greenzang KA,Cronin AM,Kang T,Mack JW

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Melanoma is a common cancer among adolescents and young adults (AYAs), yet adherence to recommended surveillance and factors related to adherence are not well understood in this population. This study assessed the prevalence and correlates of physician-conducted skin examination (PSE) and skin self-examinati...

journal_title：Pediatric blood & cancer

authors： Miller KA,Wojcik KY,Cockburn MG,In GK,Hamilton AS,Milam JE

更新日期：2020-03-01 00:00:00

abstract：:As increasing numbers of childhood cancer patients are surviving, the long-term complications of the disease and its treatment have become ever more increasingly important. Reduced bone mineral density and increased fracture risk have been reported during and after treatment of children with cancer. The causes of oste...

journal_title：Pediatric blood & cancer

authors： van der Sluis IM,van den Heuvel-Eibrink MM

更新日期：2008-02-01 00:00:00

abstract：:We report three cases of hemophagocytic lymphohistiocytosis (HLH) in infants within the first 6 weeks of life. Diagnosis of HLH was made early after symptoms started. All three cases were successfully treated with dexamethasone and none relapsed, indicating that not all cases of HLH in very young infants are familial....

journal_title：Pediatric blood & cancer

authors： Tanoshima R,Takahashi H,Hokosaki T,Yamaguchi K,Goto S,Kai S

更新日期：2009-01-01 00:00:00

abstract：:Social media are powerful means of communication that can also have an important role in the healthcare sector. They are sometimes seen with diffidence in the healthcare setting, partly because they risk blurring professional boundaries. This issue is particularly relevant to relations between caregivers and adolescen...

journal_title：Pediatric blood & cancer

authors： Clerici CA,Quarello P,Bergadano A,Veneroni L,Bertolotti M,Guadagna P,Ricci A,Galdi A,Fagioli F,Ferrari A

更新日期：2018-05-01 00:00:00

abstract：:Hemophagocytic lymphohistioytosis (HLH) is a severe, life-threatening hyperinflammatory disorder that requires prompt diagnosis and treatment. Approximately, 25-50% of patients with HLH fail to achieve remission with established regimens that include dexamethasone and etoposide, or methylprednisolone and antithymocyte...

journal_title：Pediatric blood & cancer

authors： Marsh RA,Jordan MB,Talano JA,Nichols KE,Kumar A,Naqvi A,Vaiselbuh SR,Histiocyte Society Salvage Therapy Working Group.

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The aims of this study were to define the mRNA expression profiles of MYCN, DDX1, TrkA, and TrkC in biopsy tumor samples from 64 Brazilian patients with neuroblastomas of different risk stages and to correlate altered expression with prognostic values. PROCEDURE:Patients were retrospectively classified into...

journal_title：Pediatric blood & cancer

authors： de Souza DR,Sanabani SS,de Souza AC,Filho Odone V,Epelman S,Bendit I

更新日期：2011-05-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is a rare disease in children. Different from that in adults, childhood CML involves transformative events occurring over a short time period. CML transformation to lymphoid blast phase (BP) is associated with copy number abnormalities, characteristic of BCR-ABL1 positive acute lymphobla...

journal_title：Pediatric blood & cancer

authors： Klumb CE,Barbosa TDC,Nestal de Moraes G,Schramm MT,Emerenciano M,Maia RC

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Malignant ectomesenchymoma (MEM) is a soft tissue tumor with heterologous rhabdomyoblastic components believed to arise from pluripotent migratory neural crest cells. To date merely 50 cases have been published and the knowledge about the course of disease and optimal treatment is limited. METHODS:Six patie...

journal_title：Pediatric blood & cancer

authors： Dantonello TM,Leuschner I,Vokuhl C,Gfroerer S,Schuck A,Kube S,Nathrath M,Bernbeck B,Kaatsch P,Pal N,Ljungman G,Bielack SS,Klingebiel T,Koscielniak E,CWS.

更新日期：2013-02-01 00:00:00

abstract：:Although investigators have been engaged in the study of human energy metabolism for over 100 years, there remain unanswered questions regarding the role that energy expenditure plays in human health and disease. A critical examination of available methods for measurement of the various components of daily energy expe...

journal_title：Pediatric blood & cancer

authors： DeLany JP

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Complications in pediatric cancer patients after a gastrostomy (GT) placement have not been widely investigated. We aimed to evaluate the complication rate and nature of complications in this specific population. PROCEDURE:Medical records of pediatric cancer patients having a GT placed at our institution fr...

journal_title：Pediatric blood & cancer

authors： Fernandez-Pineda I,Sandoval JA,Jones RM,Boateng N,Wu J,Rao BN,Davidoff AM,Shochat SJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:A feature often seen in adolescent patients with cancer is a lengthy symptom interval, especially in comparison with children. It has been suggested that inadequate awareness of cancer risk among adolescents may play an important role in this study. METHODS:The Società Italiana Adolescenti con Malattie Onco...

journal_title：Pediatric blood & cancer

authors： Magni C,Segrè C,Finzi C,Veneroni L,Clerici CA,Massimino M,Casanova M,Martinella V,Chiaravalli S,Ricci A,Biondi A,Ferrari A

更新日期：2016-08-01 00:00:00

abstract：:High dose acetaminophen (HDAC) with N-acetylcysteine (NAC) has been effective in adults with advanced malignancies. We report HDAC with NAC in a child with progressive hepatoblastoma, confirmed at biopsy of an unresectable hepatic mass. Alpha-fetoprotein (AFP) increased despite four courses of doxorubicin and one cour...

journal_title：Pediatric blood & cancer

authors： Kobrinsky NL,Sjolander DE,Goldenberg JA,Ortmeier TC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:The Paediatric Oncology Centres (POCs) treating childhood cancer in South East England produce unified supportive care guidelines for use in the secondary pediatric (shared care) units. This study evaluated the adherence to current guidelines for febrile neutropenia (FN) and documented outcome in terms of ba...

journal_title：Pediatric blood & cancer

authors： Duncan C,Chisholm JC,Freeman S,Riley U,Sharland M,Pritchard-Jones K

更新日期：2007-10-15 00:00:00

abstract：:Adolescents and young adults (AYA) with acute lymphoblastic leukaemia (ALL) constitute a distinct population from children and older adults. Based on patterns of referral, they may be treated by either paediatric or adult oncologists. As a group, AYA with ALL have a worse survival and event-free survival (EFS) compare...

journal_title：Pediatric blood & cancer

authors： Ramanujachar R,Richards S,Hann I,Webb D

更新日期：2006-11-01 00:00:00

abstract：:The youngest siblings may be both emotionally vulnerable and often neglected members of the family of a childhood cancer patient. The prompt identification of signs of distress in these subjects allows trained caregivers to intervene with personalized, age-appropriate, attention, and care. A narrative approach, based ...

journal_title：Pediatric blood & cancer

authors： Massimo LM,Wiley TJ

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Children with hepatoblastoma (HB) are at risk of sarcopenia due to immobility, chemotherapy, and malnutrition. We hypothesized that children with HB have a low preoperative total psoas muscle area (tPMA), reflecting sarcopenia, which negatively impacts outcome. PROCEDURE:Retrospective study of children (1-1...

journal_title：Pediatric blood & cancer

authors： Ritz A,Kolorz J,Hubertus J,Ley-Zaporozhan J,von Schweinitz D,Koletzko S,Häberle B,Schmid I,Kappler R,Berger M,Lurz E

更新日期：2021-01-12 00:00:00

abstract：:Although limited data are available about cyclophosphamide disposition in patients with renal insufficiency, nothing has been reported in anephric patients. We characterized cyclophosphamide pharmacokinetics in an anephric child with bilateral Wilms tumor, both on (day 1) and off (day 2) hemodialysis. The median cyclo...

journal_title：Pediatric blood & cancer

authors： McCune JS,Adams D,Homans AC,Guillot A,Iacono L,Stewart CF

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Image-guided percutaneous core needle biopsy (PCNB) is increasingly utilized to diagnose solid tumors. The objective of this study is to determine whether PCNB is adequate for modern biologic characterization of neuroblastoma. PROCEDURE:A multi-institutional retrospective study was performed by the Pediatri...

journal_title：Pediatric blood & cancer

authors： Overman RE,Kartal TT,Cunningham AJ,Fialkowski EA,Naik-Mathuria BJ,Vasudevan SA,Malek MM,Kalsi R,Le HD,Stafford LC,Lautz TB,Many BT,Jones RE,Bütter A,Davidson J,Williams A,Dasgupta R,Lewis J,Troutt M,Aldrink JH,Man

更新日期：2020-05-01 00:00:00

abstract：:Hepatoblastoma (HB) and biliary atresia (BA) are both rare conditions that occurred in the patient described. This is the second such case in the literature. An explanation for this apparent coincidence could possibly be found in the existance of pluripotent liver stem cells. In humans, small epithelial cells (SEC) be...

journal_title：Pediatric blood & cancer

authors： Taat F,Bosman DK,Aronson DC

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Progressive/recurrent high-grade and diffuse intrinsic pontine gliomas (DIPGs) are fatal. Treatments targeting molecular pathways critical for these cancers are needed. METHODS:We conducted a phase 1 study (rolling-six design) to establish the safety and maximum tolerated dose (MTD) of dasatinib, an oral pl...

journal_title：Pediatric blood & cancer

authors： Broniscer A,Jia S,Mandrell B,Hamideh D,Huang J,Onar-Thomas A,Gajjar A,Raimondi SC,Tatevossian RG,Stewart CF

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Pegasparaginase (PEG) is important for treatment of Acute Lymphoblastic Leukemia (ALL). Despite conjugation to polyethylene glycol to reduce immunogenicity, allergic reactions still occur and may be severe. Traditionally, PEG is given via intramuscular (IM) injection but recent protocols have shown it can be...

journal_title：Pediatric blood & cancer

authors： Pidaparti M,Bostrom B

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Specialized pediatric cancer centers (PCCs) are thought to be essential to obtain state-of-the-art care for children and adolescents. We determined the proportion of childhood cancer patients not treated in a PCC, and described their characteristics and place of treatment. PROCEDURE:The Swiss Childhood Canc...

journal_title：Pediatric blood & cancer

authors： Adam M,von der Weid N,Michel G,Zwahlen M,Lutz JM,Probst-Hensch N,Niggli F,Kuehni C,Swiss Pediatric Oncology Group (SPOG).,Swiss Association of Cancer Registries (ASRT).

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Patients with sickle cell disease (SCD) receiving chronic blood transfusions are at risk of developing iron overload and organ toxicity. Chelation therapy with either subcutaneous (SQ) desferrioxamine (DFO) or oral deferasirox is effective in preventing and reducing iron overload but poses significant challe...

journal_title：Pediatric blood & cancer

authors： Kalpatthi R,Peters B,Kane I,Holloman D,Rackoff E,Disco D,Jackson S,Laver JH,Abboud MR

更新日期：2010-12-15 00:00:00

abstract：:Data on prognostic factors in pelvic PNET are minimal. We analyzed patients with pelvic PNET treated between June 2003 and November 2011 for prognostic factors. Forty-eight (13%) of 374 patients with PNET were pelvic PNET with median age 14.5 years (range: 5-33); 31 (65%) had metastases. After median follow-up of 20.4...

journal_title：Pediatric blood & cancer

authors： Biswas B,Agarwala S,Rastogi S,Khan SA,Mohanti BK,Sharma DN,Pathy S,Bakhshi S

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:We sought to determine the risk of bacteremia in a cohort of outpatient febrile nonneutropenic pediatric oncology patients and to assess clinical characteristics that may influence decisions regarding empiric antibiotic therapy. PROCEDURE:A single institution retrospective cohort study was performed of outp...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Vivier PM,Panken TM,Schwartz CL

更新日期：2010-01-01 00:00:00

abstract：:The Standards, Options, and Recommendations (SOR) project undertaken by the French National Federation of Cancer Centers (FNCLCC) to develop and disseminate clinical practice guidelines in oncology has now been taken over by the French National Cancer Institute. In 2007, the SOR updated the information related to the ...

journal_title：Pediatric blood & cancer

authors： Marec-Berard P,Chastagner P,Kassab-Chahmi D,Casadevall N,Marchal C,Misset JL,Ray-Coquard I

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Children with sickle cell disease (SCD) and abnormal transcranial Doppler (TCD) ultrasonography have a high risk of stroke, but this risk is greatly reduced when chronic transfusion therapy is administered. The change in TCD velocities during chronic transfusion therapy and rate and frequency of normalizatio...

journal_title：Pediatric blood & cancer

authors： Kwiatkowski JL,Yim E,Miller S,Adams RJ,STOP 2 Study Investigators.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Bleomycin is associated with pulmonary toxic side effects including pneumonitis and pulmonary fibrosis. We evaluated the prevalence of long-term pulmonary function abnormalities in children receiving bleomycin therapy in the context of current chemotherapeutic regimens. METHODS:A retrospective review of pat...

journal_title：Pediatric blood & cancer

authors： De A,Guryev I,LaRiviere A,Kato R,Wee CP,Mascarenhas L,Keens TG,Venkatramani R

更新日期：2014-09-01 00:00:00