Single-subject independent component analysis-based intensity normalization in non-quantitative multi-modal structural MRI.

Abstract:

:Non-quantitative MRI is prone to intersubject intensity variation rendering signal intensity level based analyses limited. Here, we propose a method that fuses non-quantitative routine T1-weighted (T1w), T2w, and T2w fluid-saturated inversion recovery sequences using independent component analysis and validate it on age and sex matched healthy controls. The proposed method leads to consistent and independent components with a significantly reduced coefficient-of-variation across subjects, suggesting potential to serve as automatic intensity normalization and thus to enhance the power of intensity based statistical analyses. To exemplify this, we show that voxelwise statistical testing on single-subject independent components reveals in particular a widespread sex difference in white matter, which was previously shown using, for example, diffusion tensor imaging but unobservable in the native MRI contrasts. In conclusion, our study shows that single-subject independent component analysis can be applied to routine sequences, thereby enhancing comparability in-between subjects. Unlike quantitative MRI, which requires specific sequences during acquisition, our method is applicable to existing MRI data. Hum Brain Mapp 38:3615-3622, 2017. © 2017 Wiley Periodicals, Inc.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Papazoglou S,Würfel J,Paul F,Brandt AU,Scheel M

doi

10.1002/hbm.23615

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

3615-3622

issue

7

eissn

1065-9471

issn

1097-0193

journal_volume

38

pub_type

杂志文章
  • In vivo delineation of subdivisions of the human amygdaloid complex in a high-resolution group template.

    abstract::The nuclei of the human amygdala remain difficult to distinguish in individual subject structural magnetic resonance images. However, interpretation of the amygdala's role in whole brain networks requires accurate localization of functional activity to a particular nucleus or subgroup of nuclei. To address this, high ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23289

    authors: Tyszka JM,Pauli WM

    更新日期:2016-11-01 00:00:00

  • Characterizing hippocampal dynamics with MEG: A systematic review and evidence-based guidelines.

    abstract::The hippocampus, a hub of activity for a variety of important cognitive processes, is a target of increasing interest for researchers and clinicians. Magnetoencephalography (MEG) is an attractive technique for imaging spectro-temporal aspects of function, for example, neural oscillations and network timing, especially...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24445

    authors: Ruzich E,Crespo-García M,Dalal SS,Schneiderman JF

    更新日期:2019-03-01 00:00:00

  • Prediction of human actions: expertise and task-related effects on neural activation of the action observation network.

    abstract::The action observation network (AON) is supposed to play a crucial role when athletes anticipate the effect of others' actions in sports such as tennis. We used functional magnetic resonance imaging to explore whether motor expertise leads to a differential activation pattern within the AON during effect anticipation ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22455

    authors: Balser N,Lorey B,Pilgramm S,Stark R,Bischoff M,Zentgraf K,Williams AM,Munzert J

    更新日期:2014-08-01 00:00:00

  • Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis.

    abstract::Huntington disease (HD) is a neurodegenerative disorder that involves preferential atrophy in the striatal complex and related subcortical nuclei. In this article, which is based on a dataset extracted from the PREDICT-HD study, we use statistical shape analysis with deformation markers obtained through "Large Deforma...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22214

    authors: Younes L,Ratnanather JT,Brown T,Aylward E,Nopoulos P,Johnson H,Magnotta VA,Paulsen JS,Margolis RL,Albin RL,Miller MI,Ross CA,PREDICT-HD Investigators and Coordinators of the Huntington Study Group.

    更新日期:2014-03-01 00:00:00

  • Accessing orthographic representations from speech: the role of left ventral occipitotemporal cortex in spelling.

    abstract::The present fMRI study used a spelling task to investigate the hypothesis that the left ventral occipitotemporal cortex (vOT) hosts neuronal representations of whole written words. Such an orthographic word lexicon is posited by cognitive dual-route theories of reading and spelling. In the scanner, participants perfor...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22709

    authors: Ludersdorfer P,Kronbichler M,Wimmer H

    更新日期:2015-04-01 00:00:00

  • Volumetric and shape analysis of the thalamus in first-episode schizophrenia.

    abstract::Thalamic abnormalities have been implicated in the pathogenesis of schizophrenia, although the majority of studies used chronic samples treated extensively with antipsychotics. Moreover, the clinical and neuropsychological correlates of these abnormalities remain largely unknown. Using high-resolution MR imaging and n...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20595

    authors: Coscia DM,Narr KL,Robinson DG,Hamilton LS,Sevy S,Burdick KE,Gunduz-Bruce H,McCormack J,Bilder RM,Szeszko PR

    更新日期:2009-04-01 00:00:00

  • Cortical localization of phase and amplitude dynamics predicting access to somatosensory awareness.

    abstract::Neural dynamics leading to conscious sensory perception have remained enigmatic in despite of large interest. Human functional magnetic resonance imaging (fMRI) studies have revealed that a co-activation of sensory and frontoparietal areas is crucial for conscious sensory perception in the several second time-scale of...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23033

    authors: Hirvonen J,Palva S

    更新日期:2016-01-01 00:00:00

  • Spatial orienting in complex audiovisual environments.

    abstract::Previous studies on crossmodal spatial orienting typically used simple and stereotyped stimuli in the absence of any meaningful context. This study combined computational models, behavioural measures and functional magnetic resonance imaging to investigate audiovisual spatial interactions in naturalistic settings. We ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22276

    authors: Nardo D,Santangelo V,Macaluso E

    更新日期:2014-04-01 00:00:00

  • Modular preprocessing pipelines can reintroduce artifacts into fMRI data.

    abstract::The preprocessing pipelines typically used in both task and resting-state functional magnetic resonance imaging (rs-fMRI) analysis are modular in nature: They are composed of a number of separate filtering/regression steps, including removal of head motion covariates and band-pass filtering, performed sequentially and...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24528

    authors: Lindquist MA,Geuter S,Wager TD,Caffo BS

    更新日期:2019-06-01 00:00:00

  • Event-related potential and functional MRI measures of face-selectivity are highly correlated: a simultaneous ERP-fMRI investigation.

    abstract::A face-selective neural signal is reliably found in humans with functional MRI and event-related potential (ERP) measures, which provide complementary information about the spatial and temporal properties of the neural response. However, because most neuroimaging studies so far have studied ERP and fMRI face-selective...

    journal_title:Human brain mapping

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/hbm.20952

    authors: Sadeh B,Podlipsky I,Zhdanov A,Yovel G

    更新日期:2010-10-01 00:00:00

  • Network abnormalities among non-manifesting Parkinson disease related LRRK2 mutation carriers.

    abstract::Non-manifesting carriers (NMC) of the G2019S mutation in the LRRK2 gene represent an "at risk" group for future development of Parkinson's disease (PD) and have demonstrated task related fMRI changes. However, resting-state networks have received less research focus, thus this study aimed to assess the integrity of th...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24543

    authors: Jacob Y,Rosenberg-Katz K,Gurevich T,Helmich RC,Bloem BR,Orr-Urtreger A,Giladi N,Mirelman A,Hendler T,Thaler A

    更新日期:2019-06-01 00:00:00

  • A Comparison of the neural correlates that underlie rule-based and information-integration category learning.

    abstract::The influential competition between verbal and implicit systems (COVIS) model proposes that category learning is driven by two competing neural systems-an explicit, verbal, system, and a procedural-based, implicit, system. In the current fMRI study, participants learned either a conjunctive, rule-based (RB), category ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23259

    authors: Carpenter KL,Wills AJ,Benattayallah A,Milton F

    更新日期:2016-10-01 00:00:00

  • Task-related modulation of functional connectivity variability and its behavioral correlations.

    abstract::Two new directions of functional connectivity investigation are emerging to advance studies of the brain's functional organization. First, the identification of task-related dynamics of functional connectivity has elicited a growing interest in characterizing the brain's functional reorganization due to task demands. ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22847

    authors: Elton A,Gao W

    更新日期:2015-08-01 00:00:00

  • Functional cerebral asymmetry analyses reveal how the control system implements its flexibility.

    abstract::The control system in human brain generally exerts the goal-directed regulation on a variety of mental processes. To deal with different control demands, these brain areas of the control system, especially the dorsolateral prefrontal cortex (DLPFC), may be flexibly recruited across different tasks. However, few studie...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24313

    authors: Chen Z,Zhao X,Fan J,Chen A

    更新日期:2018-12-01 00:00:00

  • Topographical relationships between arcuate fasciculus connectivity and cortical thickness.

    abstract::The arcuate fasciculus (AF) connects cortical regions important in language processing, but how fiber coherence and organization relates to gray matter macrostructure remains uncharacterized. We used high-resolution structural and 30-direction diffusion imaging data from 36 healthy adults (24 male/12 female; mean age,...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21147

    authors: Phillips OR,Clark KA,Woods RP,Subotnik KL,Asarnow RF,Nuechterlein KH,Toga AW,Narr KL

    更新日期:2011-11-01 00:00:00

  • Do intrinsic brain functional networks predict working memory from childhood to adulthood?

    abstract::Working memory (WM) is defined as the ability to maintain a representation online to guide goal-directed behavior. Its capacity in early childhood predicts academic achievements in late childhood and its deficits are found in various neurodevelopmental disorders. We employed resting-state fMRI (rs-fMRI) of 468 partici...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25143

    authors: Zhang H,Hao S,Lee A,Eickhoff SB,Pecheva D,Cai S,Meaney M,Chong YS,Broekman BFP,Fortier MV,Qiu A

    更新日期:2020-11-01 00:00:00

  • Functional connectivity-based parcellation of amygdala using self-organized mapping: a data driven approach.

    abstract::The overall goal of this work is to demonstrate how resting state functional magnetic resonance imaging (fMRI) signals may be used to objectively parcellate functionally heterogeneous subregions of the human amygdala into structures characterized by similar patterns of functional connectivity. We hypothesize that simi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22249

    authors: Mishra A,Rogers BP,Chen LM,Gore JC

    更新日期:2014-04-01 00:00:00

  • Metabolic correlates of cognitive function in children with unilateral Sturge-Weber syndrome: Evidence for regional functional reorganization and crowding.

    abstract::To evaluate metabolic changes in the ipsi- and contralateral hemisphere in children showing a cognitive profile consistent with early reorganization of cognitive function, we evaluated the regional glucose uptake, interhemispheric metabolic connectivity, and cognitive function in children with unilateral SWS. Interict...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23937

    authors: Kim JA,Jeong JW,Behen ME,Pilli VK,Luat A,Chugani HT,Juhász C

    更新日期:2018-04-01 00:00:00

  • Age-related decline in task switching is linked to both global and tract-specific changes in white matter microstructure.

    abstract::Task-switching performance relies on a broadly distributed frontoparietal network and declines in older adults. In this study, they investigated whether this age-related decline in task switching performance was mediated by variability in global or regional white matter microstructural health. Seventy cognitively inta...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23473

    authors: Jolly TA,Cooper PS,Rennie JL,Levi CR,Lenroot R,Parsons MW,Michie PT,Karayanidis F

    更新日期:2017-03-01 00:00:00

  • Voxelwise and skeleton-based region of interest analysis of fetal alcohol syndrome and fetal alcohol spectrum disorders in young adults.

    abstract::Though fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorders are among the most common developmental disorders, their understanding is incomplete. Diffusion tensor imaging (DTI), which is sensitive to microstructural organization in white matter, may provide a relevant measure in this population demonstrat...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20747

    authors: Li L,Coles CD,Lynch ME,Hu X

    更新日期:2009-10-01 00:00:00

  • Linear and nonlinear interrelations show fundamentally distinct network structure in preictal intracranial EEG of epilepsy patients.

    abstract::Resection of the seizure generating tissue can be highly beneficial in patients with drug-resistant epilepsy. However, only about half of all patients undergoing surgery get permanently and completely seizure free. Investigating the dependences between intracranial EEG signals adds a multivariate perspective largely u...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24816

    authors: Müller M,Caporro M,Gast H,Pollo C,Wiest R,Schindler K,Rummel C

    更新日期:2020-02-01 00:00:00

  • Inhibitory saccadic dysfunction is associated with cerebellar injury in multiple sclerosis.

    abstract::Cognitive dysfunction is common in patients with multiple sclerosis (MS). Saccadic eye movement paradigms such as antisaccades (AS) can sensitively interrogate cognitive function, in particular, the executive and attentional processes of response selection and inhibition. Although we have previously demonstrated signi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22329

    authors: Kolbe SC,Kilpatrick TJ,Mitchell PJ,White O,Egan GF,Fielding J

    更新日期:2014-05-01 00:00:00

  • Strategic white matter injury associated with long-term information processing speed deficits in mild traumatic brain injury.

    abstract::Deficits in information processing speed (IPS) are among the earliest and most prominent cognitive manifestations in mild traumatic brain injury (mTBI). We investigated the impact of white matter fiber location on IPS outcome in an individual basis assessment. A total of 112 acute mild TBI with all CT negative underwe...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25135

    authors: Bai L,Bai G,Wang S,Yang X,Gan S,Jia X,Yin B,Yan Z

    更新日期:2020-07-13 00:00:00

  • An event-related FMRI study of exogenous orienting across vision and audition.

    abstract::The orienting of attention to the spatial location of sensory stimuli in one modality based on sensory stimuli presented in another modality (i.e., cross-modal orienting) is a common mechanism for controlling attentional shifts. The neuronal mechanisms of top-down cross-modal orienting have been studied extensively. H...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22227

    authors: Yang Z,Mayer AR

    更新日期:2014-03-01 00:00:00

  • Neural decoding of visual stimuli varies with fluctuations in global network efficiency.

    abstract::Functional magnetic resonance imaging (fMRI) studies have shown that neural activity fluctuates spontaneously between different states of global synchronization over a timescale of several seconds. Such fluctuations generate transient states of high and low correlation across distributed cortical areas. It has been hy...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23574

    authors: Cocchi L,Yang Z,Zalesky A,Stelzer J,Hearne LJ,Gollo LL,Mattingley JB

    更新日期:2017-06-01 00:00:00

  • Functional interactions between oculomotor regions during prosaccades and antisaccades.

    abstract::Human behavior reflects a continual negotiation of automatic and directed actions. The oculomotor network is a well-characterized neural system in which to study this balance of behavioral control. For instance, saccades made toward and away from a flashed visual stimulus (prosaccades and antisaccades, respectively) a...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20146

    authors: Miller LM,Sun FT,Curtis CE,D'Esposito M

    更新日期:2005-10-01 00:00:00

  • Dissociation of mnemonic and perceptual processes during spatial and nonspatial working memory using fMRI.

    abstract::Neuroimaging studies in humans have consistently found robust activation of frontal, parietal, and temporal regions during working memory tasks. Whether these activations represent functional networks segregated by perceptual domain is still at issue. Two functional magnetic resonance imaging experiments were conducte...

    journal_title:Human brain mapping

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Belger A,Puce A,Krystal JH,Gore JC,Goldman-Rakic P,McCarthy G

    更新日期:1998-01-01 00:00:00

  • Predicting and memorizing observed action: differential premotor cortex involvement.

    abstract::Many studies have shown the involvement of the premotor cortex in action observation, recognizing this region as the neural marker of action simulation (i.e., internal modeling on the basis of the observer's own motor repertoire). So far, however, we have remained unaware of how action simulation differs from more gen...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20949

    authors: Stadler W,Schubotz RI,von Cramon DY,Springer A,Graf M,Prinz W

    更新日期:2011-05-01 00:00:00

  • Abnormal neural response to phonological working memory demands in persistent developmental stuttering.

    abstract::Persistent developmental stuttering is a neurological disorder that commonly manifests as a motor problem. Cognitive theories, however, hold that poorly developed cognitive skills are the origins of stuttering. Working memory (WM), a multicomponent cognitive system that mediates information maintenance and manipulatio...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24366

    authors: Yang Y,Jia F,Fox PT,Siok WT,Tan LH

    更新日期:2019-01-01 00:00:00

  • Modality specific functional interaction in sensorimotor synchronization.

    abstract::Movement execution strongly relies on precise sensorimotor synchronization. In a finger-tapping task that requires subjects to synchronize their finger taps to regular pacing signal synchronization accuracy varies with respect to pacing signal's modality. This study aimed at elucidating functional brain dynamics assoc...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20762

    authors: Pollok B,Krause V,Butz M,Schnitzler A

    更新日期:2009-06-01 00:00:00