Abstract:
Background:Fear of necrotizing enterocolitis (NEC) has perpetuated delayed initiation and slow advancement of enteral feeding in very low birth weight (VLBW) infants with inherent risks of parenteral alimentation. The objective of this study was to assess effect of early total enteral feeding (ETEF) on day of achievement of full enteral feeds, feed intolerance, NEC and sepsis. Methods:In total, 208 stable VLBW neonates (28-34 weeks) admitted during 6 month periods of three consecutive years were enrolled. First phase (n = 73) constituted the 'before' phase with standard practice of initial intravenous fluid therapy and slow enteral feeding. The second prospective phase (n = 51) consisted of implementation of ETEF with infants receiving full enteral feeds as per day's fluid requirement since Day 1 of life. The third phase (n = 84) was chosen to assess the sustainability of change in practice. Results:Day of achievement of full feeds was significantly earlier in Phases 2 and 3 compared with Phase 1 (8.97 and 5.47 vs. 14.44 days, respectively, p = 0.0001). Incidence of feed intolerance was comparable between Phases 1 and 2 (22 vs. 14%, p = 0.28), with marked reduction in incidence of NEC (14 vs. 4%, p = 0.028). There was a significant decrease in sepsis, duration of parenteral fluid and antibiotic therapy as well as hospital stay with comparable mortality. Conclusion:In stable preterm VLBW infants, ETEF is safe and has the benefit of optimizing nutrition with decrease in sepsis, NEC and hospital stay.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Nangia S,Bishnoi A,Goel A,Mandal P,Tiwari S,Saili Adoi
10.1093/tropej/fmx023subject
Has Abstractpub_date
2018-02-01 00:00:00pages
24-30issue
1eissn
0142-6338issn
1465-3664pii
3739807journal_volume
64pub_type
杂志文章abstract::Abdominal pain-predominant functional gastrointestinal diseases (AP-FGD) are common in children and commonly attributed to exposure to child abuse. However, this relationship has not been studied in teenagers, and the main objective of the current study was to assess it. Teenagers were recruited from four randomly sel...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
abstract::This is a descriptive study of short-course chemotherapy in children with nodal tuberculosis at Port Moresby General Hospital (PMGH). Between 1 August 1989 and 31 December 1997 5248 children were started on TB treatment. In the retrospective study 427 children were treated for lymph node TB up to 31 December 1996. Of ...
journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
abstract::Till date, there is paucity of published literature on clinical manifestations of Coronavirus disease 2019 (COVID-19) in children from low-middle-income countries (LMIC). Most of the reports are from Europe, USA or China. Our study aimed to capture data on varied and unusual clinical presentation and management of MIS...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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abstract:BACKGROUND:The mother-to-child transmission of HIV, which accounts for 90% of infections in children, has been reduced markedly through the use of antiretroviral drugs by pregnant women and their newborns. Changes to the World Health Organization guidelines support further extension of the prevention of mother-to-child...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/42.6.342
更新日期:1996-12-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
abstract::Ninety-one consecutive cases of coma were identified among gravidas at Maputo Central Hospital. The commonest causes were eclampsia (70 cases), cerebral malaria (six cases), and meningitis (five cases). Fetal mortality in eclampsia was 23 per cent and maternal mortality 10 per cent. There was a markedly higher inciden...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/38.3.100
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abstract::Exclusive breastfeeding (EBF) is being promoted by WHO/UNICEF as the recommended mode of feeding for all infants from birth to around 6 months of age. It is also recommended for the initial few months, for infants born to HIV-positive mothers in the developing world where conditions may not be ideal for replacement fe...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2004-12-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.1.35
更新日期:1989-02-01 00:00:00
abstract::The seroepidemiology of infection due to rubella virus in Saudi Arabia was investigated in various age groups including unvaccinated children (newborn to 15 years of age) using a newer rubella antibody test system, the ELISA with maximum sensitivity and reliability. The assessment of the immune status indicated the lo...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.4.169
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn031
更新日期:2008-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmu034
更新日期:2014-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.6.291
更新日期:1989-12-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi078
更新日期:2006-04-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/47.5.295
更新日期:2001-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:1992-02-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 信件
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更新日期:2014-06-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.6.277
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:1998-02-01 00:00:00
abstract::Iodine deficiency disorders IDD are major public health problems in India, including West Bengal. Existing programme to control IDD needs to be continuously monitored through recommended methods and indicators. The objective of this study was to assess the prevalence of goitre, status of urinary iodine excretion UIE l...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:1999-02-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-12-01 00:00:00
abstract:AIM:There is insufficient knowledge on the * duodenal histology and Helicobacter pylori infection in malnourished Bangladeshi children. Therefore, we attempted to explore the prevalence of H. pylori infection and duodenal histopathology in 2-year-old chronic malnourished Bangladeshi slum-dwelling children and investiga...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2020-10-25 00:00:00