Regulatory role of G9a and LSD1 in the Transcription of Olfactory Receptors during Leukaemia Cell Differentiation.

abstract：:Agrostemma githago L. (corn cockle) is an herbaceous plant mainly growing in Europe. The seeds of the corn cockle are toxic and poisonings were widespread in the past by consuming contaminated flour. The toxic principle of Agrostemma seeds was attributed to triterpenoid secondary metabolites. Indeed, this is in part t...

journal_title：Scientific reports

authors： Weise C,Schrot A,Wuerger LTD,Adolf J,Gilabert-Oriol R,Sama S,Melzig MF,Weng A

更新日期：2020-09-21 00:00:00

abstract：:Controlled ovarian stimulation by exogenous gonadotrophins is a key procedure during the in vitro fertilization cycle to obtain a sufficient number of oocytes in humans. Previous studies demonstrated that repeated superovulation had deleterious effects on the ovaries. However, whether repeated superovulation adversely...

journal_title：Scientific reports

authors： Xie JK,Wang Q,Zhang TT,Yin S,Zhang CL,Ge ZJ

更新日期：2016-10-04 00:00:00

abstract：:The analysis of the choroid in the eye is crucial for our understanding of a range of ocular diseases and physiological processes. Optical coherence tomography (OCT) imaging provides the ability to capture highly detailed cross-sectional images of the choroid yet only a very limited number of commercial OCT instrument...

journal_title：Scientific reports

authors： Kugelman J,Alonso-Caneiro D,Read SA,Hamwood J,Vincent SJ,Chen FK,Collins MJ

更新日期：2019-09-16 00:00:00

abstract：:Fear is an adaptive emotion that elicits defensive behavioural responses against aversive threats in animals. In mammals, serotonin receptors (5-HTRs) have been shown to modulate fear-related neural circuits in the basolateral amygdala complex (BLA). To understand the phylogenetic continuity of the neural basis for fe...

journal_title：Scientific reports

authors： Fujita T,Aoki N,Mori C,Fujita E,Matsushima T,Homma KJ,Yamaguchi S

更新日期：2020-12-03 00:00:00

abstract：:The availability of genotyping assays has allowed the detailed evaluation of cattle genetic diversity worldwide. However, these comprehensive studies did not include some local European populations, including autochthonous Italian cattle. In this study, we assembled a large-scale, genome-wide dataset of single nucleot...

journal_title：Scientific reports

authors： Mastrangelo S,Tolone M,Ben Jemaa S,Sottile G,Di Gerlando R,Cortés O,Senczuk G,Portolano B,Pilla F,Ciani E

更新日期：2020-09-03 00:00:00

abstract：:In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...

journal_title：Scientific reports

authors： Giddey AD,de Kock E,Nakedi KC,Garnett S,Nel AJ,Soares NC,Blackburn JM

更新日期：2017-03-06 00:00:00

abstract：:Integrated photonics promises solutions to questions of stability, complexity, and size in quantum optics. Advances in tunable and non-planar integrated platforms, such as laser-inscribed photonics, continue to bring the realisation of quantum advantages in computation and metrology ever closer, perhaps most easily se...

journal_title：Scientific reports

authors： Chaboyer Z,Meany T,Helt LG,Withford MJ,Steel MJ

更新日期：2015-04-27 00:00:00

abstract：:Because of its novel physical properties, two-dimensional materials have attracted great attention. From first-principle calculations and vibration frequencies analysis, we predict a new family of two-dimensional materials based on the idea of octet stability: honeycomb lattices of pnictogens (N, P, As, Sb, Bi). The b...

journal_title：Scientific reports

authors： Lee J,Tian WC,Wang WL,Yao DX

更新日期：2015-06-30 00:00:00

abstract：:Milk microbiota has a great influence on the safety and quality of dairy products. However, few studies have investigated the variations of bacterial composition in raw milk. In this study, raw milk samples were collected in 12 successive months, and their bacterial compositions were determined by 16 S rRNA gene seque...

journal_title：Scientific reports

authors： Li N,Wang Y,You C,Ren J,Chen W,Zheng H,Liu Z

更新日期：2018-02-05 00:00:00

abstract：:Ongoing studies of a multiple track-bearing horizons from massive excavations in the Jinju Formation (Lower Cretaceous) of South Korea have yielded a remarkable diversity of avian, non-avian dinosaur, pterosaur, crocodilian and mammal tracks, many very small and well preserved. Here we report diminutive, didactyl trac...

journal_title：Scientific reports

authors： Kim KS,Lim JD,Lockley MG,Xing L,Kim DH,Piñuela L,Romilio A,Yoo JS,Kim JH,Ahn J

更新日期：2018-11-15 00:00:00

abstract：:A number of studies have reported that the digit ratio 2D:4D (length of the second finger divided by length of the fourth finger) is smaller (longer fourth digit) in autism spectrum disorder (ASD) than in typically developed (TD) controls. Because form and function are closely related in biological systems, we hypothe...

journal_title：Scientific reports

authors： Togo S,Itahashi T,Hashimoto R,Cai C,Kanai C,Kato N,Imamizu H

更新日期：2019-02-11 00:00:00

abstract：:This study aims to identify a panel of blood-cell neuroplasticity-related genes expressed following environmental enrichment stimulation (EE). The Drug detection (DD) training course was an excellent model for the study of EE in the working dog. This research is divided into two experimental trials. In the First Trial...

journal_title：Scientific reports

authors： Guelfi G,Casano AB,Menchetti L,Bellicci M,Suvieri C,Moscati L,Carotenuto P,Santoro MM,Diverio S

更新日期：2019-05-06 00:00:00

abstract：:The binding of metal ions at the interface of protein complexes presents a unique and poorly understood mechanism of molecular assembly. A remarkable example is the Rad50 zinc hook domain, which is highly conserved and facilitates the Zn2+-mediated homodimerization of Rad50 proteins. Here, we present a detailed analys...

journal_title：Scientific reports

authors： Kochańczyk T,Nowakowski M,Wojewska D,Kocyła A,Ejchart A,Koźmiński W,Krężel A

更新日期：2016-11-03 00:00:00

abstract：:We demonstrate a novel route to achieving highly efficient and strongly confined spoof surface plasmon polaritons (SPPs) waveguides at subwavelength scale enabled by planar staggered plasmonic waveguides (PSPWs). The structure of these new waveguides consists of an ultrathin metallic strip with periodic subwavelength ...

journal_title：Scientific reports

authors： Ye L,Xiao Y,Liu Y,Zhang L,Cai G,Liu QH

更新日期：2016-12-05 00:00:00

abstract：:New insect pest control agents are needed to meet the demands to feed an expanding global population, to address the desire for more environmentally-friendly insecticide tools, and to fill the loss of control options in some crop-pest complexes due to development of insecticide resistance. The spinosyns are a highly e...

journal_title：Scientific reports

authors： Crouse GD,Demeter DA,Samaritoni G,McLeod CL,Sparks TC

更新日期：2018-03-20 00:00:00

abstract：:Numerous studies have investigated the association between eosinophilia and clinical outcome of patients with chronic obstructive pulmonary disease (COPD) but the evidence is conflicting. We conducted a pooled analysis of outcome measures comparing eosinophilic and non-eosinophilic COPD patients. We searched articles ...

journal_title：Scientific reports

authors： Ho J,He W,Chan MTV,Tse G,Liu T,Wong SH,Leung CCH,Wong WT,Tsang S,Zhang L,Chan RYP,Gin T,Leung J,Lau BWM,Wu WKK,Ngai SPC

更新日期：2017-10-18 00:00:00

abstract：:The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate...

journal_title：Scientific reports

authors： Wang CY,Xia JG,Yang ZQ,Zhou WZ,Chen WH,Qi CJ,Gu JP,Wang Q

更新日期：2020-03-10 00:00:00

abstract：:Uterosacral ligaments (USLs) provide structural support to the female pelvic floor, and a loss of USL structural integrity or biomechanical function may induce pelvic organ prolapse (POP). Alterations in extracellular matrix composition and organization dictate USL mechanical function. Changes in USL microstructure an...

journal_title：Scientific reports

authors： Danso EK,Schuster JD,Johnson I,Harville EW,Buckner LR,Desrosiers L,Knoepp LR,Miller KS

更新日期：2020-04-30 00:00:00

abstract：:Pre-stimulus alpha (8-12 Hz) and beta (16-20 Hz) oscillations have been frequently linked to the prediction of upcoming sensory input. Do these frequency bands serve as a neural marker of linguistic prediction as well? We hypothesized that if pre-stimulus alpha and beta oscillations index language predictions, their p...

journal_title：Scientific reports

authors： Terporten R,Schoffelen JM,Dai B,Hagoort P,Kösem A

更新日期：2019-12-27 00:00:00

abstract：:The subjective experience of thermal pain follows the detection and encoding of noxious stimuli by primary afferent neurons called nociceptors. However, nociceptor morphology has been hard to access and the mechanisms of signal transduction remain unresolved. In order to understand how heat transducers in nociceptors ...

journal_title：Scientific reports

authors： Dezhdar T,Moshourab RA,Fründ I,Lewin GR,Schmuker M

更新日期：2015-12-07 00:00:00

abstract：:Hookworms are one of the most prevalent and important parasites, infecting ~500 million people worldwide. Hookworm disease is among the leading causes of iron-deficiency anemia in the developing world and is associated with significant growth stunting and malnutrition. In humans, hookworms appear to impair memory and ...

journal_title：Scientific reports

authors： Pan SC,Ward DV,Yin Y,Hu Y,Elfawal MA,Clark RE,Aroian RV

更新日期：2019-05-27 00:00:00

abstract：:Ferroelectric-relaxor behavior of Ba(Zr0.3Ti0.7)O3 nanofibers (BZT NF) with a large aspect ratio were prepared via electrospinning and surface modified by PVP as dielectric fillers. The nanocomposite flexible films based on surface modified BZT NF and polyvinylidene fluoride (PVDF) were fabricated via a solution casti...

journal_title：Scientific reports

authors： Liu S,Xue S,Xiu S,Shen B,Zhai J

更新日期：2016-05-17 00:00:00

abstract：:The one-step nucleic acid amplification (OSNA) assay is a molecular procedure that can identify deposits of breast cancer (BC) cells in the sentinel lymph node (SLN). We examined the consistency of the OSNA assay with a classic hematoxylin-eosin (H&E)-based immunohistochemistry (IHC) study and evaluated how OSNA-based...

journal_title：Scientific reports

authors： Ruano MA,Lopez-Bonet E,Buxó M,Tuca-Rodríguez F,Vila-Camps E,Alvarez E,Martin-Castillo B,Menendez JA

更新日期：2014-07-18 00:00:00

abstract：:Sampling the concentration of insulin in human skin using microdialysis is challenging because of low intracutaneous concentrations and low recovery, presumably due to adsorption of insulin to the microdialysis system. In this study, we aimed to (1) measure how the concentration of insulin varies in three different ti...

journal_title：Scientific reports

authors： Högstedt A,Ghafouri B,Tesselaar E,Farnebo S

更新日期：2020-12-15 00:00:00

abstract：:To identify a vegetation configuration pattern with a high-efficiency purification ability for total nitrogen (TN), available nitrogen (AN), total phosphorous (TP), available phosphorous (AP), and chemical oxygen demand (COD) based on comprehensive assessment results, a water discharge experiment was performed in the ...

journal_title：Scientific reports

authors： Hou G,Bi H,Yu X,Jia G,Wang D,Zhang Z,Liu Z

更新日期：2019-02-20 00:00:00

abstract：:Elucidation of temperature tolerance mechanisms in yeast is essential for enhancing cellular robustness of strains, providing more economically and sustainable processes. We investigated the differential responses of three distinct Saccharomyces cerevisiae strains, an industrial wine strain, ADY5, a laboratory strain,...

journal_title：Scientific reports

authors： Pinheiro T,Lip KYF,García-Ríos E,Querol A,Teixeira J,van Gulik W,Guillamón JM,Domingues L

更新日期：2020-12-18 00:00:00

abstract：:Despite the development of crystal engineering, it remains a great challenge to predict the crystal structure even for the simplest molecules, and a clear link between molecular and crystal symmetry is missing in general. Here we demonstrate that the two-dimensional (2D) crystallization of heterocirculenes on a Au(111...

journal_title：Scientific reports

authors： Xiao WD,Zhang YY,Tao L,Aït-Mansour K,Chernichenko KY,Nenajdenko VG,Ruffieux P,Du SX,Gao HJ,Fasel R

更新日期：2014-06-24 00:00:00

abstract：:Extracellular vesicles (EVs) have important roles in physiology, pathology, and more recently have been identified as efficient carriers of therapeutic cargoes. For efficient study of EVs, a single-step, rapid and scalable isolation strategy is necessary. Chromatography techniques are widely used for isolation of biol...

journal_title：Scientific reports

authors： Heath N,Grant L,De Oliveira TM,Rowlinson R,Osteikoetxea X,Dekker N,Overman R

更新日期：2018-04-10 00:00:00

abstract：:The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show th...

journal_title：Scientific reports

authors： Vo U,Vajpai N,Embrey KJ,Golovanov AP

更新日期：2016-07-14 00:00:00

abstract：:Encapsulation is essential to protect the air-sensitive components of organic light-emitting diodes (OLEDs) such as active layers and cathode electrodes. In this study, hybrid zirconium inorganic/organic nanolaminates were fabricated using remote plasma enhanced atomic layer deposition (PEALD) and molecular layer depo...

journal_title：Scientific reports

authors： Chen Z,Wang H,Wang X,Chen P,Liu Y,Zhao H,Zhao Y,Duan Y

更新日期：2017-01-06 00:00:00