Recombinant Adeno-Associated Virus-Mediated Expression of Methamphetamine Antibody Attenuates Methamphetamine-Induced Hyperactivity in Mice.

abstract：:Although Heme Oxygenase-1 (HO-1) induction in various forms of kidney injury is protective, its role in age-related renal pathology is unknown. In the ageing kidney there is nephron loss and lesions of focal glomerulosclerosis, interstitial fibrosis, tubular atrophy and arteriolosclerosis. Underlying mechanisms includ...

journal_title：Scientific reports

authors： Poulaki E,Detsika MG,Fourtziala E,Lianos EA,Gakiopoulou H

更新日期：2020-03-31 00:00:00

abstract：:Pseudoalteromonas haloplanktis TAC125 is among the most commonly studied bacteria adapted to cold environments. Aside from its ecological relevance, P. haloplanktis has a potential use for biotechnological applications. Due to its importance, we decided to take advantage of next generation sequencing (Illumina) and th...

journal_title：Scientific reports

authors： Qi W,Colarusso A,Olombrada M,Parrilli E,Patrignani A,Tutino ML,Toll-Riera M

更新日期：2019-11-11 00:00:00

abstract：:To elude the strength-electrical conductivity trade-off dilemma, a nanostructuring strategy was achieved in microalloyed Al-0.1wt.% Zr conductor by optimizing the processing route, leading to enhanced strength and simultaneously improved electrical conductivity. The nanostructural design involved ultrafine grains with...

journal_title：Scientific reports

authors： Jiang SY,Wang RH

更新日期：2018-04-18 00:00:00

abstract：:The nuclear receptor, farnesoid X receptor (FXR), has been recently considered as a tumor suppressor in HCC. IL-6/Janus kinase 2 (Jak-2)/signal transducer and activator of transcription 3 (STAT3) pathway has been implicated as a key player in many cancer types. This study aimed at investigating the potential effect of...

journal_title：Scientific reports

authors： Attia YM,Tawfiq RA,Ali AA,Elmazar MM

更新日期：2017-10-02 00:00:00

abstract：:Photoactivated localization microscopy (PALM) is a super-resolution imaging technique based on the detection and subsequent localization of single fluorescent molecules. PALM is therefore a powerful tool in resolving structures and putative interactions of biomolecules at the ultimate analytical detection limit. Howev...

journal_title：Scientific reports

authors： Vangindertael J,Beets I,Rocha S,Dedecker P,Schoofs L,Vanhoorelbeke K,Hofkens J,Mizuno H

更新日期：2015-09-01 00:00:00

abstract：:Ge-monopnictides (GeAs) plays critical role in high-tech industry, especially in the field of advanced optical devices and infrared. As a secondary material, coal fly ash could be further recycled to retrieve germanium and prepare GeAs material with high added values. Hence, the aim of this paper is to propose a one-p...

journal_title：Scientific reports

authors： Zhang L,Xu Z

更新日期：2017-06-16 00:00:00

abstract：:The conventional multifocal optical elements cannot precisely control the focal number, spot size, as well as the energy distribution in between. Here, the binary amplitude-type super-oscillatory lens (SOL) is utilized, and a robust and universal optimization method based on the vectorial angular spectrum (VAS) theory...

journal_title：Scientific reports

authors： Li M,Li W,Li H,Zhu Y,Yu Y

更新日期：2017-05-02 00:00:00

abstract：:In this article, the interaction between bovine serum albumin (BSA) and the cationic 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) at the air-buffer interface was investigated at different subphase's pH values (pH = 3, 5 and 10). Surface pressure measurements (π - A) and penetration kinetics process (π - t) were ca...

journal_title：Scientific reports

authors： Xu G,Hao C,Zhang L,Sun R

更新日期：2018-01-10 00:00:00

abstract：:The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susceptible to infection over the...

journal_title：Scientific reports

authors： Birchenough GM,Dalgakiran F,Witcomb LA,Johansson ME,McCarthy AJ,Hansson GC,Taylor PW

更新日期：2017-03-06 00:00:00

abstract：:This study for the first time examined the prophylactic role of Tungrymbai, a well-known fermented soybean food of North-East India, against hepatic steatosis. Treatment with hexane-isopropanolic (2:1, HIET) but not hydro-alcoholic (70% ethanol, HAET) extract dose-dependently (0.1, 0.2, or 0.3 µg/mL) reduced the intra...

journal_title：Scientific reports

authors： Dihingia A,Bordoloi J,Dutta P,Kalita J,Manna P

更新日期：2018-07-03 00:00:00

abstract：:Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins whose role as drug targets against pathogens, as well as in valuable chemical production and bioremediation, has been explored. In this study we performed comprehensive comparative analysis of P450s in 13 newly explored oomycete pathogens. Three hundred...

journal_title：Scientific reports

authors： Sello MM,Jafta N,Nelson DR,Chen W,Yu JH,Parvez M,Kgosiemang IKR,Monyaki R,Raselemane SC,Qhanya LB,Mthakathi NT,Sitheni Mashele S,Syed K

更新日期：2015-07-01 00:00:00

abstract：:Marine plant communities such as kelp forests produce significant amounts of detritus, most of which is exported to areas where it can constitute an important trophic subsidy or potentially be sequestered in marine sediments. Knowing the vertical transport speed of detrital particles is critical to understanding the p...

journal_title：Scientific reports

authors： Wernberg T,Filbee-Dexter K

更新日期：2018-11-21 00:00:00

abstract：:AMP-activated protein kinase (AMPK) is a key sensor and regulator of glucose metabolism. Here, we demonstrated that shizukaol F, a natural compound isolated from Chloranthus japonicus, can activate AMPK and modulate glucose metabolism both in vitro and in vivo. Shizukaol F increased glucose uptake in differentiated C2...

journal_title：Scientific reports

authors： Hu R,Yan H,Fei X,Liu H,Wu J

更新日期：2017-04-10 00:00:00

abstract：:Vancomycin-resistant Staphylococcus aureus (VRSA), Vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA) are subject to vancomycin treatment failure. The aim of the present study was to determine their precise prevalence and investigate prevalence variability depending on different years and location...

journal_title：Scientific reports

authors： Shariati A,Dadashi M,Moghadam MT,van Belkum A,Yaslianifard S,Darban-Sarokhalil D

更新日期：2020-07-29 00:00:00

abstract：:Charge noise is critical in the performance of gate-controlled quantum dots (QDs). Such information is not yet available for QDs made out of the new material graphene, where both substrate and edge states are known to have important effects. Here we show the 1/f noise for a microscopic graphene QD is substantially lar...

journal_title：Scientific reports

authors： Song XX,Li HO,You J,Han TY,Cao G,Tu T,Xiao M,Guo GC,Jiang HW,Guo GP

更新日期：2015-01-30 00:00:00

abstract：:Individuals who have prior history of childhood traumatic experiences are at a high risk for a variety of psychological and behavioral problems throughout their lifetime. This study aimed to investigate whether such individuals exhibit altered cortical functional networks during a behavioral inhibition task. One hundr...

journal_title：Scientific reports

authors： Kim S,Kim JS,Shim M,Im CH,Lee SH

更新日期：2018-07-04 00:00:00

abstract：:Urothelial carcinoma (UC) is a common disease causing significant morbidity and mortality as well as considerable costs for health systems. Extensive aberrant methylation of DNA is broadly documented in early UC, contributing to genetic instability, altered gene expression and tumor progression. However the triggers i...

journal_title：Scientific reports

authors： Erichsen L,Seifert HH,Schulz WA,Hoffmann MJ,Niegisch G,Araúzo-Bravo MJ,Bendhack ML,Poyet C,Hermanns T,Beermann A,Hassan M,Theis L,Mahmood W,Santourlidis S

更新日期：2020-03-02 00:00:00

abstract：:Influence of polyethylene glycol (PEG) mediated osmotic stress on reactive oxygen species (ROS) scavenging machinery of Chinese potato (Solenostemon rotundifolius (Poir.) J. K. Morton) was investigated. Five genotypes of Chinese potato were raised in Murashige and Skoog (MS) basal medium containing 6-benzylaminopurine...

journal_title：Scientific reports

authors： Sahoo MR,Devi TR,Dasgupta M,Nongdam P,Prakash N

更新日期：2020-03-25 00:00:00

abstract：:We analyse theoretically the spatiotemporal dynamics of two incoherent counterpropagating Airy beams interacting in a photorefractive crystal under focusing conditions. For a large enough nonlinearity strength the interaction between the two Airy beams leads to light-induced waveguiding. The stability of the waveguide...

journal_title：Scientific reports

authors： Wiersma N,Marsal N,Sciamanna M,Wolfersberger D

更新日期：2015-08-28 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss that ultimately leads to fatal paralysis. Reducing levels or function of the tyrosine kinase, ephrin type-A receptor 4 (EphA4), has been suggested as a potential approach for slowing disease progression in ALS. Becaus...

journal_title：Scientific reports

authors： Dominguez SL,Earr T,Dourado M,Ngu H,Meilandt WJ,Hanson JE

更新日期：2020-09-24 00:00:00

abstract：:Diffusion tensor imaging (DTI) studies have detected white matter microstructural changes in essential tremor (ET). However, it is still unclear whether these changes are related to cognitive deficits, which have been described in ET patients. DTI-derived fractional anisotropy, mean diffusivity (MD), axial diffusivity...

journal_title：Scientific reports

authors： Benito-León J,Mato-Abad V,Louis ED,Hernández-Tamames JA,Álvarez-Linera J,Bermejo-Pareja F,Domingo-Santos Á,Collado L,Romero JP

更新日期：2017-06-07 00:00:00

abstract：:We demonstrate a label-free imaging approach to study cardiac remodeling of fibrotic and hypertrophic hearts, bridging scales from the whole organ down to the molecular level. To this end, we have used mice subjected to transverse aortic constriction and imaged adjacent cardiac tissue sections by microfocus X-ray diff...

journal_title：Scientific reports

authors： Nicolas JD,Khan A,Markus A,Mohamed BA,Toischer K,Alves F,Salditt T

更新日期：2020-11-09 00:00:00

abstract：:Recently, a large number of long noncoding RNAs (lncRNAs) have emerged as important regulators of many biological processes in animals and plants. However, how lncRNAs function during plant DNA virus infection is largely unknown. We performed strand-specific paired-end RNA sequencing of tomato samples infected with To...

journal_title：Scientific reports

authors： Wang J,Yu W,Yang Y,Li X,Chen T,Liu T,Ma N,Yang X,Liu R,Zhang B

更新日期：2015-12-18 00:00:00

abstract：:Area under a receiver-operating-characteristic (AUROC) curve is widely used in medicine to summarize the ability of a continuous predictive marker to predict a binary outcome. This study illustrated how a U-shaped or inverted U-shaped continuous predictor would affect the shape and magnitude of its AUROC curve in pred...

journal_title：Scientific reports

authors： Ho KM

更新日期：2017-08-31 00:00:00

abstract：:We performed a metabolomics study using liquid chromatography-mass spectrometry (LC-MS) combined with multivariate data analysis (MVDA) to discriminate global urine profiles in urine samples from esophageal squamous cell carcinoma (ESCC) patients and healthy controls (NC). Our work evaluated the feasibility of employi...

journal_title：Scientific reports

authors： Xu J,Chen Y,Zhang R,He J,Song Y,Wang J,Wang H,Wang L,Zhan Q,Abliz Z

更新日期：2016-10-11 00:00:00

abstract：:α-Ketoglutarate (αKG) is a metabolite of the tricarboxylic acid cycle, important for biomass synthesis and a precursor for biotechnological products like 1,4-butanediol. In the eukaryote Saccharomyces cerevisiae αKG is present in different compartments. Compartmentation and (intra-)cellular transport could interfere w...

journal_title：Scientific reports

authors： Zhang J,van den Herik BM,Wahl SA

更新日期：2020-07-30 00:00:00

abstract：:Hybrid cells of Nicotiana suaveolens x N. tabacum grow normally at 36 °C, but immediately express lethality due to probable autoimmune response when transferred from 36 to 28 °C. Our recent study showed that the temperature-sensitive lethality of these hybrid cells occurs through autolytic programmed cell death (PCD)....

journal_title：Scientific reports

authors： Ueno N,Kashiwagi M,Kanekatsu M,Marubashi W,Yamada T

更新日期：2019-07-15 00:00:00

abstract：:Curcumin is an important bioactive component of turmeric and also one of the important natural products, which has been investigated extensively. The precise mode of action of curcumin and its impact on system level protein networks are still not well studied. To identify the curcumin governed regulatory action on pro...

journal_title：Scientific reports

authors： Dhasmana A,Uniyal S,Anukriti,Kashyap VK,Somvanshi P,Gupta M,Bhardwaj U,Jaggi M,Yallapu MM,Haque S,Chauhan SC

更新日期：2020-07-21 00:00:00

abstract：:The mitogen-activated protein kinase (MAPK) cascades, which play crucial roles in plant development processes, are universal modules of signal transduction in eukaryotes and consist of a core module of three sequentially phosphorylated kinases: MAPK, MAPK kinase (MAPKK), and MAPKK kinase (MAPKKK). This is the first re...

journal_title：Scientific reports

authors： Jing T,Wang L,Liu H,Wuyun TN,Du H

更新日期：2017-12-18 00:00:00

abstract：:Continuous solidification experiments were carried out with Cu-Bi-Sn alloys under the effects of Electric Current Pulses (ECPs). A model describing the microstructure evolution was developed. The formation of the microstructure in the continuously solidified alloys was calculated. The calculations demonstrated that EC...

journal_title：Scientific reports

authors： Hongxiang J,Jie H,Jiuzhou Z

更新日期：2015-07-31 00:00:00