Erratum to Parasrampuria et al. "Pharmacokinetics, safety, and tolerability of edoxaban in end-stage renal disease subjects undergoing haemodialysis" (Thromb Haemost 2015; 113: 719-727).

abstract：:Sequential treatment of arterial occlusions of the leg with porcine plasmin and low dose streptokinase results in a strong systemic proteolysis as already seen in deep leg vein thrombosis. In 31 of 45 patients the blood flow through major arterial segments could be restored. Thrombolytic success is possible within the...

journal_title：Thrombosis and haemostasis

authors： Marbet GA,Eichlisberger R,Duckert F,da Silva MA,Biland L,Widmer LK,Ritz R,Schmitt HE

更新日期：1982-10-29 00:00:00

abstract：:Vascular endothelial cells perform many differentiated functions in processes such as angiogenesis, hemostasis, and inflammation. The number of recognized differentiated functions has increased rapidly in recent years, but there may be many more still unrecognized. The purpose of this study is to estimate the fraction...

journal_title：Thrombosis and haemostasis

authors： Rieber AJ,Marr HS,Comer MB,Edgell CJ

更新日期：1993-05-03 00:00:00

abstract：:Hemorrhagic diathesis was observed in patients with renal insufficiency after carbenicillin at serum levels greater than 300 mug/ml. Normal coagulation factors (F. I, II, V, VII, VIII, X), normal PTT, normal platelet counts, negative ethanol gelation test (fibrin monomers) were found as well as a prolongation of throm...

journal_title：Thrombosis and haemostasis

authors： Andrassy K,Weischedel E,Ritz E,Andrassy T

更新日期：1976-08-31 00:00:00

abstract：:A four-decade clinical experience and recent evidence from randomised controlled studies definitively recognised primary prophylaxis, i.e. the regular infusion of factor concentrates started after the first haemarthrosis and/or before the age of two years, as the first-choice treatment in children with severe haemophi...

journal_title：Thrombosis and haemostasis

authors： Coppola A,Franchini M,Tagliaferri A

更新日期：2009-04-01 00:00:00

abstract：:Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of allogeneic hematopoietic cell transplantation (HCT). We hypothesized that pretransplant genetic susceptibility is evident in adult TA-TMA and further investigated the association of TMA-associated variants with clinical out...

journal_title：Thrombosis and haemostasis

authors： Gavriilaki E,Touloumenidou T,Sakellari I,Batsis I,Mallouri D,Psomopoulos F,Tsagiopoulou M,Koutra M,Yannaki E,Papalexandri A,Taylor P,Nikolousis E,Stamouli M,Holbro A,Baltadakis I,Liga M,Spyridonidis A,Tsirigotis P,Cha

更新日期：2020-04-01 00:00:00

abstract：:The burden of disease in haemophilia patients has wide ranging implications for the family and to society. There is evidence that having a current inhibitor increases the risk of morbidity and mortality. Morbidity is increased by the inability to treat adequately and its consequent disabilities, which then equates to ...

journal_title：Thrombosis and haemostasis

authors： Walsh CE,Jiménez-Yuste V,Auerswald G,Grancha S

更新日期：2016-08-31 00:00:00

abstract：:Thirty-one individuals from 18 unrelated families with antithrombin deficiency have been identified as having a single point mutation within codon 384 (13268 GCA-->TCA) resulting in an alanine to serine substitution. Six families (11 individuals) were identified by the screening of individuals with thromboembolic dise...

journal_title：Thrombosis and haemostasis

authors： Perry DJ,Daly ME,Tait RC,Walker ID,Brown K,Beauchamp NJ,Preston FE,Gyde H,Harper PL,Carrell RW

更新日期：1998-02-01 00:00:00

abstract：:Two polymorphisms in the endothelial protein C receptor (EPCR) gene, 4600A/G and 4678G/C, have been reported to influence the risk of venous thromboembolism (VTE). The objective of this study was to assess whether these polymorphisms modify the risk of VTE in carriers of factor V (FV) Leiden. We genotyped 295 carriers...

journal_title：Thrombosis and haemostasis

authors： Medina P,Navarro S,Estellés A,Vayá A,Bertina RM,España F

更新日期：2005-08-01 00:00:00

abstract：:An abnormal fibrinogen was discovered in the plasma of a clinically asymptomatic woman. This fibrinogen variant was analyzed by high resolution two-dimensional gel electrophoresis and its molecular abnormality established consisting in a slight decrease in molecular mass of the B beta-chains. Analysis of fibrin reveal...

journal_title：Thrombosis and haemostasis

authors： Meyer M,Schellenberg I,Vogel G,Bischoff I

更新日期：1988-04-08 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with chemokine-like functions. MIF is a critical mediator of the host immune and inflammatory response. Dysregulated MIF expression has been demonstrated to contribute to various acute and chronic inflammatory conditions as well as cancer developme...

journal_title：Thrombosis and haemostasis

authors： Asare Y,Schmitt M,Bernhagen J

更新日期：2013-03-01 00:00:00

abstract：:Platelet activation may contribute to the increased risk of thrombotic complications in patients with antiphospholipid antibodies (aPL). The increased urinary excretion of 11-dehydro-thromboxane B2 (11-DH-TXB2) reported in patients with lupus anticoagulant (LA) and/or anticardiolipin antibodies (aCL) reflects in vivo ...

journal_title：Thrombosis and haemostasis

authors： Forastiero R,Martinuzzo M,Carreras LO,Maclouf J

更新日期：1998-01-01 00:00:00

abstract：:Autoantibodies to the zwitterionic phospholipid (PL), phosphatidylethanolamine (PE) have been described in patients with thrombotic diseases. Recently, we reported that many antiphosphatidylethanolamine antibodies (aPE) are not specific for PE per se, but are directed to plasma proteins which can bind PE, for example,...

journal_title：Thrombosis and haemostasis

authors： Sugi T,Mclntyre JA

更新日期：1996-09-01 00:00:00

abstract：:The in vitro effect of nifedipine, a calcium channel blocker of the dihydropyridine (DHP) type, on platelet aggregation was reinvestigated considering especially the capability of platelets to form endogenous nitric oxide (NO). We studied the dose-dependent antiaggregatory property of nifedipine in porcine platelet ri...

journal_title：Thrombosis and haemostasis

authors： Berkels R,Klaus W,Boller M,Rösen R

更新日期：1994-08-01 00:00:00

abstract：:Thrombolytic therapy has become the mainstay of treatment for acute transmural myocardial infarction. Present fibrinolytic regimens have a number of shortcomings, including the failure to induce early and sustained reperfusion in as many as 40-50% of the patients, and to prevent reocclusion in another 10-20% of the pa...

journal_title：Thrombosis and haemostasis

authors： Pislaru SV,Van de Werf F

更新日期：1999-09-01 00:00:00

abstract：:Causative mutations in the factor VIII gene of seven unrelated patients with severe haemophilia A were identified using the mutation screening procedure conformation sensitive gel electrophoresis (1) and characterised by direct sequencing. Female family members of all patients had requested either carrier status deter...

journal_title：Thrombosis and haemostasis

authors： Williams IJ,Abuzenadah A,Winship PR,Preston FE,Dolan G,Wright J,Peake IR,Goodeve AC

更新日期：1998-04-01 00:00:00

abstract：:Platelet behaviour was studied throughout pregnancy in a group of women who remained normotensive and a group with essential hypertension (EHT). Women who developed pregnancy-induced hypertension (PIH) were also studied together with a group of non-pregnant female controls. We determined the sensitivity of platelets t...

journal_title：Thrombosis and haemostasis

authors： Morrison R,Crawford J,MacPherson M,Heptinstall S

更新日期：1985-10-30 00:00:00

abstract：:Congenital afibrinogenemia and severe hypofibrinogenemia are severe bleeding disorders characterized by either undetectable or very low levels of fibrinogen in patients' plasma and platelets. A majority of the reported cases are caused by mutations in the fibrinogen Aalpha chain. In this study, we identified a genetic...

journal_title：Thrombosis and haemostasis

authors： Xu X,Wu J,Zhai Z,Zhou R,Wang X,Wang H,Ding K,Sun Z,Ni H

更新日期：2006-06-01 00:00:00

abstract：:Endotoxin (LPS) and interleukin-1 beta (IL-1 beta) increased in a dose-dependent manner the expression of tissue factor, an ubiquitous membrane-anchored glycoprotein that initiates blood coagulation at the surface of human umbilical vein endothelial cells (HUVEC and human peripheral blood mononuclear cells (PBMC). Ech...

journal_title：Thrombosis and haemostasis

authors： Herbert JM,Lalé A,Pereillo JM,Derocq JM,Casellas P

更新日期：1996-02-01 00:00:00

abstract：:Cellular adhesion molecules also known as selectins promote recruitment of inflammatory cells into the arterial wall where they interact with lipid particles leading subsequently to plaque formation. The intercellular adhesion molecule-1 (ICAM-1), the vascular cell adhesion molecule-1 (VCAM-1) and the endothelial-leuk...

journal_title：Thrombosis and haemostasis

authors： Hoke M,Winter MP,Wagner O,Exner M,Schillinger M,Arnold Z,Mlekusch W,Maurer G,Koppensteiner R,Minar E,Goliasch G

更新日期：2015-08-31 00:00:00

abstract：:Adjunctive use of phosphodiesterase (PDE) inhibitor can enhance antiplatelet and vasoprotective properties in patients with cardiovascular disease. The aim of this study was to evaluate the impact of PDE5 inhibitor dipyridamole on platelet function in stented patients with high platelet reactivity (HPR) during dual an...

journal_title：Thrombosis and haemostasis

authors： Park Y,Jeong YH,Tantry US,Ahn JH,Kim KH,Koh JS,Park JR,Hwang SJ,Kwak CH,Hwang JY,Gurbel PA

更新日期：2014-12-01 00:00:00

abstract：:Multiple clinical trials have proven that thrombolytic therapy is an effective treatment for acute myocardial infarction. Spontaneous intracranial hemorrhage (ICH) occurs in a small percentage of patients as a result of the treatment. The etiology of the ICH is unknown and there is currently no established experimenta...

journal_title：Thrombosis and haemostasis

authors： Paoni NF,Steinmetz HG,Gillett N,Refino CJ,Badillo JM,Bunting S

更新日期：1996-05-01 00:00:00

abstract：:The structural determinants of lipopolysaccharide required for the induction of tissue factor in human umbilical vein endothelial cells were studied. Intact lipid A was essential for the induction of tissue factor whereas the incomplete lipid A precursors lipid IVA and lipid X, as well as monophosphoryl lipid A and ac...

journal_title：Thrombosis and haemostasis

authors： Moldow CF,Bach RR,Staskus K,Rick PD

更新日期：1993-10-18 00:00:00

abstract：:We have evaluated the effect of plasminogen activators (t-PA and urokinase) on an experimental model of disseminated intravascular coagulation (DIC) in rabbits by injection of 20 micrograms/kg/h of E. coli lipopolysaccharide during 6 h t-PA (0.2 mg/kg and 0.7 mg/kg), urokinase (3000 U/kg/h) and saline (control) were g...

journal_title：Thrombosis and haemostasis

authors： Paloma MJ,Páramo JA,Rocha E

更新日期：1995-12-01 00:00:00

abstract：:The core protein components of the plasminogen activator (PA) system are two plasminogen activators, two plasminogen activator inhibitors and a urokinase type plasminogen activator-specific cell surface receptor. Various types of biological regulation are exerted through the interplay of these components mutually and ...

journal_title：Thrombosis and haemostasis

authors： Nagamine Y,Medcalf RL,Muñoz-Cánoves P

更新日期：2005-04-01 00:00:00

abstract：:Plasminogen activator inhibitor type-1 (PAI-1) is a physiologic modulator of the fibrinolytic system. We have shown previously that PAI-1 biosynthesis in cultured cells depends on several factors in serum. Because platelets are richly endowed with specific growth factors and because the release reaction is an integral...

journal_title：Thrombosis and haemostasis

authors： Hopkins WE,Westerhausen DR,Fujii S,Billadello JJ,Sobel BE

更新日期：1991-08-01 00:00:00

abstract：:There is an increased number of in vitro evidence that angiotensin II (Ang II) may promote thrombosis. However there are no in vivo experiments exploring the effect of Ang II on thrombus formation. In the present study we have investigated the influence of Ang II on venous thrombosis in renovascular hypertensive rats....

journal_title：Thrombosis and haemostasis

authors： Mogielnicki A,Chabielska E,Pawlak R,Szemraj J,Buczko W

更新日期：2005-06-01 00:00:00

abstract：:A factor VIII inhibitor has been found in a patient with an unusual combination of factor VIII-related properties. The inhibitor is directed specifically against the clotting activity (VIII:C) of the factor VIII complex. It behaves in a similar fashion to high responding inhibitors of factor VIII seen in haemophilia A...

journal_title：Thrombosis and haemostasis

authors： Taylor LD,Dean FL,Tiedemann K,Ekert H

更新日期：1986-04-30 00:00:00

abstract：:Tissue factor (TF) is the primary initiator of the coagulation cascade and is thought to play a key role in the generation of arterial thrombosis. Recent studies have suggested that TF mediates inflammatory processes in the arterial wall and may be an important regulator of intimal hyperplasia. We have employed geneti...

journal_title：Thrombosis and haemostasis

authors： Pyo RT,Sato Y,Mackman N,Taubman MB

更新日期：2004-09-01 00:00:00

abstract：:Factor VIII procoagulant activity (F VIII:C) and factor VIII related antigen (F VIII R: Ag) were investigated in 35 patients with Argentine hemorrhagic fever. Since the results obtained in the three clinical forms of the disease were not significantly different, they were tabulated altogether. F VIII:C was low in earl...

journal_title：Thrombosis and haemostasis

authors： Molinas FC,Maiztegui JI

更新日期：1981-08-28 00:00:00

abstract：:To investigate pituitary effects on the vitamin K-dependent coagulation factors, female rats were hypophysectomized (hypox) and treated with growth hormone (GH), cortisone, thyroxine, vitamin K, or saline. After 11 days of treatment, the prothrombin time, platelet count, and factors II, VII, IX, and X were determined....

journal_title：Thrombosis and haemostasis

authors： Sävendahl LS,Grankvist K,Engström KG

更新日期：1995-04-01 00:00:00