Abolished phosphaturic response to parathormone in adult patients with Fahr disease and its restoration after propranolol administration.

Abstract:

:The similar localization of intracranial calcification in hypoparathyroidism and in Fahr disease without parathyroid gland disorder suggests that in these two disorders the pathomechanism of calcium phosphate deposition in the brain may be similar. It may be that in Fahr disease some factors, such as chronic respiratory alkalosis, could lead to hypoparathyroidism-like changes in the brain tissue. Abolition of the phosphaturic response to parathormone (PTH) was recently demonstrated in acute experimental hypocapnia. In three adult patients with Fahr disease, a tendency towards compensatory respiratory alkalosis and arterial hypocapnia was found. The parathormone test revealed a marked decrease in phosphaturia response to PTH, but normal cAMP response. In one patient, the parathormone test was repeated during propranolol administration and showed a considerable improvement in the phosphaturic response to parathormone. It is postulated that chronic hyperventilation and hypocapnia as well as phosphaturic resistance to PTH, intracellular increase of phosphate concentration and development of hypoparathyroidism-like intracranial calcification in patients with Fahr disease could all be caused by disturbance of adrenergic receptors and their relationship to PTH receptors.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Pronicka E,Kulczycki J,Rowińska E,Kuran W

doi

10.1007/BF00314315

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

185-7

issue

3

eissn

0340-5354

issn

1432-1459

journal_volume

235

pub_type

杂志文章
  • Detection of anterior horn lesions by MRI in central European tick-borne encephalomyelitis.

    abstract::We report a case of central European tick-borne encephalitis with cervical myelitis presenting clinically as a lower motor neuron syndrome of the upper limbs with proximal asymmetrical pareses and atrophies. There were no sensory deficits nor signs of lesions of the spinal pathways or signs of encephalitis or meningit...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150050537

    authors: Beer S,Brune N,Kesselring J

    更新日期:1999-12-01 00:00:00

  • History of the 'geste antagoniste' sign in cervical dystonia.

    abstract::The geste antagoniste is a voluntary maneuver that temporarily reduces the severity of dystonic posture or movements. It is a classical feature of focal and particularly cervical dystonia. However, the precise historical aspects of geste antagoniste still remain obscure. The goals of this review were (1) to clarify th...

    journal_title:Journal of neurology

    pub_type: 历史文章,杂志文章

    doi:10.1007/s00415-011-6380-7

    authors: Poisson A,Krack P,Thobois S,Loiraud C,Serra G,Vial C,Broussolle E

    更新日期:2012-08-01 00:00:00

  • Current issues in antiplatelet therapy for stroke prevention: the importance of stroke subtypes and differences between stroke and MI patients.

    abstract::Ischaemic stroke, the most common type of stroke, is classified into three main subtypes: large-vessel disease, lacunar or small-vessel disease, and cardioembolic; two further subtypes include a determined aetiology of "other" and cryptogenic. Although a substantial amount of literature exists concerning current guide...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-010-5667-4

    authors: Kirshner HS

    更新日期:2010-11-01 00:00:00

  • Comparison of CMT1A and CMT2: similarities and differences.

    abstract::To evaluate the clinical and electrophysiological similarities and differences between two large groups of patients with Charcot-Marie-Tooth disease, i.e. CMT1A and CMT2, we performed a post hoc comparison of clinical and electrophysiological data. Most CMT1A and CMT2 patients had the classical CMT phenotype. Age of o...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-006-0260-6

    authors: Bienfait HM,Verhamme C,van Schaik IN,Koelman JH,de Visser BW,de Haan RJ,Baas F,van Engelen BG,de Visser M

    更新日期:2006-12-01 00:00:00

  • Is increased spinal nociception another hallmark for Parkinson's disease?

    abstract::Augmented spinal nociception during the "off" phase has been observed early in Parkinson's disease further increasing with disease duration. To find out whether increased spinal nociception represents a premotor feature, experimental pain sensitivity was assessed in idiopathic REM-sleep behavior disorder (IRBD) patien...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-016-8390-y

    authors: Boura E,Stamelou M,Vadasz D,Ries V,Unger MM,Kägi G,Oertel WH,Möller JC,Mylius V

    更新日期:2017-03-01 00:00:00

  • COVID-19 in children with neuromuscular disorders.

    abstract:OBJECTIVE:Children with neuromuscular disorders have been assumed to be a particularly vulnerable population since the beginning of COVID-19. Although this is a plausible hypothesis, there is no evidence that complications or mortality rates in neuromuscular patients are higher than in the general population. The aim o...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-10339-y

    authors: Natera-de Benito D,Aguilera-Albesa S,Costa-Comellas L,García-Romero M,Miranda-Herrero MC,Rúbies Olives J,García-Campos Ó,Martínez Del Val E,Martinez Garcia MJ,Medina Martínez I,Cancho-Candela R,Fernandez-Garcia MA,Pascual-Pascual

    更新日期:2021-01-02 00:00:00

  • Acetylcholine esterase inhibitor donepezil improves dynamic cerebrovascular regulation in Alzheimer patients.

    abstract:BACKGROUND:Alzheimer's disease (AD) leads to a degeneration of the nucleus basalis of Meynert and thus to decreased cholinergic tonus in the brain. The transcription of endothelial nitric oxide synthase depends on an adequate cholinergic innervation of microvessels and vasoregulative abnormalities have been reported in...

    journal_title:Journal of neurology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00415-005-0926-5

    authors: Rosengarten B,Paulsen S,Molnar S,Kaschel R,Gallhofer B,Kaps M

    更新日期:2006-01-01 00:00:00

  • Cerebellar ataxia and congenital disorder of glycosylation Ia (CDG-Ia) with normal routine CDG screening.

    abstract::Cerebellar ataxia can have many genetic causes among which are the congenital disorders of glycosylation type I (CDG-I). In this group of disorders, a multisystem phenotype is generally observed including the involvement of many organs, the endocrine, hematologic and central nervous systems. A few cases of CDG-Ia have...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-007-0546-3

    authors: Vermeer S,Kremer HP,Leijten QH,Scheffer H,Matthijs G,Wevers RA,Knoers NA,Morava E,Lefeber DJ

    更新日期:2007-10-01 00:00:00

  • Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2.

    abstract::Advances in molecular biology have resulted in novel therapy for neurofibromatosis 2-related (NF2) tumours, highlighting the need for robust outcome measures. The disease-focused NF2 impact on quality of life (NFTI-QOL) patient questionnaire was assessed as an outcome measure for treatment in a multi-centre study. NFT...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-014-7303-1

    authors: Ferner RE,Shaw A,Evans DG,McAleer D,Halliday D,Parry A,Raymond FL,Durie-Gair J,Hanemann CO,Hornigold R,Axon P,Golding JF

    更新日期:2014-05-01 00:00:00

  • Frequency of nocturnal sudden death in patients with multiple system atrophy.

    abstract::Sudden death has been reported in patients with multiple system atrophy (MSA), although the frequency of this event has not been well delineated. We investigated the frequency and potential causes of sudden death in patients with MSA. During the 5-year observation period, 10 of 45 patients with probable MSA died. The ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-008-0941-4

    authors: Shimohata T,Ozawa T,Nakayama H,Tomita M,Shinoda H,Nishizawa M

    更新日期:2008-10-01 00:00:00

  • Investigation of unilateral facial weakness: magnetic stimulation of the proximal facial nerve and of the face-associated motor cortex.

    abstract::Twenty-four patients with unilateral facial weakness of various aetiologies were investigated using a magnetic stimulator to stimulate the proximal segment of the facial nerve directly (short latency response) and also to activate the facial motoneurons bilaterally via corticonuclear pathways by placing the stimulatin...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314405

    authors: Meyer BU,Britton TC,Benecke R

    更新日期:1989-02-01 00:00:00

  • Quantitative MR analyses of the hippocampus: unspecific metabolic changes in aging.

    abstract::The age-related structural changes of the human hippocampus are not entirely understood. The goal of the present investigation was to understand better the nature of age-related hippocampal changes by a comparative MR-analysis of four complementary aspects of hippocampal integrity: total volume, metabolite concentrati...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-004-0540-y

    authors: Szentkuti A,Guderian S,Schiltz K,Kaufmann J,Münte TF,Heinze HJ,Düzel E

    更新日期:2004-11-01 00:00:00

  • Seasonal variation in multiple sclerosis relapse.

    abstract::Relapses are a characteristic clinical feature of multiple sclerosis (MS), but an appreciation of factors that cause them remains elusive. In this study, we have examined seasonal variation of relapse in a large population-based MS cohort and correlated observed patterns with age, sex, disease course, and climatic fac...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-017-8485-0

    authors: Harding K,Tilling K,MacIver C,Willis M,Joseph F,Ingram G,Hirst C,Wardle M,Pickersgill T,Ben-Shlomo Y,Robertson N

    更新日期:2017-06-01 00:00:00

  • Patterns of cortical activity differ in ALS patients with limb and/or bulbar involvement depending on motor tasks.

    abstract::Functional magnetic resonance imaging (fMRI) of hand movements in amyotrophic lateral sclerosis (ALS) has repeatedly demonstrated increased activation in cortical and subcortical areas, whereas a single study has suggested decreased rather than increased activations for tongue movements in patients with bulbar involve...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-010-5842-7

    authors: Kollewe K,Münte TF,Samii A,Dengler R,Petri S,Mohammadi B

    更新日期:2011-05-01 00:00:00

  • Ischaemic supratentorial stroke: angiographic findings in patients examined in the very early phase.

    abstract::Eighty patients were studied by angiography within 6 h of an ischaemic stroke. Angiography was carried out with digital equipment and was usually limited to the vascular territory responsible for the neurological deficits. In 12 of 19 patients with internal carotid occlusion, the contralateral side was also studied. T...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314376

    authors: Bozzao L,Fantozzi LM,Bastianello S,Bozzao A,Argentino C,Lenzi GL,Fieschi C

    更新日期:1989-09-01 00:00:00

  • Safety and outcomes of intravenous thrombolysis in dissection-related ischemic stroke: an international multicenter study and comprehensive meta-analysis of reported case series.

    abstract::The safety and efficacy of intravenous thrombolysis (IVT) in dissection-related ischemic stroke (DRIS) has not been established. We sought to determine safety and recovery rates of IVT in DRIS using prospective, international, multicenter data and by conducting a comprehensive meta-analysis of reported case series. We...

    journal_title:Journal of neurology

    pub_type: 杂志文章,meta分析,多中心研究

    doi:10.1007/s00415-015-7829-x

    authors: Tsivgoulis G,Zand R,Katsanos AH,Sharma VK,Goyal N,Krogias C,Safouris A,Vadikolias K,Voumvourakis K,Alexandrov AW,Malkoff MD,Alexandrov AV

    更新日期:2015-09-01 00:00:00

  • The spirochetal etiology of lymphocytic meningoradiculitis of Bannwarth (Bannwarth's syndrome).

    abstract::In all the sera of four patients with meningoradiculitis of Bannwarth admitted to the neurological department of the University Clinic Grosshadern in Munich in 1983, we found antibodies against Ixodes dammini spirochetes. In three patients antibodies were also present in the CSF. In one patient, we isolated spirochete...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313682

    authors: Pfister HW,Einhäupl K,Preac-Mursic V,Wilske B,Schierz G

    更新日期:1984-01-01 00:00:00

  • Neuro-ophthalmology update.

    abstract::This review summarizes the most relevant articles from the field of neuro-ophthalmology published in the Journal of Neurology from January 2012 to July 2013. With the advent of video-oculography, several articles describe new applications for eye movement recordings as a diagnostic tool for a wide range of disorders. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-013-7105-x

    authors: Weber KP,Straumann D

    更新日期:2014-07-01 00:00:00

  • Schwartz-Jampel syndrome associated with von Willebrand's disease.

    abstract::We report a very rare case of Schwartz-Jampel syndrome associated with von Willebrand's disease. This association might be coincidental because of the different modes of inheritance of the two disorders. However, we speculate that there might be some link between the two disorders, for example in the locus of the affe...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314041

    authors: Kuriyama M,Shinmyozu K,Osame M,Kawahira M,Igata A

    更新日期:1985-01-01 00:00:00

  • Early diagnosis of dementia: which tests are indicated? What are their costs?

    abstract::Dementia is reversible in a minority of patients, and these should be diagnosed but without subjecting the majority with irreversible disease to an excessive set of investigations. Should a battery of ancillary investigations be performed routinely in dementia? Or can these tests be carried out as clinically indicated...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s004150050311

    authors: van Crevel H,van Gool WA,Walstra GJ

    更新日期:1999-02-01 00:00:00

  • Familial Sneddon's syndrome.

    abstract::We report the familial occurrence and apparent autosomal dominant inheritance of Sneddon's syndrome with variable clinical expression. The proband, a 40-year-old woman, presented with livedo reticularis and progressive neurological deterioration following a stroke. The diagnosis was confirmed by cerebral angiogram and...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00936890

    authors: Lossos A,Ben-Hur T,Ben-Nariah Z,Enk C,Gomori M,Soffer D

    更新日期:1995-02-01 00:00:00

  • Changes of circadian blood pressure patterns and cardiovascular parameters indicate lateralization of sympathetic activation following hemispheric brain infarction.

    abstract::The effects of left- and right-sided hemispheric brain infarction on variability in circadian blood pressure and cardiovascular measures were investigated in 35 patients to test for asymmetry of the sympathetic consequences of stroke. No significant differences regarding age, size of infarction or extent and frequency...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00878874

    authors: Sander D,Klingelhöfer J

    更新日期:1995-05-01 00:00:00

  • Clinicopathological features of multiple mononeuropathy associated with systemic lupus erythematosus: a multicenter study.

    abstract::Multiple mononeuropathy (MM) occurs rarely during systemic lupus erythematosus (SLE) but may lead to major disability. The aim of this study was to investigate the clinic-pathological presentations of MM during SLE, as well as long-term outcomes. We conducted a multicentric retrospective study that included patients r...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-017-8519-7

    authors: Rivière E,Cohen Aubart F,Maisonobe T,Maurier F,Richez C,Gombert B,Gousseff M,Adoue D,Mathian A,Hié M,Haroche J,Amoura Z

    更新日期:2017-06-01 00:00:00

  • Association between polymorphism in the promoter region of Interleukin 6 (-174 G/C) and risk of Alzheimer's disease: a meta-analysis.

    abstract::Studies of the relationship between Alzheimer's disease (AD) and polymorphism in the promoter region of Interleukin 6 (IL-6) -174 G/C have reported inconsistent results. To assess the association between IL-6 -174 G/C promoter polymorphism and AD risk, a meta-analysis containing 3,101 AD cases and 3,860 controls from ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00415-011-6164-0

    authors: Dai L,Liu D,Guo H,Wang Y,Bai Y

    更新日期:2012-03-01 00:00:00

  • Effect of levodopa on handwriting tasks of different complexity in Parkinson's disease: a kinematic study.

    abstract::Levodopa treatment does improve Parkinson's disease (PD) dysgraphia, but previous research is not in agreement about which aspects are most responsive. This study investigated the effect of levodopa on the kinematics of writing. Twenty-four patients with PD of less than 10 years duration and 25 age-matched controls we...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-019-09268-2

    authors: Zham P,Kumar D,Viswanthan R,Wong K,Nagao KJ,Arjunan SP,Raghav S,Kempster P

    更新日期:2019-06-01 00:00:00

  • What is pathological with gaze shift fragmentation in Parkinson's disease?

    abstract::Oculomotor dysfunction in Parkinson's disease (PD) is mainly characterized by a fragmentation of memory-guided gaze shifts (target is reached by several hypometric saccades). Since this phenomenon can also be observed in normal subjects, we scrutinized its pathophysiological significance in PD patients. We recorded ho...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-002-0691-7

    authors: Kimmig H,Haussmann K,Mergner T,Lücking CH

    更新日期:2002-06-01 00:00:00

  • Sexuality in patients with amyotrophic lateral sclerosis and their partners.

    abstract::Sexuality in patients with amyotrophic lateral sclerosis (ALS) has received little attention so far. Although sexual function is not directly affected by the disease process, several patients have reported problems within their sexual relationship. We performed a questionnaire survey to ascertain the extent and clinic...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-004-0351-1

    authors: Wasner M,Bold U,Vollmer TC,Borasio GD

    更新日期:2004-04-01 00:00:00

  • 1H MR spectroscopy of gray and white matter in carbon monoxide poisoning.

    abstract::Carbon monoxide (CO) intoxication leads to acute and chronic neurological deficits, but little is known about the specific noxious mechanisms. (1)H magnetic resonance spectroscopy (MRS) may allow insight into the pathophysiology of CO poisoning by monitoring neurochemical disturbances, yet only limited information is ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-009-5057-y

    authors: Kondziella D,Danielsen ER,Hansen K,Thomsen C,Jansen EC,Arlien-Soeborg P

    更新日期:2009-06-01 00:00:00

  • An unusual form of measles meningoencephalitis. A report of two cases.

    abstract::Two patients are reported with a chronic progressive illness characterized by dementia, ataxia and spasticity. There were no myoclonic jerks and both had normal electroencephalograms (EEG). Pathological findings in three brain biopsies were those of viral meningoencephalitis with perivenous demyelination. Serological ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313048

    authors: Derakhshan I,Shafii A,Lotfi J,Abbassioun K,Scillian JJ

    更新日期:1979-09-01 00:00:00

  • Factors influencing work retention for people with multiple sclerosis: cross-sectional studies using qualitative and quantitative methods.

    abstract:OBJECTIVE:To identify factors that impact on the ability of patients with multiple sclerosis (MS) to remain in work in order to make recommendations for future clinical management. METHODS:Cross-sectional studies using qualitative (phase one) and quantitative (phase two) methods. In phase one, 62 patients were intervi...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-005-0765-4

    authors: O'Connor RJ,Cano SJ,Ramió i Torrentà L,Thompson AJ,Playford ED

    更新日期:2005-08-01 00:00:00