Abstract:
:The delta-endotoxin produced by Bacillus thuringiensis ssp. entomocidus induced the release of encapsulated [14C]sucrose from reverse-phase vesicles composed of phosphatidylcholine and cholesterol. No such release was detected when the phospholipid component of the vesicles was either phosphatidylethanolamine, phosphatidylglycerol, or sphingomyelin. The toxin-induced release was competitively inhibited by negatively charged organic ions while positively charged organic ions, apart from choline chloride, had no such effect. The existence of a polar head group in the phospholipid as well as intermolecular hydrogen bonding at the membrane surface, was found to be of major importance in the toxin-liposome interaction.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Yunovitz H,Yawetz Adoi
10.1016/0014-5793(88)80651-3subject
Has Abstractpub_date
1988-03-28 00:00:00pages
105-8issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(88)80651-3journal_volume
230pub_type
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