The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A.

abstract：:Estimating the potential distribution of invasive species has been primarily achieved by employing species distribution models (SDM). Recently introduced joint species distribution models (JSDM) that include species interactions are expected to improve model output. Here we compare the predictive ability of SDM and JS...

journal_title：Scientific reports

authors： Magory Cohen T,Dor R

更新日期：2019-11-01 00:00:00

abstract：:NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to describe differences i...

journal_title：Scientific reports

authors： Nava M,Dutta P,Farias-Eisner R,Vadgama JV,Wu Y

更新日期：2019-03-26 00:00:00

abstract：:The ubiquitin-proteasomal degradation mechanism has gained the attention over the past decade. The E2 ubiquitin conjugating enzymes are the crucial part of ubiquitination mechanism and they are believed to hold imperative association for plant development. It accepts ubiquitin from the E1 enzyme and interacts with the...

journal_title：Scientific reports

authors： Sharma B,Bhatt TK

更新日期：2017-08-17 00:00:00

abstract：:Sense of body ownership and body representation are fundamental parts of human consciousness, but the contribution of the visual modality to their development remains unclear. We tested congenitally and late blind adults on a somatosensory version of the rubber hand illusion, and on the Aristotle illusion, in which si...

journal_title：Scientific reports

authors： Nava E,Steiger T,Röder B

更新日期：2014-10-23 00:00:00

abstract：:Within year individual variation in the timing of seasonal reproduction within wild bird populations in highly seasonal environments can be pronounced, but the molecular and physiological mechanisms responsible for this variation are unclear. We investigated the relationship between Clock gene poly-Q length, activatio...

journal_title：Scientific reports

authors： Zhang S,Xu X,Wang W,Yang W,Liang W

更新日期：2017-11-03 00:00:00

abstract：:Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify the individual caspases critical...

journal_title：Scientific reports

authors： Kratochvílová A,Veselá B,Ledvina V,Švandová E,Klepárník K,Dadáková K,Beneš P,Matalová E

更新日期：2020-05-04 00:00:00

abstract：:Intuitively, deriving meaning from an abstract image is a uniquely human, idiosyncratic experience. Here we show that, despite having no universally recognised lexical association, abstract images spontaneously elicit specific concepts conveyed by words, with a consistency akin to that of concrete images. We presented...

journal_title：Scientific reports

authors： Kuipers JR,Jones MW,Thierry G

更新日期：2018-05-08 00:00:00

abstract：:A significant advantage of a graphene biosensor is that it inherently represents a continuum of independent and aligned sensor-units. We demonstrate a nanoscale version of a micro-physiometer - a device that measures cellular metabolic activity from the local acidification rate. Graphene functions as a matrix of indep...

journal_title：Scientific reports

authors： Paulus GL,Nelson JT,Lee KY,Wang QH,Reuel NF,Grassbaugh BR,Kruss S,Landry MP,Kang JW,Vander Ende E,Zhang J,Mu B,Dasari RR,Opel CF,Wittrup KD,Strano MS

更新日期：2014-10-31 00:00:00

abstract：:Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other genes, which could...

journal_title：Scientific reports

authors： Nakajima K,Kazuno AA,Kelsoe J,Nakanishi M,Takumi T,Kato T

更新日期：2016-10-04 00:00:00

abstract：:Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water deficit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water deficit and ABA induce expression of some RD22-like proteins. This study aimed to evaluate the effect of water deficit and exogenous ABA...

journal_title：Scientific reports

authors： Phillips K,Ludidi N

更新日期：2017-08-18 00:00:00

abstract：:Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the roles of individual regions within more complex asymmetrical cha...

journal_title：Scientific reports

authors： Penny CJ,Rahman T,Sula A,Miles AJ,Wallace BA,Patel S

更新日期：2016-12-12 00:00:00

abstract：:Macrophages play an important role in the inflammatory process that contributes to the development of abdominal aortic aneurysm (AAA). Studies of human and mouse AAA tissue reveal expanded populations of macrophages producing an abundance of pro-inflammatory cytokines, including TNF-α, IL-12p40 and high level of metal...

journal_title：Scientific reports

authors： Yan H,Hu Y,Akk A,Ye K,Bacon J,Pham CTN

更新日期：2019-07-18 00:00:00

abstract：:The stochastic tunneling-basin hopping method (STUN-BH) was utilized to obtain the most stable peptide S7 configuration (Ac-Ser-Ser-Phe-Pro-Gln-Pro-Asn-CONH2) adsorbed on Au(111) facet. After the most stable S7 configuration was found, molecular dynamics (MD) simulation was conducted to investigate the thermal stabili...

journal_title：Scientific reports

authors： Lin CH,Ju SP,Su JW,Li DE

更新日期：2020-02-07 00:00:00

abstract：:Almost 150 years after the first identification of Neandertal skeletal material, the cognitive and symbolic abilities of these populations remain a subject of intense debate. We present 99 new Neandertal remains from the Troisième caverne of Goyet (Belgium) dated to 40,500-45,500 calBP. The remains were identified thr...

journal_title：Scientific reports

authors： Rougier H,Crevecoeur I,Beauval C,Posth C,Flas D,Wißing C,Furtwängler A,Germonpré M,Gómez-Olivencia A,Semal P,van der Plicht J,Bocherens H,Krause J

更新日期：2016-07-06 00:00:00

abstract：:Central nervous system-specific proteins (CSPs), transported across the damaged blood-brain-barrier (BBB) to cerebrospinal fluid (CSF) and blood (serum), might be promising diagnostic, prognostic and predictive protein biomarkers of disease in individual multiple sclerosis (MS) patients because they are not expected t...

journal_title：Scientific reports

authors： Raphael I,Mahesula S,Purkar A,Black D,Catala A,Gelfond JA,Forsthuber TG,Haskins WE

更新日期：2014-09-03 00:00:00

abstract：:Tinnitus (phantom auditory perception associated with hearing loss) can seriously affect wellbeing. Its neural substrate is unknown however it has been linked with abnormal activity in auditory pathways. Though no cure currently exists, repetitive transcranial magnetic stimulation (rTMS) has been shown to reduce tinni...

journal_title：Scientific reports

authors： Mulders WH,Vooys V,Makowiecki K,Tang AD,Rodger J

更新日期：2016-12-01 00:00:00

abstract：:In this retrospective study, we investigated the impact of diabetes mellitus (DM) on patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). We analyzed the demographic and clinical characteristics, treatment tolerance, and toxicities of patients with HNC undergoing primary or adjuvant...

journal_title：Scientific reports

authors： Kuo HC,Chang PH,Wang CH

更新日期：2020-05-07 00:00:00

abstract：:The use of micro- and nanodevices as multifunctional systems for biomedical applications has experienced an exponential growth during the past decades. Although a large number of studies have focused on the design and fabrication of new micro- and nanosystems capable of developing multiple functions, a deeper understa...

journal_title：Scientific reports

authors： Patiño T,Soriano J,Barrios L,Ibáñez E,Nogués C

更新日期：2015-06-12 00:00:00

abstract：:Accurate intraocular lens (IOL) power calculation is always a challenge in ophthalmology, and unoptimized process may lead to inaccurate refractive outcomes. Quality control circle (QCC) has shown its success in many fields as a process management tool. However, its efficacy in ophthalmology remains unclear. Here we u...

journal_title：Scientific reports

authors： Lin L,Chang P,Xie J,Li Z,Zhang H,Lu F,Zhao YE

更新日期：2017-11-01 00:00:00

abstract：:Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in t...

journal_title：Scientific reports

authors： Sreenath TL,Macalindong SS,Mikhalkevich N,Sharad S,Mohamed A,Young D,Borbiev T,Xavier C,Gupta R,Jamal M,Babcock K,Tan SH,Nevalainen MT,Dobi A,Petrovics G,Sesterhenn IA,Rosner IL,Bieberich CJ,Nelson P,Vasioukhin V,

更新日期：2017-04-24 00:00:00

abstract：:Because of the lack of cell wall, Micoplasma species require a fine control of membrane fluidity and integrity. mg517 is an essential gene of Mycoplasma genitalium responsible for the biosynthesis of membrane glycoglycerolipids. It encodes for a unique glycosyltransferase (MG517) with processive activity, transferring...

journal_title：Scientific reports

authors： Romero-García J,Biarnés X,Planas A

更新日期：2019-05-08 00:00:00

abstract：:The strong adhesion of sub-micron sized particles to surfaces is a nuisance, both for removing contaminating colloids from surfaces and for conscious manipulation of particles to create and test novel micro/nano-scale assemblies. The obvious idea of using detergents to ease these processes suffers from a lack of contr...

journal_title：Scientific reports

authors： Feldmann D,Maduar SR,Santer M,Lomadze N,Vinogradova OI,Santer S

更新日期：2016-11-03 00:00:00

abstract：:Although the perception of faces depends on low-level neuronal processes, it is also affected by high-level social processes. Faces from a social in-group, such as people of a similar age, receive more in-depth processing and are processed holistically. To explore whether own-age biases affect subconscious face percep...

journal_title：Scientific reports

authors： Nicholls MER,Churches O,Loetscher T

更新日期：2018-08-23 00:00:00

abstract：:Ballooning degeneration (BD) of hepatocytes is a distinguishing histological feature associated with the progression of nonalcoholic fatty liver disease (NAFLD). Under the assumption that NAFLD severity is associated with metabolic-stress we explored the hypothesis that heat shock 27 kDa protein 1 (HSP27), a protein c...

journal_title：Scientific reports

authors： Sookoian S,Castaño GO,Scian R,San Martino J,Pirola CJ

更新日期：2016-03-03 00:00:00

abstract：:Differential vulnerability among motor neuron (MN) subtypes is a fundamental feature of amyotrophic lateral sclerosis (ALS): fast-fatigable (FF) MNs are more vulnerable than fast fatigue-resistant (FR) or slow (S) MNs. The reason for this selective vulnerability remains enigmatic. We report here that the extracellular...

journal_title：Scientific reports

authors： Morisaki Y,Niikura M,Watanabe M,Onishi K,Tanabe S,Moriwaki Y,Okuda T,Ohara S,Murayama S,Takao M,Uchida S,Yamanaka K,Misawa H

更新日期：2016-06-06 00:00:00

abstract：:A. baumannii infections are becoming more and more serious health issues with rapid emerging of multidrug and extremely drug resistant strains, and therefore, there is an urgent need for the development of nonantibiotic-based intervention strategies. This study aimed at identifying whether an outer membrane protein wi...

journal_title：Scientific reports

authors： Huang W,Yao Y,Wang S,Xia Y,Yang X,Long Q,Sun W,Liu C,Li Y,Chu X,Bai H,Yao Y,Ma Y

更新日期：2016-02-08 00:00:00

abstract：:The aim of this study was to identify mRNA targets of dysregulated miRNAs through the integrated analysis of miRNA and mRNA expression profiling in men with normal versus impaired spermatogenesis. The expression of mRNAs and miRNAs in testicular tissues obtained from males with non-obstructive azoospermia (NOA, n = 4)...

journal_title：Scientific reports

authors： Zhuang X,Li Z,Lin H,Gu L,Lin Q,Lu Z,Tzeng CM

更新日期：2015-01-28 00:00:00

abstract：:Despite strengthened antimicrobial therapy, biofilm infections of Acinetobacter baumannii are associated with poor prognosis and limited therapeutic options. Assessing antibiotics on planktonic bacteria can result in failure against biofilm infections. Currently, antibiotics to treat biofilm infections are administere...

journal_title：Scientific reports

authors： Wannigama DL,Hurst C,Pearson L,Saethang T,Singkham-In U,Luk-In S,Storer RJ,Chatsuwan T

更新日期：2019-04-19 00:00:00

abstract：ABSTARCT:Graphene has sparked extensive research interest for its excellent physical properties and its unique potential for application in absorption of electromagnetic waves. However, the processing of stable large-scale graphene and magnetic particles on a micrometer-thick conductive support is a formidable challeng...

journal_title：Scientific reports

authors： Li J,Lu W,Suhr J,Chen H,Xiao JQ,Chou TW

更新日期：2017-05-24 00:00:00

abstract：:Magnetic resonance imaging (MRI) has evolved into an outstandingly versatile diagnostic modality, as it has the ability to non-invasively produce detailed information on a tissue's structure and function. Complementary data is normally obtained in separate measurements, either as contrast-weighted images, which are fa...

journal_title：Scientific reports

authors： Gómez PA,Molina-Romero M,Buonincontri G,Menzel MI,Menze BH

更新日期：2019-06-11 00:00:00