Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers.

abstract：BACKGROUND:Although intralesional methotrexate (MTX) is an effective, nonsurgical treatment of keratoacanthoma (KA), there have not been many reports of on the MTX treatment for KA in Korea. OBJECTIVE:The purpose of this study was to evaluate the clinical efficacy of the intralesional MTX for the treatment of KA in Ko...

journal_title：Annals of dermatology

authors： Yoo MG,Kim IH

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE:To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD...

journal_title：Annals of dermatology

authors： Lim SK,Lim CA,Kwon IS,Im M,Seo YJ,Kim CD,Lee JH,Lee Y

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...

journal_title：Annals of dermatology

authors： Kim HS,Kim TW,Mun JH,Song M,Ko HC,Kim BS,Kim MB

更新日期：2014-08-01 00:00:00

abstract：:Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspect...

journal_title：Annals of dermatology

authors： Kumar S,Sidhu S,Mahajan BB

更新日期：2013-08-01 00:00:00

abstract：:This is the first case report to describe a 44-year-old woman with a history of advanced hepatocellular carcinoma who developed toxic epidermal necrolysis (TEN) clinically after taking 400 mg sorafenib (Nexavar®, BAY 43-9006) and tosufloxacin orally once per day. Both sorafenib and tosufloxacin were eventually discont...

journal_title：Annals of dermatology

authors： Choi MK,Woo HY,Heo J,Cho M,Kim GH,Song GA,Kim MB

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Multiplex polymerase chain reaction (PCR) allows more than two target DNA molecules to be amplified with more than two primers. This method is also useful for detecting various other organisms simultaneously within a single test tube, and the scope of its use has been expanding widely in the field of clinica...

journal_title：Annals of dermatology

authors： Kim JY,Choe YB,Ahn KJ,Lee YW

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE:In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis. METHODS:Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic der...

journal_title：Annals of dermatology

authors： Lee JH,Jeon YJ,Choi JH,Kim HY,Kim TY

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Computer-aided image analysis (CAIA) has been suggested as an effective diagnostic tool for pigmented skin lesions (PSLs), especially melanoma. However, few studies on benign PSLs have been reported. OBJECTIVE:The purpose of this study was to evaluate benign PSLs with our CAIA software and analyze the diffe...

journal_title：Annals of dermatology

authors： Choi JW,Ryu HH,Byun SY,Youn SW

更新日期：2014-06-01 00:00:00

abstract：:Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...

journal_title：Annals of dermatology

authors： Kim GW,Park HJ,Kim HS,Kim SH,Ko HC,Kim BS,Kim MB

更新日期：2011-12-01 00:00:00

abstract：:Entecavir (Baraclude®, Bristol-Myers Squibb) is a potent and selective antiviral agent that has demonstrated efficacy in patients with chronic hepatitis B. The most frequent adverse events attributed to entecavir include increased alanine aminotransferase, upper respiratory tract infection, headache, abdominal pain, c...

journal_title：Annals of dermatology

authors： Yoon J,Park D,Kim C

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Hair follicles undergo cycles of repeated growth and regression. The Wnt pathway plays an important role in the regeneration and differentiation of hair follicles. Sfrp2, a Wnt inhibitor, is involved in the developmental and disease processes of various cells and tissues by modulating the Wnt pathway. OBJEC...

journal_title：Annals of dermatology

authors： Kim BK,Yoon SK

更新日期：2014-02-01 00:00:00

abstract：:Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp. ...

journal_title：Annals of dermatology

authors： Kim MS,Lee JH,Lee WM,Son SJ

更新日期：2010-08-01 00:00:00

abstract：:Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless...

journal_title：Annals of dermatology

authors： Paek JO,Kang HS,Yeo KY,Yu HJ,Kim JS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Angiogenesis is crucial for wound healing and exogenous supplements of the angiogenic growth factors have been known to promote cutaneous wound healing. Angiopoietin (Ang) 1 is a recently discovered angiogenic factor and there have been few studies of its effect on cutaneous wound healing. OBJECTIVE:We exam...

journal_title：Annals of dermatology

authors： Kim YY,Kim YJ,Ku JK,Kim MY,Kim YI,Koh GY,Kim HO,Park YM

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...

journal_title：Annals of dermatology

authors： Zöller N,Valesky E,Hofmann M,Bereiter-Hahn J,Bernd A,Kaufmann R,Meissner M,Kippenberger S

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze...

journal_title：Annals of dermatology

authors： Roh NK,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2016-04-01 00:00:00

abstract：:Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy. The nipple-areola complex (NAC) is an uncommon site for BCC to develop. BCCs in this region display more aggressive behavior and a greater potential to spread than when found i...

journal_title：Annals of dermatology

authors： Jung HJ,Jun JH,Kim HY,Lee SJ,Kim DW,Lee WJ,Jung JH

更新日期：2011-10-01 00:00:00

abstract：:Matridex(R) is an injectable skin filler that's composed of a mixture of cross linked hyaluronic acid and dextranomer particles, and it was recently developed for soft tissue augmentation. To the best of our knowledge, there have been few previous reports on complications associated with Matridex. We report here on a ...

journal_title：Annals of dermatology

authors： Huh SY,Cho S,Kim KH,An JS,Won CH,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2010-02-01 00:00:00

abstract：:Leiomyosarcomas are uncommon malignant smooth muscle tumors, mainly derived from vessels or viscera. Superficial leiomyosarcomas are a rare soft tissue sarcoma arising from the dermis or subcutaneous tissue in the skin. According to tumor origin and location, they are divided into cutaneous and subcutaneous leiomyosar...

journal_title：Annals of dermatology

authors： Lee KC,Kim MS,Choi H,Na CH,Shin BS

更新日期：2013-05-01 00:00:00

abstract：:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...

journal_title：Annals of dermatology

authors： Yoon SY,Kwon HH,Jeon HC,Lee JH,Cho S

更新日期：2011-11-01 00:00:00

abstract：:Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, ...

journal_title：Annals of dermatology

authors： Kim JS,Choi M,Nam CH,Kim JY,Park BC,Kim MH,Hong SP

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...

journal_title：Annals of dermatology

authors： Park JM,Cho HH,Kim WJ,Mun JH,Song M,Kim HS,Ko HC,Kim BS,Kim MB

更新日期：2015-08-01 00:00:00

abstract：:Bowen's disease usually manifests as a slowly enlarging erythematous scaly patch or plaque. An uncommon variant of Bowen's disease showing a verrucous appearance has been reported and a distinct variant with a prominent clear cell change on histopathology, in addition to a verrucous surface change, was also reported. ...

journal_title：Annals of dermatology

authors： Lee DY,Choi KH,Park SH,Lee JY,Yoon TY

更新日期：2017-08-01 00:00:00

abstract：:Nuchal-type fibroma is a rare, benign, fibrous, tumor-like proliferation characterized by dense hypocellular bundles of collagen, with sparsely scattered fibroblasts, interspersed fat tissue, and entrapped nerve fibers. It usually develops in the posterior neck as a solitary, firm, poorly circumscribed, subcutaneous m...

journal_title：Annals of dermatology

authors： Kim DH,Kim TH,Sung NH,Shin H,Lee AY,Lee SH

更新日期：2015-04-01 00:00:00

abstract：:Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...

journal_title：Annals of dermatology

authors： Lee D,Kang JH,Kim SH,Seo JK,Sung HS,Hwang SW

更新日期：2008-09-01 00:00:00

abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...

journal_title：Annals of dermatology

authors： Choi MJ,Kim HS,Kim HO,Song KY,Park YM

更新日期：2010-05-01 00:00:00

abstract：:Hematodermic neoplasm (HN) is a clinically aggressive neoplasm with a high incidence of cutaneous involvement and a risk of leukemic dissemination. In the recent WHO-EORTC classification, the term blastic natural killer cell lymphoma has been replaced with CD4+/CD56+ HN because of its derivation from a plasmacytoid de...

journal_title：Annals of dermatology

authors： Choi KW,Lee KY,Lee YK,Ku BS,Kim HS,Kim YH,Kim KH

更新日期：2010-05-01 00:00:00

abstract：:Pityriasis versicolor is a superficial infection of the stratum corneum, which is caused by the Malassezia species. Tge Malassezia species consist of 12 subspecies, including M. furfur, M. pachydermatis, M. symphodialis and M. globasa. The Malassezia species are classified as a normal flora, particularly in the sebum ...

journal_title：Annals of dermatology

authors： Ryu HW,Cho JW,Lee KS

更新日期：2012-08-01 00:00:00

abstract：:An atypical clinical form of pityriasis versicolor has been infrequently reported, in which cutaneous atrophy is associated with individual pityriasis versicolor lesions. The pathogenesis of this atrophy remains unclear, but is believed to be a delayed-type hypersensitivity reaction to antigens derived from the Malass...

journal_title：Annals of dermatology

authors： Yang YS,Shin MK,Haw CR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PAS...

journal_title：Annals of dermatology

authors： Youn SW,Choi CW,Kim BR,Chae JB

更新日期：2015-10-01 00:00:00