Abstract:
:Individuals differ in their level of general anxiety as well as in their level of anxiety towards specific activities, such as mathematics and spatial tasks. Both specific anxieties correlate moderately with general anxiety, but the aetiology of their association remains unexplored. Moreover, the factor structure of spatial anxiety is to date unknown. The present study investigated the factor structure of spatial anxiety, its aetiology, and the origins of its association with general and mathematics anxiety in a sample of 1,464 19-21-year-old twin pairs from the UK representative Twins Early Development Study. Participants reported their general, mathematics and spatial anxiety as part of an online battery of tests. We found that spatial anxiety is a multifactorial construct, including two components: navigation anxiety and rotation/visualization anxiety. All anxiety measures were moderately heritable (30% to 41%), and non-shared environmental factors explained the remaining variance. Multivariate genetic analysis showed that, although some genetic and environmental factors contributed to all anxiety measures, a substantial portion of genetic and non-shared environmental influences were specific to each anxiety construct. This suggests that anxiety is a multifactorial construct phenotypically and aetiologically, highlighting the importance of studying anxiety within specific contexts.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Malanchini M,Rimfeld K,Shakeshaft NG,Rodic M,Schofield K,Selzam S,Dale PS,Petrill SA,Kovas Ydoi
10.1038/srep42218subject
Has Abstractpub_date
2017-02-21 00:00:00pages
42218issn
2045-2322pii
srep42218journal_volume
7pub_type
杂志文章abstract::The high failure strain of thermoplastic elastomers (TPEs) is a very desirable feature for rechargeable Li-ion batteries by improving the lifetime of high specific capacity anode materials that undergo mechanical fractures induced by large volume variations. In this work, poly(styrene-b-2-hydroxyethyl acrylate) called...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40835-9
更新日期:2019-03-13 00:00:00
abstract::Confident characterization of the microheterogeneity of protein glycosylation through identification of intact glycopeptides remains one of the toughest analytical challenges for glycoproteomics. Recently proposed mass spectrometry (MS)-based methods still have some defects such as lack of the false discovery rate (FD...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25102
更新日期:2016-05-03 00:00:00
abstract::To unravel the molecular mechanism of defense against blister blight (BB) disease caused by an obligate biotrophic fungus, Exobasidium vexans, transcriptome of BB interaction with resistance and susceptible tea genotypes was analysed through RNA-seq using Illumina GAIIx at four different stages during ~20-day disease ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30412
更新日期:2016-07-28 00:00:00
abstract::Autoantibodies against ion channels are the cause of numerous neurologic autoimmune disorders. Frequently, such pathogenic autoantibodies have a restricted epitope-specificity. In such cases, competing antibody formats devoid of pathogenic effector functions (blocker antibodies) have the potential to treat disease by ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01019-5
更新日期:2017-04-20 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is a rising cause of hepatocellular carcinoma (HCC). We examined whether inherited pathogenic variants in candidate genes (n = 181) were enriched in patients with NAFLD-HCC. To this end, we resequenced peripheral blood DNA of 142 NAFLD-HCC, 59 NAFLD with advanced fibrosis, and ...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/s41598-019-39998-2
更新日期:2019-03-06 00:00:00
abstract::Cyanobacteria are photosynthetic prokaryotes that make major contributions to the production of the oxygen in the Earth atmosphere. The photosynthetic machinery in cyanobacterial cells is housed in flattened membrane structures called thylakoids. The structural organization of cyanobacterial cells and the arrangement ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19627
更新日期:2016-01-21 00:00:00
abstract::We describe a spin wave modulator - spintronic device aimed to control spin wave propagation by an electric field. The modulator consists of a ferromagnetic film serving as a spin wave bus combined with a synthetic multiferroic comprising piezoelectric and magnetostrictive materials. Its operation is based on the stre...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28878-w
更新日期:2018-07-18 00:00:00
abstract::Once activated, the intracellular receptor NLRP3 assembles an inflammasome protein complex that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein complex containing Hsp90. In response to stress stimuli, Hsp90 is released, and NLRP3 can be activated to promote infl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25123-2
更新日期:2018-04-30 00:00:00
abstract::ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples from TCGA and a separ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15634-9
更新日期:2017-11-09 00:00:00
abstract::Gyroviruses (GyVs) are small, single-stranded, circular DNA viruses in the genus Gyrovirus, which consists of the chicken anemia virus (CAV) prototype and nine other viral species. These different GyV species have been reported in chickens, humans, mice, and companion animals. To date, CAV has been identified in the f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49955-8
更新日期:2019-09-16 00:00:00
abstract::Gene loss is a major contributor to the evolution of bacterial gene content. Gene loss may occur as a result of shifts in environment leading to changes in the intensity and/or directionality of selection applied for the maintenance of specific genes. Gene loss may also occur in a more neutral manner, when gene functi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35168
更新日期:2016-10-13 00:00:00
abstract::The objective of this study was to examine the relationship between sleep duration and ischemic and hemorrhagic stroke in a community-based cohort. The current analysis included 95,023 Chinese participants who were free of stroke at the baseline survey (2006-2007). Cox proportional hazards models were used to calculat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33664
更新日期:2016-09-16 00:00:00
abstract::Intense geomagnetic storms can cause severe damage to electrical systems and communications. This work proposes a counting process with Weibull inter-occurrence times in order to estimate the probability of extreme geomagnetic events. It is found that the scale parameter of the inter-occurrence time distribution grows...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38918-8
更新日期:2019-02-20 00:00:00
abstract::Potential of microalgal cultivation as an alternative approach to the treatment of anaerobic digestion (AD) effluents was examined using two representative Chlorella species, Chlorella vulgaris (CV) and Chlorella protothecoides (CP). Both species effectively removed NH4+-N from the AD effluents from four digesters tre...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42521-2
更新日期:2019-04-16 00:00:00
abstract::Detection of sedimentary cycles is difficult in fine-grained or homogenous sediments but is a prerequisite for the interpretation of depositional environments. Here we use a new autocorrelation analysis to detect cycles in a homogenous sediment core, E602, from the northern shelf of the South China Sea. Autocorrelatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01653
更新日期:2013-01-01 00:00:00
abstract::In this study, the improved Aesop's fable paradigm-a series of experiments originally used to test whether some animals understand the causality associated with water replacement-was used to explore the cognitive ability of Azure-winged magpies (Cyanopica cyanus). Experimental results on causal cue tasks showed that t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80452-5
更新日期:2021-01-12 00:00:00
abstract::Spin Hall effect (SHE) has been discussed in the context of Kubo formulation, geometric physics, spin orbit force, and numerous semi-classical treatments. It can be confusing if the different pictures have partial or overlapping claims of contribution to the SHE. In this article, we present a gauge-theoretic, time-mom...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18409
更新日期:2015-12-22 00:00:00
abstract::Plant genomes encode several classes of small regulatory RNAs (sRNAs) that play critical roles in both development and stress responses. Panax notoginseng (Burk.) F.H. Chen (P. notoginseng) is an important traditional Chinese herbal medicinal plant species for its haemostatic effects. Therefore, the root yield of P. n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09670-8
更新日期:2017-08-25 00:00:00
abstract::The objective of this study was to investigate associations between education in early life and cognitive impairment in later life in Colombia. Participants were community-dwelling adults aged 60 years or older from the National Study of Health, Wellbeing and Ageing. Trained interviewers administered a shorter version...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74822-2
更新日期:2020-10-19 00:00:00
abstract::Angiosperm mitochondrial genomes (mtDNA) exhibit variable quantities of alien sequences. Many of these sequences are acquired by intracellular gene transfer (IGT) from the plastid. In addition, frequent events of horizontal gene transfer (HGT) between mitochondria of different species also contribute to their expanded...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43402
更新日期:2017-03-06 00:00:00
abstract::Aging is a multifactorial process that results in progressive loss of regenerative capacity and tissue function while simultaneously favoring the development of a large array of age-related diseases. Evidence suggests that the accumulation of senescent cells in tissue promotes both normal and pathological aging. Oxic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76925-2
更新日期:2020-11-17 00:00:00
abstract::Neuroinflammation and accompanying microglial dysfunction are now appreciated to be involved in Alzheimer's disease (AD) pathogenesis. Critical to the process of neuroinflammation are the type-I interferon (IFN) family of cytokines. Efforts to phenotypically characterize microglia within AD identify distinct populatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59917-0
更新日期:2020-02-21 00:00:00
abstract::In this study, dye-sensitized solar cells (DSSCs) has been assembled with poly(1-vinylpyrrolidone-co-vinyl acetate) (P(VP-co-VAc)) gel polymer electrolytes (GPEs) which have been incorporated with binary salt and an ionic liquid. The potential of this combination was studied and reported. The binary salt system GPEs w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27630
更新日期:2016-06-08 00:00:00
abstract::This paper reports a facile and green method for conversion of graphene oxide (GO) into graphene by low-temperature heating (80 °C) in the presence of a glass wafer. Compared to conventional GO chemical reduction methods, the presented approach is easy-scalable, operationally simple, and based on the use of a non-toxi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32488-x
更新日期:2018-09-20 00:00:00
abstract::An intermediate band in the band gap of semiconductors is fundamental to the development of the intermediate band solar cells, but it is usually produced artificially, which imposes technical challenges on the experimental realization. Here we found that there are natural intermediate bands in the band gaps of the I2-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19935-5
更新日期:2018-01-25 00:00:00
abstract::Somatostatin (SST)-positive interneurons in the anterior cingulate cortex (ACC) play important roles in neuronal diseases, memory and cognitive functions. However, their development in the ACC remains unclear. Using postnatal day 3 (P3) to P45 GIN mice, we found that most of the intrinsic membrane properties of SST in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28137
更新日期:2016-06-20 00:00:00
abstract::Shear localisation in thin bands is an important process involved in the plastic deformation of materials subject to stress. This process is often sensitive to the sample microstructure (amorphous/crystalline). Here we show using the scanning µ-SAXS technique, how these different microstructures influence the plastic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31405-6
更新日期:2018-08-28 00:00:00
abstract::How the human auditory system learns to map complex pinna-induced spectral-shape cues onto veridical estimates of sound-source elevation in the median plane is still unclear. Earlier studies demonstrated considerable sound-localisation plasticity after applying pinna moulds, and to altered vision. Several factors may ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36422-z
更新日期:2018-12-18 00:00:00
abstract::The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been implicated in regulation (tcdR and tcdC) and secretion (tcdE). To date, the PaLoc has always been found ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15023
更新日期:2015-10-08 00:00:00
abstract::Real-time in-situ temperature detection is essential in many applications. In this paper, a simple and robust optode, which uses Ruthenium (II) complex as a temperature indicator, has been developed for rapid and sensitive temperature detection in small volume samples (<5 μL). Transmission of excitation light and coll...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05009
更新日期:2014-05-30 00:00:00