Fentanyl Suppresses the Survival of CD4+ T Cells Isolated from Human Umbilical Cord Blood through Inhibition of IKKs-mediated NF-κB Activation.

abstract：:Ebola viruses (EBOVs) have been identified as an emerging threat in recent year as it causes severe haemorrhagic fever in human. Epitope-based vaccine design for EBOVs remains a top priority because a mere progress has been made in this regard. Another reason is the lack of antiviral drug and licensed vaccine although...

journal_title：Scandinavian journal of immunology

authors： Khan MA,Hossain MU,Rakib-Uz-Zaman SM,Morshed MN

更新日期：2015-07-01 00:00:00

abstract：:Hypoxia is a prominent microenvironment feature in a range of disorders including cancer, rheumatoid arthritis (RA), atherosclerosis, inflammatory bowel disease (IBD), infection and obesity. Hypoxia promotes biological functions of fibroblast-like synoviocytes via regulating hypoxia-inducible factor 1α (HIF1α). Dysreg...

journal_title：Scandinavian journal of immunology

authors： Yu R,Li C,Sun L,Jian L,Ma Z,Zhao J,Liu X

更新日期：2018-04-01 00:00:00

abstract：:Immunoprecipitation of radioiodinated hairy cell leukaemia (HCL) cell lysates with monoclonal antibody (MoAb) HML-1, originally reported to recognize intraepithelial T cells, and with MoAb B-ly7, originally reported to react with HCL, led to identical biochemical characteristics. In SDS-PAGE under reducing conditions,...

journal_title：Scandinavian journal of immunology

authors： Moldenhauer G,Mielke B,Dörken B,Schwartz-Albiez R,Möller P

更新日期：1990-08-01 00:00:00

abstract：:Murine hepatocytes cultured in the presence of human recombinant interleukin-6 (IL-6) show increased synthesis of fibrinogen and complement component C3 by the addition of histamine. No similar effect was achieved when murine hepatocytes were treated with histamine alone or with histamine and interleukin-1 alpha toget...

journal_title：Scandinavian journal of immunology

authors： Rokita H,Falus A,Biró J,Smolen J,Kordula T,Stalinska K

更新日期：1992-06-01 00:00:00

abstract：:The production of type 1 (interferon or IFN-gamma) and type 2 (interleukin or IL-4 and IL-10) cytokines by mitogen-stimulated peripheral blood mononuclear cells (PBMCs) obtained from asymptomatic human immunodeficiency virus-seropositive (HIV+) patients untreated with any antiviral, antibacterial or antimycotic drugs,...

journal_title：Scandinavian journal of immunology

authors： Canaris AD,Caruso A,Licenziati S,Cantalamessa A,De Francesco MA,Fallacara F,Fiorentini S,Dima F,Martinelli F,Manca N,Balsari A,Turano A

更新日期：1998-02-01 00:00:00

abstract：:To determine whether the genetic background of the insulin-producing beta cells of the pancreas contributes to autoimmune diabetes susceptibility, we have used a model of the disease based on transferring spleen cells from nonobese diabetic (NOD) <--> C57BL/6 (B6) embryo aggregation (EA) chimeras into B6 and NOD irrad...

journal_title：Scandinavian journal of immunology

authors： Colucci F,Bergman ML,Lejon K,Holmberg D

更新日期：1998-12-01 00:00:00

abstract：:This study was designed to determine seasonal changes in cytokines, soluble CD23 and specific IgE in the serum of patients with seasonal allergic rhinitis, and the effect of immunotherapy on these seasonal changes. Fifty-four patients with seasonal allergic rhinitis caused by Japanese ceder pollens were divided into a...

journal_title：Scandinavian journal of immunology

authors： Ohashi Y,Nakai Y,Kakinoki Y,Ohno Y,Tanaka A,Masamoto T,Sakamoto H,Washio Y,Kato A

更新日期：1997-07-01 00:00:00

abstract：:There is convincing evidence that certain combinations of alleles within the human leucocyte antigen (HLA) complex, particularly within HLA-DQ, are associated with either resistance or susceptibility to insulin-dependent diabetes mellitus (IDDM). A previous study conducted on a large, well-defined group of patients de...

journal_title：Scandinavian journal of immunology

authors： Baisch JM,Capra JD

更新日期：1992-08-01 00:00:00

abstract：:An immunization protocol that induces antibodies (Abs) directed to cryptic epitopes of a protein antigen (Ag) reduces the efficacy of vaccines that ideally should induce Abs against native epitopes. We have shown earlier that viral infections concomitant with immunization against a protein tend to shift the Ab specifi...

journal_title：Scandinavian journal of immunology

authors： Gómez KA,Longhi SA,Marino VJ,Mathieu PA,Loureiro ME,Coutelier JP,Roguin LP,Retegui LA

更新日期：2003-02-01 00:00:00

abstract：:Human endothelial cells (EC), cultured serum-free, synthesize de novo protein which increasingly bind to agarose beads (an alternative pathway activator), until a plateau phase is reached after 24-48 h. EC synthesize functional C3, C5, C6, C8 and C9, which were detected on co-cultured agarose beads, using relevant pol...

journal_title：Scandinavian journal of immunology

authors： Johnson E,Hetland G

更新日期：1991-06-01 00:00:00

abstract：:Physiological ageing is accompanied by decline in immune system function and immune alteration during ageing increases susceptibility to infections. We retrospectively analysed the data for complete blood count (CBC) and lymphocyte subsets from infant to elderly age groups to determine changes during ageing. Data from...

journal_title：Scandinavian journal of immunology

authors： Valiathan R,Ashman M,Asthana D

更新日期：2016-04-01 00:00:00

abstract：:The stem cells for the definitive haematopoiesis are derived from intra-embryonic sources originally described in an avian model and later also in mammals. However, the molecular make-up of the early embryonic haematopoietic progenitors is not yet clearly defined. We have recently characterized the phenotype of prethy...

journal_title：Scandinavian journal of immunology

authors： Lampisuo M,Katevuo K,Lassila O

更新日期：1998-07-01 00:00:00

abstract：:Antibodies to crude leukocyte interferon (CIF) were bound to Sepharose 4B, and CIF was chromatographed. A relationship between recovered interferon and percentage binding of the antibodies to Sepharose 4B was observed. Highest recovery was obtained when only 50%-85% of th- antibodies were bound. When CIF was subjected...

journal_title：Scandinavian journal of immunology

authors： Berg K

更新日期：1977-01-01 00:00:00

abstract：:Using ELISA, we have quantified the levels of IL-2 and IFN-gamma in the oral mucosa, ear skin and regional and distant lymph nodes in an experimental murine model of contact sensitivity (CS), induced by the hapten oxazolone (OXA). Compared to normal conditions, the levels of IL-2 peaked early (4-6 h) after hapten expo...

journal_title：Scandinavian journal of immunology

authors： Ahlfors EE,Lyberg T

更新日期：2010-07-01 00:00:00

abstract：:Depletion of adherent cells from stimulator and responder lymphocytes by a single filtration through nylon wool columns led to complete abrogation of the cytotoxic response to the stimulating alloantigen. Cytotoxic responses were restored by adding anti-Thy-1 + complement-greated normal peritoneal exudate cells (PEC) ...

journal_title：Scandinavian journal of immunology

authors： Symington FW,Teh HS

更新日期：1980-01-01 00:00:00

abstract：:In the present study evidence is presented that SAA in serum complexes to a carrier protein with a molecular weight of 100,000-200,000 daltons, with mobility in the alpha-region on electrophoresis, and with a rather low normal serum concentration. The carrier protein is apparently not albumin. SAA isolated from the ca...

journal_title：Scandinavian journal of immunology

authors： Skogen B,Natvig JB,Michaelsen TE,Anders RF

更新日期：1977-01-01 00:00:00

abstract：:Neuraminidase-treated lymphocytes from the peripheral blood of normal human donors were fractionated on columns charged with Helix pomatia haemagglutinin (HP) coupled to Sepharose 4B. While lymphocytes lacking HP receptors (HP-) passed directly through the column (fraction I), lymphocytes with HP receptors (HP+) were ...

journal_title：Scandinavian journal of immunology

authors： Pape GR,Troye M,Perlmann P

更新日期：1979-01-01 00:00:00

abstract：:The role of Lyt 1+ T-cell-derived secondard CTL inducing factor allowed the cloning of alloreactive cytotoxic T lymphocytes (CTL) by the limiting dilution approach. Several monoclonal cell lines were established in vitro. The lytic activity of some of the cell lines exceeded that of CTL from bulk cultures; that is, 50...

journal_title：Scandinavian journal of immunology

authors： Schawaller R,Röllinghoff M,Wagner H

更新日期：1980-01-01 00:00:00

abstract：:The main object of this study was to see whether or not chromatin constituents are present in cell membranes. The binding of antinuclear antibodies (ANA) to plasma membranes of leucocytes was studied by using autoantibodies and induced antibodies to different histones and histone peptides, and autoantibodies to double...

journal_title：Scandinavian journal of immunology

authors： Rekvig OP

更新日期：1989-01-01 00:00:00

abstract：:Modified C-reactive protein (mCRP) has been reported to non-specifically bind to immunoglobulins; notwithstanding, the nature of these interactions is not clear. The aim of this study was to investigate the binding of antibodies directed against HSA and IgG to mCRP, fibrinogen (Fg), IgG, fibronectin (Fn) and C1q and i...

journal_title：Scandinavian journal of immunology

authors： Boncler M,Dudzińska D,Nowak J,Watała C

更新日期：2012-07-01 00:00:00

abstract：:The immunological effector mechanism responsible for the elimination of virus in murine acute non-fatal extracranial lymphocytic choriomeningitis virus infection was studied. In this infection virus clearance is generally regarded as the result of a direct action of virus-specific cytotoxic T cells (Tc cells) on virus...

journal_title：Scandinavian journal of immunology

authors： Thomsen AR,Volkert M,Bro-Jørgensen K

更新日期：1983-06-01 00:00:00

abstract：:Systemic autoimmune diseases are characterized by the development of antinuclear autoantibodies. In order to understand the immunologic events leading to the development of such antibodies, knowledge of mechanisms of immune tolerance to nuclear antigens is required. By utilizing adoptive T-cell transfer strategies wit...

journal_title：Scandinavian journal of immunology

authors： Nakken B,Davis KE,Pan ZJ,Bachmann M,Farris AD

更新日期：2003-11-01 00:00:00

abstract：:Vitamin A is a potential mediator of T helper cells in atherosclerosis. The purpose of this study was to evaluate the effect of vitamin A supplementation on expression of Th17 cells-related IL-17 and RORc genes in atherosclerotic patients. Thirty one atherosclerotic patients and 15 healthy controls were studied for 4 ...

journal_title：Scandinavian journal of immunology

authors： Mottaghi A,Ebrahimof S,Angoorani P,Saboor-Yaraghi AA

更新日期：2014-08-01 00:00:00

abstract：:Sendai virus envelope-mediated fusion was used to transfer plasma membrane vesicles of ESb lymphoma cells (H-2d) to syngeneic or allogeneic recipient cells. After fusion, ESb-specific cell surface determinants were detectable on the recipient cells, as revealed by indirect immunofluorescence and cytofluorographic anal...

journal_title：Scandinavian journal of immunology

authors： Altevogt P

更新日期：1984-09-01 00:00:00

abstract：:Subclasses of lymphocytes can be separated on gradients of non-toxic polyvinylpyrrolidone-coated colloidal silica (Percoll) by virtue of differential densities. Such gradients can yield functionally active lymphocyte populations after brief centrifugation. Gradients can be generated in a discontinuous step fashion and...

journal_title：Scandinavian journal of immunology

authors： Kurnick JT,Ostberg L,Stegagno M,Kimura AK,Orn A,Sjöberg O

更新日期：1979-01-01 00:00:00

abstract：:Coeliac disease (CD) is a very common food-sensitive enteropathy, which is triggered by gluten ingestion and is mediated by CD4(+) T cells. In addition, alterations in the intestinal microbiota that is normally involved in the homeostasis of GALT (gut-associated lymphoid tissue) seem to play a role in CD. In accordanc...

journal_title：Scandinavian journal of immunology

authors： D'Arienzo R,Stefanile R,Maurano F,Mazzarella G,Ricca E,Troncone R,Auricchio S,Rossi M

更新日期：2011-10-01 00:00:00

abstract：:We describe the effects of treatment with topical steroids or dithranol on T and dendritic cells in the skin of patients with chronic plaque psoriasis. Resolution of lesions by both types of topical treatments was accompanied by a marked decrease in epidermal T cells. In steroid treated lesions there was also a reduct...

journal_title：Scandinavian journal of immunology

authors： Baker BS,Swain AF,Griffiths CE,Leonard JN,Fry L,Valdimarsson H

更新日期：1985-11-01 00:00:00

abstract：:Deficiency of complement components within the classical pathway is associated with increased risk for immune complex disease. However, C2-deficient individuals often have a mild disease and about 50% are healthy. To study the importance of the different components for immune complex clearance, bovine serum albumin (B...

journal_title：Scandinavian journal of immunology

authors： Klint C,Gullstrand B,Sturfelt G,Truedsson L

更新日期：2000-07-01 00:00:00

abstract：:An antigen-specific T-cell line which transforms into T-lymphoma cells in vitro but apparently not in vivo is described. Membrane markers, tumorigenicity and T-cell receptor (TcR) V alpha and V beta-gene usage of the in vitro transformed T-cell line were analysed to investigate whether the transformation event was pol...

journal_title：Scandinavian journal of immunology

authors： Wegener AM,Holm B,Geisler C,Rubin B

更新日期：1990-05-01 00:00:00

abstract：:We have investigated the production of interleukin 2 (IL-2) by human T cells after their stimulation by phytohaemagglutinin (PHA). T cells isolated by rosetting with sheep erythrocytes produced high levels of IL-2. Further separation of rosette-forming cells, according to the expression of Fc receptors for IgG, showed...

journal_title：Scandinavian journal of immunology

authors： Silva AG,Alvarez JM,Bonnard GD,de Landazuri MO

更新日期：1981-09-01 00:00:00