Application of fluorescence polarization immunoassay for determination of carbamazepine in wastewater.

Abstract:

:Carbamazepine is an antiepileptic drug that can be used as a marker for the cleaning efficiency of wastewater treatment plants. Here, we present the optimization of a fast and easy on-site measurement system based on fluorescence polarization immunoassay and the successful application to wastewater. A new monoclonal highly specific anti-carbamazepine antibody was applied. The automated assay procedure takes 16 min and does not require sample preparation besides filtration. The recovery rates for carbamazepine in wastewater samples were between 60.8 and 104% with good intra- and inter-assay coefficients of variations (less than 15 and 10%, respectively). This automated assay enables for the on-site measurement of carbamazepine in wastewater treatment plants.

journal_name

J Environ Manage

authors

Oberleitner L,Dahmen-Levison U,Garbe LA,Schneider RJ

doi

10.1016/j.jenvman.2017.01.063

subject

Has Abstract

pub_date

2017-05-15 00:00:00

pages

92-97

eissn

0301-4797

issn

1095-8630

pii

S0301-4797(17)30081-6

journal_volume

193

pub_type

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