Hot Topic: Global Burden of Treating Hypertension-What is the Role of the Emergency Department?

Abstract:

:Hypertension (HTN) is the most common modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality worldwide. Lower- and middle-income countries (LMICs) are projected to bear the vast majority of this disease burden, but local and regional health care delivery systems in these countries are ill equipped to meet this need. Emergency care is receiving increased recognition as a crucial component of public and community health. The rapid evolution of emergency care in LMICs provides a unique opportunity to develop innovative strategies, incorporating existing strengths of emergency departments, to address this paradigm shift in the disease burden associated with HTN on a global scale.

journal_name

Curr Hypertens Rep

authors

Brody AM,Kumar VA,Levy PD

doi

10.1007/s11906-017-0707-4

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

8

issue

1

eissn

1522-6417

issn

1534-3111

pii

10.1007/s11906-017-0707-4

journal_volume

19

pub_type

杂志文章,评审
  • Isolated Systolic Hypertension in Young and Middle-Aged Adults.

    abstract::Young and middle-aged adults (ages ≤50 years) are increasingly prone to stroke, kidney disease, and worsening cardiovascular disease (CVD) mortality. An alarming increase in the prevalence of high blood pressure (BP) may underlie the adverse trend. However, there is often uncertainty in BP management for young and mid...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-016-0686-x

    authors: Yano Y,Lloyd-Jones DM

    更新日期:2016-11-01 00:00:00

  • Combination therapy as first-line treatment for hypertension.

    abstract::With the cut-off point between "normal" and "high" blood pressure (BP) being pushed increasingly downward, especially for patients with multiple cardiovascular risk factors, most hypertensives need more than one antihypertensive agent to reach their target BP. In this article, we examine the rationale for combining dr...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-004-0020-x

    authors: Gavras I,Rosenthal T

    更新日期:2004-08-01 00:00:00

  • The epithelial sodium channel in hypertension.

    abstract::Our understanding of Na(+) transport defects has exploded in the past several years, and has provided unique insights into epithelial transport processes, and unusual clinical syndromes resulting from mutations of specific ion transporters. These genetic disorders affect Na(+) balance, with both Na(+) retaining and Na...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-999-0013-x

    authors: Warnock DG

    更新日期:1999-04-01 00:00:00

  • Comparison Between Automated Office Blood Pressure Measurements and Manual Office Blood Pressure Measurements-Implications in Individual Patients: a Systematic Review and Meta-analysis.

    abstract:PURPOSE OF REVIEW:Automated office blood pressure (AOBP) measurements may provide more accurate estimation of blood pressure (BP) than manual office blood pressure (MOBP) measurements. This systematic review investigated the diagnostic performance of AOBP and MOBP using ambulatory blood pressure measurement (ABPM) as r...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-020-01118-1

    authors: Bo Y,Kwok KO,Chu KK,Leung EY,Yu CP,Wong SY,Lee EK

    更新日期:2021-01-15 00:00:00

  • Cognitive function in hypertensive children.

    abstract::Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-014-0508-y

    authors: Lande MB,Kupferman JC

    更新日期:2015-01-01 00:00:00

  • Using health information technology to improve hypertension management.

    abstract::High-quality medical care requires implementing evidence-based best practices, with continued monitoring to improve performance. Implementation science is beginning to identify approaches to developing, implementing, and evaluating quality improvement strategies across health care systems that lead to good outcomes fo...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-008-0038-6

    authors: Goldstein MK

    更新日期:2008-06-01 00:00:00

  • Issues of clinical trial design and data interpretations in hypertension.

    abstract::There are many drug studies for the treatment of hypertension. Most studies compare one drug with another to determine if a drug or class of drugs have unique benefits. In evaluating drug trials, separation of hypertension as compared with atherosclerotic events is important. Trials that focus on prevention of hyperte...

    journal_title:Current hypertension reports

    pub_type: 杂志文章

    doi:10.1007/s11906-999-0046-1

    authors: Kuller LH

    更新日期:1999-08-01 00:00:00

  • Factors Responsible for Obesity-Related Hypertension.

    abstract:PURPOSE OF REVIEW:The major health issue of being overweight or obese relates to the development of hypertension, insulin resistance and diabetic complications. One of the major underlying factors influencing the elevated blood pressure in obesity is increased activity of the sympathetic nerves to particular organs suc...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-017-0750-1

    authors: Lim K,Jackson KL,Sata Y,Head GA

    更新日期:2017-07-01 00:00:00

  • Chlorthalidone: mechanisms of action and effect on cardiovascular events.

    abstract::How chlorthalidone (CTDN) reduces risk for cardiovascular events (CVEs) can be considered in light of its ability to lower blood pressure (BP) and its non-BP related, pleiotropic effects. The mechanism by which CTDN lowers BP is unclear but may include alterations in whole body regulation and vasodilatory actions on v...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-013-0372-1

    authors: Roush GC,Buddharaju V,Ernst ME,Holford TR

    更新日期:2013-10-01 00:00:00

  • Is population-wide diuretic use directly associated with the incidence of end-stage renal disease in the United States?

    abstract::In the quest for "evidence-based" medicine, an accepted hierarchy of evidence has been proposed. This hierarchy places in vitro studies and animal data at the base, and puts systematic reviews, meta-analyses, and randomized controlled trials at the pinnacle. However, when clinical medicine faces questions that have no...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-006-0054-3

    authors: Hawkins RG

    更新日期:2006-06-01 00:00:00

  • Pathophysiology of obesity hypertension.

    abstract::Excess weight gain is a major cause of essential hypertension, and abnormal kidney function appears to be a cause as well as a consequence of obesity hypertension. Excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role in mediating increased blood pressure associated with w...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-000-0073-4

    authors: Hall JE

    更新日期:2000-04-01 00:00:00

  • Spironolactone in congestive heart failure.

    abstract::When a large multicenter research trial is abruptly terminated, it is usually a consequence of significant adverse events. In contrast, when the Randomized Aldactone Evaluation Study (RALES) mortality trial was discontinued 18 months early, it was because of the prominent salutary effect of spironolactone, added to st...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-000-0027-x

    authors: Soberman JE,Weber KT

    更新日期:2000-10-01 00:00:00

  • Statins and blood pressure regulation.

    abstract::Hypertension and high serum cholesterol levels are two of the most relevant risk factors for cardiovascular diseases. A combined increase in both risk factors has been reported in a significant proportion of patients with coronary artery disease. Statins are the most widely used drugs to treat hypercholesterolemia, an...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-001-0090-y

    authors: Borghi C,Veronesi M,Prandin MG,Dormi A,Ambrosioni E

    更新日期:2001-08-01 00:00:00

  • Endothelial arginase: a new target in atherosclerosis.

    abstract::Decreased endothelial nitric oxide (NO) bioavailability as it relates to endothelial dysfunction plays an important role in various cardiovascular disorders, including athero-sclerosis. Recent research has provided evidence that endothelial dysfunction in atherosclerosis is not primarily caused by decreased endothelia...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-006-0041-8

    authors: Yang Z,Ming XF

    更新日期:2006-04-01 00:00:00

  • Relationship Between Antihypertensive Medications and Cognitive Impairment: Part I. Review of Human Studies and Clinical Trials.

    abstract:PURPOSE OF REVIEW:There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer's disease; however, associations between antihypertensive medications (AHMs) and dementia risk are less consistent. An increased interest in AHM has resulted in ex...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-016-0674-1

    authors: Yasar S,Schuchman M,Peters J,Anstey KJ,Carlson MC,Peters R

    更新日期:2016-08-01 00:00:00

  • Effects of antihypertensive treatment on endothelial function.

    abstract::Essential hypertension is characterized by endothelial dysfunction due to reduced availability of nitric oxide (NO) secondary to increased generation of oxygen-free radicals. Some antihypertensive drugs may improve or restore endothelial function independently of their blood pressure lowering effect. The newer generat...

    journal_title:Current hypertension reports

    pub_type: 杂志文章

    doi:10.1007/s11906-011-0207-x

    authors: Virdis A,Ghiadoni L,Taddei S

    更新日期:2011-08-01 00:00:00

  • Hypertension in diabetes: the role of the vasculature.

    abstract::This review is focused on the interplay between two major factors affecting the vascular tree in diabetes, insulin resistance, and hyperglycemia. The implications for vascular function, structure, and the interaction between vascular cells and other tissues by which they are affected under these conditions are reviewe...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-004-0082-9

    authors: Stern N,Marcus Y

    更新日期:2004-04-01 00:00:00

  • Nycthemeral relationship between renal function and sodium homeostasis.

    abstract::Nycthemeral changes in renal function have been known for a long time, but our knowledge about the underlying mechanisms is still far from complete. From a theoretical point of view, many physiological systems could be involved in turning the kidney from a sodium-excretory organ during daytime into a sodium-conserving...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-011-0183-1

    authors: de Leeuw PW

    更新日期:2011-04-01 00:00:00

  • Impact of the 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines on the Next Blood Pressure Guidelines in Asia.

    abstract:PURPOSE OF REVIEW:To estimate the impact of the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines for high blood pressure (BP) on the next hypertension guidelines in Asia. RECENT FINDINGS:The 2017 ACC/AHA guidelines for high BP in adults changed the diagnostic threshold and the manage...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-019-0906-2

    authors: Nakagawa N,Hasebe N

    更新日期:2019-01-10 00:00:00

  • Preeclampsia and Glomerulonephritis: A Bidirectional Association.

    abstract:PURPOSE OF REVIEW:We focus on the current understanding of preeclampsia (PE) in order to examine how it mediates glomerular injury and affects the course of glomerulonephritis (GNs). In addition, this review discusses the role of GNs on the development of PE. RECENT FINDINGS:In PE, the dysfunctional utero-placental pe...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-020-1033-9

    authors: Di Leo V,Capaccio F,Gesualdo L

    更新日期:2020-03-21 00:00:00

  • Neurogenic factors in renal hypertension.

    abstract::Hypertension is very common in patients with chronic renal failure and contributes to cardiovascular morbidity and mortality. Several mechanisms may contribute to hypertension in these patients, but recently a large body of evidence supports the notion that activation of the sympathetic nervous system (SNS) may play a...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-002-0016-3

    authors: Campese VM,Krol E

    更新日期:2002-06-01 00:00:00

  • The "J curve" problem revisited: old and new findings.

    abstract::This paper critically addresses the issue of the "J-curve" paradox--the finding described in studies performed about 30 years ago indicating that treatment-induced systolic blood pressure values below 120 or 125 mm Hg and diastolic blood pressure values below 75 mm Hg are characterized by an increase, rather than a re...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-010-0121-7

    authors: Grassi G,Quarti-Trevano F,Dell'Oro R,Mancia G

    更新日期:2010-08-01 00:00:00

  • Effectiveness of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training in Hypertensive Patients: a Systematic Review and Meta-Analysis.

    abstract:PURPOSE OF REVIEW:The purpose of this meta-analysis is to compare the effects of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) on blood pressure of hypertensive individuals. RECENT FINDINGS:Continuous aerobic training programs are successful in health promotion and are effec...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11906-020-1030-z

    authors: Leal JM,Galliano LM,Del Vecchio FB

    更新日期:2020-03-03 00:00:00

  • Epithelial sodium channel, salt intake, and hypertension.

    abstract::The epithelial sodium channel (ENaC) is a membrane protein made of three different but homologous subunits (a, b, and g) present in the apical membrane of epithelial cells of, for example, the distal nephron. This channel is responsible for salt reabsorption in the kidney and can cause human diseases by increasing cha...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-003-0005-1

    authors: Hummler E

    更新日期:2003-02-01 00:00:00

  • Effects of relaxin on arterial dilation, remodeling, and mechanical properties.

    abstract::Administering relaxin to conscious rats and humans elicits systemic and renal vasodilation. The molecular mechanisms vary according to the duration of relaxin exposure-so-called "rapid" (within minutes) or "sustained" (hours to days) vasodilatory responses-both being endothelium-dependent. Rapid responses are mediated...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-011-0231-x

    authors: Conrad KP,Shroff SG

    更新日期:2011-12-01 00:00:00

  • Effects of Probiotics on Patients with Hypertension: a Systematic Review and Meta-Analysis.

    abstract:PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11906-020-01042-4

    authors: Chi C,Li C,Wu D,Buys N,Wang W,Fan H,Sun J

    更新日期:2020-03-21 00:00:00

  • Systemic blood pressure and stroke outcome and recurrence.

    abstract::Although it is clear that hypertension is a primary cause of stroke, there has been controversy concerning blood pressure management after stroke. Recent studies indicate that lowering systemic blood pressure after stroke reduces the risk for recurrent stroke or vascular events, but other studies provide evidence that...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-005-0058-4

    authors: Hillis AE

    更新日期:2005-02-01 00:00:00

  • Dietary Fat and Blood Pressure.

    abstract:PURPOSE OF REVIEW:Do dietary fats lower blood pressure? This review covers total fats, individual fatty acids and foods that provide specific fats. RECENT FINDINGS:Evidence for blood pressure lowering is stronger for supplements providing individual marine fatty acids than for fish intake since data on fish consumptio...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-019-0918-y

    authors: Nestel PJ

    更新日期:2019-02-12 00:00:00

  • Obstructive sleep apnea and hypertension: a critical review.

    abstract::Obstructive sleep apnea (OSA) is a prevalent sleep disorder which is characterized by recurrent upper closure with oxygen desaturation and sleep disruption. OSA increases the risk of vascular disorders in the form of stroke, myocardial infarction, congestive heart failure, and hypertension. The mechanisms underlying t...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-014-0482-4

    authors: Mohsenin V

    更新日期:2014-10-01 00:00:00

  • Dysfunctional brain-bone marrow communication: a paradigm shift in the pathophysiology of hypertension.

    abstract::It is widely accepted that the pathophysiology of hypertension involves autonomic nervous system dysfunction, as well as a multitude of immune responses. However, the close interplay of these systems in the development and establishment of high blood pressure and its associated pathophysiology remains elusive and is t...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-013-0361-4

    authors: Santisteban MM,Zubcevic J,Baekey DM,Raizada MK

    更新日期:2013-08-01 00:00:00