Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging.

Abstract:

:Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration, enzymatic reactions, and to equilibrate the regenerative demands of balanced tissue homeostasis. The identification of the mechanisms by which ADSCs accomplish these functions for dermatological rejuvenation and wound healing has great potential to identify novel targets for the treatment of disorders and combat aging. Herein, we review new insights into the role of adipose-derived stem cells in the maintenance of dermal and epidermal homeostasis, and recent advances in clinical applications of ADSCs related to dermatology.

journal_name

Int J Mol Sci

authors

Gaur M,Dobke M,Lunyak VV

doi

10.3390/ijms18010208

subject

Has Abstract

pub_date

2017-01-20 00:00:00

issue

1

issn

1422-0067

pii

ijms18010208

journal_volume

18

pub_type

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