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Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese.

Abstract：

:Phytosterols found naturally in plants are known to reduce cholesterol absorption in the gut. The traditional southern Chinese diet typically contains many vegetables and not much meat, and there is high prevalence of lactose intolerance in Chinese; we therefore aimed to test if phytosterols-enriched milk is effective in lowering serum LDL-cholesterol in Chinese. Two hundred and twenty-one participants (41 men and 180 women; age 24-79) without cholesterol-lowering drugs or diabetes mellitus were randomized to daily intake of phytosterols-enriched low-fat milk which contained 1.5 g phytosterols per day (N = 110) or a conventional low-fat milk (N = 111) for three weeks. Fasting bloods were taken before and at the end of the study for the measurement of lipid and glucose profile. Physical examination was also performed. Comparing treatment with control, treatment group had significant decrease in serum LDL-cholesterol level (9.5 ± 2.0%; p < 0.0001). Phytosterols intake also decreased total cholesterol (P < 0.0001) and diastolic blood pressure (P = 0.01). Consumption of a phytosterols-enriched low-fat milk led to a significant fall in LDL-cholesterol, total cholesterol, and diastolic blood pressure in Chinese. This can be recommended as part of a healthy diet for people. (ClinicalTrials.gov identifier: NCT02541201; Date of registration: 26 Aug 2015).

journal_name

Sci Rep

journal_title

Scientific reports

authors

Cheung CL,Ho DK,Sing CW,Tsoi MF,Cheng VK,Lee GK,Ho YN,Cheung BM

doi

10.1038/srep41084

subject

Has Abstract

pub_date

2017-01-24 00:00:00

pages

41084

issn

2045-2322

pii

srep41084

journal_volume

7

pub_type

杂志文章,随机对照试验

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