Enhanced intracellular delivery and antibacterial efficacy of enrofloxacin-loaded docosanoic acid solid lipid nanoparticles against intracellular Salmonella.

abstract：:In order to screen out an effective bone loss protectant from natural plant polyphenol and to elucidate the mechanism of the plant polyphenols that alleviate bone loss under simulated microgravity, the proliferation activities of 9 total polyphenol extracts from natural product (TPENP) on osteoblasts were measured. Po...

journal_title：Scientific reports

authors： Diao Y,Chen B,Wei L,Wang Z

更新日期：2018-08-24 00:00:00

abstract：:Serial 3-dimensional dental model superimposition provides a risk-free, detailed evaluation of morphological alterations on a patient's mouth. Here, we evaluated accuracy and precision of five palatal areas, used for superimposition of maxillary 3D digital dental casts. Sixteen pre- and post-orthodontic treatment dent...

journal_title：Scientific reports

authors： Vasilakos G,Schilling R,Halazonetis D,Gkantidis N

更新日期：2017-07-19 00:00:00

abstract：:Bacterial outer membrane lipopolysaccharide (LPS) potently stimulates the mammalian innate immune system, and can lead to sepsis, the primary cause of death from infections. LPS is sensed by Toll-like receptor 4 (TLR4) in complex with its lipid-binding coreceptor MD-2, but subtle structural variations in LPS can profo...

journal_title：Scientific reports

authors： Paramo T,Tomasio SM,Irvine KL,Bryant CE,Bond PJ

更新日期：2015-12-09 00:00:00

abstract：:The correlation between hepatitis B virus (HBV) infection and metabolic syndrome (MetS) remains to be clarified. In this study, we explored this association in a large population in Southwest China. This was a cross-sectional study, with pooled adult health data. Multivariate logistic regression analysis, controlling ...

journal_title：Scientific reports

authors： Yan LB,Liao J,Han N,Zhou LY,Wang XE,Wang YJ,Tang H

更新日期：2020-04-21 00:00:00

abstract：:Malaria is a fatal disease that displays a spectrum of symptoms and severity, which are determined by complex host-parasite interactions. It has been difficult to study the effects of parasite strains on disease severity in human infections, but the mechanisms leading to specific disease phenotypes can be investigated...

journal_title：Scientific reports

authors： Lacerda-Queiroz N,Riteau N,Eastman RT,Bock KW,Orandle MS,Moore IN,Sher A,Long CA,Jankovic D,Su XZ

更新日期：2017-09-05 00:00:00

abstract：:Cu removal by a novel multi-amines decorated resin (PAMD) from wastewater in the absence or presence of citric acid (CA) was examined. Adsorption capacity of Cu onto PAMD markedly increased by 186% to 5.07 mmol/g in the presence of CA, up to 7 times of that onto four commercial resins under the same conditions. Preloa...

journal_title：Scientific reports

authors： Ling C,Liu F,Pei Z,Zhang X,Wei M,Zhang Y,Zheng L,Zhang J,Li A,Xing B

更新日期：2015-05-12 00:00:00

abstract：:Synovial fibroblasts (SF) were reported to produce B cell activating factor (BAFF) in response to stimulation with interferon-γ (IFN-γ) or tumor necrosis factor (TNF). However, the influence of these pro-inflammatory cytokines on other receptors/ligands of the TNF superfamily or associated cytokine receptors in SF has...

journal_title：Scientific reports

authors： Lowin T,Anssar TM,Bäuml M,Classen T,Schneider M,Pongratz G

更新日期：2020-01-21 00:00:00

abstract：:Earlier studies showed that endogenous estrogens have neuroprotective effect against oxidative damage. The present study seeks to investigate the protective effect of various endogenous estrogen metabolites against oxidative neurotoxicity in vitro and in vivo. Using immortalized mouse hippocampal neuronal cells as an ...

journal_title：Scientific reports

authors： Choi HJ,Lee AJ,Kang KS,Song JH,Zhu BT

更新日期：2020-04-29 00:00:00

abstract：:The interaction between cellulase enzymes and their substrates is of central importance to several technological and scientific challenges. Here we report that the binding of cellulose binding modules (CBM) from Trichoderma reesei cellulases Cel6A and Cel7A show a major difference in how they interact with substrates ...

journal_title：Scientific reports

authors： Arola S,Linder MB

更新日期：2016-10-17 00:00:00

abstract：:Current-induced spin-orbit torques (SOTs) in structurally asymmetric multilayers have been used to efficiently manipulate magnetization. In a structure with vertical symmetry breaking, a damping-like SOT can deterministically switch a perpendicular magnet, provided an in-plane magnetic field is applied. Recently, it h...

journal_title：Scientific reports

authors： Yu G,Akyol M,Upadhyaya P,Li X,He C,Fan Y,Montazeri M,Alzate JG,Lang M,Wong KL,Khalili Amiri P,Wang KL

更新日期：2016-04-06 00:00:00

abstract：:N(1)-methyladenosine (m(1)A) is a prominent RNA modification involved in many biological processes. Accurate identification of m(1)A site is invaluable for better understanding the biological functions of m(1)A. However, limitations in experimental methods preclude the progress towards the identification of m(1)A site...

journal_title：Scientific reports

authors： Chen W,Feng P,Tang H,Ding H,Lin H

更新日期：2016-08-11 00:00:00

abstract：:A novel flexible electret membrane, exhibiting persistent electrostatic effect, distinctive temperature stability and outstanding capability of resistance to harsh environment and fatigue, is demonstrated by experiment. Its excellent electret performance is correlated to the synergy of three factors, which are space c...

journal_title：Scientific reports

authors： Huiming X,Gangjin C,Xumin C,Zhi C

更新日期：2017-08-16 00:00:00

abstract：:Detailed structural analyses of the mushroom body which plays critical roles in olfactory learning and memory revealed that it is directly connected with multiple primary sensory centers in Drosophila. Connectivity patterns between the mushroom body and primary sensory centers suggest that each mushroom body lobe proc...

journal_title：Scientific reports

authors： Yagi R,Mabuchi Y,Mizunami M,Tanaka NK

更新日期：2016-07-11 00:00:00

abstract：:The possibility of cluster radioactivity (CR) of the neutron-deficient nuclei in the trans-tin region is explored by using the effective liquid drop model (ELDM), generalized liquid drop model (GLDM), and several sets of analytic formulas. It is found that the minimal half-lives are at Nd = 50 (Nd is the neutron numbe...

journal_title：Scientific reports

authors： Gao Y,Cui J,Wang Y,Gu J

更新日期：2020-06-04 00:00:00

abstract：:The strange three-dimensional flight behaviour of slowly spinning soccer balls is one of the most interesting and unknown phenomenon associated with the trajectories of sports balls. Many spectators have experienced numerous exciting and emotional instances while observing the curious flight behaviour of these balls. ...

journal_title：Scientific reports

authors： Mizota T,Kurogi K,Ohya Y,Okajima A,Naruo T,Kawamura Y

更新日期：2013-01-01 00:00:00

abstract：:The psychrophilic (cold-loving) fungus Pseudogymnoascus destructans was discovered more than a decade ago to be the pathogen responsible for white-nose syndrome, an emerging disease of North American bats causing unprecedented population declines. The same species of fungus is found in Europe but without associated mo...

journal_title：Scientific reports

authors： Ren P,Rajkumar SS,Zhang T,Sui H,Masters PS,Martinkova N,Kubátová A,Pikula J,Chaturvedi S,Chaturvedi V

更新日期：2020-08-17 00:00:00

abstract：:Biological functions of hyaluronic acid (HA) depend on its molecular size. High-molecular weight HA (HMW-HA) is an important component of the endothelial wall and has anti-inflammatory and antioxidant properties. Under inflammation or hypoxia, HMW-HA is degraded by hyaluronidases, such as HYAL-1 resulting in pro-infla...

journal_title：Scientific reports

authors： Meszaros M,Kis A,Kunos L,Tarnoki AD,Tarnoki DL,Lazar Z,Bikov A

更新日期：2020-11-10 00:00:00

abstract：:In this paper, we propose a strategy for the control of mobile chaotic oscillators by adaptively rewiring connections between nearby agents with local information. In contrast to the dominant adaptive control schemes where coupling strength is adjusted continuously according to the states of the oscillators, our metho...

journal_title：Scientific reports

authors： Zhou J,Zou Y,Guan S,Liu Z,Xiao G,Boccaletti S

更新日期：2017-11-22 00:00:00

abstract：:Fine-motor impairment (FMI) is progressively expressed in early Parkinson's Disease (PD) patients and is now known to be evident in the immediate prodromal stage of the condition. The clinical techniques for detecting FMI may not be robust enough and here, we show that the subtle FMI of early PD patients can be effect...

journal_title：Scientific reports

authors： Iakovakis D,Chaudhuri KR,Klingelhoefer L,Bostantjopoulou S,Katsarou Z,Trivedi D,Reichmann H,Hadjidimitriou S,Charisis V,Hadjileontiadis LJ

更新日期：2020-07-28 00:00:00

abstract：:Rice is the most important crop in the world, acting as the staple food for over half of the world's population. The evolutionary relationships of cultivated rice and its wild relatives have remained contentious and inconclusive. Here we report on the use of whole chloroplast sequences to elucidate the evolutionary an...

journal_title：Scientific reports

authors： Wambugu PW,Brozynska M,Furtado A,Waters DL,Henry RJ

更新日期：2015-09-10 00:00:00

abstract：:KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current study aimed to design a...

journal_title：Scientific reports

authors： Schelleckes K,Schmitz B,Lenders M,Mewes M,Brand SM,Brand E

更新日期：2018-03-09 00:00:00

abstract：:Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Although HD is monogenic, its molecular manifestation appears highly complex and involves multiple cellular processes. The recent application of high throughput platforms such as mic...

journal_title：Scientific reports

authors： Kalathur RKR,Pedro Pinto J,Sahoo B,Chaurasia G,Futschik ME

更新日期：2017-07-12 00:00:00

abstract：:Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring. Exercise improves metabolism partly by upregulating mitochondrial biogenesis or function, via increased levels of nicotinamide adenine dinucleotide (NAD+). We have shown that the NAD+ precursor, nicotinamide mononucleotide (NMN)...

journal_title：Scientific reports

authors： Uddin GM,Youngson NA,Doyle BM,Sinclair DA,Morris MJ

更新日期：2017-11-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Paulino PG,Almosny N,Oliveira R,Viscardi V,Müller A,Guimarães A,Baldani C,da Silva C,Peckle M,Massard C,Santos H

更新日期：2020-07-29 00:00:00

abstract：:Highly Tm(3+) doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm(3+) doped barium gallo-germanate (BGG) glasses....

journal_title：Scientific reports

authors： Wen X,Tang G,Yang Q,Chen X,Qian Q,Zhang Q,Yang Z

更新日期：2016-02-01 00:00:00

abstract：:Concurrent spread of Tomato yellow leaf curl virus (TYLCV) with invasion of Bemisia tabaci Q rather than B in China suggests a more mutualistic relationship between TYLCV and Q than B. To assess this hypothesis, we quantified the impacts of TYLCV on the performance and competitiveness of B and Q in the laboratory. The...

journal_title：Scientific reports

authors： Pan H,Chu D,Liu B,Shi X,Guo L,Xie W,Carrière Y,Li X,Zhang Y

更新日期：2013-01-01 00:00:00

abstract：:Bt cotton was genetically modified to produce insecticidal proteins targeting Lepidopteran pests and is therefore only minimally affected by caterpillar damage. This could lead to reduced levels of inherent, systemically inducible defensive compounds in Bt cotton which might benefit other important cotton herbivores s...

journal_title：Scientific reports

authors： Eisenring M,Naranjo SE,Bacher S,Abbott A,Meissle M,Romeis J

更新日期：2019-02-25 00:00:00

abstract：:Models of exchange-bias in thin films have been able to describe various aspects of this technologically relevant effect. Through appropriate choices of free parameters the modelled hysteresis loops adequately match experiment, and typical domain structures can be simulated. However, the use of these parameters, notab...

journal_title：Scientific reports

authors： Benassi A,Marioni MA,Passerone D,Hug HJ

更新日期：2014-03-28 00:00:00

abstract：:Neuro-Behçet's disease (NBD) is subcategorized into parenchymal-NBD (P-NBD) and non-parenchymal-NBD types. Recently, P-NBD has been further subdivided into acute P-NBD (A-P-NBD) and chronic progressive P-NBD (CP-P-NBD). Although an increasing number of studies have reported the various clinical features of A-P-NBD and...

journal_title：Scientific reports

authors： Ishido M,Horita N,Takeuchi M,Shibuya E,Yamane T,Kawagoe T,Ishido T,Minegishi K,Yoshimi R,Kirino Y,Hirohata S,Ishigatsubo Y,Takeno M,Kaneko T,Mizuki N

更新日期：2017-08-31 00:00:00

abstract：:The protein interface is key to understand protein function, providing a vital insight on how proteins interact with each other and with other molecules. Over the years, many computational methods to compare protein structures were developed, yet evaluating interface similarity remains a very difficult task. Here, we ...

journal_title：Scientific reports

authors： Budowski-Tal I,Kolodny R,Mandel-Gutfreund Y

更新日期：2018-05-29 00:00:00