Genetic diversity among eight Dendrolimus species in Eurasia (Lepidoptera: Lasiocampidae) inferred from mitochondrial COI and COII, and nuclear ITS2 markers.

abstract：:Previous genome scan linkage analyses of the disease Kofendrerd Personality Disorder (KPD) with microsatellites led to detect some regions on chromosomes 1, 3, 5, and 9 that were identical for the three populations AI, KA, and DA but with large differences in significance levels. These differences in results may be ex...

journal_title：BMC genetics

authors： Dizier MH,Génin E,Babron MC,Bourgain C

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Non-pathological cognitive ageing is a distressing condition affecting an increasing number of people in our 'ageing society'. Oxidative stress is hypothesised to have a major role in cellular ageing, including brain ageing. RESULTS:Associations between cognitive ageing and 325 single nucleotide polymorphis...

journal_title：BMC genetics

authors： Harris SE,Fox H,Wright AF,Hayward C,Starr JM,Whalley LJ,Deary IJ

更新日期：2007-07-02 00:00:00

abstract：BACKGROUND:There is increasing evidence that the ability to adapt to seawater in teleost fish is modulated by genetic factors. Most studies have involved the comparison of species or strains and little is known about the genetic architecture of the trait. To address this question, we searched for QTL affecting osmoregu...

journal_title：BMC genetics

authors： Le Bras Y,Dechamp N,Krieg F,Filangi O,Guyomard R,Boussaha M,Bovenhuis H,Pottinger TG,Prunet P,Le Roy P,Quillet E

更新日期：2011-05-14 00:00:00

abstract：BACKGROUND:Koala (Koa) is a dominant mutation in mice causing bushy muzzle and pinna, and is associated with a chromosomal inversion on the distal half of chromosome 15. To identify the gene responsible for the Koa phenotypes, we investigated phenotypes of Koa homozygous mice and determined the breakpoints of the inver...

journal_title：BMC genetics

authors： Katayama K,Miyamoto S,Furuno A,Akiyama K,Takahashi S,Suzuki H,Tsuji T,Kunieda T

更新日期：2009-09-22 00:00:00

abstract：BACKGROUND:Sugar beet is an obligate outcrossing species. Varieties consist of mixtures of plants from various parental combinations. As the number of informative morphological characteristics is limited, this leads to some problems in variety registration research. RESULTS:We have developed 25 new microsatellite mark...

journal_title：BMC genetics

authors： Smulders MJ,Esselink GD,Everaert I,De Riek J,Vosman B

更新日期：2010-05-18 00:00:00

abstract：:We performed a bivariate analysis on cholesterol and triglyceride levels on data from the Framingham Heart Study using a new score statistic developed for the detection of potential pleiotropic, or cluster, genes. Univariate score statistics were also computed for each trait. At a significance level 0.001, linkage sig...

journal_title：BMC genetics

authors： Zhang X,Wang K,Framingham Heart Study.

更新日期：2003-12-31 00:00:00

abstract：BACKGROUND:Cattle are bred for, amongst other factors, specific traits, including parasite resistance and adaptation to climate. However, the influence and inheritance of mitochondrial DNA (mtDNA) are not usually considered in breeding programmes. In this study, we analysed the mtDNA profiles of cattle from Victoria (V...

journal_title：BMC genetics

authors： Srirattana K,McCosker K,Schatz T,St John JC

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:In humans, muscle-specific nicotinergic acetylcholine receptor (AChR) is a transmembrane protein with five different subunits, coded by CHRNA1, CHRNB, CHRND and CHRNG/CHRNE. The gamma subunit of AChR encoded by CHRNG is expressed during early foetal development, whereas in the adult, the γ subunit is replace...

journal_title：BMC genetics

authors： Kariminejad A,Almadani N,Khoshaeen A,Olsson B,Moslemi AR,Tajsharghi H

更新日期：2016-05-31 00:00:00

abstract：BACKGROUND:The Glued gene of Drosophila melanogaster encodes the homologue of the vertebrate p150Glued subunit of dynactin. The Glued1 mutation compromises the dynein-dynactin retrograde motor complex and causes disruptions to the adult eye and the CNS, including sensory neurons and the formation of the giant fiber sys...

journal_title：BMC genetics

authors： Ma L,Johns LA,Allen MJ

更新日期：2009-11-30 00:00:00

abstract：BACKGROUND:Yami and Ivatan islanders are Austronesian speakers from Orchid Island and the Batanes archipelago that are located between Taiwan and the Philippines. The paternal genealogies of the Yami tribe from 1962 monograph of Wei and Liu were compared with our dataset of non-recombining Y (NRY) chromosomes from the ...

journal_title：BMC genetics

authors： Loo JH,Trejaut JA,Yen JC,Chen ZS,Lee CL,Lin M

更新日期：2011-01-31 00:00:00

abstract：BACKGROUND:Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a small proportion of all colorectal cancer cases. The aim of this study was to identify the genetic background in a family suggested to segregate a dominant cancer syndrome with a high risk of...

journal_title：BMC genetics

authors： Thutkawkorapin J,Picelli S,Kontham V,Liu T,Nilsson D,Lindblom A

更新日期：2016-02-13 00:00:00

abstract：BACKGROUND:Genotyping technologies enable us to genotype multiple Single Nucleotide Polymorphisms (SNPs) within selected genes/regions, providing data for haplotype association analysis. While haplotype-based association analysis is powerful for detecting untyped causal alleles in linkage-disequilibrium (LD) with neigh...

journal_title：BMC genetics

authors： Yang Y,Li SS,Chien JW,Andriesen J,Zhao LP

更新日期：2008-12-22 00:00:00

abstract：BACKGROUND:Genome-wide investigation of molecular mechanisms for high-altitude adaptation has attracted great attention in the last few years. In order to understand the contribution of gene expression level variations to high-altitude adaptation in Asiatic toads (Bufo gargarizans), we implemented a reciprocal transpla...

journal_title：BMC genetics

authors： Yang W,Qi Y,Lu B,Qiao L,Wu Y,Fu J

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Compared to model-based approaches, nonparametric methods for quantitative trait loci mapping are more robust to deviations in distributional assumptions. In this study, we modify a nonparametric regression method and the "contrast function"- based regression method to analyze total cholesterol level in the ...

journal_title：BMC genetics

authors： Ghosh S,Bertelsen S,Reich T

更新日期：2003-12-31 00:00:00

abstract：BACKGROUND:Epidemiological studies have indicated that obesity and low high-density lipoprotein (HDL) levels are strong cardiovascular risk factors, and that these traits are inversely correlated. Despite the belief that these traits are correlated in part due to pleiotropy, knowledge on specific genes commonly affecti...

journal_title：BMC genetics

authors： Arya R,Lehman D,Hunt KJ,Schneider J,Almasy L,Blangero J,Stern MP,Duggirala R,Framingham Heart Study.

更新日期：2003-12-31 00:00:00

abstract：BACKGROUND:Discerning the traits evolving under neutral conditions from those traits evolving rapidly because of various selection pressures is a great challenge. We propose a new method, composite selection signals (CSS), which unifies the multiple pieces of selection evidence from the rank distribution of its diverse...

journal_title：BMC genetics

authors： Randhawa IA,Khatkar MS,Thomson PC,Raadsma HW

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:Linkage maps are essential tools for the study of several topics in genome biology. High density linkage maps for the porcine autosomes have been constructed exploiting the high density data provided by the PorcineSNP60 BeadChip. However, a high density SSCX linkage map has not been reported up to date. The ...

journal_title：BMC genetics

authors： Fernández AI,Muñoz M,Alves E,Folch JM,Noguera JL,Enciso MP,Rodríguez Mdel C,Silió L

更新日期：2014-12-20 00:00:00

abstract：BACKGROUND:The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigr...

journal_title：BMC genetics

authors： Li K,Geng J,Qu J,Zhang Y,Hu S

更新日期：2010-11-10 00:00:00

abstract：:A thorough genetic mapping study was performed to identify predisposing genes for alcoholism dependence using the Collaborative Study on the Genetics of Alcoholism (COGA) data. The procedure comprised whole-genome linkage and confirmation analyses, single locus and haplotype fine mapping analyses, and gene x environme...

journal_title：BMC genetics

authors： Yang HC,Chang CC,Lin CY,Chen CL,Lin CY,Fann CS

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:The use of pooled DNA on SNP microarrays (SNP-MaP) has been shown to be a cost effective and rapid manner to perform whole-genome association evaluations. While the accuracy of SNP-MaP was extensively evaluated on the early Affymetrix 10 k and 100 k platforms, there have not been as many similarly comprehens...

journal_title：BMC genetics

authors： Anantharaman R,Chew FT

更新日期：2009-12-14 00:00:00

abstract：BACKGROUND:The Mitotic Exit Network (MEN) proteins - including the protein kinase Cdc15 and the protein phosphatase Cdc14 - are essential for exit from mitosis in Saccharomyces cerevisiae. To identify downstream targets of the MEN, we sought telophase arrest bypassed (tab) mutations that bypassed the essential requirem...

journal_title：BMC genetics

authors： Shou W,Deshaies RJ

更新日期：2002-03-12 00:00:00

abstract：BACKGROUND:The Sapsaree is a breed of dog (Canis familiaris) native to Korea, which became perilously close to extinction in the mid-1980s. However, with systematic genetic conservation and restoration efforts, this breed was rescued from extinction and population sizes have been gradually increasing over the past few ...

journal_title：BMC genetics

authors： Gajaweera C,Kang JM,Lee DH,Lee SH,Kim YK,Wijayananda HI,Kim JJ,Ha JH,Choi BH,Lee SH

更新日期：2019-08-05 00:00:00

abstract：BACKGROUND:The establishment of the bisexual fertile fish hybrid lineage including the allodiploid and allotetraploid hybrids, from interspecific hybridization of red crucian carp (Carassius auratus red var. 2n = 100, 2n = AA) (♀) × common carp (Cyprinus carpio L. 2n = 100, 2n = BB) (♂), provided a good platform to inv...

journal_title：BMC genetics

authors： Zhang C,Ye L,Chen Y,Xiao J,Wu Y,Tao M,Xiao Y,Liu S

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:A typical genetical genomics experiment results in four separate data sets; genotype, gene expression, higher-order phenotypic data and metadata that describe the protocols, processing and the array platform. Used in concert, these data sets provide the opportunity to perform genetic analysis at a systems le...

journal_title：BMC genetics

authors： Druka A,Druka I,Centeno AG,Li H,Sun Z,Thomas WT,Bonar N,Steffenson BJ,Ullrich SE,Kleinhofs A,Wise RP,Close TJ,Potokina E,Luo Z,Wagner C,Schweizer GF,Marshall DF,Kearsey MJ,Williams RW,Waugh R

更新日期：2008-11-18 00:00:00

abstract：BACKGROUND:Trait variances among genotype groups at a locus are expected to differ in the presence of an interaction between this locus and another locus or environment. A simple maximum test on variance heterogeneity can thus be used to identify potentially interacting single nucleotide polymorphisms (SNPs). RESULTS:...

journal_title：BMC genetics

authors： Hothorn LA,Libiger O,Gerhard D

更新日期：2012-07-18 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) have crucial roles in various biological regulatory processes. However, the study of lncRNAs is limited in woody plants. Catalpa bungei is a valuable ornamental tree with a long cultivation history in China, and a deeper understanding of the floral transition mechanism in C. bu...

journal_title：BMC genetics

authors： Wang Z,Zhu T,Ma W,Wang N,Qu G,Zhang S,Wang J

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:The Gpnmb gene encodes a transmembrane protein whose function(s) remain largely unknown. Here, we assess if a mutant allele of Gpnmb confers susceptibility to glaucoma by altering immune functions. DBA/2J mice have a mutant Gpnmb gene and they develop a form of glaucoma preceded by a pigment dispersing iris ...

journal_title：BMC genetics

authors： Anderson MG,Nair KS,Amonoo LA,Mehalow A,Trantow CM,Masli S,John SW

更新日期：2008-04-10 00:00:00

abstract：BACKGROUND:Alcoholism is a serious public health problem. It has both genetic and environmental causes. In an effort to gain understanding of the underlying genetic susceptibility to alcoholism, a long-term study has been undertaken. The Collaborative Study on the Genetics of Alcoholism (COGA) provides a rich source of...

journal_title：BMC genetics

authors： Falk CT

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype. Alternatively, Lasso penalized regression allows one to jointly model the relationship b...

journal_title：BMC genetics

authors： Arbet J,McGue M,Chatterjee S,Basu S

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:Congenital fibrosis of the extraocular muscles types 1 and 3 (CFEOM1/CFEOM3) are autosomal dominant strabismus disorders that appear to result from maldevelopment of ocular nuclei and nerves. We previously reported that most individuals with CFEOM1 and rare individuals with CFEOM3 harbor heterozygous mutatio...

journal_title：BMC genetics

authors： Chan WM,Andrews C,Dragan L,Fredrick D,Armstrong L,Lyons C,Geraghty MT,Hunter DG,Yazdani A,Traboulsi EI,Pott JW,Gutowski NJ,Ellard S,Young E,Hanisch F,Koc F,Schnall B,Engle EC

更新日期：2007-05-18 00:00:00