Biological effects of new-generation dialkyl phosphinate flame retardants and their hydrolysates in BALB/C mice.

abstract：:Being one of the notorious weed P. hysterophorus has invaded almost every part India and is the lead cause of skin allergies and severe dermatitis among farmers and rural population. It is an invasive obnoxious weed capable of surviving extreme environmental conditions and various parts of this plant are reported to c...

journal_title：Environmental toxicology

authors： Kaur M,Gupta KB,Thakur S,Kaur S,Dhiman M

更新日期：2020-11-01 00:00:00

abstract：:The genotoxic effects of a particular mixture of acetamiprid (Acm, neonicotinoid insecticide) and alpha-cypermethrin (alpha-cyp, pyrethroid insecticide) on human peripheral lymphocytes were examined in vitro by chromosomal aberrations (CAs), sister chromatid exchange (SCE), and micronucleus (MN) tests. The human perip...

journal_title：Environmental toxicology

authors： Kocaman AY,Topaktaş M

更新日期：2010-04-01 00:00:00

abstract：:Linear alkylbenzene sulfonate (LAS) is an anionic surfactant commonly used in cleaning agents such as laundry detergents. Trace amounts of LAS are released into environmental waters after processing in wastewater treatment plants after the use of this chemical. Acute toxicity of LAS has been well-studied using various...

journal_title：Environmental toxicology

authors： Tasaki J,Nakayama K,Shimizu I,Yamada H,Suzuki T,Nishiyama N,Yamane M

更新日期：2017-01-01 00:00:00

abstract：:Trichloroethylene (TCE) is ubiquitous in our living environment, and prenatal exposure to TCE is reported to cause congenital heart disease in humans. Although multiple studies have been performed using animal models, they have limited value in predicting effects on humans due to the unknown species-specific toxicolog...

journal_title：Environmental toxicology

authors： Jiang Y,Wang D,Zhang G,Wang G,Tong J,Chen T

更新日期：2016-11-01 00:00:00

abstract：:We hypothesized that chronic exposure to arsenic would deplete the reduced glutathione (GSH) and methionine in vivo, thereby impair the methylation capacity of inorganic arsenic (iAs) ingested. Our experiment was designed to explore the effects of exogenous GSH and methionine on arsenic methylation in mice exposed to ...

journal_title：Environmental toxicology

authors： Jin Y,Zhao F,Zhong Y,Yu X,Sun D,Liao Y,Lv X,Li G,Sun G

更新日期：2010-08-01 00:00:00

abstract：:Polybrominated diphenyl ethers (PBDEs) are ubiquitous and prolific contaminant in both the abiotic and biotic environment because of the wide industrial applications of these chemicals. In the present study, the effects of 2,2',4,4'-tetrabrominateddiphenyl ether (BDE-47) and 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE...

journal_title：Environmental toxicology

authors： Meng S,Chen X,Gyimah E,Xu H,Chen J

更新日期：2020-11-01 00:00:00

abstract：:Cardiomyocyte apoptosis is the major risk factor for the development of heart failure (HF). The purpose of this study was to evaluate the effects of Gamma-aminobutyric acid (GABA) tea on hypertension-induced cardiac apoptotic pathways in spontaneously hypertensive rats (SHR). In order to reveal the mechanisms, 36 male...

journal_title：Environmental toxicology

authors： Chen BC,Hung MY,Wang HF,Yeh LJ,Pandey S,Chen RJ,Chang RL,Viswanadha VP,Lin KH,Huang CY

更新日期：2018-07-01 00:00:00

abstract：:Kupffer cells (KCs) are important in hepatic homeostasis and responses to xenobiotics. KCs are activated on interaction with endotoxin, releasing cytokines, and reactive oxygen species normally associated with increased gene expression, cellular growth, or hepatic injury. Ethanol-induced endotoxemia is one means of KC...

journal_title：Environmental toxicology

authors： Owumi SE,Corthals SM,Uwaifo AO,Kamendulis LM,Klaunig JE

更新日期：2014-08-01 00:00:00

abstract：:The present study was designed to understand the effects of sublethal concentrations of dichlorvos (DIC) on hematological constituent [red blood corpuscles, white blood corpuscles (WBC), mean cell volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, platelet counts, hemoglobin and hematocrit...

journal_title：Environmental toxicology

authors： Celik I,Yilmaz Z,Turkoglu V

更新日期：2009-04-01 00:00:00

abstract：:Triclosan, a commonly used antimicrobial compound, has been measured in aquatic systems worldwide. This study exposed marine species to triclosan to examine effects primarily on survival and to investigate the formation of the degradation product, methyl-triclosan, in the estuarine environment. Acute toxicity was asse...

journal_title：Environmental toxicology

authors： Delorenzo ME,Keller JM,Arthur CD,Finnegan MC,Harper HE,Winder VL,Zdankiewicz DL

更新日期：2008-04-01 00:00:00

abstract：:Survival of juvenile freshwater mussels (Echyridella menziesii (Gray, 1843) formerly known as Hyridella menziesi) and crayfish (Paranephrops planifrons, White, 1842) decreased after four days exposure to microcystin-containing cell-free extracts (MCFE) of Microcystis sp. at concentrations typical of severe cyanobacter...

journal_title：Environmental toxicology

authors： Clearwater SJ,Wood SA,Phillips NR,Parkyn SM,Van Ginkel R,Thompson KJ

更新日期：2014-05-01 00:00:00

abstract：:T-2 toxin is the most toxic among mycotoxins and poses a potential health hazard for both humans and animals. At high doses, T-2 toxin can cause shock-like syndrome that can result in death. We evaluated the effect of time course and route of exposure on hepatic oxidative damage in mice and it is only such study so fa...

journal_title：Environmental toxicology

authors： Chaudhary M,Bhaskar AS,Rao PV

更新日期：2015-01-01 00:00:00

abstract：:To evaluate the allergic effect of airborne particulate matter (PM) on the airway, separated soluble supernatant (Sup) and insoluble precipitate (Pre) in suspended PM were inoculated into NC/Nga mice with a high sensitivity for mite allergens. Sup, Pre, or both Sup and Pre with or without pronase treatment were inocul...

journal_title：Environmental toxicology

authors： Ogino K,Takahashi N,Kubo M,Takeuchi A,Nakagiri M,Fujikura Y

更新日期：2014-06-01 00:00:00

abstract：:Benchmark dose (BMD) and the lower confidence limit on the benchmark dose (BMDL) of blood lead were estimated to explore the biologic exposure limits for renal dysfunction caused by lead. One hundred thirty-five workers from one storage battery plant were selected as lead exposure group while 143 mechanics as the cont...

journal_title：Environmental toxicology

authors： Lin T,Tai-Yi J

更新日期：2007-06-01 00:00:00

abstract：:Andrographolide, the main bioactive component of the medicinal plant Andrographis paniculata, has been shown to possess potent anti-inflammatory activity. Endothelin 1 (ET-1), a potent vasoconstrictor peptide produced by vascular endothelial cells, displays proinflammatory property. Hypoxia-inducible factor 1α (HIF-1α...

journal_title：Environmental toxicology

authors： Lin HC,Su SL,Lu CY,Lin AH,Lin WC,Liu CS,Yang YC,Wang HM,Lii CK,Chen HW

更新日期：2017-03-01 00:00:00

abstract：:In this study, toxic effects of the cypermethrin in Allium cepa L. cells were investigated. For this aim, we investigated the changes in pigment contents, antioxidant enzymes, mitotic index and chromosomal abnormalities as indicators of toxicity. The seeds were treated with different doses (1.5, 3.0, 6.0 ppm) of cyper...

journal_title：Environmental toxicology

authors： Çavuşoğlu K,Kaya A,Yilmaz F,Yalçin E

更新日期：2012-10-01 00:00:00

abstract：:di-N-butylphthalate (DBP) is a ubiquitous environmental pollutant used for plastic coating and in the cosmetics industry. It has toxic effects on body health, especially the male reproductive system. Here, we investigated the effects of DBP on the male reproductive system of pubertal mice and explored the protective r...

journal_title：Environmental toxicology

authors： Jiang XP,Tang JY,Xu Z,Han P,Qin ZQ,Yang CD,Wang SQ,Tang M,Wang W,Qin C,Xu Y,Shen BX,Zhou WM,Zhang W

更新日期：2017-07-01 00:00:00

abstract：:The aim of this study was to examine the occurrence of endocrine disruption close to sewage treatment plant effluent discharges along the Finnish Baltic Sea coast using a set of reproductive biomarkers present in adult three-spined stickleback (Gasterosteus aculeatus). Possible variation and sensitivity of the biomark...

journal_title：Environmental toxicology

authors： Björkblom C,Mustamäki N,Olsson PE,Katsiadaki I,Wiklund T

更新日期：2013-04-01 00:00:00

abstract：:Nickel oxide nanoparticles (nano NiO) could induce hepatocyte apoptosis, while its potential mechanisms are unclear. This study aimed to explore the role of endoplasmic reticulum (ER) stress pathways in hepatocyte apoptosis induced by nano NiO. Male Wistar rats were administrated with nano NiO (0.015, 0.06, and 0.24 m...

journal_title：Environmental toxicology

authors： Chang X,Liu F,Tian M,Zhao H,Han A,Sun Y

更新日期：2017-12-01 00:00:00

abstract：:Melanoma is the leading cause of death from skin disease due to its propensity for metastasis. Studies have shown that integrin-mediated focal adhesion kinase (FAK) signal pathway is implicated in cell proliferation, survival and metastasis of tumor cells. Our previous results indicated that diallyl trisulfide (DATS) ...

journal_title：Environmental toxicology

authors： Wang HC,Chu YL,Hsieh SC,Sheen LY

更新日期：2017-11-01 00:00:00

abstract：:The present study was designed to understand the oxidative stress potential of fenthion, an organophosphate (OP) pesticide and its involvement in glutathione metabolism modulated buthionine sulfoximine (BSO, 50 mg/kg) and N-acetylcysteine (NAC, 100 mg/kg) in the brain of fish, Oreochromis niloticus. A sublethal fenthi...

journal_title：Environmental toxicology

authors： Piner P,Sevgiler Y,Uner N

更新日期：2007-12-01 00:00:00

abstract：:Crude extract of Rheum palmatum L (CERP) has been used to treat different diseases in the Chinese population for decades. In this study, we investigated the effects of CERP on LS1034 human colorectal cancer cells in vitro and also examined possible mechanisms of cell death. Flow cytometric assays were used to measure ...

journal_title：Environmental toxicology

authors： Ma YS,Hsu SC,Weng SW,Yu CC,Yang JS,Lai KC,Lin JP,Lin JG,Chung JG

更新日期：2014-09-01 00:00:00

abstract：:Previous studies indicate that exposure to perfluorooctanesulfonate (PFOS), a ubiquitous and highly persistent environmental contaminant, induces immunotoxicity in mice. However, few studies have specifically assessed the effects of PFOS on inflammation. This study utilized a standard 60-day oral exposure period to as...

journal_title：Environmental toxicology

authors： Dong GH,Zhang YH,Zheng L,Liang ZF,Jin YH,He QC

更新日期：2012-05-01 00:00:00

abstract：:In the current study, the toxicological mechanisms of microcystin-LR and its disadvantageous effects on Daphnia magna were examined. Survival rate, number of newborn, activity of several important enzymes [glutathione S-transferase (GST), lactate dehydrogenase (LDH), phosphatases, and glutathione], accumulated microcy...

journal_title：Environmental toxicology

authors： Chen W,Song L,Ou D,Gan N

更新日期：2005-06-01 00:00:00

abstract：:Toxins in cyanobacteria are a recognized risk in the treatment of drinking-water treatment. Cyanotoxins can occur in two modifications: cell bound and dissolved in water. The process of toxin release may occur naturally, but it also may be induced through the processes of drinking-water treatment. Both causes of relea...

journal_title：Environmental toxicology

authors： Schmidt W,Willmitzer H,Bornmann K,Pietsch J

更新日期：2002-01-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults and the major cause of mortality in urological cancer. Most patients with RCC are asymptomatic until the disease is advanced and unresectable. In this situation, systemic therapy with immunotherapy or molecularly targeted therapy agents play...

journal_title：Environmental toxicology

authors： Wu SW,Chen PN,Lin CY,Hsieh YS,Chang HR

更新日期：2017-07-01 00:00:00

abstract：:Human exposure to bisphenol A (BPA) could favor obesity and related metabolic disorders such as hepatic steatosis. Investigations in rodents have shown that these deleterious effects are observed not only when BPA is administered during the adult life but also with different protocols of perinatal exposure. Whether pe...

journal_title：Environmental toxicology

authors： Bucher S,Jalili P,Le Guillou D,Begriche K,Rondel K,Martinais S,Zalko D,Corlu A,Robin MA,Fromenty B

更新日期：2017-03-01 00:00:00

abstract：:Several estuaries along the Pacific Ocean coast of North America were identified recently as having elevated 4-nonylphenol (4-NP) in sediments and biota, raising concerns about reproductive impacts for wildlife given 4-NP's established estrogenic activity as an endocrine-disrupting compound. Here we characterize 4-NP ...

journal_title：Environmental toxicology

authors： Johnson KM,Lema SC

更新日期：2017-05-01 00:00:00

abstract：:The toxicity of petroleum hydrocarbons to marine aquatic organisms has been widely investigated; however, the effects on freshwater environments have largely been ignored. Selected biomarkers were measured in a freshwater species, the crimson-spotted rainbowfish (Melanotaenia fluviatilis). Fish were exposed to either ...

journal_title：Environmental toxicology

authors： Pollino CA,Holdway DA

更新日期：2003-02-01 00:00:00

abstract：:Avian vacuolar myelinopathy (AVM) is a neurological disease affecting bald eagles (Haliaeetus leucocephalus), American coots (Fulica americana), waterfowl, and other birds in the southeastern United States. The cause of the disease is unknown, but is thought to be a naturally produced toxin. AVM is associated with aqu...

journal_title：Environmental toxicology

authors： Wiley FE,Twiner MJ,Leighfield TA,Wilde SB,Van Dolah FM,Fischer JR,Bowerman WW

更新日期：2009-08-01 00:00:00