Abstract：
:Congenital cataract is the most common cause of the visual disability and blindness in childhood. This study aimed to identify gene mutations responsible for autosomal dominant congenital cataract (ADCC) in a Chinese family using next-generation sequencing technology. This family included eight unaffected and five affected individuals. After complete ophthalmic examinations, the blood samples of the proband and two available family members were collected. Then the whole exome sequencing was performed on the proband and Sanger sequencing was applied to validate the causal mutation in the two family members and control samples. After the whole exome sequencing data were filtered through a series of existing variation databases, a heterozygous mutation c.499T journal_name journal_title authors doi subject pub_date pages eissn issn journal_volume pub_type
abstract：Background:Chromatic contrast may affect stereopsis. Daltonism is a common color deficiency in which the colors red and green are incorrectly detected. The aim of this study was to evaluate the stereoacuity of color-defective individuals presented with color symbols that they see defectively. Methods:Ten students diag...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/1926736
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:Popular beliefs exert an impact of lunar phases on elective surgery. The aim of our study was to evaluate potential correlations between complications in cataract surgery and the phases of the moon during its passage through the zodiac and Fridays that fall on the 13th. METHODS:Patients with complications duri...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/1946527
更新日期：2017-01-01 00:00:00
abstract：:Purpose. To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them with those obtained with multimodal imaging. Methods. A series of consecutive patients diagnosed with CSC, underwent OCTA and multimodal imaging, including spectral domai...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/134783
更新日期：2015-01-01 00:00:00
abstract：:Purpose. To construct an inexpensive, convenient, and portable attachment for smartphones for the acquisition of still and live retinal images. Methods. A small optical device based on the principle of direct ophthalmoscopy was designed to be magnetically attached to a smartphone. Representative images of normal and p...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/823139
更新日期：2015-01-01 00:00:00
abstract：:The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuit...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/5717932
更新日期：2016-01-01 00:00:00
abstract：:Introduction. Retinoblastoma is the most common primary intraocular neoplasm in children. With the advances in medicine, the armamentarium of available treatment modalities has grown. Intraarterial chemotherapy is a relatively new treatment method with promising outcomes. The purpose of this literature review is to ev...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2020/3638410
更新日期：2020-01-24 00:00:00
abstract：OBJECTIVES:To analyse the changes of ocular haemodynamics and morphology in Chinese patients with internal carotid artery (ICA) stenosis in the current study. METHODS:A retrospective case-control study was conducted with 219 patients. The haemodynamic characteristics, the calibre of retinal vessels, and the subfoveal ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/1842176
更新日期：2017-01-01 00:00:00
abstract：Purpose:Evaluation of the indications, anatomical and functional results, and complications of total penetrating keratoplasty (TPK) in disorders involving whole cornea. Materials and Methods:We analyzed outcomes of the surgical treatment of 47 eyes of 46 patients that underwent TPK. Indications were infectious keratit...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/9580292
更新日期：2018-04-19 00:00:00
abstract：:This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. Forty-two consecutive patients undergoing pars plana vitrectomy (PPV) for PDR were included in this cross-sectional study. The aqueous humor ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/4831967
更新日期：2019-07-17 00:00:00
abstract：Purpose:To evaluate the clinical classification and characteristics of hereditary optic neuropathy patients in a single center in China. Method:Retrospective case study. Patients diagnosed with hereditary optic neuropathy between January 2014 and December 2015 in the neuro-ophthalmology division in Shanghai Eye and EN...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/6186052
更新日期：2017-01-01 00:00:00
abstract：Background:Bardet-Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. Materials and Methods:Two families were recruited in this study. Family A was a four-generation family with four affected and 15...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2021/6751857
更新日期：2021-01-06 00:00:00
abstract：:Purpose. Ischemic central retinal vein occlusion (CRVO) eyes are at high risk of developing neovascular glaucoma (NVG). Our purpose is to investigate the effect of anti-VEGF therapy for macular edema after CRVO on the development of neovascular glaucoma (NVG) in ischemic CRVO eyes. Methods. This is a retrospective cas...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2014/317694
更新日期：2014-01-01 00:00:00
abstract：Purpose:To investigate the effects of capsulotomy shape on the visual acuity and visual quality after neodymium: yttrium aluminum garnet laser capsulotomy. Methods:In this study, a total of 42 eyes from 35 patients with posterior capsule opacification were divided into the circular and cruciate groups. The corrected d...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/4153109
更新日期：2020-03-23 00:00:00
abstract：Objective:To report the 15-year trend in ophthalmic presentations to the emergency department (ED) at the only medical center in Lebanon that provides 24-hour ophthalmologic care. Methods:Retrospective review of 1967 patients presenting to the ED with eye-related complaints between September 1997 and August 1998 and b...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/4739865
更新日期：2018-03-13 00:00:00
abstract：Purpose:To analyse the correlation of myopia with physical exercise and sleep habits to explore the possible risk or protective factors of juvenile myopia. Methods:This study was a retrospective cross-sectional study. A total of 1831 students aged 11-18 years from five schools in Qingpu completed questionnaires from 2...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/2670153
更新日期：2020-07-25 00:00:00
abstract：:Purpose. To compare near, intermediate, and distance vision and quality of vision, when refractive rotational multifocal intraocular lenses with 3.0 diopters or diffractive multifocal intraocular lenses with 2.5 diopters near addition are implanted. Methods. 41 eyes of 41 patients in whom rotational +3.0 diopters near...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1395302
更新日期：2016-01-01 00:00:00
abstract：Purpose:To evaluate intraoperative complications and utilization of adjunctive devices between microscope and intracameral illuminations during cataract surgery in the elderly over 75 years. Design:A retrospective, consecutive, interventional case series Participants. Two hundred eighty-six eyes of 184 patients older ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/1594152
更新日期：2019-01-10 00:00:00
abstract：:Purpose. To report a new clinical finding related to Fabry disease. Methods. Fabry subjects were enrolled in the study, matched for age and sex with healthy individuals as a control group. This is a prospective review of all upper lid pictures taken for every subject at their last visit. A 4-step grading scale is prop...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/207573
更新日期：2013-01-01 00:00:00
abstract：Background:The advantage of using an autostereoscopic smartphone is that it can achieve 3D effects without the need for glasses. The purpose of this study was to evaluate whether this technology could be utilized to detect stereoacuity. Methods:An autostereoscopic smartphone was used to imitate Lang stereotest I & II,...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/1570309
更新日期：2019-10-31 00:00:00
abstract：Purpose:Bilateral choroidal ganglioneuroma is extremely rare, and no cases have been described in the literature. Multimodal images are crucial for its diagnosis. Here, we evaluated multimodal images in the early stage of choroidal ganglioneuroma. Methods:A 6-year-old boy was recruited who had experienced gradually pr...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/6231269
更新日期：2020-05-11 00:00:00
abstract：:Purpose. To compare dry eye disease following SMILE versus FS-LASIK. Design. Prospective, nonrandomised, observational study. Patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent SMILE and 43 eyes underwent FS-LASIK. Methods. Evaluation of dry eye disease was conducted preope...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/132417
更新日期：2015-01-01 00:00:00
abstract：:Methylglyoxal (MG) is an intermediate of glucose metabolism and the precursor of advanced glycation end products (AGEs) found in high levels in blood or tissue of diabetic patients. MG and AGEs are thought to play a major role in the pathogenesis of diabetic retinopathy. In order to determine if zebrafish is valuable ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/2746735
更新日期：2019-04-17 00:00:00
abstract：:Purpose. Randomized controlled trial aimed at comparing surgical outcomes in a group of patients suffering from hyperfunction of the inferior oblique (IO) muscle with abnormal head position (AHP). The surgical techniques being compared are Recession and (thread) Controlled Myotomy. Materials and Methods. The group of ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1725484
更新日期：2016-01-01 00:00:00
abstract：:Diabetic retinal complications, including macular edema (DME) and proliferative diabetic retinopathy (PDR), are the leading cause of new cases of blindness among adults aged 20-74. Chronic hyperglycemia, considered the underlying cause of diabetic retinopathy, is thought to act first through violation of the pericyte-...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/209538
更新日期：2012-01-01 00:00:00
abstract：:Quantitative measurement of the orbital soft tissue volume plays a very important role in the study of orbital diseases. The purpose of this study is to establish a computed tomography- (CT-) based three-dimensional (3D) reconstruction model and measure the orbital soft tissue volume in Chinese adults. We collected da...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/9721085
更新日期：2019-07-02 00:00:00
abstract：:We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge we...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/3438041
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. METHODS:Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2017/2915261
更新日期：2017-01-01 00:00:00
abstract：Purpose:To evaluate neurodegeneration in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy and to assess the possible role of systemic vascular complications in retinal changes. Methods:Sixty eyes of 60 patients with DM2 and without any signs of diabetic retinopathy and 60 eyes of 60 healthy co...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/1825819
更新日期：2019-08-07 00:00:00
abstract：:Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/8656301
更新日期：2016-01-01 00:00:00
abstract：:Purpose. To compare the surgically induced astigmatism from clear corneal and square posterior limbal incisions at the time of cataract surgery. Methods. Surgically induced astigmatism was calculated for a set of eyes after cataract surgery using a temporal 2.2 mm square posterior limbal incision. Results were compare...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2011/243170
更新日期：2011-01-01 00:00:00
