Abstract:
BACKGROUND:Many risk factors have been investigated in multiple sclerosis (MS); however, few studies have focused on the association between risk factors and the disease severity. The aim of our study was to evaluate the association between some of these risk factors and MS severity in a population sample of Iranian patients. METHODS:This cross-sectional study was conducted on 660 patients with MS. In addition to demographic variables, many potential risk factors were recorded. To compare the severity, progression index (PI) was calculated. This index is created by current Expanded Disability Status Scale (EDSS) /disease duration. RESULTS:Univariate analysis revealed that active smoking status is related with MS severity. (P-value = 0.012). Furthermore, our findings demonstrated that age at the disease onset [P < 0.001; OR = 1.05 (95% CI: 1.03-1.07)], female gender [P = 0.002; OR = 1.86 (95% CI: 1.24-2.77)] and marital status [P = 0.002; OR = 1.71 (95% CI: 1.21-2.41)] correlated with the severity of MS in the adjusted model. MS severity was observed to be related with high school and academic studies ([P = 0.004; OR = 0.56 (95% CI: 0.38-0.83)], [P = 0.001; OR = 0.52 (95% CI: 0.35-0.78)]) (Primary/secondary school studies are used as reference). Moreover, there was an association between MS severity and occupation (white collar, pink collar) ([P = 0.006; OR = 0.32 (95% CI: 0.14-0.73)], [P = 0.007; OR = 0.47 (95% CI: 0.27-0.81)]) (Student is used as reference). Furthermore, the results showed a significant correlation between vision and motor symptoms as an initial symptom and PI (P = 0.001, P = 0.025). CONCLUSION:Due to high cost of MS care and its moderate to severe disability, identification of factors influencing the MS severity is important. Our results demonstrated that the major modifiable factors related with MS severity in Iranian population, some protective and some promotive, were smoking, education, marital status and occupation. Prospective studies on larger scale are needed for further proof of these results.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Abbasi M,Nabavi SM,Fereshtehnejad SM,Ansari I,Zerafatjou N,Shayegannejad V,Mohammadianinejad SE,Farhoudi M,Noorian A,Razazian N,Abedini M,Faraji Fdoi
0161912/AIM.007subject
Has Abstractpub_date
2016-12-01 00:00:00pages
852-860issue
12eissn
1029-2977issn
1735-3947pii
007journal_volume
19pub_type
杂志文章abstract::Hydatidosis is an important zoonotic parasite disease in several herbivorous mammals. Human cystic echinococcosis (CE) caused by infection with larval stage of Echinococcus granulosus has been frequently reported from different organs. Here, we report the first case of a urinary echinococcosis in Iran with a pain in t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Tendon entrapment of the first dorsal compartment of the wrist, the de Quervain disease, is a common cause of wrist and hand pain and disability. A group of 50 consecutive patients operated for the treatment of de Quervain disease from 2003 through 2006 were prospectively studied to determine the variation i...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Septic arthritis is a fearful condition because of its mortality and the potentially late sequels on immature skeleton including limb shortening, osteomyelitis, destruction of joint surface, severe limitation of motion, and dislocation.This study was performed to reveal the final outcome of our patients and find out t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:The current WHO classification of hematologic malignancies defines distinct entities of myeloid disorders based on the presence of recurrent cytogenetic abnormalities. Diagnostic clonal chromosomal abnormalities provide important prognostic information and are among the most important factors in predicting i...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013168/AIM.005
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:Studies on gastric mucosal histological findings among first degree relatives (FDR) of gastric cancer (GC) patients are scarce. The aim is to evaluate the topography and the severity of gastritis among FDR of GC patients. DESIGN:A total of 989 subjects who were FDR of GC patients, ages 40-65 years underwent...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:010136/AIM.004
更新日期:2010-11-01 00:00:00
abstract::Effective prevention and early diagnostic strategies are the most important public health interventions in gastric cancer, which remains a common malignancy worldwide. Preventive strategies require identification and understanding of environmental risk factors that lead to carcinogenesis. Helicobacter pylori (H. pylor...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:013166/AIM.0010
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Wrong beliefs about risky actions such as sunbathing and tanning are common due to media advertisements or general lack of knowledge. This work has focused on the knowledge and attitude of a group of citizens in Tehran, Iran and the protective actions they take regarding undesirable effects of the sun. M...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:011142/AIM.0011
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:In Iran, zoonotic and anthroponotic cutaneous leishmaniasis (CL) are caused by Leishmania major and L. tropica respectively. Despite extensive studies, no effective therapies have ever been reported for CL. The main objective of this research was to determine and compare the three different protocols for tre...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:10.34172/aim.2020.98
更新日期:2020-11-01 00:00:00
abstract::Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC. Exposure to polycyclic aromatic hydrocarbons (PAHs) has been suggested as a risk factor for developing ESCC. In this paper we will...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:0121511/AIM.0013
更新日期:2012-11-01 00:00:00
abstract::Acute hemorrhagic edema of infancy is a distinctive, cutaneous small vessel leukocytoclastic vasculitis of young children with dramatic characteristic skin findings. It is characterized by low- grade fever, erythematous edema, and purpuric lesions mainly on the face and extremities. Visceral involvement is uncommon, a...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:08111/AIM.0019
更新日期:2008-01-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-10-01 00:00:00
abstract::Despite all the problems caused by the imposed war, sanctions and accidents after the Islamic Revolution, materializing primary health care (PHC) in Iran through establishing the National Health Network (NHN) has had substantial gains. Many health indicators in Iran have undergone significant changes. As an example, t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have specific dietary needs due to recommended dietary restrictions. However, there is no specific index for evaluating the quality of diet in patients with CKD. OBJECTIVE: To define and compare three specific diet quality indices in patients with CKD. METHODS:Tw...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Thalassemia major and its treatment by stem cell transplantation can have deleterious effects on bone integrity. This study assesses the adverse effects of transplantation on growing bones of pediatric thalassemic patients. METHODS:Bone mineral density (BMD) of 20 patients from three thalassemia classes who...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013162/AIM.008
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:The need for mental health care among children and adolescents in Iran, as in other low and middle income countries (LAMIC) remains mostly unmet. In this paper, we sought to provide an overview of the extent of unmet need and mental health services in Iran. We also aimed to propose approaches to address this...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0161911/AIM.0010
更新日期:2016-11-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:10.34172/aim.2020.08
更新日期:2020-04-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012158/AIM.0014
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Oxidative stress is involved in the pathophysiology of diabetes mellitus. METHODS:In the present study, 68 patients with type 2 diabetes mellitus and 31 clinically healthy individuals were evaluated. The patients were divided into two groups. Group 1 included 29 patients without diabetic complications and g...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:This research aims to determine the mental health status of population aged 15 and over in the province of Razavi Khorasan in 2015. METHODS:The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Razavi Khorasan in Iran. An estimated sample size o...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-11-01 00:00:00
abstract::Many families are directly involved in caring of their children with the lifelong autistic spectrum disorders. Sometimes, they are the victims of their children's behaviors. The family, including siblings, may have to explain the children's behaviors to others. Their mothers have poorer mental health with difficulties...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Suicide is among the top 20 leading causes of death globally in all age groups and it is still a significant social and public health problem. METHODS:Data on suicide deaths in 1987-2011 were extracted from the Turkish Statistical Institute mortality dataset based on ICD-9 and ICD-10 codes. The temporal tre...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:015186/AIM.006
更新日期:2015-06-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012157/AIM.0011
更新日期:2012-07-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151801/AIM.0015
更新日期:2015-01-01 00:00:00
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journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2018-09-01 00:00:00
abstract::Intravenous drug abuse is an increasing social and health problem. Repeated injuries to the veins, injection of some types of insoluble substances, and needle sharing habits result in various complications. Increasing incidence of major vascular complications has been reported worldwide. The objective of this study wa...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:07104/AIM.0018
更新日期:2007-10-01 00:00:00
abstract:INTRODUCTION:Transfusion of packed red blood cells (pRBC) with appropriate indications is not only important for patient safety and well-being but is also crucial for proper utilization of resources and health care-related cost reduction. We aimed to investigate the clinical appropriateness of blood transfusion in Shar...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0172002/AIM.004
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Growth is an increase in the physical dimensions and its result is a quantitative change in the body. Development is a progressive increase in the skills and functional capacity of a child and its result is a qualitative change in a child's function. METHODS:This investigation was a descriptive, decompositi...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Placental mesenchymal dysplasia is a rare condition of the placenta and its true incidence and underlying cause has remained unknown till now due to its rarity. Its accurate diagnosis is essential, because placental mesenchymal dysplasia is usually compatible with a good fetal and maternal outcome. A precise ultrasono...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013169/AIM.0013
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Successful isolation of mesenchymal stem cells from waste tissues might be extremely promising for developing stem cell-based therapies. This study aimed to explore whether cells retrieved from teeth extracted due to advanced periodontal disease present mesenchymal stem cell-like properties. METHODS:Pulp ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:015184/AIM.004
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:The standard treatment for decompensated liver cirrhosis is liver transplantation. However, it has several limitations. Recent animal studies suggest that bone marrow stem cell transplantation can lead to regression of liver fibrosis. The objective of this study was to determine the safety and feasibility of...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:07104/AIM.008
更新日期:2007-10-01 00:00:00