An elderly male with tingly legs and a heavy heart: Persisting with the diagnosis!

Abstract:

:Pursuing a diagnosis despite a negative nerve biopsy report requires a strong clinical conviction. Paying attention to clinical details and a diligent review of medical records is needed to solve cases in which the diagnosis is not obvious despite numerous tests. We present once such case of an elderly man with chronic diarrhea, weight loss, and peripheral neuropathy and elaborate on a step by step basis on how the clinical thought process evolved after sifting through the reports of scan and tests done during his work up.

journal_name

Ann Indian Acad Neurol

authors

Kharadi M,Harsha SV,Gopalakrishnan G,Karthick GA,Raj V,Kannan S

doi

10.4103/0972-2327.194413

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

444-447

issue

4

eissn

0972-2327

issn

1998-3549

pii

AIAN-19-444

journal_volume

19

pub_type

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    abstract:Background:Rules and regularities are embedded in all the language structures. Extracting these helps in speech-language acquisition and processing. Sentence processing relies on transitional probability of the dependencies and its distance which are present within the sentence. Aim:To investigate the effect of distan...

    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/aian.AIAN_510_20

    authors: Darshan HS,Goswami SP

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  • Predictors of Outcome in Children with Status Epilepticus during Resuscitation in Pediatric Emergency Department: A Retrospective Observational Study.

    abstract:OBJECTIVES:To study the clinical profile and predictors of outcome in children with status epilepticus (SE) during resuscitation in pediatric emergency department. MATERIALS AND METHODS:This retrospective study was carried out in a tertiary care teaching hospital. Admission and resuscitation data of children, aged bet...

    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/aian.AIAN_369_16

    authors: Santhanam I,Yoganathan S,Sivakumar VA,Ramakrishnamurugan R,Sathish S,Thandavarayan M

    更新日期:2017-04-01 00:00:00

  • Treatment-related Fluctuations in Guillain Barre Syndrome and the Conundrum of Additional Cycles of Plasmapheresis.

    abstract:Introduction:In Guillain Barre syndrome (GBS), worsening of weakness or disability after initial period of recovery or stabilization is described as treatment-related fluctuations (TRF). Aim:This study aims to describe the clinical characteristics and outcome of six patients with GBS and TRF. Patients and Methods:Six...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/aian.AIAN_242_17

    authors: Ramakrishnan S,Mustare V,Philip M,Thennarasu K,Periyavan S

    更新日期:2017-10-01 00:00:00

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    abstract::Medical education in India is expected to undergo a significant reform after the introduction of the National Medical Commission Act. Single, nationwide National Exit Test (NEXT) is an essential provision under this act, which will be implemented during the next three years. It aims to bring about uniformity in the mi...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 社论

    doi:10.4103/aian.AIAN_478_19

    authors: Ranjan P,Ranjan R,Kumar M

    更新日期:2020-03-01 00:00:00

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    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/0972-2327.78045

    authors: Singh P,Joshua AM,Ganeshan S,Suresh S

    更新日期:2011-01-01 00:00:00

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    abstract:OBJECTIVES:The aim of this study was to assess the effect of sodium valproic acid (SVA) on the sleep quality of patients with juvenile myoclonic epilepsy (JME). MATERIALS AND METHODS:Standardized sleep questionnaires viz. Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI) were administered to 30 ...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/0972-2327.165472

    authors: Nayak C,Sinha S,Ramachandraiah CT,Nagappa M,Thennarasu K,Taly AB,Satishchandra P

    更新日期:2015-10-01 00:00:00

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    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/0972-2327.128554

    authors: Saleem S,Yousuf I,Gul A,Gupta S,Verma S

    更新日期:2014-01-01 00:00:00

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    abstract:Background and Aims:Intracranial atherosclerotic disease (ICAD) is common in the Asian population, but less studied in South Asians compared to East Asians. We compared risk factors, treatments, and outcomes among consecutive patients with symptomatic ICAD from India with a mixed-ethnic cohort from Chicago, Illinois. ...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/aian.AIAN_549_19

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    更新日期:2020-05-01 00:00:00

  • Acute Ischemic Stroke Treatment Using Mechanical Thrombectomy: A Study of 137 Patients.

    abstract:BACKGROUND:Mechanical thrombectomy (MT) is the most effective treatment in large vessel occlusion (LVO). We have analyzed our initial experience of MT of 137 patients in anterior circulation (AC) and posterior circulation (PC) LVO using Solitaire stent retriever device. METHODS:Retrospective cohort analysis of 112 AC ...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/aian.AIAN_158_17

    authors: Singh RK,Chafale VA,Lalla RS,Panchal KC,Karapurkar AP,Khadilkar SV,Ojha PK,Godge Y,Singh RK,Benny R

    更新日期:2017-07-01 00:00:00

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    doi:10.4103/0972-2327.58277

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    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/0972-2327.132625

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    更新日期:2014-04-01 00:00:00

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    abstract::The authors report a family from Punjab (India) with 10 members having benign familial neonatal convulsions (also known as benign familial neonatal seizures) in two generations. This disorder is quite rare. The clinical presentation of index case along with the findings of computed tomography of the brain and electroe...

    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/0972-2327.40227

    authors: Singh H,Raj R

    更新日期:2008-01-01 00:00:00

  • "Dry" and "wet" beriberi mimicking critical illness polyneuropathy.

    abstract::Three cases with manifestations of right heart failure, shock, metabolic acidosis, and renal failure in varying combination were admitted with paraparesis. Nerve conduction study suggested predominantly motor and mainly axonal type of neuropathy. Rapid reversal of shock, acidosis, and multi-organ dysfunction with time...

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    更新日期:2018-10-01 00:00:00

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    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/0972-2327.74185

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    更新日期:2010-10-01 00:00:00

  • Chronic relapsing inflammatory optic neuropathy.

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    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/0972-2327.61280

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    更新日期:2010-01-01 00:00:00

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    abstract::During the colloquium on drug-resistant epilepsy (DRE) at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore on August 16-18, 2013, a number of presentations were made on the surgically remediable lesional epilepsy syndromes, presurgical evaluation, surgical techniques, neuropathology of drug r...

    journal_title:Annals of Indian Academy of Neurology

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    abstract:BACKGROUND:Neuromyelitis optica (NMO) is an immune-mediated inflammatory demyelinating disorder of the central nervous system with a predilection for the optic nerves and the spinal cord. Immunopathological evidence suggests that the target antigen of the disease is aquaporin-4. An IgG antibody against this protein has...

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    doi:10.4103/0972-2327.116945

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    journal_title:Annals of Indian Academy of Neurology

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    doi:10.4103/0972-2327.91953

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  • Is Dementia in Parkinson' Disease Related to Chronic Stress, Anxiety, and Depression?

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    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/aian.AIAN_341_18

    authors: Pal A,Pegwal N,Behari M,Sharma R

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    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/0972-2327.104343

    authors: Ghosh K,Chatterjee A,Sau JT,Dey S

    更新日期:2012-10-01 00:00:00

  • Refining the Clinical Features of Serotonin Syndrome: A Prospective Observational Study of 45 Patients.

    abstract:Introduction:Serotonin syndrome (SS) is a drug-induced clinical syndrome that results from the excess intrasynaptic concentration of serotonin. Prospective observations are limited for SS. Methods:We prospectively recruited 45 consecutive adult patients (>18 years) fulfilling the Hunter's criteria for SS. All patients...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/aian.AIAN_344_18

    authors: Prakash S,Rathore C,Rana KK,Dave A,Joshi H,Patel J

    更新日期:2019-01-01 00:00:00

  • A Preventable Ataxia: Cerebrotendinous Xanthomatosis.

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    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/aian.AIAN_126_18

    authors: Shaji B,Srikumar B,Ramachandran D

    更新日期:2019-10-01 00:00:00

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    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/0972-2327.164830

    authors: Langille MM,Desai J

    更新日期:2015-09-01 00:00:00

  • Prevalence and association of lifestyle factors with extracranial carotid atherosclerosis in non-cardioembolic anterior circulation strokes in adult males less than 50 years: One year cross-sectional study.

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    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/0972-2327.120448

    authors: Hassan KM,Verma A,Prakash S,Chandran V,Kumar S,Banerji A

    更新日期:2013-10-01 00:00:00

  • Report: Stem cell applications in neurological practice, an expert group consensus appraisal.

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    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/0972-2327.186825

    authors: Devi MG,Sharma A,Mohanty S,Jain N,Verma K,Padma MV,Pal P,Chabbra HS,Khadilkar S,Prabhakar S,Singh G

    更新日期:2016-07-01 00:00:00

  • Coexistence of central nucleus, cores, and rods: Diagnostic relevance.

    abstract:BACKGROUND:Congenital myopathies (CMs) though considered distinct disorders, simultaneous occurrence of central nucleus, nemaline rods, and cores in the same biopsy are scarcely reported. OBJECTIVE:A retrospective reassessment of cases diagnosed as CMs to look for multiple pathologies missed, if any, during the initia...

    journal_title:Annals of Indian Academy of Neurology

    pub_type: 杂志文章

    doi:10.4103/0972-2327.176861

    authors: Dhinakaran S,Kumar RS,Thakkar R,Narayanappa G

    更新日期:2016-04-01 00:00:00

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    abstract::Meningitis and meningoencephalitis account for the majority of central nervous system infections by Listeria monocytogenes (Lm). Macroscopic listerial brain abscess is a rare infection. Early recognition of Listeria brain abscesses represents a major diagnostic challenge. Mortality from Listeria brain abscesses is hig...

    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/aian.AIAN_233_18

    authors: Flores-Perez RO,Villarreal-Villarreal CD,Garza JAC,Galarza-Delgado DA

    更新日期:2020-01-01 00:00:00

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    abstract::Rhabdomyolysis and myoglobinuria are a rare complication of dermatomyositis. Such patient can land up in acute renal failure. Recognition of this fact has important therapeutic implications as patients require immunotherapy in addition to the symptomatic treatment for renal failure. We report a case of dermatomyositis...

    journal_title:Annals of Indian Academy of Neurology

    pub_type:

    doi:10.4103/0972-2327.48853

    authors: Joshi D,Kumar N,Rai A

    更新日期:2009-01-01 00:00:00