Efficient DNA-Polymer Coupling in Organic Solvents: A Survey of Amide Coupling, Thiol-Ene and Tetrazine-Norbornene Chemistries Applied to Conjugation of Poly(N-Isopropylacrylamide).

abstract：:Although most nanofabrication techniques can control nano/micro particle (NMP) size over a wide range, the majority of NMPs for biomedical applications exhibits a diameter of ~100 nm. Here, the vascular distribution of spherical particles, from 10 to 1,000 nm in diameter, is studied using intravital microscopy and com...

journal_title：Scientific reports

authors： Lee TR,Choi M,Kopacz AM,Yun SH,Liu WK,Decuzzi P

更新日期：2013-01-01 00:00:00

abstract：:Erythropoiesis is regulated by the erythropoietin receptor (EpoR) binding to its ligand. The transmembrane domain (TMD) and the juxtamembrane (JM) regions of the EpoR are important for signal transduction across the cell membrane. We report a solution NMR study of the mouse erythropoietin receptor (mEpoR) comprising t...

journal_title：Scientific reports

authors： Li Q,Wong YL,Yueqi Lee M,Li Y,Kang C

更新日期：2015-08-28 00:00:00

abstract：:Although diatoms have been extensively studied as bioreactors, only a limited number of efficient gene promoters are available. Therefore, the development of new endogenous promoters is important for the heterologous production of a variety of recombinant proteins. Herein, we identified the most abundant secreted prot...

journal_title：Scientific reports

authors： Erdene-Ochir E,Shin BK,Kwon B,Jung C,Pan CH

更新日期：2019-07-09 00:00:00

abstract：:Prospective observation of hemodynamic changes before and after the formation of atherosclerotic stenosis in the carotid artery is difficult. Thus, a vessel surface repairing method was used for retrospective hemodynamic study before and after atherosclerotic stenosis formation in carotid artery. The three-dimensional...

journal_title：Scientific reports

authors： Li X,Sun B,Zhao H,Ge X,Liang F,Li X,Xu J,Liu X

更新日期：2018-04-03 00:00:00

abstract：:Cartilage loss is a leading cause of disability among adults and effective therapy remains elusive. Neonatal chondrocytes (NChons) are an attractive allogeneic cell source for cartilage repair, but their clinical translation has been hindered by scarce donor availability. Here we examine the potential for catalyzing c...

journal_title：Scientific reports

authors： Lai JH,Kajiyama G,Smith RL,Maloney W,Yang F

更新日期：2013-12-19 00:00:00

abstract：:This study was to investigate effects of progesterone vaginal sustained-release gel and intramuscular injection of progesterone on frozen-thawed embryos transfer in 3013 patients receiving vaginal progesterone sustained-release gel and progesterone injection in artificial cycle for frozen-thawed embryo transfer. All p...

journal_title：Scientific reports

authors： Jiang L,Luo ZY,Hao GM,Gao BL

更新日期：2019-10-24 00:00:00

abstract：:From the 1950s, the Po delta, one of the largest anthropogenic world deltas, has been subjected to a fast degradation and shoreline retreat due a marked reduction of sediment supply, mainly controlled by human impacts/factors, including subsidence. Through the interpretation of satellite images, coupled with the analy...

journal_title：Scientific reports

authors： Ninfo A,Ciavola P,Billi P

更新日期：2018-02-22 00:00:00

abstract：:Mueller microscopes enable imaging of the optical anisotropic properties of biological or non-biological samples, in phase and amplitude, at sub-micrometre scale. However, the development of Mueller microscopes poses an instrumental challenge: the production of polarimetric parameters must be sufficiently quick to ens...

journal_title：Scientific reports

authors： Rivet S,Dubreuil M,Bradu A,Le Grand Y

更新日期：2019-03-08 00:00:00

abstract：:Although hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF), the mechanisms underlying liver fibrotic progression remain unclear. Here, we investigated the gene expression profiles of HBV-related LF patients. Whole genome expression arrays were used to detect gene expression in liver biopsy ...

journal_title：Scientific reports

authors： Wang M,Gong Q,Zhang J,Chen L,Zhang Z,Lu L,Yu D,Han Y,Zhang D,Chen P,Zhang X,Yuan Z,Huang J,Zhang X

更新日期：2017-03-06 00:00:00

abstract：:Mucus is responsible for controlling transport and barrier function in biological systems, and its properties can be significantly affected by compositional and environmental changes. In this study, the impacts of pH and CaCl2 were examined on the solution-to-gel transition of mucin, the primary structural component o...

journal_title：Scientific reports

authors： Curnutt A,Smith K,Darrow E,Walters KB

更新日期：2020-05-29 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep44640. ...

journal_title：Scientific reports

authors： Dong S,Wen P,Zhang Q,Li X,Tan K,Nieh J

更新日期：2017-06-30 00:00:00

abstract：:The double-slit experiment strikingly demonstrates the wave-particle duality of quantum objects. In this famous experiment, particles pass one-by-one through a pair of slits and are detected on a distant screen. A distinct wave-like pattern emerges after many discrete particle impacts as if each particle is passing th...

journal_title：Scientific reports

authors： Kolenderski P,Scarcella C,Johnsen KD,Hamel DR,Holloway C,Shalm LK,Tisa S,Tosi A,Resch KJ,Jennewein T

更新日期：2014-04-28 00:00:00

abstract：:In the present work, we demonstrated the biosynthesis of silver nanoparticles (AgNPs) by highly stable, economic and eco-friendly method using leaf extract of Terminalia arjuna (T. arjuna) and employing as a catalyst for the degradation of methyl orange (MO), methylene blue (MB), congo red (CR) and 4- nitrophenol (4-N...

journal_title：Scientific reports

authors： Raj S,Singh H,Trivedi R,Soni V

更新日期：2020-06-15 00:00:00

abstract：:The promising ability of a plasma wiggler based on laser wakefield acceleration to produce betatron X-rays with photon energies of a few keV to hundreds of keV and a peak brilliance of 10(22)-10(23) photons/s/mm(2)/mrad(2)/0.1%BW has been demonstrated, providing an alternative to large-scale synchrotron light sources....

journal_title：Scientific reports

authors： Ma Y,Chen L,Li D,Yan W,Huang K,Chen M,Sheng Z,Nakajima K,Tajima T,Zhang J

更新日期：2016-07-26 00:00:00

abstract：:While neurofilament light chain (NfL) measurement in serum is a well-established marker of neuroaxonal damage in multiple sclerosis (MS), data on astroglial markers in serum are missing. In our study, glial fibrillary acid protein (GFAP) and NfL were measured in cerebrospinal fluid (CSF) and serum of MS patients and p...

journal_title：Scientific reports

authors： Abdelhak A,Huss A,Kassubek J,Tumani H,Otto M

更新日期：2018-10-04 00:00:00

abstract：:Ultrasound-enhanced drug delivery has shown great promise in providing targeted burst release of drug at the site of the disease. Yet current solid ultrasound-responsive particles are non-degradable with limited potential for drug-loading. Here, we report on an ultrasound-responsive multi-cavity poly(lactic-co-glycoli...

journal_title：Scientific reports

authors： Su X,Thomas RG,Bharatula LD,Kwan JJ

更新日期：2019-07-03 00:00:00

abstract：:2-hydroxy-1,4 naphthoquinone (lawsone) is widely used and induces environmental pollutions during its production and application. In the present study, a lawsone-degrading bacterium strain, LH-3 was successfully isolated from the activated sludge. Based on the 16S rRNA gene analysis, the strain LH-3 phylogenetically b...

journal_title：Scientific reports

authors： Yang L,Cai T,Ding D,Cai T,Jiang C,Li H,Yang Q,Chen L

更新日期：2017-07-28 00:00:00

abstract：:Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-cancer molecular mech...

journal_title：Scientific reports

authors： Peng Z,Wang Y,Fan J,Lin X,Liu C,Xu Y,Ji W,Yan C,Su C

更新日期：2017-01-24 00:00:00

abstract：:The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptations during evolutio...

journal_title：Scientific reports

authors： Lopes-Marques M,Serrano C,Cardoso AR,Salazar R,Seixas S,Amorim A,Azevedo L,Prata MJ

更新日期：2020-07-14 00:00:00

abstract：:Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery. As human pluripotent stem cell-derived cardiomyocytes remain functionally fetal-type, close monitoring of electrophysiological maturation is critical for their furthe...

journal_title：Scientific reports

authors： Zhu H,Scharnhorst KS,Stieg AZ,Gimzewski JK,Minami I,Nakatsuji N,Nakano H,Nakano A

更新日期：2017-03-07 00:00:00

abstract：:The gist of natural scenes can be extracted very rapidly and even without focal attention. However, it is unclear whether and to what extent the gist of natural scenes can break through the bottleneck of crowding, a phenomenon in which object recognition will be immensely impaired. In the first two experiments, a targ...

journal_title：Scientific reports

authors： Gong M,Xuan Y,Smart LJ,Olzak LA

更新日期：2018-09-19 00:00:00

abstract：:The anhydrofructose pathway is an alternate pathway for glycogen degradation by α-1,4-glucan lyase. The sugar 1,5-anhydro-D-fructose (1,5-AF) acts as the central intermediate of this pathway, but its physiological role of in mammals is unclear. Glycation reactions forming advanced glycation end-products (AGEs) are imp...

journal_title：Scientific reports

authors： Sakasai-Sakai A,Takata T,Suzuki H,Maruyama I,Motomiya Y,Takeuchi M

更新日期：2019-07-15 00:00:00

abstract：:The physical properties of polycrystalline materials depend on their microstructure, which is the nano- to centimeter scale arrangement of phases and defects in their interior. Such microstructure depends on the shape, crystallographic phase and orientation, and interfacing of the grains constituting the material. Thi...

journal_title：Scientific reports

authors： Cereser A,Strobl M,Hall SA,Steuwer A,Kiyanagi R,Tremsin AS,Knudsen EB,Shinohara T,Willendrup PK,da Silva Fanta AB,Iyengar S,Larsen PM,Hanashima T,Moyoshi T,Kadletz PM,Krooß P,Niendorf T,Sales M,Schmahl WW,Schmidt S

更新日期：2017-08-25 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular processes are poorly described. This study aimed to examine lactate metabolism in cultured human...

journal_title：Scientific reports

authors： Lund J,Aas V,Tingstad RH,Van Hees A,Nikolić N

更新日期：2018-06-29 00:00:00

abstract：:Genetic factors affect host susceptibility to pathogens. In this population-based case control study, we explored the genetic polymorphisms of IL-17, TLR4 and miR-146a in association with pulmonary tuberculosis in a Chinese Han population. We recruited 1601 pulmonary tuberculosis patients matched with 1526 healthy con...

journal_title：Scientific reports

authors： Wang M,Xu G,Lü L,Xu K,Chen Y,Pan H,Burstrom B,Burstrom K,Wang J

更新日期：2016-06-24 00:00:00

abstract：:It has been suggested that orthographic transparency and age changes may affect the relationship between visual attention span (VAS) deficit and reading difficulty. The present study explored the developmental trend of VAS in children with developmental dyslexia (DD) in Chinese, a logographic language with a deep orth...

journal_title：Scientific reports

authors： Zhao J,Liu M,Liu H,Huang C

更新日期：2018-02-16 00:00:00

abstract：:The temporal structure of sound such as in music and speech increases the efficiency of auditory processing by providing listeners with a predictable context. Musical meter is a good example of a sound structure that is temporally organized in a hierarchical manner, with recent studies showing that meter optimizes neu...

journal_title：Scientific reports

authors： Moon IJ,Kang S,Boichenko N,Hong SH,Lee KM

更新日期：2020-09-29 00:00:00

abstract：:Nitric oxide (NO) regulates plant growth and development as well as responses to stress that enhanced its endogenous production. Arabidopsis plants exposed to a pulse of exogenous NO gas were used for untargeted global metabolomic analyses thus allowing the identification of metabolic processes affected by NO. At earl...

journal_title：Scientific reports

authors： León J,Costa Á,Castillo MC

更新日期：2016-11-25 00:00:00

abstract：:Processing the meaning of action language correlates with somatotopic activity in premotor cortex (PMC). A previous neurostimulation study supported a causal contribution of PMC activity to action verb understanding, but the direction of the effect was unexpected: inhibiting PMC made participants respond faster to act...

journal_title：Scientific reports

authors： Gijssels T,Ivry RB,Casasanto D

更新日期：2018-07-30 00:00:00