A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death.

Abstract:

BACKGROUND:The prevalence of Brugada ECG pattern (BrEP) is different in different regions, and its mean prevalence over the world is unknown. The risk of people with BrEP for death remains unknown. We performed a meta-analysis to determine the prevalence of BrEP and risk ratio (RR) for death. METHODS:Relevant studies published between July 1, 2000 and August 20, 2016, which contain prevalence and RR for all-cause death and cardiac death, were included. The prevalence and RR are analyzed using meta-analysis. RESULTS:We finally retrieved 24 studies of the prevalence for BrEP and 5 studies of the RR for all-cause death and cardiac death. The worldwide mean prevalence of BrEP is 0.4%, with highest in Asia (0.9%) and lowest in North America (0.2%). Additionally, the mean prevalence in male is 0.9%, whereas it is 0.1% in female. The RR of BrEP for all-cause death is 0.78 (95% confidence interval 0.45-1.37), and for cardiac death it is 0.92 (95% confidence interval 0.23-3.66). CONCLUSION:The prevalence of BrEP is about 0.4% around the world with different prevalence in region and sex. Our study shows that BrEP may not be taken as a predictor of all-cause death and cardiac death.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Quan XQ,Li S,Liu R,Zheng K,Wu XF,Tang Q

doi

10.1097/MD.0000000000005643

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

e5643

issue

50

eissn

0025-7974

issn

1536-5964

pii

00005792-201612160-00042

journal_volume

95

pub_type

杂志文章,meta分析

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