Rhabdomyosarcoma.

Abstract:

:A malignant tumor of striated muscle origin, rhabdomyosarcoma (RMS) is a childhood tumor that has benefited from nearly 30 years of multimodality therapy, culminating in a >70% overall 5-year survival. Prognosis for RMS is dependent on primary tumor site, age, completeness of resection, presence and number of metastatic sites, histology, and biology of the tumor cells. Multimodality treatment is based on risk stratification according to pre-treatment stage, postoperative group, histology, and site. Unique to RMS is the concept of postoperative clinical grouping that assesses the completeness of disease resection and takes into account lymph node evaluation at both the regional and metastatic basins. At all sites, if complete operative resection of disease is accomplished, including microscopic disease, survival is improved. Therefore, the surgeon plays a vital role in determining risk stratification for treatment, local control of the primary tumor and overall outcome for the patient with RMS.

journal_name

Semin Pediatr Surg

authors

Dasgupta R,Fuchs J,Rodeberg D

doi

10.1053/j.sempedsurg.2016.09.011

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

276-283

issue

5

eissn

1055-8586

issn

1532-9453

pii

S1055-8586(16)30049-X

journal_volume

25

pub_type

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