Pluripotent stem cells: the last 10 years.

Abstract:

:Pluripotent stem cells (PSCs) can differentiate into virtually any cell type in the body, making them attractive for both regenerative medicine and drug discovery. Over the past 10 years, technological advances and innovative platforms have yielded first-in-man PSC-based clinical trials and opened up new approaches for disease modeling and drug development. Induced PSCs have become the foremost alternative to embryonic stem cells and accelerated the development of disease-in-a-dish models. Over the years and with each new discovery, PSCs have proven to be extremely versatile. This review article highlights key advancements in PSC research, from 2006 to 2016, and how they will guide the direction of the field over the next decade.

journal_name

Regen Med

journal_title

Regenerative medicine

authors

Kimbrel EA,Lanza R

doi

10.2217/rme-2016-0117

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

831-847

issue

8

eissn

1746-0751

issn

1746-076X

journal_volume

11

pub_type

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