Tuning charge and correlation effects for a single molecule on a graphene device.

abstract：:Choroidal neovascularization (CNV) is the major cause of vision loss in wet age-related macular degeneration (AMD). Current therapies require repeated intravitreal injections, which are painful and can cause infection, bleeding, and retinal detachment. Here we develop nanoparticles (NP-[CPP]) that can be administered ...

journal_title：Nature communications

authors： Wang Y,Liu CH,Ji T,Mehta M,Wang W,Marino E,Chen J,Kohane DS

更新日期：2019-02-18 00:00:00

abstract：:Despite extensive studies on transcription mechanisms, it is unknown how termination complexes are disassembled, especially in what order the essential components dissociate. Our single-molecule fluorescence study unveils that RNA transcript release precedes RNA polymerase (RNAP) dissociation from the DNA template muc...

journal_title：Nature communications

authors： Kang W,Ha KS,Uhm H,Park K,Lee JY,Hohng S,Kang C

更新日期：2020-01-23 00:00:00

abstract：:Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We report that suppleme...

journal_title：Nature communications

authors： Tan HWS,Sim AYL,Long YC

更新日期：2017-08-24 00:00:00

abstract：:The main advantage of organic transistors with dual gates/bases is that the threshold voltages can be set as a function of the applied second gate/base bias, which is crucial for the application in logic gates and integrated circuits. However, incorporating a dual gate/base structure into an ultra-short channel vertic...

journal_title：Nature communications

authors： Guo E,Wu Z,Darbandy G,Xing S,Wang SJ,Tahn A,Göbel M,Kloes A,Leo K,Kleemann H

更新日期：2020-09-18 00:00:00

abstract：:In recent years, there has been marked increase in research aimed to introduce alkali vapours into guided-wave configurations. Owing to the significant reduction in device dimensions, the increase in density of states, the interaction with surfaces and primarily the high intensities carried along the structure, a plet...

journal_title：Nature communications

authors： Stern L,Desiatov B,Mazurski N,Levy U

更新日期：2017-02-09 00:00:00

abstract：:Many porous materials are damaged by pressure exerted by salt crystals growing in their pores. This is a serious issue in conservation science, geomorphology, geotechnical engineering and concrete materials science. In all cases, a central question is whether crystallization pressure will cause damage. Here we present...

journal_title：Nature communications

authors： Flatt RJ,Caruso F,Sanchez AM,Scherer GW

更新日期：2014-09-11 00:00:00

abstract：:Epitaxy is widely employed to create highly oriented crystalline films. A less appreciated, but nonetheless powerful means of creating such films is via topotactic transformation, in which a chemical reaction transforms a single crystal of one phase into a single crystal of a different phase, which inherits its orient...

journal_title：Nature communications

authors： Mairoser T,Mundy JA,Melville A,Hodash D,Cueva P,Held R,Glavic A,Schubert J,Muller DA,Schlom DG,Schmehl A

更新日期：2015-07-16 00:00:00

abstract：:EpCAM (epithelial cell adhesion molecule), a stem and carcinoma cell marker, is a cell surface protein involved in homotypic cell-cell adhesion via intercellular oligomerization and proliferative signalling via proteolytic cleavage. Despite its use as a diagnostic marker and being a drug target, structural details of ...

journal_title：Nature communications

authors： Pavšič M,Gunčar G,Djinović-Carugo K,Lenarčič B

更新日期：2014-08-28 00:00:00

abstract：:Centromeres are specified epigenetically through the deposition of the centromere-specific histone H3 variant CENP-A. However, how additional epigenetic features are involved in centromere specification is unknown. Here, we find that histone H4 Lys5 and Lys12 acetylation (H4K5ac and H4K12ac) primarily occur within the...

journal_title：Nature communications

authors： Shang WH,Hori T,Westhorpe FG,Godek KM,Toyoda A,Misu S,Monma N,Ikeo K,Carroll CW,Takami Y,Fujiyama A,Kimura H,Straight AF,Fukagawa T

更新日期：2016-11-04 00:00:00

abstract：:Quantum metrology bears a great promise in enhancing measurement precision, but is unlikely to become practical in the near future. Its concepts can nevertheless inspire classical or hybrid methods of immediate value. Here we demonstrate NOON-like photonic states of m quanta of angular momentum up to m=100, in a setup...

journal_title：Nature communications

authors： D'Ambrosio V,Spagnolo N,Del Re L,Slussarenko S,Li Y,Kwek LC,Marrucci L,Walborn SP,Aolita L,Sciarrino F

更新日期：2013-01-01 00:00:00

abstract：:Highly specific Cas9 nucleases derived from SpCas9 are valuable tools for genome editing, but their wide applications are hampered by a lack of knowledge governing guide RNA (gRNA) activity. Here, we perform a genome-scale screen to measure gRNA activity for two highly specific SpCas9 variants (eSpCas9(1.1) and SpCas9...

journal_title：Nature communications

authors： Wang D,Zhang C,Wang B,Li B,Wang Q,Liu D,Wang H,Zhou Y,Shi L,Lan F,Wang Y

更新日期：2019-09-19 00:00:00

abstract：:When assembling individual quantum components into a mesoscopic circuit, the interplay between Coulomb interaction and charge granularity breaks down the classical laws of electrical impedance composition. Here we explore experimentally the thermal consequences, and observe an additional quantum mechanism of electroni...

journal_title：Nature communications

authors： Sivre E,Duprez H,Anthore A,Aassime A,Parmentier FD,Cavanna A,Ouerghi A,Gennser U,Pierre F

更新日期：2019-12-10 00:00:00

abstract：:Manganese based layered oxides have received increasing attention as cathode materials for sodium ion batteries due to their high theoretical capacities and good sodium ion conductivities. However, the Jahn-Teller distortion arising from the manganese (III) centers destabilizes the host structure and deteriorates the ...

journal_title：Nature communications

authors： Zhang K,Kim D,Hu Z,Park M,Noh G,Yang Y,Zhang J,Lau VW,Chou SL,Cho M,Choi SY,Kang YM

更新日期：2019-01-07 00:00:00

abstract：:In nature, plant tendrils can produce two fundamental motion modes, bending and chiral twisting (helical curling) distortions, under the stimuli of sunlight, humidity, wetting or other atmospheric conditions. To date, many artificial plant-like mechanical machines have been developed. Although some previously reported...

journal_title：Nature communications

authors： Wang M,Lin BP,Yang H

更新日期：2016-12-22 00:00:00

abstract：:The outcome of molecule-surface collisions can be modified by pre-aligning the molecule; however, experiments accomplishing this are rare because of the difficulty of preparing molecules in aligned quantum states. Here we present a general solution to this problem based on magnetic manipulation of the rotational magne...

journal_title：Nature communications

authors： Godsi O,Corem G,Alkoby Y,Cantin JT,Krems RV,Somers MF,Meyer J,Kroes GJ,Maniv T,Alexandrowicz G

更新日期：2017-05-08 00:00:00

abstract：:The original HTML version of this Article had an incorrect Published online date of 20 March 2019; it should have been 18 March 2019. This has been corrected in the HTML version of the Article. The PDF version was correct from the time of publication. ...

journal_title：Nature communications

authors： Hu Z,Wessels HJCT,van Alen T,Jetten MSM,Kartal B

更新日期：2019-04-18 00:00:00

abstract：:Hypertensive disorders in pregnancy (HDPs) are leading perinatal diseases. Using a national cohort of 2,043,182 pregnant women in China, we evaluated the association between ambient temperatures and HDP subgroups, including preeclampsia or eclampsia, gestational hypertension, and superimposed preeclampsia. Under extre...

journal_title：Nature communications

authors： Xiong T,Chen P,Mu Y,Li X,Di B,Li J,Qu Y,Tang J,Liang J,Mu D

更新日期：2020-06-10 00:00:00

abstract：:The leaf economics spectrum (LES) describes consistent correlations among a variety of leaf traits that reflect a gradient from conservative to acquisitive plant strategies. So far, whether the LES holds in wetland plants at a global scale has been unclear. Using data on 365 wetland species from 151 studies, we find t...

journal_title：Nature communications

authors： Pan Y,Cieraad E,Armstrong J,Armstrong W,Clarkson BR,Colmer TD,Pedersen O,Visser EJW,Voesenek LACJ,van Bodegom PM

更新日期：2020-09-09 00:00:00

abstract：:This corrects the article DOI: 10.1038/ncomms6053. ...

journal_title：Nature communications

authors： Comte L,Murienne J,Grenouillet G

更新日期：2018-04-10 00:00:00

abstract：:Ultrafast photoinduced electron transfer preceding energy equilibration still poses many experimental and conceptual challenges to the optimization of photoconversion since an atomic-scale description has so far been beyond reach. Here we combine femtosecond transient optical absorption spectroscopy with ultrafast X-r...

journal_title：Nature communications

authors： Canton SE,Kjær KS,Vankó G,van Driel TB,Adachi S,Bordage A,Bressler C,Chabera P,Christensen M,Dohn AO,Galler A,Gawelda W,Gosztola D,Haldrup K,Harlang T,Liu Y,Møller KB,Németh Z,Nozawa S,Pápai M,Sato T,Sato T,Su

更新日期：2015-03-02 00:00:00

abstract：:Deregulation of mitochondrial network in terminally differentiated cells contributes to a broad spectrum of disorders. Methylmalonic acidemia (MMA) is one of the most common inherited metabolic disorders, due to deficiency of the mitochondrial methylmalonyl-coenzyme A mutase (MMUT). How MMUT deficiency triggers cell d...

journal_title：Nature communications

authors： Luciani A,Schumann A,Berquez M,Chen Z,Nieri D,Failli M,Debaix H,Festa BP,Tokonami N,Raimondi A,Cremonesi A,Carrella D,Forny P,Kölker S,Diomedi Camassei F,Diaz F,Moraes CT,Di Bernardo D,Baumgartner MR,Devuyst O

更新日期：2020-02-20 00:00:00

abstract：:A diversity of self-propelled chemical motors, based on Marangoni propulsive forces, has been developed in recent years. However, most motors are non-functional due to poor performance, a lack of control, and the use of toxic materials. To overcome these limitations, we have developed multifunctional and biodegradable...

journal_title：Nature communications

authors： Pena-Francesch A,Giltinan J,Sitti M

更新日期：2019-07-18 00:00:00

abstract：:Contextual influences on choice are ubiquitous in ecological settings. Current evidence suggests that subjective values are normalized with respect to the distribution of potentially available rewards. However, how this context-sensitivity is realised in the brain remains unknown. To address this, here we examine func...

journal_title：Nature communications

authors： Rigoli F,Friston KJ,Dolan RJ

更新日期：2016-08-18 00:00:00

abstract：:Biologists have long been fascinated by the amazing diversity of animal colour patterns. Despite much interest, the underlying evolutionary and developmental mechanisms contributing to their rich variety remain largely unknown, especially the vivid and complex colour patterns seen in vertebrates. Here, we show that co...

journal_title：Nature communications

authors： Miyazawa S,Okamoto M,Kondo S

更新日期：2010-09-07 00:00:00

abstract：:Glycans from microbial pathogens are well known pathogen-associated molecular patterns that are recognized by the host immunity; however, little is known about whether and how mammalian self-glycans activate the host immune response, especially in the context of autoimmune disease. Using biochemical fractionation and ...

journal_title：Nature communications

authors： Fermaintt CS,Sano K,Liu Z,Ishii N,Seino J,Dobbs N,Suzuki T,Fu YX,Lehrman MA,Matsuo I,Yan N

更新日期：2019-05-30 00:00:00

abstract：:Scenarios that limit global warming to below 2 °C by 2100 assume significant land-use change to support large-scale carbon dioxide (CO2) removal from the atmosphere by afforestation/reforestation, avoided deforestation, and Biomass Energy with Carbon Capture and Storage (BECCS). The more ambitious mitigation scenarios...

journal_title：Nature communications

authors： Harper AB,Powell T,Cox PM,House J,Huntingford C,Lenton TM,Sitch S,Burke E,Chadburn SE,Collins WJ,Comyn-Platt E,Daioglou V,Doelman JC,Hayman G,Robertson E,van Vuuren D,Wiltshire A,Webber CP,Bastos A,Boysen L,Ciais

更新日期：2018-08-07 00:00:00

abstract：:Acoustic communication is enabled by the evolution of specialised hearing and sound producing organs. In this study, we performed a large-scale macroevolutionary study to understand how both hearing and sound production evolved and affected diversification in the insect order Orthoptera, which includes many familiar s...

journal_title：Nature communications

authors： Song H,Béthoux O,Shin S,Donath A,Letsch H,Liu S,McKenna DD,Meng G,Misof B,Podsiadlowski L,Zhou X,Wipfler B,Simon S

更新日期：2020-10-02 00:00:00

abstract：:Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life history tradeoffs. Many species of Colias butterflies exhibit an alternative life history str...

journal_title：Nature communications

authors： Woronik A,Tunström K,Perry MW,Neethiraj R,Stefanescu C,Celorio-Mancera MP,Brattström O,Hill J,Lehmann P,Käkelä R,Wheat CW

更新日期：2019-12-17 00:00:00

abstract：:Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite burden in Plasmodium falciparum infections, and antimalarial control is highly dependent on ART combination therapies (ACTs). Decreased sensitivity to ARTs is emerging, making it critically important to understand the mechan...

journal_title：Nature communications

authors： Bridgford JL,Xie SC,Cobbold SA,Pasaje CFA,Herrmann S,Yang T,Gillett DL,Dick LR,Ralph SA,Dogovski C,Spillman NJ,Tilley L

更新日期：2018-09-18 00:00:00

abstract：:Various viruses enter host cells via endocytosis, but the molecular mechanisms underlying the specific internalization pathways remain unclear. Here we show that influenza A viruses (IAVs) enter cells via redundant pathways of clathrin-mediated and clathrin-independent endocytosis, with intracellular Ca(2+) having a c...

journal_title：Nature communications

authors： Fujioka Y,Tsuda M,Nanbo A,Hattori T,Sasaki J,Sasaki T,Miyazaki T,Ohba Y

更新日期：2013-01-01 00:00:00