Capsular polysaccharide production and serum survival of Vibrio vulnificus are dependent on antitermination control by RfaH.

Abstract:

:The human pathogen Vibrio vulnificus undergoes phase variation among colonial morphotypes, including a virulent opaque form which produces capsular polysaccharide (CPS) and a translucent phenotype that produces little or no CPS and is attenuated. Here, we found that a V. vulnificus mutant defective for RfaH antitermination control showed a diminished capacity to undergo phase variation and displayed significantly reduced distal gene expression within the Group I CPS operon. Moreover, the rfaH mutant produced negligible CPS and was highly sensitive to killing by normal human serum, results which indicate that RfaH is likely essential for virulence in this bacterium.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

Garrett SB,Garrison-Schilling KL,Cooke JT,Pettis GS

doi

10.1002/1873-3468.12490

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

4564-4572

issue

24

eissn

0014-5793

issn

1873-3468

journal_volume

590

pub_type

信件
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    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/s0014-5793(03)00596-9

    authors: Murakami M,Das S,Kim YJ,Cho W,Kudo I

    更新日期:2003-07-10 00:00:00

  • Hydrocortisone inhibits prostaglandin production but not arachidonic acid release from cultured macrophages.

    abstract::We have investigated the action of hydrocortisosone on arachidonic acid mobilisation in cultures of mouse peritoneal macrophages, mouse L929 cells and the mouse macrophage-like cell line RAW264. Hydrocortisone inhibits both arachidonic acid release and prostaglandin production by L929 cells. However, prostaglandin pro...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(84)81093-5

    authors: Wood JN,Coote PR,Rhodes J

    更新日期:1984-08-20 00:00:00

  • Class I and IVa beta-tubulin isotypes expressed in adult mouse brain are glutamylated.

    abstract::Several types of post-translational modifications contribute to the high level of tubulin heterogeneity in the brain. An important modification is glutamylation of the major brain-specific isotypes, such as class Ia/b of alpha-tubulin and classes II and III of beta-tubulin. Here we describe experiments to determine if...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(94)01018-8

    authors: Mary J,Redeker V,Le Caer JP,Promé JC,Rossier J

    更新日期:1994-10-10 00:00:00

  • Fatty acid acylation of membrane skeletal proteins in human erythrocytes.

    abstract::Fatty acid acylation of membrane proteins was studied on human erythrocytes by measuring incorporation of [3H]palmitate at different specific radioactivities. A 55 kDa polypeptide within the band 4.5 region was the main acceptor protein for acylation by fatty acids (palmitate, stearate, oleate), while other polypeptid...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(90)80033-f

    authors: Maretzki D,Mariani M,Lutz HU

    更新日期:1990-01-01 00:00:00

  • Site-specific mutagenesis of the reaction centre from Rhodobacter sphaeroides studied by Fourier transform Raman spectroscopy: mutations at tyrosine M210 do not affect the electronic structure of the primary donor.

    abstract::The effects of mutation of residue tyrosine M210 on the primary donor bacteriochlorophylls have been investigated by near infrared FT-Raman spectroscopy in reaction centres purified from an antenna-deficient strain of Rhodobacter sphaeroides. We find that mutation at the M210 position does not significantly perturb th...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(94)80376-5

    authors: Jones MR,Heer-Dawson M,Mattioli TA,Hunter CN,Robert B

    更新日期:1994-02-14 00:00:00

  • Structures of the tumor necrosis factor alpha inducing protein Tipalpha: a novel virulence factor from Helicobacter pylori.

    abstract::Helicobacter pylori secretes a unique virulence factor, Tipalpha, that enters gastric cells and both stimulates the production of the TNF-alpha and activates the NF-kappaB pathway. The structures of a truncated version of Tipalpha (TipalphaN34) in two crystal forms are presented here. Tipalpha adopts a novel beta(1)al...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/j.febslet.2009.04.033

    authors: Tosi T,Cioci G,Jouravleva K,Dian C,Terradot L

    更新日期:2009-05-19 00:00:00

  • Evolution of the gene families forming the Pax/Six regulatory network: isolation of genes from primitive animals and molecular phylogenetic analyses.

    abstract::Some members of the Pax (paired box) and Six (sine oculis homeobox) gene families function as components of a gene regulatory network controlling eye development. To investigate the early evolution of the genetic interaction between Pax and Six genes, we identified and sequenced members of the Pax and Six gene familie...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/j.febslet.2007.03.027

    authors: Hoshiyama D,Iwabe N,Miyata T

    更新日期:2007-04-17 00:00:00

  • Isolation of a brain peptide identical to the intestinal PHI (peptide HI).

    abstract::The isolation of a brain peptide identical to the intestinal peptide PHI (peptide HI) is described. The peptide was isolated from porcine brain extract using a chemical assay method based on its C-terminal isoleucine amide structure. The complete amino acid sequence of the peptide was found to be: His-Ala-Asp-Gly-Val-...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(83)80617-6

    authors: Tatemoto K,Carlquist M,McDonald TJ,Mutt V

    更新日期:1983-03-21 00:00:00

  • Low resolution solution structure of the Bacillus subtilis glucose permease IIA domain derived from heteronuclear three-dimensional NMR spectroscopy.

    abstract::A low resolution solution structure of the IIA domain of the Bacillus subtilis phosphoenolpyruvate-sugar phosphotransferase system (PTS) glucose permease has been determined using 945 inter-residue and 724 intra-residue distance constraints derived from three-dimensional 15N and 13C edited NOESY spectra. A total of 15...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(92)80367-p

    authors: Fairbrother WJ,Gippert GP,Reizer J,Saier MH Jr,Wright PE

    更新日期:1992-01-20 00:00:00

  • Distinct distal and proximal p53-binding sites in the MCK promoter govern the transcriptional response to p53.

    abstract::We have investigated the functional importance of nucleotide sequence differences between proximal (P-) and distal (D-) p53-binding elements in the MCK promoter. P- and D-elements normally co-operate to permit synergistic promoter activation by p53. Interestingly, we find that P-elements cannot co-operate with each ot...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/s0014-5793(97)00283-4

    authors: Jackson P,Yardley G

    更新日期:1997-04-14 00:00:00

  • Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase.

    abstract::A complete cDNA clone encoding human cholesterol 7 alpha-hydroxylase has been isolated using a rat P-450ch7 alpha cDNA insert [(1989) FEBS Lett. 257, 97-100] as a probe and totally sequenced. The cDNA contained 1512-base pair open reading frame encoding 504 amino acid residues (Mr 57,630), 39-base pair 5'-untranslated...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(90)80992-r

    authors: Noshiro M,Okuda K

    更新日期:1990-07-30 00:00:00

  • Aluminum inhibits proteolytic degradation of amyloid beta peptide by cathepsin D: a potential link between aluminum accumulation and neuritic plaque deposition.

    abstract::Neuritic plaques are the key pathological feature of Alzheimer's disease, and amyloid beta (Abeta) peptides are major component of these plaques. In this study, we demonstrated the influence of aluminum (Al) on the Abeta peptide degradation by cathepsin D. Al did not directly affect the cathepsin D activity using smal...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/j.febslet.2006.10.075

    authors: Sakamoto T,Saito H,Ishii K,Takahashi H,Tanabe S,Ogasawara Y

    更新日期:2006-12-11 00:00:00

  • Tumor promoter 12-O-tetradecanoylphorbol 13-acetate inhibits mas/angiotensin receptor-stimulated inositol phosphate production and intracellular Ca2+ elevation in the 401L-C3 neuronal cell line.

    abstract::Stimulation of mas-oncogene transfected 401L-C3 cells by angiotensins leads to the production of inositol phosphates. This response shows dose dependence, and has an apparent rank order of potency angiotensin III greater than or equal to angiotensin II much greater than angiotensin I. Preincubation with 12-O-tetradeca...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(89)81422-x

    authors: Jackson TR,Hanley MR

    更新日期:1989-07-17 00:00:00

  • The geometries of interacting arginine-carboxyls in proteins.

    abstract::The geometries are reported for interacting arginine-carboxyl pairs obtained from 37 high resolution protein structures solved to a resolution of 2.0 A or better. The closest interatomic distance between the guanidinium and carboxyl is less than 4.2 A for 74 arginine and carboxyl groups, with the majority of these lyi...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(87)80441-6

    authors: Singh J,Thornton JM,Snarey M,Campbell SF

    更新日期:1987-11-16 00:00:00

  • Specific binding sites for 3,3'-diiodo-L-thyronine (3,3'-T2) in rat liver mitochondria.

    abstract::Specific binding sites for 3,3'-T2 can be detected in swollen and osmotically treated mitochondria (OTM) from normal and hypothyroid rat liver. In hypothyroid animals, maximal values of binding were obtained at 0 degrees C while values were lower at 37 degrees C and no specific binding could be observed at 60 degrees ...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(94)00840-x

    authors: Lanni A,Moreno M,Horst C,Lombardi A,Goglia F

    更新日期:1994-09-05 00:00:00

  • Chromatin-bound and free RNA polymerase A activities in rat thymus cells following glucocorticoid treatment.

    abstract::Treatment of rat thymus cell suspensions with dexamethasone resulted in inhibition of engaged RNA polymerase A, without significant change in free pool activity. Studies with the re-initiation inhibitor, rifamycin AF/0-13, and measurements of numbers of RNA polymerase A molecules and of elongation rates showed that th...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(84)81031-5

    authors: Dembinski TC

    更新日期:1984-07-23 00:00:00

  • Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex.

    abstract::The purinergic receptor P2X(7) is part of a complex signaling mechanism participating in a variety of physiological and pathological processes. Depending on the activation scheme, P2X(7) receptors in vivo are non-selective cation channels or form large pores that can mediate apoptotic cell death. Expression of P2X(7)R...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/j.febslet.2006.12.056

    authors: Locovei S,Scemes E,Qiu F,Spray DC,Dahl G

    更新日期:2007-02-06 00:00:00

  • A large conductance ion channel in the nuclear envelope of a higher plant cell.

    abstract::To detect and characterize ion channel activity in the nuclear envelope of a higher plant cell, we performed patch clamp experiments on nuclei isolated from coconut endosperm cells and on giant liposomes containing nuclear envelope fragments prepared from the same cells. An ion channel exhibiting a number of conductan...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(92)80290-w

    authors: Matzke AJ,Behensky C,Weiger T,Matzke MA

    更新日期:1992-05-04 00:00:00

  • Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition.

    abstract::Neoplastic cells metabolize higher amounts of glucose relative to normal cells in order to cover increased energetic and anabolic needs. Inhibition of the glycolytic enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) diminishes cancer cell proliferation and tumour growth in animals. In this work, w...

    journal_title:FEBS letters

    pub_type: 信件

    doi:10.1002/1873-3468.12338

    authors: Simon-Molas H,Calvo-Vidal MN,Castaño E,Rodríguez-García A,Navarro-Sabaté À,Bartrons R,Manzano A

    更新日期:2016-09-01 00:00:00

  • Decrease of cellular ATP by dihexanoylglycerol may limit responses to protein kinase C activation.

    abstract::1,2-sn-Dihexanoylglycerol (HHG) reduced the ATP content of HL-60 cells. This concentration-related (10-100 microM) effect reached a maximum of over 90%, was enantiomerically specific and not accompanied by release of lactate dehydrogenase. Oleoylacetylglycerols (3-100 microM) had no effect on ATP levels while phorbol ...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(87)80036-4

    authors: Dawson J,Thompson NT,Bonser RW,Hodson HF,Garland LG

    更新日期:1987-04-06 00:00:00

  • High activity of inclusion bodies formed in Escherichia coli overproducing Clostridium thermocellum endoglucanase D.

    abstract::The formation of cytoplasmic inclusion bodies by Escherichia coli overproducing Clostridium thermocellum endoglucanase D (EGD) was investigated. EGD was found in inclusion bodies as a 68 kDa form, whereas the size of the cytoplasmic form was 65 kDa. Upon solubilization with urea followed by dialysis, the 68 kDa form w...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(91)80478-l

    authors: Tokatlidis K,Dhurjati P,Millet J,Béguin P,Aubert JP

    更新日期:1991-04-22 00:00:00

  • PCR amplification of CGRP II mRNA. Variable expression in tumoral and non-tumoral human thyroid.

    abstract::Two genes code for calcitonin gene-related peptides (CGRPs). One expresses by tissue-specific alternate splicing calcitonin and CGRP I mRNAs, the other CGRP II mRNA. Calcitonin is the marker of sporadic or hereditary human medullary thyroid carcinoma (MTC). CGRP II expression is not well established in normal or tumor...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(90)80856-e

    authors: Lasmoles F,Minvielle S,Cohen R,Guliana JM,Delehaye MC,Segond N,Calmettes C,Milhaud G,Moukhtar MS

    更新日期:1990-12-17 00:00:00

  • Fluorescence-detected interactions of oligonucleotides in RecA complexes.

    abstract::A technique has been developed to probe directly RecA-DNA interactions by the use of the fluorescent chromophore, (+)anti-benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE), covalently attached to DNA. The 24-mer oligonucleotide 5'-d(CTACTAAACATGTACAAATCATCC) was specifically modified on the exocyclic nitrogen of the ...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(95)00600-e

    authors: Wittung P,Funk M,Jernström B,Nordén B,Takahashi M

    更新日期:1995-07-10 00:00:00

  • Footprinting of DNA secondary structure by high-intensity (laser) ultraviolet irradiation.

    abstract::The action of high-intensity ultraviolet pulse laser radiation on a 161 bp fragment of pBR 322 DNA (EcoRI-MspI fragment) was studied. At doses up to 5 X 10(18) photons/cm2 the N-glycosidic bond splitting is negligible. The action of hot piperidine on irradiated DNA leads to chain splitting at the residues, modified vi...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(85)80894-2

    authors: Budowsky EI,Kovalsky OI,Yakovlev DYu,Simukova NA,Rubin LB

    更新日期:1985-08-19 00:00:00

  • Phosphoramidon inhibits the generation of endothelin-1 from exogenously applied big endothelin-1 in cultured vascular endothelial cells and smooth muscle cells.

    abstract::When cultured porcine aortic endothelial cells (ECs) were incubated with porcine big endothelin-1 (bit ET-1(1-39)), there was a time-dependent increase in immunoreactive (IR)-ET in the culture supernatant, in addition to an endogenous IR-ET release fron the cells. Reverse-phase HPLC of the culture supernatant revealed...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(91)81149-3

    authors: Ikegawa R,Matsumura Y,Tsukahara Y,Takaoka M,Morimoto S

    更新日期:1991-11-18 00:00:00

  • Suppressors of RNA silencing encoded by plant viruses and their role in viral infections.

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    journal_title:FEBS letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.febslet.2005.08.041

    authors: Qu F,Morris TJ

    更新日期:2005-10-31 00:00:00

  • Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney.

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    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/s0014-5793(98)01328-3

    authors: Uwai Y,Okuda M,Takami K,Hashimoto Y,Inui K

    更新日期:1998-11-06 00:00:00

  • Proline isomerization during refolding of ribonuclease A is accelerated by the presence of folding intermediates.

    abstract::The trans----cis isomerization of Pro 93 was measured during refolding of bovine ribonuclease A. This isomerization is slow (tau = 500 s) under marginally stable folding conditions of 2.0 M GdmCl, pH 6, at 10 degrees C. However, it is strongly accelerated (tau = 100 s) in samples which, prior to isomerization, had bee...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(86)80408-2

    authors: Schmid FX

    更新日期:1986-03-31 00:00:00

  • Cell death induced by Pteris semipinnata L. is associated with p53 and oxidant stress in gastric cancer cells.

    abstract::In this study, we demonstrated that Ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F) had stronger cytotoxicity against MKN-45, a gastric cancer cell line bearing wild-type p53 than MKN-28, another gastric cancer cell line containing missense mutation in p53. The rapid increase of ROS level was involved in the me...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/j.febslet.2005.01.050

    authors: Liu Z,Ng EK,Liang NC,Deng YF,Leung BC,Chen GG

    更新日期:2005-02-28 00:00:00

  • The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina.

    abstract::Thymidine kinase in chick embryo retina reaches its highest values on the 8-10th day of development, then declines reaching the lowest value at hatching. The rate of DNA synthesis essentially follows this activity while, in contrast, nucleoside phosphotransferase increases progressively during development. Glucocortic...

    journal_title:FEBS letters

    pub_type: 杂志文章

    doi:10.1016/0014-5793(83)80042-8

    authors: Tesoriere G,Tesoriere L,Giuliano M,Vento R

    更新日期:1983-11-28 00:00:00