Genome analysis revealed novel genotypes and recombination of the human parechoviruses prevalent in children in Eastern China.

Abstract:

BACKGROUND:Human parechovirus (HPeV) is a genus of virus in the family Picornaviridae, having two species A and B. HPeVs are common infectious agents, usually causing mild diarrhea and respiratory disease in young children. RESULTS:Here, we collected and sequenced the near complete genome sequences of 17 novel HPeVs from children with diarrhea in eastern China, which showed significant nucleotide sequence divergence. Phylogenetic analysis based on the complete genomes of these HPeV strains revealed that they belonged to seven different genotypes (including three putative novel genotypes), suggesting that HPeVs showed genotype diversity in this area. Recombination analysis indicated that one of the HPeVs, belonging to HPeV-1 with strain name 146Chzj02, was a recombinant generated by inter-genotype recombination among three HPeV strains belonging to three different genotypes, respectively. CONCLUSION:Our data revealed the property of the genotype diversity of HPeVs prevalent in children with diarrhea in eastern China, which will be helpful in the future study of the viral evolution of HPeVs and the identification and typing of HPeVs in the clinical laboratory.

journal_name

Gut Pathog

journal_title

Gut pathogens

authors

Zhao X,Shi Y,Xia Y

doi

10.1186/s13099-016-0135-z

subject

Has Abstract

pub_date

2016-11-08 00:00:00

pages

52

issn

1757-4749

pii

135

journal_volume

8

pub_type

  • Existence of a novel qepA variant in quinolone resistant Escherichia coli from aquatic habitats of Bangladesh.

    abstract::Of 19 environmental Escherichia coli (n = 12) and Klebsiella pneumoniae (n = 7) tested for quinolone resistance-related genes qnrA, qnrB, qnrC, qnrS and qepA, four each of E. coli and K. pneumoniae possessed qnrS, and another E. coli isolate possessed a new variant of qepA. This is the first detection of qepA in envir...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0207-8

    authors: Rahman Z,Islam A,Rashid MU,Johura FT,Monira S,Watanabe H,Ahmed N,Camilli A,Alam M

    更新日期:2017-10-23 00:00:00

  • The emergence of Klebsiella pneumoniae liver abscess in non-diabetic patients and the distribution of capsular types.

    abstract:BACKGROUND:Klebsiella pneumoniae is the most common pathogen of community-acquired pyogenic liver abscess in East Asia. Diabetes mellitus (DM) is a well-established risk factor for K. pneumoniae liver abscess (KPLA). However, reports regarding the emergence of KPLA in non-diabetic patients are limited. RESULTS:A total...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-016-0128-y

    authors: Chuang C,Fan WC,Lin YT,Wang FD

    更新日期:2016-10-18 00:00:00

  • Exposure to bile influences biofilm formation by Listeria monocytogenes.

    abstract::In the present study we demonstrate that the initial attachment of Listeria monocytogenes cells to plastic surfaces was significantly increased by growth in the presence of bile. Improved biofilm formation was confirmed by crystal violet staining, microscopy and bioluminescence detection of a luciferase-tagged strain....

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-1-11

    authors: Begley M,Kerr C,Hill C

    更新日期:2009-05-28 00:00:00

  • Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination.

    abstract:BACKGROUND:Toll-like receptors (TLRs) are the major pattern recognition receptors that mediate sensing of a wide range of microorganisms. TLR2 forms heterodimers with either TLR1 or TLR6, broadening its ligand diversity against pathogens. TLR1, TLR2 and TLR6 have been implicated in the recognition of Candida albicans, ...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0158-0

    authors: Choteau L,Vancraeyneste H,Le Roy D,Dubuquoy L,Romani L,Jouault T,Poulain D,Sendid B,Calandra T,Roger T,Jawhara S

    更新日期:2017-02-15 00:00:00

  • ESBL-plasmid carriage in E. coli enhances in vitro bacterial competition fitness and serum resistance in some strains of pandemic sequence types without overall fitness cost.

    abstract:Background:Extended spectrum beta lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli infections are of global interest because of their clinical and economic impact. The ESBL resistance genes disseminate through plasmids, and are found in successful global lineages such as ST131 and ST648. The carri...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-018-0243-z

    authors: Ranjan A,Scholz J,Semmler T,Wieler LH,Ewers C,Müller S,Pickard DJ,Schierack P,Tedin K,Ahmed N,Schaufler K,Guenther S

    更新日期:2018-06-15 00:00:00

  • The complete genome sequence of Cronobacter sakazakii ATCC 29544T, a food-borne pathogen, isolated from a child's throat.

    abstract:BACKGROUND:Cronobacter sakazakii is an emerging opportunistic pathogen that is associated with rare but life-threatening cases of severe diseases: meningitis, necrotizing enterocolitis, and sepsis in premature and full-term infants. However, the pathogenesis mechanism of this pathogen remains largely unknown. To determ...

    journal_title:Gut pathogens

    pub_type:

    doi:10.1186/s13099-016-0150-0

    authors: Kim S,Kim YT,Yoon H,Lee JH,Ryu S

    更新日期:2017-01-04 00:00:00

  • Detection, identification and quantification of Campylobacter jejuni, coli and lari in food matrices all at once using multiplex qPCR.

    abstract:BACKGROUND:Thermotolerant Campylobacter jejuni, coli and lari are recognized as leading food-borne pathogens causing an acute bacterial enteritis worldwide. Due to narrow spectrum of their biochemical activity, it is very complicated to distinguish between individual species. For reliable risk assessment, proper incide...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-6-12

    authors: Vondrakova L,Pazlarova J,Demnerova K

    更新日期:2014-05-09 00:00:00

  • Genome characterization of a novel binary toxin-positive strain of Clostridium difficile and comparison with the epidemic 027 and 078 strains.

    abstract:BACKGROUND:Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the binary toxin (CDT), which is generally found in C. difficile 027 (ST1) and/or 078 (ST11) in clinic. However, we isolated a bi...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0191-z

    authors: Peng Z,Liu S,Meng X,Liang W,Xu Z,Tang B,Wang Y,Duan J,Fu C,Wu B,Wu A,Li C

    更新日期:2017-08-07 00:00:00

  • Salmonella enterica serovar Typhimurium adhesion and cytotoxicity during epithelial cell stress is reduced by Lactobacillus rhamnosus GG.

    abstract:BACKGROUND:Physiological stressors may alter susceptibility of the host intestinal epithelium to infection by enteric pathogens. In the current study, cytotoxic effect, adhesion and invasion of Salmonella enterica serovar Typhimurium (S. Typhimurium) to Caco-2 cells exposed to thermal stress (41 degrees C, 1 h) was inv...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-1-14

    authors: Burkholder KM,Bhunia AK

    更新日期:2009-07-09 00:00:00

  • Campylobacter jejuni induces transcellular translocation of commensal bacteria via lipid rafts.

    abstract:BACKGROUND:Campylobacter enteritis represents a risk factor for the development of inflammatory bowel disease (IBD) via unknown mechanisms. As IBD patients exhibit inflammatory responses to their commensal intestinal microflora, factors that induce translocation of commensal bacteria across the intestinal epithelium ma...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-1-2

    authors: Kalischuk LD,Inglis GD,Buret AG

    更新日期:2009-02-03 00:00:00

  • Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

    abstract:BACKGROUND:Shigellosis is an acute form of gastroenteritis caused by the bacteria belonging to the genus Shigella. It is the most common cause of morbidity and mortality in children. Shigella belongs to the family Enterobactericeae, which is a Gram-negative and rod shaped bacterium. In the present study, we report the ...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-6-28

    authors: Kaur G,Sathyabama S,Arora A,Verma S,Mubin N,Agrewala JN,Mayilraj S

    更新日期:2014-07-11 00:00:00

  • Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7.

    abstract:BACKGROUND:Shiga toxin (Stx) producing Escherichia coli (E. coli) (STEC) is the most frequent cause of diarrhoea-positive haemolytic uraemic syndrome (D + HUS) in humans. In 2011, a huge outbreak with an STEC O104:H4 strain in Germany highlighted the limited possibilities for causative treatment of this syndrome. The r...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0179-8

    authors: Wöchtl B,Gunzer F,Gerner W,Gasse H,Koch M,Bagó Z,Ganter M,Weissenböck H,Dinhopl N,Coldewey SM,von Altrock A,Waldmann KH,Saalmüller A,Zimmermann K,Steinmann J,Kehrmann J,Klein-Hitpass L,Blom J,Ehricht R,Engelmann I,

    更新日期:2017-05-25 00:00:00

  • Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: part III - convergence toward clinical trials.

    abstract::Rapid scientific and technological advances have allowed for a more detailed understanding of the relevance of intestinal microbiota, and the entire body-wide microbiome, to human health and well-being. Rodent studies have provided suggestive evidence that probiotics (e.g. lactobacillus and bifidobacteria) can influen...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-5-4

    authors: Bested AC,Logan AC,Selhub EM

    更新日期:2013-03-16 00:00:00

  • Multiple etiologies of infectious diarrhea and concurrent infections in a pediatric outpatient-based screening study in Odisha, India.

    abstract:BACKGROUND:There are multiple etiologies responsible for infectious gastroenteritis causing acute diarrhea which are often under diagnosed. Also acute diarrhea is one of the major causes of morbidity and mortality among children less than 5 years of age. METHODS:In our study, fecal samples (n = 130) were collected fro...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0166-0

    authors: Shrivastava AK,Kumar S,Mohakud NK,Suar M,Sahu PS

    更新日期:2017-04-11 00:00:00

  • Effects of Escherichia coli Nissle 1917 and Ciprofloxacin on small intestinal epithelial cell mRNA expression in the neonatal piglet model of human rotavirus infection.

    abstract::We evaluated the effects of the probiotic Escherichia coli Nissle 1917 (EcN) and the antibiotic Ciprofloxacin (Cipro) on mRNA expression of intestinal epithelial cells (IEC) in gnotobiotic (Gn) piglets colonized with a defined commensal microflora (DMF) and inoculated with human rotavirus (HRV) that infects IECs. We a...

    journal_title:Gut pathogens

    pub_type:

    doi:10.1186/s13099-016-0148-7

    authors: Paim FC,Langel SN,Fischer DD,Kandasamy S,Shao L,Alhamo MA,Huang HC,Kumar A,Rajashekara G,Saif LJ,Vlasova AN

    更新日期:2016-12-13 00:00:00

  • Interaction between Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium avium subspecies paratuberculosis with the enteric glia and microglial cells.

    abstract:BACKGROUND:We investigated the interaction of Mycobacterium avium subspecies paratuberculosis, M. bovis and M. tuberculosis and different glial cells (enteric glial and microglial cells) in order to evaluate the infecting ability of these microorganisms and the effects produced on these cells, such as the evaluation of...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-3-19

    authors: Cannas S,Molicotti P,Bua A,Usai D,Sechi LA,Scanu AM,Blasi E,Zanetti S

    更新日期:2011-12-09 00:00:00

  • High contiguity genome sequence of a multidrug-resistant hospital isolate of Enterobacter hormaechei.

    abstract:Background:Enterobacter hormaechei is an important emerging pathogen and a key member of the highly diverse Enterobacter cloacae complex. E. hormaechei strains can persist and spread in nosocomial environments, and often exhibit resistance to multiple clinically important antibiotics. However, the genomic regions that ...

    journal_title:Gut pathogens

    pub_type:

    doi:10.1186/s13099-019-0288-7

    authors: Monahan LG,DeMaere MZ,Cummins ML,Djordjevic SP,Roy Chowdhury P,Darling AE

    更新日期:2019-02-13 00:00:00

  • Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta).

    abstract:UNLABELLED: BACKGROUND:Helicobacter pylori are successful colonizers of the human gastric mucosa. Colonization increases the risk of peptic ulcer disease and adenocarcinoma. However, potential benefits of H. pylori colonization include protection against early-onset asthma and against gastrointestinal infections. Camp...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-4-9

    authors: Kienesberger S,Perez-Perez GI,Rivera-Correa JL,Tosado-Acevedo R,Li H,Dubois A,Gonzalez-Martinez JA,Dominguez-Bello MG,Blaser MJ

    更新日期:2012-08-24 00:00:00

  • Single-nucleotide polymorphism typing analysis for molecular subtyping of Salmonella Tennessee isolates associated with the 2007 nationwide peanut butter outbreak in the United States.

    abstract:BACKGROUND:In 2007, a nationwide Salmonella Tennessee outbreak occurred via contaminated peanut butter. Here, we developed a single-nucleotide polymorphism (SNP)-typing method for S. Tennessee to determine the clonal subtypes of S. Tennessee that were associated with the peanut butter outbreak. METHODS AND RESULTS:One...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-017-0176-y

    authors: Dong HJ,Cho S,Boxrud D,Rankin S,Downe F,Lovchik J,Gibson J,Erdman M,Saeed AM

    更新日期:2017-05-01 00:00:00

  • The impact of Rhodiola rosea on the gut microbial community of Drosophila melanogaster.

    abstract:Background:The root extract of Rhodiola rosea has historically been used in Europe and Asia as an adaptogen, and similar to ginseng and Shisandra, shown to display numerous health benefits in humans, such as decreasing fatigue and anxiety while improving mood, memory, and stamina. A similar extract in the Rhodiola fami...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-018-0239-8

    authors: Labachyan KE,Kiani D,Sevrioukov EA,Schriner SE,Jafari M

    更新日期:2018-03-20 00:00:00

  • Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice.

    abstract:BACKGROUND:Recently, we found that the probiotic strain Bacillus coagulans GBI-30, 6086 (GanedenBC30) improved indices of Clostridium difficile (C. difficile)-induced colitis in mice (Fitzpatrick et al., Gut Pathogens, 2011). Our goal was to determine if BC30 could also prevent the recurrence of C. difficile-induced co...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-4-13

    authors: Fitzpatrick LR,Small JS,Greene WH,Karpa KD,Farmer S,Keller D

    更新日期:2012-10-22 00:00:00

  • Transcriptome changes and polymyxin resistance of acid-adapted Escherichia coli O157:H7 ATCC 43889.

    abstract:BACKGROUND:Acid treatment is commonly used for controlling or killing pathogenic microorganisms on medical devices and environments; however, inadequate acid treatment may cause acid tolerance response (ATR) and offer cross-protection against environmental stresses, including antimicrobials. This study aimed to charact...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-020-00390-5

    authors: Hwang D,Kim SM,Kim HJ

    更新日期:2020-12-01 00:00:00

  • Stool cultures show a lack of impact in the management of acute gastroenteritis for hospitalized patients in the Bronx, New York.

    abstract:Background:Acute gastroenteritis (AGE) is diagnosed with a presentation of > 1 episode of vomiting and > 3 episodes of diarrhea in a 24-h period. Treatment is supportive, however, in severe cases antibacterial treatment may be indicated. Stool cultures can detect the responsible pathogenic bacteria and can guide antibi...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-020-00369-2

    authors: Fraij O,Castro N,de Leon Castro LA,Brandt LJ

    更新日期:2020-06-22 00:00:00

  • Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease.

    abstract::The two-stage neuroinflammatory process, containment and progression, proposed to underlie neurodegeneration may predicate on systemic inflammation arising from the gastrointestinal tract. Helicobacter infection has been described as one switch in the pathogenic-circuitry of idiopathic parkinsonism (IP): eradication m...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-1-20

    authors: Charlett A,Dobbs RJ,Dobbs SM,Weller C,Ibrahim MA,Dew T,Sherwood R,Oxlade NL,Plant JM,Bowthorpe J,Lawson AJ,Curry A,Peterson DW,Bjarnason IT

    更新日期:2009-11-26 00:00:00

  • Bacteriophage-encoded shiga toxin gene in atypical bacterial host.

    abstract:BACKGROUND:Contamination from fecal bacteria in recreational waters is a major health concern since bacteria capable of causing human disease can be found in animal feces. The Dog Beach area of Ocean Beach in San Diego, California is a beach prone to closures due to high levels of fecal indicator bacteria (FIB). A pote...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-3-10

    authors: Casas V,Sobrepeña G,Rodriguez-Mueller B,Ahtye J,Maloy SR

    更新日期:2011-07-07 00:00:00

  • Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells.

    abstract:BACKGROUND:Recent epidemiological analyses have implicated acute Campylobacter enteritis as a factor that may incite or exacerbate inflammatory bowel disease (IBD) in susceptible individuals. We have demonstrated previously that C. jejuni disrupts the intestinal barrier function by rapidly inducing epithelial transloca...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/1757-4749-2-14

    authors: Kalischuk LD,Leggett F,Inglis GD

    更新日期:2010-11-01 00:00:00

  • Exosomal miRNAs in hepatitis B virus related liver disease: a new hope for biomarker.

    abstract::The World Health Organisation, in its 2019 progress report on HIV, viral hepatitis and STDs indicates that 257 million people are afflicted with chronic HBV infections, of which, 1 million patients lose their lives every year due to HBV related chronic liver diseases including serious complications such as liver cirrh...

    journal_title:Gut pathogens

    pub_type: 杂志文章,评审

    doi:10.1186/s13099-020-00353-w

    authors: Bandopadhyay M,Bharadwaj M

    更新日期:2020-04-24 00:00:00

  • Stool and sputum microbiome during quinolone prophylaxis of spontaneous bacterial peritonitis: an exploratory study.

    abstract:Introduction:Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP. Yet, the impact of long-term antibiotic prophylaxis on the microbiome of these patients is poorly characterized. Methods:Patients with liver cirrhosis receiv...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-020-00389-y

    authors: Mücke MM,Rüschenbaum S,Mayer A,Mücke VT,Schwarzkopf KM,Zeuzem S,Kehrmann J,Scholtysik R,Lange CM

    更新日期:2020-10-30 00:00:00

  • Extensive inter-strain diversity among clinical isolates of Shigella flexneri with reference to its serotype, virulence traits and plasmid incompatibility types, a study from south India over a 6-year period.

    abstract:Background:Shigella has evolved as a result of acquiring extragenetic material through horizontal gene exchange. These aid in the rapid emergence of bacterial inter-strain diversity in virulence factors and serotype variants through O-antigenic switching. Plasmid incompatibility typing of isolates is insightful in unde...

    journal_title:Gut pathogens

    pub_type: 杂志文章

    doi:10.1186/s13099-019-0314-9

    authors: Das A,Mandal J

    更新日期:2019-06-14 00:00:00

  • Comparative genomic analysis reveals genetic features related to the virulence of Bacillus cereus FORC_013.

    abstract:BACKGROUND:Bacillus cereus is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of B. cereus FORC_013 isolated from fried eel in South Korea. To extend our understanding of the genomic characteristics of FORC_013, we conducted a comparative ...

    journal_title:Gut pathogens

    pub_type:

    doi:10.1186/s13099-017-0175-z

    authors: Koo HJ,Ahn S,Chung HY,Kim S,Kim K,Ryu S,Lee JH,Choi SH,Kim H

    更新日期:2017-05-15 00:00:00