Abstract:
:This article reviews the current options in orthobiologics for the clinical treatment of knee osteoarthritis (OA). We describe a new model of knee OA that fills the gap in our understanding of it as a purely traumatic and/or inflammation-induced cartilage degenerative condition, to a current model of multinodal pathophysiology. We discuss graft choice and patient selection in the current state of understanding of the treatment of knee OA in a tissue engineering model with orthobiologics. We present a sample treatment algorithm and decision nest for deciding how to proceed with patient care.
journal_name
Phys Med Rehabil Clin N Amauthors
Crane DM,Oliver KS,Bayes MCdoi
10.1016/j.pmr.2016.07.004subject
Has Abstractpub_date
2016-11-01 00:00:00pages
985-1002issue
4eissn
1047-9651issn
1558-1381pii
S1047-9651(16)30062-6journal_volume
27pub_type
杂志文章,评审abstract::Traumatic spinal cord injury (SCI) often results in several life-altering impairments, including paralysis, sensory loss, and neurogenic bowel/bladder dysfunction. Some of these SCI-related conditions can be accommodated with compensatory strategies. Perhaps no SCI-associated condition is more troublesome and recalcit...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2020.03.004
更新日期:2020-08-01 00:00:00
abstract::Neuromuscular disorders associated with monoclonal gammopathies are usually uncovered in approximately 10% of patients presenting with peripheral neuropathy complaints. This discovery should prompt further evaluation for underlying plasma cell dyscrasias. The most frequent monoclonal disorders associated with neuropat...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2007.10.005
更新日期:2008-02-01 00:00:00
abstract::Visual dysfunctions and symptoms are commonly experienced after even mild traumatic brain injury (TBI) despite excellent visual acuity. All individuals who have experienced a TBI/concussion should be screened for vision symptoms and visual dysfunction. A TBI-specific eye examination is necessary to identify the visual...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2018.09.001
更新日期:2019-02-01 00:00:00
abstract::Foot and ankle injuries account for nearly one-third of running injuries. Achilles tendinopathy, plantar fasciopathy, and ankle sprains are 3 of the most common types of injuries sustained during training. Other common injuries include other tendinopathies of the foot and ankle, bone stress injuries, nerve conditions ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2015.08.007
更新日期:2016-02-01 00:00:00
abstract::Baseball players place significant stress across their shoulders and elbows during the throwing motion, causing unique patterns of injuries in the overhead throwing athlete. Specific nerve injuries include suprascapular neuropathy, quadrilateral space syndrome, and cubital tunnel syndrome. Nonoperative treatment inclu...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pmr.2008.10.007
更新日期:2009-02-01 00:00:00
abstract::Rehabilitation and regenerative medicine therapies has shown improved outcomes for tissue regeneration. Regenerative rehabilitation guides protocols regarding when to start therapy, types of stimuli administered, and graded exercise programs, taking into account biological factors and technologies designed to optimize...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2016.07.002
更新日期:2016-11-01 00:00:00
abstract::Sports and recreational activities are associated with a variety of injuries. Although many of these injuries are musculoskeletal in nature, both the peripheral nervous system and the central nervous system are at risk for injury as well. This article examines the incidence of nervous system injuries in particular spo...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pmr.2008.10.002
更新日期:2009-02-01 00:00:00
abstract::Chronic pain associated with traumatic spinal cord injury (SCI) can be quite challenging to the physiatrist. This highly prevalent condition within the SCI population requires an appropriate evaluative approach including a thorough history, a targeted physical examination, and appropriate use of diagnostic testing. Th...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2014.01.002
更新日期:2014-05-01 00:00:00
abstract::CRF is indisputably a significant problem with important public health and medical economic implications. As the prevalence of cancer survivorship grows, the impact of CRF will increase. Physiatrists have not historically played an active role in caring for affected patients. In the author's opinion, this is unfortuna...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2008.12.005
更新日期:2009-05-01 00:00:00
abstract::Restrictive lung disease occurs commonly in patients with neuromuscular disease. The earliest sign of respiratory compromise in the patient with neuromuscular disease is nocturnal hypoventilation, which progresses over time to include daytime hypoventilation and eventually the need for full-time mechanical ventilation...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2012.08.010
更新日期:2012-11-01 00:00:00
abstract::As public demand for complementary and alternative medicine increases,it is important for physical medicine and rehabilitation physicians to have some basic understanding of complementary and alternative medicine or at least to appreciate some of the approved indications so that appropriate referrals can be made. Beca...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/S1047-9651(03)00129-3
更新日期:2004-11-01 00:00:00
abstract::Chronic pelvic pain is a common condition. Establishing a diagnosis can be complicated by the interplay between various organ systems, including urologic, gynecologic, gastrointestinal, neurologic, endocrinological, psychological, and musculoskeletal. Frequently, the patient will have seen multiple providers and under...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2018.06.011
更新日期:2018-11-01 00:00:00
abstract::Ambulation requires significant motor coordination. Because of inherent differences in body proportions, level of coordination, motivation, and other factors, each individual gait pattern is unique. However, despite the existence of these individual differences that contribute to each person's own unique walking style...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2012.11.010
更新日期:2013-05-01 00:00:00
abstract::This article provides a critical review of what is currently known concerning the nature and scope of depression in persons who have MS. It begins with a discussion of relevant terminology,which is followed by a summary of the research literature concern-ing the prevalence; severity; and risk factors for, and impact o...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2005.01.010
更新日期:2005-05-01 00:00:00
abstract::Evidence supporting the use of specific physical agents in the management of chronic pain conditions is not definitive; it is largely incomplete and sometimes contradictory. However, the use of agents in chronic pain management programs is common. Within the broad use of physical agents, they are rarely the sole modal...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2005.12.007
更新日期:2006-05-01 00:00:00
abstract::Postoperative management of the lower extremity amputation continues to evolve as a crucial first step in amputee rehabilitation. Although the major goals of early rehabilitation remain fairly constant, external forces continually pressure the rehabilitation team to complete these goals within shorter time frames. The...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2005.10.009
更新日期:2006-02-01 00:00:00
abstract::These cases represent individuals who feel they have a severe impairment and are "disabled." They have been labeled with fibromyalgia. They are truly distressed. Their symptoms, their courses, are more chronic and refractory than those of medically ill patients, and they are high users of medical services, laboratory ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::Expert opinion on life expectancy must make reasonable factual assumptions, which entails finding a proper group to which the individual being assessed will be compared, as well as use of appropriate and reliable technical methods. Reasonable judgment should be exercised in the selection of the studies employed. A sch...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2013.03.007
更新日期:2013-08-01 00:00:00
abstract::Advances in medical and surgical care over the past 20 years have resulted in children who formerly would have died at birth or in infancy now surviving into adulthood, many with significant, permanent physical disabilities, including those due to cerebral palsy (CP). Increased awareness of these problems is needed by...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2009.06.009
更新日期:2009-08-01 00:00:00
abstract::Most knee structures can be accurately targeted using ultrasound guidance. These structures are usually superficial, and the overlying soft tissues are mobile and compressible, facilitating excellent visualization with a high-frequency linear array transducer. The circumferential accessibility to the knee affords flex...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2016.04.010
更新日期:2016-08-01 00:00:00
abstract::Volleyball has become one of the world's most popular participatory sports in recent years. There are many dynamic skills and movements needed to play the game. As a result, many overuse and traumatic injuries to the extremities and back may occur. This article addresses the history of the sport and its terminology. C...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1999-02-01 00:00:00
abstract::The history and physical examination are an essential component in the assessment of patients with lumbar spinal stenosis. The differential diagnosis is broad, and many conditions may be ruled out with a thorough office evaluation. Peripheral neuropathy, arteriovascular disease, and hip arthrosis are common entities w...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(02)00049-9
更新日期:2003-02-01 00:00:00
abstract::Although brain magnetic resonance (MR) imaging is increasingly being used as an objective outcome measure in treatment trials for multiple sclerosis (MS), findings correlating conventional MR imaging and disabilities in established MS have been inconsistent. In some studies, measures of MR lesion status, such as numbe...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract::Thirty percent of persons with multiple sclerosis (pwMS) require caregiving owing to their disability, and 80% of care to pwMS is provided by informal unpaid caregivers. The average caregiver is male, in a spousal/partner relationship with the pwMS, and provides more than 4 hours per day of care for many years. The ph...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2013.06.007
更新日期:2013-11-01 00:00:00
abstract::This article has briefly highlighted the area of sport psychology as it relates to performance psychology skills (mental training), including a historical overview and current topics overview. The use of mental training skills may be of interest to the practicing physical medicine and rehabilitation professional in th...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.pmr.2006.05.007
更新日期:2006-08-01 00:00:00
abstract::Neuromuscular electrical stimulation may have an important role in improving the motor function of stroke survivors. Active, repetitive movement training mediated by transcutaneous cyclic and EMG-triggered NMES may facilitate the motor recovery of stroke survivors. Multicenter, double-blinded, randomized clinical tria...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(02)00051-7
更新日期:2003-02-01 00:00:00
abstract::Every examination of disability among children must first grapple with definition of disability. The challenges to identifying disability among children involve not only determining the appropriate paradigm for defining disability, but also applying that paradigm to children in a meaningful way. This discussion of the...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(02)00043-8
更新日期:2002-11-01 00:00:00
abstract::EBP is not a new concept. To practice using the newest and best research evidence, clinicians must have the knowledge and skills to find and appraise the quality of the evidence. This process starts with the formulation of a focused question, followed by an effective search for the best evidence, critical appraisal of...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(02)00027-x
更新日期:2002-11-01 00:00:00
abstract::To be accurate with chronic pain assessment, the medical examiner should be alert to specific diagnoses in addition to global markers of decreased function associated with chronic pain, such as disability and depression. The key to accurate assessment is to avoid making assumptions before doing a complete history and ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2014.12.009
更新日期:2015-05-01 00:00:00
abstract::Conservative management of low back pain includes the use of lumbar epidural steroid injections, which have become increasingly more popular in the last 20 years. The body of literature regarding the efficacy of these injections is vast, conflicting, and difficult to summarize. This article reviews the updated evidenc...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2010.10.006
更新日期:2011-02-01 00:00:00