Recombinant antibodies for specific detection of clostridial [Fe-Fe] hydrogenases.

abstract：:A fracture is the most dangerous complication of osteoporosis in patients because the associated disability and mortality rates are high. Osteoporosis impairs fracture healing and prognosis, but how intramembranous ossification (IO) or endochondral ossification (EO) during fracture healing are affected and whether the...

journal_title：Scientific reports

authors： Zhang H,Shi X,Wang L,Li X,Zheng C,Gao B,Xu X,Lin X,Wang J,Lin Y,Shi J,Huang Q,Luo Z,Yang L

更新日期：2018-03-01 00:00:00

abstract：:Earlier studies showed that endogenous estrogens have neuroprotective effect against oxidative damage. The present study seeks to investigate the protective effect of various endogenous estrogen metabolites against oxidative neurotoxicity in vitro and in vivo. Using immortalized mouse hippocampal neuronal cells as an ...

journal_title：Scientific reports

authors： Choi HJ,Lee AJ,Kang KS,Song JH,Zhu BT

更新日期：2020-04-29 00:00:00

abstract：:In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal chromatography (COFRADIC), were performed using tissue samples from th...

journal_title：Scientific reports

authors： Brea D,Agulla J,Staes A,Gevaert K,Campos F,Sobrino T,Blanco M,Dávalos A,Castillo J,Ramos-Cabrer P

更新日期：2015-07-08 00:00:00

abstract：:The spatial distributions of diverse facilities are often understood in terms of the optimization of the commute distance or the economic profit. Incorporating more general objective functions into such optimization framework may be useful, helping the policy decisions to meet various social and economic demands. As a...

journal_title：Scientific reports

authors： Lee MJ,Kim K,Son J,Lee DS

更新日期：2020-05-25 00:00:00

abstract：:Recent breakthrough of novel hierarchic materials, orchestrated through oriented attachment of crystal subunits, opened questions on what is the mechanism of their self-assembly. Using rutile-type TiO2, synthesized by hydrothermal reaction of Ti(IV)-butoxide in highly acidic aqueous medium, we uncovered the key proces...

journal_title：Scientific reports

authors： Jordan V,Javornik U,Plavec J,Podgornik A,Rečnik A

更新日期：2016-04-11 00:00:00

abstract：:The association between maternal cadmium (Cd) exposure during pregnancy and the increased risk of fetal growth restriction (FGR) remains controversial. The present study evaluated the association between maternal serum Cd level and risk of small for gestational age (SGA) infants in a Chinese population. The present st...

journal_title：Scientific reports

authors： Wang H,Liu L,Hu YF,Hao JH,Chen YH,Su PY,Fu L,Yu Z,Zhang GB,Wang L,Tao FB,Xu DX

更新日期：2016-03-03 00:00:00

abstract：:Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated signals induce the expression of the transcription factor Pax5, which pl...

journal_title：Scientific reports

authors： Abdelrasoul H,Werner M,Setz CS,Okkenhaug K,Jumaa H

更新日期：2018-01-22 00:00:00

abstract：:The western North-Atlantic coast experienced major coastal floods in recent years. Coastal floods are primarily composed of tides and storm surges due to tropical (TCs) and extra-tropical cyclones (ETCs). We present a reanalysis from 1988 to 2015 of extreme sea levels that explicitly include TCs for the western North-...

journal_title：Scientific reports

authors： Muis S,Lin N,Verlaan M,Winsemius HC,Ward PJ,Aerts JCJH

更新日期：2019-03-04 00:00:00

abstract：:The early life stages represent a crucial period that can strongly influence population dynamics. We studied the development of foraging behaviour in the red-footed booby, a tropical seabird with an extensive post-fledging care period (3 to 6 months). Adults and juveniles were observed from shore and tracked at sea us...

journal_title：Scientific reports

authors： Mendez L,Prudor A,Weimerskirch H

更新日期：2017-10-24 00:00:00

abstract：:Multiple sclerosis is a chronic, autoimmune and neurodegenerative disease affecting multiple functional systems and resulting in motor impairments associated with muscle weakness and lack of movement coordination. We quantified upper limb motor deficits with a robot-based assessment including behavioral and muscle syn...

journal_title：Scientific reports

authors： Pellegrino L,Coscia M,Muller M,Solaro C,Casadio M

更新日期：2018-02-01 00:00:00

abstract：:Major depressive disorder (MDD) is a complex condition with unclear pathophysiology. Molecular disruptions within limbic brain regions and the periphery contribute to depression symptomatology and a more complete understanding the diversity of molecular changes that occur in these tissues may guide the development of ...

journal_title：Scientific reports

authors： Hamilton PJ,Chen EY,Tolstikov V,Peña CJ,Picone JA,Shah P,Panagopoulos K,Strat AN,Walker DM,Lorsch ZS,Robinson HL,Mervosh NL,Kiraly DD,Sarangarajan R,Narain NR,Kiebish MA,Nestler EJ

更新日期：2020-10-22 00:00:00

abstract：:Combining spectral imaging with compressive sensing (CS) enables efficient data acquisition by fully utilizing the intrinsic redundancies in natural images. Current compressive multispectral imagers, which are mostly based on array sensors (e.g, CCD or CMOS), suffer from limited spectral range and relatively low photo...

journal_title：Scientific reports

authors： Li Z,Suo J,Hu X,Deng C,Fan J,Dai Q

更新日期：2017-01-27 00:00:00

abstract：:We combine matter-wave interferometry and cavity optomechanics to propose a coherent matter-light interface based on mechanical motion at the quantum level. We demonstrate a mechanism that is able to transfer non-classical features imprinted on the state of a matter-wave system to an optomechanical device, transducing...

journal_title：Scientific reports

authors： Xuereb A,Ulbricht H,Paternostro M

更新日期：2013-11-29 00:00:00

abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

journal_title：Scientific reports

authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

更新日期：2017-09-19 00:00:00

abstract：:Traditional Protein-Protein Interaction (PPI) networks, which use a node and edge representation, lack some valuable information about the mechanistic details of biological processes. Mapping protein structures to these PPI networks not only provides structural details of each interaction but also helps us to find the...

journal_title：Scientific reports

authors： Halakou F,Kilic ES,Cukuroglu E,Keskin O,Gursoy A

更新日期：2017-08-03 00:00:00

abstract：:A single-institution series using a (neo)adjuvant chemotherapy and interdigitated hyperfractionated split-course radiation therapy (CRT) treatment protocol for soft tissue sarcoma was reviewed. Our specific aims were to study recurrence rates and long-term toxicity. Between 1998 and 2016, 89 patients with non-metastat...

journal_title：Scientific reports

authors： Nevala R,Tukiainen E,Tarkkanen M,Böhling T,Blomqvist C,Sampo M

更新日期：2019-05-13 00:00:00

abstract：:Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signalling pathway in cr...

journal_title：Scientific reports

authors： Gu M,Ni H,Sheng X,Pauciullo A,Liu Y,Guo Y

更新日期：2017-07-27 00:00:00

abstract：:Mild cognitive impairment (MCI) is a precursor phase of Alzheimer's disease (AD). As current treatments may be effective only at the early stages of AD, it is important to track MCI patients who will convert to AD. The aim of this study is to develop a high performance semi-mechanism based approach to predict the conv...

journal_title：Scientific reports

authors： Liu H,Zhou X,Jiang H,He H,Liu X,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-07 00:00:00

abstract：:A multi-angle light scattering (MALS) system, combined with chromatographic separation, directly measures the absolute molar mass, size and concentration of the eluate species. The measurement of these crucial properties in solution is essential in basic macromolecular characterization and all research and production ...

journal_title：Scientific reports

authors： Hsieh VH,Wyatt PJ

更新日期：2017-08-30 00:00:00

abstract：:The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography. SMTNL1 deletion was associated...

journal_title：Scientific reports

authors： Turner SR,Chappellaz M,Popowich B,Wooldridge AA,Haystead TAJ,Cole WC,MacDonald JA

更新日期：2019-01-24 00:00:00

abstract：:Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands. Here we investigated the role of OPN in modulating the liver lipidome during regeneration after ...

journal_title：Scientific reports

authors： Nuñez-Garcia M,Gomez-Santos B,Saenz de Urturi D,Mestre D,Gonzalez-Romero F,Buque X,Gutiérrez-de Juan V,Martinez-Chantar ML,Syn WK,Fresnedo O,Aspichueta P

更新日期：2018-10-02 00:00:00

abstract：:Photodynamic therapy is attracting increasing attention, but how to increase its tumor-specificity remains a daunting challenge. Herein we report a theranostic probe (azo-PDT) that integrates pyropheophorbide α as a photosensitizer and a NIR fluorophore for tumor imaging. The two functionalities are linked with a hypo...

journal_title：Scientific reports

authors： Wang C,Wang S,Wang Y,Wu H,Bao K,Sheng R,Li X

更新日期：2020-07-22 00:00:00

abstract：:Spontaneous isopeptide bond formation, a stabilizing posttranslational modification that can be found in gram-positive bacterial cell surface proteins, has previously been used to develop a peptide-peptide ligation technology that enables the polymerization of tagged-proteins catalyzed by SpyLigase. Here we adapted th...

journal_title：Scientific reports

authors： Siegmund V,Piater B,Zakeri B,Eichhorn T,Fischer F,Deutsch C,Becker S,Toleikis L,Hock B,Betz UA,Kolmar H

更新日期：2016-12-16 00:00:00

abstract：:Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors. Progesterone affects cell proliferation and survival via non-genomic effects. In ...

journal_title：Scientific reports

authors： Kasubuchi M,Watanabe K,Hirano K,Inoue D,Li X,Terasawa K,Konishi M,Itoh N,Kimura I

更新日期：2017-07-12 00:00:00

abstract：:Natural Killer cells are innate lymphocytes involved in tumor immunosurveillance. They express activating receptors able to recognize self-molecules poorly expressed on healthy cells but up-regulated upon stress conditions, including transformation. Regulation of ligand expression in tumor cells mainly relays on trans...

journal_title：Scientific reports

authors： Zitti B,Molfetta R,Fionda C,Quatrini L,Stabile H,Lecce M,de Turris V,Ricciardi MR,Petrucci MT,Cippitelli M,Gismondi A,Santoni A,Paolini R

更新日期：2017-09-05 00:00:00

abstract：:Extensive research indicates that inter-sexual selection drives the evolution of complex vocal communication in birds, but parallel lines of evidence are almost entirely absent in mammals. This dearth of evidence, particularly among primates, limits our understanding of the link between sociality and vocal complexity....

journal_title：Scientific reports

authors： Gustison ML,Bergman TJ

更新日期：2016-01-21 00:00:00

abstract：:In populations of Drosophila larvae, both, an aggregation and a dispersal behavior can be observed. However, the mechanisms coordinating larval locomotion in respect to other animals, especially in close proximity and during/after physical contacts are currently only little understood. Here we test whether relevant in...

journal_title：Scientific reports

authors： Otto N,Risse B,Berh D,Bittern J,Jiang X,Klämbt C

更新日期：2016-08-11 00:00:00

abstract：:Computational predictions of double gene knockout effects by flux balance analysis (FBA) have been used to characterized genome-wide patterns of epistasis in microorganisms. However, it is unclear how in silico predictions are related to in vivo epistasis, as FBA predicted only a minority of experimentally observed ge...

journal_title：Scientific reports

authors： Alzoubi D,Desouki AA,Lercher MJ

更新日期：2019-08-14 00:00:00

abstract：:Tau is a Microtubule-associated protein that induces and stabilizes the formation of the Microtubule cytoskeleton and plays an important role in neurodegenerative diseases. The Microtubules binding region of Tau has been determined for a long time but where and how Tau binds to its partner still remain a topic of deba...

journal_title：Scientific reports

authors： Martinho M,Allegro D,Huvent I,Chabaud C,Etienne E,Kovacic H,Guigliarelli B,Peyrot V,Landrieu I,Belle V,Barbier P

更新日期：2018-09-14 00:00:00

abstract：:The intention of this observational study is to show the significant impact of comorbidities and smoking on the outcome in aneurysmal subarachnoid hemorrhage (SAH). During this observational study 203 cases of treatment of ruptured intracranial aneurysms were analyzed. We examined and classified prospectively the 12 m...

journal_title：Scientific reports

authors： Hammer A,Steiner A,Ranaie G,Yakubov E,Erbguth F,Hammer CM,Killer-Oberpfalzer M,Steiner H,Janssen H

更新日期：2018-08-17 00:00:00