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Coping with Loss: Cell Adaptation to Cytoskeleton Disruption.

Abstract：

:Unravelling the role of cytoskeleton regulators may be complicated by adaptations to experimental manipulations. In this issue of Developmental Cell, Cerikan et al. (2016) reveal how acute effects of DOCK6 RhoGEF depletion on RAC1 and CDC42 activation are reversed over time by compensatory mechanisms that re-establish cellular homeostasis.

journal_name

Dev Cell

journal_title

Developmental cell

authors

McGarry DJ,Olson MF

doi

10.1016/j.devcel.2016.09.020

subject

Has Abstract

pub_date

2016-10-10 00:00:00

pages

3-4

issue

1

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(16)30670-0

journal_volume

39

pub_type

评论,杂志文章

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