Proteome Profiling of Urinary Exosomes Identifies Alpha 1-Antitrypsin and H2B1K as Diagnostic and Prognostic Biomarkers for Urothelial Carcinoma.

abstract：:Biological armors such as mollusk shells have long been recognized and studied for their values in inspiring novel designs of engineering materials with higher toughness and strength. However, no material is invincible and biological armors also have their rivals. In this paper, our attention is focused on the teeth o...

journal_title：Scientific reports

authors： Fu J,He C,Xia B,Li Y,Feng Q,Yin Q,Shi X,Feng X,Wang H,Yao H

更新日期：2016-03-22 00:00:00

abstract：:In arthropods, retinoid X receptor (RXR) is a highly conserved nuclear hormone receptor. By forming a heterodimeric complex with the ecdysone receptor (EcR), RXR is known to be vital importance for various physiological processes. However, in comparison to EcR, the RXR signaling pathway and its roles in crustacean rep...

journal_title：Scientific reports

authors： Gong J,Huang C,Shu L,Bao C,Huang H,Ye H,Zeng C,Li S

更新日期：2016-03-24 00:00:00

abstract：:The metal-to-insulator transition (MIT) closest to room temperature of 68-70 °C as shown by vanadium oxide (VO2), compared with other transition metal oxides, makes it a potential candidate for smart window coating. We have successfully fabricated a potential smart window device after the optimum design of a multilaye...

journal_title：Scientific reports

authors： Behera MK,Williams LC,Pradhan SK,Bahoura M

更新日期：2020-02-04 00:00:00

abstract：:Present study is designed for the synthesis, characterization and corrosion inhibition behavior of two diamine aromatic epoxy pre-polymers (DAEPs) namely, N1,N1,N2,N2-tetrakis (oxiran-2-ylmethyl) benzene-1,2-diamine (DAEP1) and 4-methyl-N1,N1,N2,N2-tetrakis (oxiran-2-ylmethyl) benzene-1,2-diamine (DAEP2) for carbon st...

journal_title：Scientific reports

authors： Dagdag O,Safi Z,Hsissou R,Erramli H,El Bouchti M,Wazzan N,Guo L,Verma C,Ebenso EE,El Harfi A

更新日期：2019-08-12 00:00:00

abstract：:Our goal was to evaluate early results of the clinical application of autologous whole bone marrow stem cell transplantation (AWBMSCT) for critical limb ischemia (CLI) in patients with Buerger's disease. We retrospectively analyzed the data of 58 limbs of 37 patients (mean age, 43.0 years; range, 28-63 years; male, 91...

journal_title：Scientific reports

authors： Heo SH,Park YS,Kang ES,Park KB,Do YS,Kang KS,Kim DI

更新日期：2016-01-21 00:00:00

abstract：:Multiexcitonic transitions and emission of several photons per excitation comprise a very attractive feature of semiconductor quantum dots for optoelectronics applications. However, these higher-order radiative processes are usually quenched in colloidal quantum dots by Auger and other nonradiative decay channels. To ...

journal_title：Scientific reports

authors： Matsuzaki K,Vassant S,Liu HW,Dutschke A,Hoffmann B,Chen X,Christiansen S,Buck MR,Hollingsworth JA,Götzinger S,Sandoghdar V

更新日期：2017-02-14 00:00:00

abstract：:CRISPR-Cas9-mediated gene interference (CRISPRi) and activation (CRISPRa) approaches hold promise for functional gene studies and genome-wide screens in human pluripotent stem cells (hPSCs). However, in contrast to CRISPR-Cas9 nuclease approaches, the efficiency of CRISPRi/a depends on continued expression of the dead...

journal_title：Scientific reports

authors： Hazelbaker DZ,Beccard A,Angelini G,Mazzucato P,Messana A,Lam D,Eggan K,Barrett LE

更新日期：2020-01-20 00:00:00

abstract：:RNA-based three-way junctions (3WJs) are naturally occurring structures found in many functional RNA molecules including rRNA, tRNA, snRNA and ribozymes. 3WJs are typically characterized as resulting from an RNA molecule folding back on itself in cis but could also form in trans when one RNA, for instance a microRNA b...

journal_title：Scientific reports

authors： Doyle F,Lapsia S,Spadaro S,Wurz ZE,Bhaduri-McIntosh S,Tenenbaum SA

更新日期：2017-03-28 00:00:00

abstract：:Nanoporous structures have proven as an effective way for enhanced electrochromic performance by providing a large surface area can get fast ion/electron transfer path, leading to larger optical modulation and fast response time. Herein, for the first time, application of vacuum cathodic arc plasma (CAP) deposition te...

journal_title：Scientific reports

authors： Chen PW,Chang CT,Ko TF,Hsu SC,Li KD,Wu JY

更新日期：2020-05-21 00:00:00

abstract：:During germ cell development, epigenetic modifications undergo extensive remodeling. Abnormal epigenetic modifications usually result in germ cell loss and reproductive defect. Prmt5 (Protein arginine methyltransferase 5) encodes a protein arginine methyltransferase which has been demonstrated to play important roles ...

journal_title：Scientific reports

authors： Wang Y,Zhu T,Li Q,Liu C,Han F,Chen M,Zhang L,Cui X,Qin Y,Bao S,Gao F

更新日期：2015-06-15 00:00:00

abstract：:We have studied the intrinsic fluorescence spectra of a monomeric variant of human transthyretin (M-TTR), a protein involved in the transport of the thyroid hormone and retinol and associated with various forms of amyloidosis, extending our analysis to the second order derivative of the spectra. This procedure allowed...

journal_title：Scientific reports

authors： Jazaj D,Ghadami SA,Bemporad F,Chiti F

更新日期：2019-07-29 00:00:00

abstract：:One-year time series of current velocities and hydrographic parameters based on four deep moorings deployed east of the Luzon Strait are employed to study the deep current at the western boundary (DCWB) of the northern Philippine Basin. While the mean current is relatively weak, the DCWB is highly variable on an intra...

journal_title：Scientific reports

authors： Zhou C,Zhao W,Tian J,Yang Q,Huang X,Zhang Z,Qu T

更新日期：2018-09-25 00:00:00

abstract：:Nanostructure based color filtering has been considered an attractive replacement for current colorant pigmentation in the display technologies, in view of its increased efficiencies, ease of fabrication and eco-friendliness. For such structural filtering, iridescence relevant to its angular dependency, which poses a ...

journal_title：Scientific reports

authors： Shrestha VR,Lee SS,Kim ES,Choi DY

更新日期：2014-05-12 00:00:00

abstract：:In sugarcane (Saccharum spp. hybrid) breeding, introgression of useful genes via intergeneric hybridization is a powerful strategy for improving the crop productivity. Erianthus arundinaceus shows great potential in terms of useful traits; however, little is known about the cytogenetic and agronomic characteristics of...

journal_title：Scientific reports

authors： Pachakkil B,Terajima Y,Ohmido N,Ebina M,Irei S,Hayashi H,Takagi H

更新日期：2019-02-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xu S,Fan S,Fang S,Lang X,Wang Y,Chen J

更新日期：2020-05-26 00:00:00

abstract：:Networks are widely used as a tool for describing diverse real complex systems and have been successfully applied to many fields. The distance between networks is one of the most fundamental concepts for properly classifying real networks, detecting temporal changes in network structures, and effectively predicting th...

journal_title：Scientific reports

authors： Shimada Y,Hirata Y,Ikeguchi T,Aihara K

更新日期：2016-10-11 00:00:00

abstract：:Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...

journal_title：Scientific reports

authors： Aguiar AS Jr,Speck AE,Amaral IM,Canas PM,Cunha RA

更新日期：2018-07-16 00:00:00

abstract：:Spectrometers now offer the field strengths necessary to visualize mammalian cells but were not designed to accommodate imaging of live tissues. As such, spectrometers pose significant challenges--the most evident of which are spatial limitations--to conducting experiments in living tissue. This limitation becomes pro...

journal_title：Scientific reports

authors： Flint JJ,Menon K,Hansen B,Forder J,Blackband SJ

更新日期：2015-12-15 00:00:00

abstract：:KaiC, the core oscillator of the cyanobacterial circadian clock, is composed of an N-terminal C1 domain and a C-terminal C2 domain, and assembles into a double-ring hexamer upon ATP binding. Cyclic phosphorylation and dephosphorylation at Ser431 and Thr432 in the C2 domain proceed with a period of approximately 24 h i...

journal_title：Scientific reports

authors： Mukaiyama A,Furuike Y,Abe J,Koda SI,Yamashita E,Kondo T,Akiyama S

更新日期：2018-06-11 00:00:00

abstract：:This study aimed to detect the spatial distribution and high-risk clusters of female breast cancer mortality for the years 2011 to 2013 in Shandong Province, China. The urban-rural difference in the spatial distribution and clusters of disease mortality were also examined. Breast cancer mortality data were obtained fr...

journal_title：Scientific reports

authors： Chu J,Zhou C,Guo X,Sun J,Xue F,Zhang J,Lu Z,Fu Z,Xu A

更新日期：2017-03-07 00:00:00

abstract：:High content of organic matter in the downstream of watersheds underscored the severity of non-point source (NPS) pollution. The major objectives of this study were to characterize and quantify dissolved organic matter (DOM) in watersheds affected by NPS pollution, and to apply self-organizing map (SOM) and parallel f...

journal_title：Scientific reports

authors： Zhang Y,Liang X,Wang Z,Xu L

更新日期：2015-11-03 00:00:00

abstract：:Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum Tower Hospital, Jiangsu province of eastern China. Relative telomere length (RTL) of...

journal_title：Scientific reports

authors： Weng Q,Deng K,Wu F,Gan M,Li J,Dai Y,Jiang Y,Chen J,Dai J,Ma H,Hu Z,Shen H,Du J,Hu Y,Jin G

更新日期：2019-06-11 00:00:00

abstract：:Dickeya zeae is the causal agent of rice foot rot disease, which has recently become a great threat to rice planting countries and regions. The pathogen produces a family of phytotoxins named zeamines that is critical for bacterial virulence, but little is known about the signaling pathways and regulatory mechanisms t...

journal_title：Scientific reports

authors： Lv M,Chen Y,Liao L,Liang Z,Shi Z,Tang Y,Ye S,Zhou J,Zhang L

更新日期：2018-01-10 00:00:00

abstract：:Statins are a class of oral drugs that are widely used for treatment of hypercholesterolemia. Recent clinical data suggest that chronic use of these drugs increases the frequency of new onset diabetes. Studies to define the risks of statin-induced diabetes and its underlying mechanisms are clearly necessary. We explor...

journal_title：Scientific reports

authors： Kain V,Kapadia B,Misra P,Saxena U

更新日期：2015-09-08 00:00:00

abstract：:Enrofloxacin-loaded docosanoic acid solid lipid nanoparticles (SLNs) with different physicochemical properties were developed to enhance activity against intracellular Salmonella. Their cellular uptake, intracellular elimination and antibacterial activity were studied in RAW 264.7 cells. During the experimental period...

journal_title：Scientific reports

authors： Xie S,Yang F,Tao Y,Chen D,Qu W,Huang L,Liu Z,Pan Y,Yuan Z

更新日期：2017-01-23 00:00:00

abstract：:Chaotic resonance is a phenomenon that can replace the fluctuation source in stochastic resonance from additive noise to chaos. We previously developed a method to control the chaotic state for suitably generating chaotic resonance by external feedback even when the external adjustment of chaos is difficult, establish...

journal_title：Scientific reports

authors： Nobukawa S,Shibata N,Nishimura H,Doho H,Wagatsuma N,Yamanishi T

更新日期：2019-09-02 00:00:00

abstract：:Macrophages are potent immune cells with well-established roles in the response to stress, injury, infection and inflammation. The classically activated macrophages (M1) are induced by lipopolysaccharide (LPS) and express a wide range of pro-inflammatory genes. M2 macrophages are induced by T helper type 2 cytokines s...

journal_title：Scientific reports

authors： Moraes LA,Kar S,Foo SL,Gu T,Toh YQ,Ampomah PB,Sachaphibulkij K,Yap G,Zharkova O,Lukman HM,Fairhurst AM,Kumar AP,Lim LHK

更新日期：2017-12-20 00:00:00

abstract：:Charcot-Marie-Tooth (CMT) is a group of inherited diseases clinically and genetically heterogenous, characterised by length dependent degeneration of axons of the peripheral nervous system. A missense mutation (p.R158H) in the pyruvate dehydrogenase kinase 3 gene (PDK3) has been identified as the genetic cause for an ...

journal_title：Scientific reports

authors： Perez-Siles G,Cutrupi A,Ellis M,Screnci R,Mao D,Uesugi M,Yiu EM,Ryan MM,Choi BO,Nicholson G,Kennerson ML

更新日期：2020-06-05 00:00:00

abstract：:Surface hydrophobicity of silicon with sound durability under mechanical abrasion is highly desirable for practical needs. However, the reported micro-pyramid/nanowires structures suffer from the saturation characteristics of contact angle at around 132 degree, which impede the promotions toward reaching the state of ...

journal_title：Scientific reports

authors： Hsiao M,Chen KY,Chen CY

更新日期：2019-02-07 00:00:00

abstract：:Multiple predatory insect lineages have developed a raptorial lifestyle by which they strike and hold prey using modified forelegs armed with spine-like structures and other integumentary specialisations. However, how structures enabling the raptorial function evolved in insects remains largely hypothetical or inferre...

journal_title：Scientific reports

authors： Pérez-de la Fuente R,Peñalver E

更新日期：2019-09-13 00:00:00