Meconium Peritonitis: Correlation of Antenatal Diagnosis and Postnatal Outcome - An Institutional Experience over 10 Years.

Abstract:

OBJECTIVE:To identify the fetal and neonatal imaging characteristics of meconium peritonitis (MP) and their clinical outcome. We also studied the role of prenatal ultrasound (US) in antenatal diagnosis and its use in predicting the need for surgical intervention postnatally. MATERIAL AND METHODS:We conducted a retrospective analysis of a cohort of 18 infants with MP from April 2004 to March 2014. RESULTS:Prenatal US detected MP-related abnormalities in 15/18 (83.3%) fetuses. The median gestational age at initial diagnosis of MP was 24 weeks (range 19-31). Fetal ascites (93.3%) was the most common prenatal US finding. Of the 18 infants, 12 (66.7%) required surgical intervention. The overall survival rate was 94.4%. All infants with a prenatal US scan showing meconium pseudocyst or bowel dilatation required surgical intervention postnatally. DISCUSSION:A combination of ascites, intraperitoneal calcification, and echogenic bowel on fetal US raises a high suspicion of MP. Surgical intervention is indicated in the presence of meconium pseudocyst on fetal or postnatal US scan. Antenatal US has high specificity (100%) but low sensitivity (22.2%) in detecting meconium pseudocyst. A favorable outcome can be expected with early antenatal diagnosis and timely surgical intervention in a tertiary hospital.

journal_name

Fetal Diagn Ther

authors

Ping LM,Rajadurai VS,Saffari SE,Chandran S

doi

10.1159/000449380

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

57-62

issue

1

eissn

1015-3837

issn

1421-9964

pii

000449380

journal_volume

42

pub_type

杂志文章
  • Cell-Free DNA Analysis in Maternal Blood: Differences in Estimates between Laboratories with Different Methodologies Using a Propensity Score Approach.

    abstract:OBJECTIVES:To evaluate the failure rate and performance of cell-free DNA (cfDNA) testing, mainly in terms of detection rates for trisomy 21, performed by 2 laboratories using different analytical methods. METHODS:cfDNA testing was performed on 2,870 pregnancies with the HarmonyTM Prenatal Test using the targeted digit...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000489124

    authors: Bevilacqua E,Jani JC,Letourneau A,Duiella SF,Kleinfinger P,Lohmann L,Resta S,Cos Sanchez T,Fils JF,Mirra M,Benachi A,Costa JM

    更新日期:2019-01-01 00:00:00

  • Isolated absence of septum pellucidum: prenatal diagnosis and outcome.

    abstract::Septal agenesis is a rare cerebral developmental anomaly characterized by partial or complete absence of the septum pellucidum (ASP). Septal agenesis may be associated with various congenital brain malformations, namely holoprosencephaly, septooptic dysplasia (SOD), schizencephaly or agenesis of the corpus callosum. C...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000338009

    authors: García-Arreza A,García-Díaz L,Fajardo M,Carreto P,Antiñolo G

    更新日期:2013-01-01 00:00:00

  • Identification of Macrosomic, normal and intrauterine growth retarded neonates using the modified Neonatal Growth Assessment Score.

    abstract:OBJECTIVE:Separation of Macrosomic, normal and intrauterine growth retarded (IUGR) neonates using the modified Neonatal Growth Assessment Score (NGAS). METHODS:A sample of 23 neonates with evidence of growth acceleration and 74 neonates classified as normal or IUGR in a previous study was used in this investigation. T...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000074262

    authors: Deter RL,Spence LR

    更新日期:2004-01-01 00:00:00

  • Optimal interval between middle cerebral artery velocity measurements when monitoring pregnancies complicated by red cell alloimmunization.

    abstract:OBJECTIVE:To evaluate the optimal interval between middle cerebral artery (MCA) Doppler measurements when monitoring pregnancies complicated by red cell alloimmunization. METHODS:Thirty-nine fetal blood samplings (FBS) performed on 24 pregnant women with red blood cell alloimmunization followed up using both MCA peak ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000089043

    authors: Bartha JL,Abdel-Fattah SA,Hunter A,Denbow M,Kyle P,Soothill PW

    更新日期:2006-01-01 00:00:00

  • Prenatal sonographic diagnosis of duplicated middle cerebral artery.

    abstract::We report a fetus scanned by color Doppler ultrasound at 37 weeks for suspicion of growth restriction with an extremely rare variation of duplicated middle cerebral artery. Three-dimensional color power Doppler and tomographic ultrasound imaging enhanced our incidental finding. ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000309498

    authors: Ventura W,Nazario C,Ingar J,Huertas E,Limay A,Castillo W

    更新日期:2010-01-01 00:00:00

  • Refining the Prediction and Prevention of Emergency Operative Deliveries with the Fetal Reserve Index.

    abstract::Electronic fetal monitoring (EFM) is a poor predictor of outcomes attributable to delivery problems. Contextualizing EFM by adding maternal, obstetrical, and fetal risk-related information to create an index called the Fetal Reserve Index (FRI) improves the predictive capacity and facilitates the timing of interventio...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000494617

    authors: Britt DW,Evans MI,Schifrin BS,Eden RD

    更新日期:2019-01-01 00:00:00

  • The BS/BSOB Ratio in Aneuploidy Fetuses at 11-13 Weeks Gestation.

    abstract:OBJECTIVE:The posterior fossa of normal fetuses was evaluated and compared with those having chromosomal abnormalities at 11-13+6 weeks' gestation in Chinese population. METHODS:In 518 normal fetuses referred to first trimester screening, fetal brain stem (BS) and brain stem to occipital bone distance (BSOB) were meas...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000366020

    authors: Hsiao CH,Cheng PJ,Shaw SW,Tseng YJ,Chen RC,Chu WC

    更新日期:2015-01-01 00:00:00

  • The Aortic Isthmus: A Significant yet Underexplored Watershed of the Fetal Circulation.

    abstract::The aortic isthmus (AoI) is a unique fetal watershed with a waveform reflecting its complex haemodynamic physiology. The systolic component represents left and right ventricular systolic ejection, and the diastolic component represents comparative downstream vascular impedance between the brachiocephalic and subdiaphr...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000446942

    authors: Tynan D,Alphonse J,Henry A,Welsh AW

    更新日期:2016-01-01 00:00:00

  • Bidirectional communication between neural and cardiac cells in human amniotic fluid.

    abstract:OBJECTIVE:To evaluate whether amniotic fluid cells contain cardiomyocyte- and neuron-like cells. STUDY DESIGN:In this experimental study, cells from human amniotic fluid samples were analyzed for mRNA expression of microtubule-associated protein 2 (MAP-2), vimentin and oxytocin (OT) receptor via RT-PCR. Immunocytochem...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000200016

    authors: Stefanidis K,Loutradis D,Anastasiadou V,Dinopoulou V,Eleni E,Arampatzi E,Lekka K,Mesogitis S,Antsaklis A

    更新日期:2009-01-01 00:00:00

  • Quantification of Posterior Risk Related to Intrapartum FIGO 2015 Criteria for Cardiotocography in the Second Stage of Labor.

    abstract:INTRODUCTION:Intrapartum cardiotocography (CTG) was used for several decades to detect a stressed fetus so that delivery can be expedited to prevent birth asphyxia. The main aim of the study was to calculate the risk of neonatal acidemia (pH ≤ 7.10) according to duration of the 2nd stage of labor and occurrence of the ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000512658

    authors: Cavoretto PI,Seidenari A,Amodeo S,Della Gatta AN,Nale R,Ismail YS,Candiani M,Farina A

    更新日期:2021-01-28 00:00:00

  • Prenatal Growth in Fetuses with Isolated Cyanotic and Non-Cyanotic Congenital Heart Defects.

    abstract:BACKGROUND:Fetal growth may vary significantly in different congenital heart defects (CHDs). OBJECTIVES:To investigate prenatal growth of CHD fetuses and its correlation with classifications based upon expected oxygen delivery to the fetal brain or structural findings. METHODS:Seventy-nine euploid fetuses with isolat...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000493938

    authors: Inversetti A,Fesslova V,Deprest J,Candiani M,Giorgione V,Cavoretto P

    更新日期:2020-01-01 00:00:00

  • Chorioamniotic membrane separation following open fetal surgery: pregnancy outcome.

    abstract:OBJECTIVE:To review the incidence of posthysterotomy chorioamniotic membrane separation and delivery outcome following open fetal surgery [myelomeningocele (MMC); cystic adenomatoid malformation (CCAM); congenital diaphragmatic hernia (CDH); sacrococcygeal teratoma (SCT)]. STUDY DESIGN:Retrospective review of a matern...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000071972

    authors: Wilson RD,Johnson MP,Crombleholme TM,Flake AW,Hedrick HL,King M,Howell LJ,Adzick NS

    更新日期:2003-09-01 00:00:00

  • Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery.

    abstract:OBJECTIVE:To evaluate lower extremity neuromotor function (LENF) and short-term ambulatory potential following fetal myelomeningocele (fMMC) closure. METHODS:Retrospective chart review of 54 children that underwent fMMC closure at our institution prior to the NIHCD-MOMS trial. Neonatal LENF was compared to predicted f...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000197359

    authors: Danzer E,Gerdes M,Bebbington MW,Sutton LN,Melchionni J,Adzick NS,Wilson RD,Johnson MP

    更新日期:2009-01-01 00:00:00

  • Enrichment of fetal nucleated red blood cells from the maternal circulation for prenatal diagnosis: experiences with triple density gradient and MACS based on more than 600 cases.

    abstract:OBJECTIVE:We wanted to obtain statistically relevant data about the efficiency of our method for the isolation of fetal nucleated red blood cells (NRBCs) from the maternal circulation. METHODS:More than 600 samples were investigated using a triple density gradient followed by magnetic separation of anti-CD71-labeled c...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020854

    authors: Gänshirt D,Smeets FW,Dohr A,Walde C,Steen I,Lapucci C,Falcinelli C,Sant R,Velasco M,Garritsen HS,Holzgreve W

    更新日期:1998-09-01 00:00:00

  • Delivery course of macerated stillborn fetuses in the third trimester.

    abstract:AIM:We present and discuss delivery (maternal and fetal) outcome of macerated stillbirths in the third trimester. MATERIAL AND METHODS:In this retrospective observational study, the course of labor was analyzed in 10 stillborn fetuses with a varying grade of maceration during the third trimester. Medical documentation...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000132405

    authors: Habek D

    更新日期:2008-01-01 00:00:00

  • The role of echocardiography in the intraoperative management of the fetus undergoing myelomeningocele repair.

    abstract:INTRODUCTION:Fetal surgery for myelomeningocele (MMC) results in better outcomes compared to postnatal treatment. However, risks are present. We describe our experience with intraoperative fetal echocardiography during repair of MMC and report on the management of serious cardiovascular events. MATERIAL AND METHODS:Th...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000364863

    authors: Rychik J,Cohen D,Tran KM,Szwast A,Natarajan SS,Johnson MP,Moldenhauer JS,Khalek N,Martinez-Poyer J,Flake AW,Hedrick HL,Adzick NS

    更新日期:2015-01-01 00:00:00

  • Human placental growth hormone is increased in maternal serum in pregnancies affected by Down syndrome.

    abstract:OBJECTIVE:To evaluate the relationship between maternal serum levels of human placental growth hormone (hPGH) and fetal Down syndrome at gestational midtrimester. METHODS:We retrospectively analyzed samples of serum from 21 women with Down syndrome pregnancies detected at gestational midtrimester. The samples were obt...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000116743

    authors: Papadopoulou E,Sifakis S,Giahnakis E,Fragouli Y,Karkavitsas N,Koumantakis E,Kalmanti M

    更新日期:2008-01-01 00:00:00

  • On the complication risk of early amniocentesis versus standard amniocentesis.

    abstract::In the last 6 years early amniocentesis for the prenatal diagnosis of chromosome aberrations has been established in many centers worldwide, but knowledge about the gynecological safety of the procedure is sparse. From 1990 to 1995 at the Evangelisches Krankenhaus Oberhausen (Germany) 3,277 early amniocenteses (betwee...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章

    doi:10.1159/000264454

    authors: Eiben B,Hammans W,Hansen S,Trawicki W,Osthelder B,Stelzer A,Jaspers KD,Goebel R

    更新日期:1997-05-01 00:00:00

  • How antenatal ultrasound diagnosis of congenital malformations has contributed to fetal outcome: a 22-year review.

    abstract::We herein reviewed 630 malformed fetuses delivered from 24 weeks of gestation onwards in our institute over the past 22 years. These fetuses were divided into 2 groups: 210 from 1970 to 1982 (group 1) and 420 from 1983 to 1991 (group 2). Twenty-two varieties of congenital malformations were diagnosed antenatally in gr...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263857

    authors: Hori E,Koyanagi T,Yoshizato T,Maeda H,Satoh S,Suita S,Ueda K,Nakano H

    更新日期:1993-11-01 00:00:00

  • Noninvasive Sampling of the Intrauterine Environment in Women with Preterm Labor and Intact Membranes.

    abstract::Spontaneous preterm birth has enormous consequences for newborns, children, and families. Intra-amniotic inflammation (IAI) is the leading cause of spontaneous preterm delivery, mainly at earlier gestational ages. Amniocentesis is the only method used to identify IAI in clinical practice. Although it is an invasive pr...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000480232

    authors: Cobo T,Kacerovsky M,Jacobsson B

    更新日期:2018-01-01 00:00:00

  • Prenatal diagnosis of X-linked ichthyosis using molecular cytogenetics.

    abstract::A case is presented in which X-linked ichthyosis was diagnosed prenatally using fluorescence in situ hybridization. Fetal sex was known by second trimester ultrasound in a woman with very low second trimester MSUE3. All of the 15 maternal peripheral blood metaphase spreads examined displayed two hybridization signals ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264422

    authors: Santolaya-Forgas J,Cohen L,Vengalil S,Field F,Rodriguez A,McCorquadale M,McCorquadale DJ

    更新日期:1997-01-01 00:00:00

  • Are amniotic fluid alpha-fetoprotein levels influenced by the gender in twin pairs?

    abstract:OBJECTIVES:To examine the assumption that amniotic fluid alpha-fetoprotein (AFAFP) levels are different in female and male twin fetuses. DESIGN:Amniotic fluid levels of AFP in pregnancies with female and male fetuses in gender-concordant and gender-discordant twins were compared. A t test of p < 0.05 was considered si...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000071015

    authors: Sharony R,Drugan A,Amiel A,Grinshpun-Cohen J,Markov S,Fejgin MD

    更新日期:2003-07-01 00:00:00

  • Neonatal leukemoid reaction and early development of bronchopulmonary dysplasia in a very low-birth-weight infant.

    abstract::The factors controlling the recruitment of inflammatory cells and the activation of the cytokine cascade in low-birth-weight premature infants have been implicated in the sequence of multiorgan inflammatory diseases, including the chronic lung disease of prematurity, bronchopulmonary dysplasia. This article describes ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000053900

    authors: Zanardo V,Magarotto M,Rosolen A

    更新日期:2001-05-01 00:00:00

  • A New Method to Measure the Subpubic Arch Angle Using 3-D Ultrasound.

    abstract:OBJECTIVES:The aim of this study was to assess the reproducibility of both a new contrast-enhancing technique (Oblique View eXtended Imaging, OVIX; Samsung) and the recently reported 3-D multiplanar technique (MPT) in the measurement of the subpubic angle (SPA) among a group of women at term gestation. In addition, we ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000380947

    authors: Ghi T,Youssef A,Martelli F,Montaguti E,Krsmanovic J,Pacella G,Pilu G,Rizzo N,Gabrielli S

    更新日期:2015-01-01 00:00:00

  • Brachial Artery Flow Mediated Dilation in the First Trimester to Predict the Occurrence of Hypertensive Disorders during Pregnancy.

    abstract:OBJECTIVES:To determine whether brachial artery flow-mediated dilation (FMD) assessed by ultrasonography during the late first trimester is able to predict the occurrence of hypertensive disorders during pregnancy. METHODS:Maternal endothelial function was assessed by flow-mediated dilation (FMD) of the brachial arter...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000366059

    authors: Alves JA,Miyague AH,de Sousa PC,Maia SB,Costa Fda S,Martins WP

    更新日期:2015-01-01 00:00:00

  • Fetoscopic endotracheal occlusion for severe isolated diaphragmatic hernia: initial experience from a single clinic in Brazil.

    abstract:OBJECTIVE:To report on the initial experience in a single Brazilian university clinic of the use of fetoscopic endotracheal occlusion (FETO) to treat severe isolated congenital diaphragmatic hernia (CDH). METHODS:The inclusion criteria for FETO for this prospective study were isolated CDH and intrathoracic herniation ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000314617

    authors: Peralta CF,Sbragia L,Bennini JR,de Fátima Assunção Braga A,Sampaio Rousselet M,Machado Rosa IR,Barini R

    更新日期:2011-01-01 00:00:00

  • Which stem cells should be used for transplantation?

    abstract::In view of the ever-increasing demand for human stem cells for transplantation, we initiated in vitro and in vivo studies of human fetal bone marrow stem/progenitor cells derived from lost pregnancies at 16-20 weeks. Utilizing non-human primates as models, we demonstrated that fetal tissue has distinctive biological a...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000074252

    authors: Michejda M

    更新日期:2004-01-01 00:00:00

  • Prenatal Prediction of the Type of Omphalocele Closure by Different Medical Consultants.

    abstract:INTRODUCTION:To evaluate differences between consultants of different disciplines in the prenatal prediction of the type of postnatal surgical closure of an omphalocele. MATERIAL AND METHODS:Twenty-one images of prenatally detected omphaloceles prior to 24 weeks of gestation were included. A standardized form provided...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000430439

    authors: Peters NC,Visser 't Hooft ME,Eggink AJ,Tibboel D,Ursem N,Wijnen RM,Bonsel GJ,Cohen-Overbeek TE

    更新日期:2016-01-01 00:00:00

  • Ehlers-Danlos type IV in pregnancy. A case report and a literature review.

    abstract:BACKGROUND:Ehlers-Danlos syndrome is a heterogeneous group of connective tissue disorders, characterized by a defect in the synthesis of collagen. The syndrome is subdivided into different clinical subtypes, the most hazardous of which is type IV, the vascular type. It can manifest itself in various complications such ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000109218

    authors: Erez Y,Ezra Y,Rojansky N

    更新日期:2008-01-01 00:00:00

  • Amniotic fluid index in low-risk, post-dates pregnancies.

    abstract:OBJECTIVE:To determine normal values for amniotic fluid index (AFI) in uncomplicated post-dates singleton pregnancies and compare it to current reference ranges. POPULATION:Four hundred and forty-eight women with singleton, uncomplicated pregnancies, presenting for post-dates assessment (gestation 40+0 to 42+0 weeks) ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000265554

    authors: Griffin M,Attilakos G,Greenwood R,Denbow M

    更新日期:2009-01-01 00:00:00