Does bipolar disorder have a benign course?

abstract：BACKGROUND:It is unclear how brain reserve interacts with gender and apolipoprotein E4 (APOE4) genotype, and how this influences the progression of Alzheimer's disease (AD). The association between intracranial volume (ICV) and progression to AD in subjects with mild cognitive impairment (MCI), and differences accordin...

journal_title：International psychogeriatrics

authors： An H,Son SJ,Cho S,Cho EY,Choi B,Kim SY,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2016-05-01 00:00:00

abstract：:ABSTRACTAssociations between high body mass index (BMI) and subsequent cognitive decline, reported in elderly averaging below age 75, become less consistent at older ages. We compared the associations of BMI with cognition in moderately old (ages 75-84, N = 154) and oldest-old (85+, N = 93) samples. BMI and cognition ...

journal_title：International psychogeriatrics

authors： Schmeidler J,Mastrogiacomo CN,Beeri MS,Rosendorff C,Silverman JM

更新日期：2019-06-01 00:00:00

abstract：:Most people who work in aged care have a fair idea of what is meant by cognitive impairment or decline, and we have some moderately robust instruments for detecting it and measuring change over time. Frailty is much more difficult to define, but like hard core pornography (Stewart, 1964), many of us "know it when we s...

journal_title：International psychogeriatrics

authors： Ames D

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative prevalence of symptom clusters in mild and moderate Alzheimer's disease (AD). METHODS:Confirmatory factor analysis (CFA) was performed on the polychoric correlation matrix of 12 NPI i...

journal_title：International psychogeriatrics

authors： Cheng ST,Kwok T,Lam LC

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Cognitive impairment and depression are common and disabling non-motor symptoms of Parkinson's disease (PD). Previous studies have shown associations between them but the nature of the relationship remains unclear. In chronic illness, problem- or task-oriented coping strategies are associated with better out...

journal_title：International psychogeriatrics

authors： Hurt CS,Landau S,Burn DJ,Hindle JV,Samuel M,Wilson K,Brown RG,PROMS-PD Study Group.

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Hospital-treated deliberate self harm and suicide among older adults have rarely been examined at a national level. METHODS:The Irish Central Statistics Office provided suicide and undetermined death data for 1980-2006. The National Registry of Deliberate Self Harm collected data relating to deliberate self...

journal_title：International psychogeriatrics

authors： Corcoran P,Reulbach U,Perry IJ,Arensman E

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Young-onset dementia (YOD) has a profound impact on spouses. However, little is known on how the quality of the relationship changes over time in YOD. This study aims to determine how the quality of the relationship changes over time and identify predictors of this change. METHODS:This study used data from ...

journal_title：International psychogeriatrics

authors： Bruinsma J,Peetoom K,Millenaar J,Köhler S,Bakker C,Koopmans R,Pijnenburg Y,Verhey F,de Vugt M

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:Capgras syndrome is characterized by the recurrent, transient belief that a person has been replaced by an identical imposter. We reviewed clinical characteristics of Dementia with Lewy Bodies (DLB) patients with Capgras syndrome compared to those without Capgras. METHODS:We identified 55 consecutive DLB pa...

journal_title：International psychogeriatrics

authors： Thaipisuttikul P,Lobach I,Zweig Y,Gurnani A,Galvin JE

更新日期：2013-05-01 00:00:00

abstract：:Although individuals aged 65 and over accounted for 12% of the total population of Japan in 1990, suicides in this age group consisted of 29% of all suicides. The elderly population of Japan is expected to grow rapidly to 24% of the total population by the year 2020, and suicide prevention for the elderly is an urgent...

journal_title：International psychogeriatrics

authors： Takahashi Y,Hirasawa H,Koyama K,Asakawa O,Kido M,Onose H,Udagawa M,Ishikawa Y,Uno M

更新日期：1995-07-01 00:00:00

abstract：:Many nursing home residents are candidates for antipsychotic pharmacotherapy for dementia-related behavioral disturbances that include physical agitation and aggression, verbal outbursts, anxiety, and depression. These patients are often resistant to or intolerant of standard neuroleptics and are usually receiving mul...

journal_title：International psychogeriatrics

authors： Goldberg RJ,Goldberg J

更新日期：1997-03-01 00:00:00

abstract：:ABSTRACT Background: The association between disability and depression is complex, with disability well established as a correlate and consequence of late life depression. Studies in community samples report that greater volumes of cerebral white matter hyperintensities (WMHs) seen on brain imaging are linked with fun...

journal_title：International psychogeriatrics

authors： Hybels CF,Pieper CF,Landerman LR,Payne ME,Steffens DC

更新日期：2014-05-09 00:00:00

abstract：BACKGROUND:There is a paucity of simulation-based dementia education programmes for acute care settings that support the development of interpersonal skills pertinent to good care. Moreover, few studies measure the effectiveness of such programmes by evaluating the persistence of practice change beyond the immediate ti...

journal_title：International psychogeriatrics

authors： Heward M,Board M,Spriggs A,Murphy J

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine levels, rates and progression of apathy in healthy older persons and to investigate factors associated with its progression. METHODS:Seventy-six healthy elderly subjects, aged 58-85 years (mean 69.9), who were recruited by general advertisement and through local commun...

journal_title：International psychogeriatrics

authors： Brodaty H,Altendorf A,Withall A,Sachdev P

更新日期：2010-05-01 00:00:00

abstract：:Understanding of vascular substrates of cognitive decline in the elderly is evolving to include a major emphasis on the impact of small vessel disease (SVD). While existing concepts of multi-infarct dementia and strategic infarct dementia remain valid, they present difficulty in generalizing clinicopathological correl...

journal_title：International psychogeriatrics

authors： Ince PG,Fernando MS

更新日期：2003-01-01 00:00:00

abstract：:Few instruments are available with which to measure behavioral and psychological signs and symptoms in Hispanic patients with dementia. Therefore, the aim of the current study was to develop and evaluate a 17-item scale adapted from the Revised Memory and Behavior Problems Checklist. This measure, the Behavior Problem...

journal_title：International psychogeriatrics

authors： Harwood DG,Barker WW,Ownby RL,Bravo M,Aguero H,Duara R

更新日期：2001-03-01 00:00:00

abstract：:There is no doubt that family carers who look after a family member with dementia or with a functional mental illness fulfill an important role, not only for their loved one, but also for the health and aged care systems of the countries they live in. Due to increasing life expectancy, but also improved healthcare the...

journal_title：International psychogeriatrics

authors： Lautenschlager NT,Diehl-Schmid J,Loi SM,Mayer J,Tensil M,Kurz AF

更新日期：2017-12-01 00:00:00

abstract：:The role of the physician is critical in the evaluation of cognitively impaired patients for two reasons: (a) The longitudinal relationship between the patient and physician provides a unique opportunity to observe changes over time, generating confidence that may encourage the patient and family to report any concern...

journal_title：International psychogeriatrics

authors： Finkel SI,Woodson C

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Children of patients with young onset dementia (YOD) who are confronted with a parent who has a progressive disease, often assist in caregiving tasks, which may have a great impact on their lives. The objective of the present study is to explore the experiences of children living with a young parent with dem...

journal_title：International psychogeriatrics

authors： Millenaar JK,van Vliet D,Bakker C,Vernooij-Dassen MJ,Koopmans RT,Verhey FR,de Vugt ME

更新日期：2014-12-01 00:00:00

abstract：:ABSTRACTBackground:Cognition is multidimensional, and each domain plays a unique and crucial part in successful daily life engagement. However, less attention has been paid to multi-domain cognitive health for the elderly, and the role of lifestyle factors in each domain remains unclear. METHODS:We conducted a cross-...

journal_title：International psychogeriatrics

authors： Yuan M,Chen J,Han Y,Wei X,Ye Z,Zhang L,Hong YA,Fang Y

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Multifactorial strategies that prevent or delay the onset or progress of cognitive decline and dementia are needed, and should include education regarding recognized risk factors. The current study sought to investigate whether older adults "at risk" of cognitive decline benefit from psychoeducation targetin...

journal_title：International psychogeriatrics

authors： Norrie LM,Diamond K,Hickie IB,Rogers NL,Fearns S,Naismith SL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Research on the behavioral correlates of anxiety in older adults is sparse. The aim of this study was to explore the association of anxiety with behavioral patterns defined by health, activity, emotional and social variables. METHODS:A convenience sample of 395 older adults completed measures of health, act...

journal_title：International psychogeriatrics

authors： Losada A,Márquez-González M,Pachana NA,Wetherell JL,Fernández-Fernández V,Nogales-González C,Ruiz-Díaz M

更新日期：2015-07-01 00:00:00

abstract：:Observed cognitive decline in the elderly has been widely reported in the literature. The relation of experimental cognitive ability measures to real-world cognitive competence has been questioned. This research examines the validity of English-language versions of two measures of everyday competency: the Memory in Re...

journal_title：International psychogeriatrics

authors： Goodman CR,Zarit SH

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:This review presents an overview of the published literature on the effectiveness of continuing professional education (CPE), which includes continuing medical education (CME) of different health care professionals in healthcare settings, for improving patient management and patient outcomes. This review sum...

journal_title：International psychogeriatrics

authors： Rampatige R,Dunt D,Doyle C,Day S,van Dort P

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Studies generally describe the relationship between physical fitness and cognitive function by measuring only one or two specific cognitive tasks. In addition, in spite of the significant increase in life expectancy, the age of participants in these studies does not extend beyond a mean age of 70 years. This...

journal_title：International psychogeriatrics

authors： Netz Y,Dwolatzky T,Zinker Y,Argov E,Agmon R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The orbitofrontal cortex has been implicated as a key component in depression by several imaging studies. This study aims to examine morphometrically glial cell and neuronal density and neuronal volume in the orbitofrontal cortex of late-life major depression patients. METHODS:Post mortem tissue from 13 pat...

journal_title：International psychogeriatrics

authors： Khundakar A,Morris C,Oakley A,Thomas AJ

更新日期：2011-02-01 00:00:00

abstract：:This paper presents updated analyses on the genetic associations of sleep disruption in individuals with Alzheimer's disease (AD). We published previously a study of the association between single nucleotide polymorphisms (SNPs) found in eight genes related to circadian rhythms and objective measures of sleep-wake dis...

journal_title：International psychogeriatrics

authors： Yesavage JA,Noda A,Heath A,McNerney MW,Domingue BW,Hernandez Y,Benson G,Hallmayer J,O'Hara R,Williams LM,Goldstein-Piekarski AN,Zeitzer JM,Fairchild JK

更新日期：2020-07-01 00:00:00

abstract：:Major depression in the elderly is often a relapsing, chronic illness with high risk for chronic invalidism, poor treatment compliance, and suicide. In most cases, maintenance treatment to prevent recurrence and to enhance the quality of life is thought to be indicated. We review recent data from our ongoing studies t...

journal_title：International psychogeriatrics

authors： Reynolds CF 3rd,Frank E,Perel JM,Mazumdar S,Kupfer DJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Subjective memory complaints (SMCs) are a common occurrence for adults, which increase with age, and cause considerable distress. Traditionally SMCs have been assessed by either questionnaires, which ask whether a person has experienced given examples of SMCs, or open-ended questions which elicit spontaneous...

journal_title：International psychogeriatrics

authors： Burmester B,Leathem J,Merrick P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The ability to manage everyday technology (ET), such as computers and microwave ovens, is increasingly required in the performance of everyday activities and participation in society. This study aimed to identify aspects that influence the ability to manage ET among older adults with and without cognitive im...

journal_title：International psychogeriatrics

authors： Malinowsky C,Almkvist O,Nygård L,Kottorp A

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To investigate the presence of neuropsychiatric symptoms (NPS) and sub-syndromes in elderly community-dwelling Asians with varying severity of cognitive impairment. METHODS:Chinese and Malay participants (n = 613) from the Epidemiology of Dementia in Singapore (EDIS) Study aged ≥ 60 years underwent clinical...

journal_title：International psychogeriatrics

authors： Xu X,Ang SL,Hilal S,Chan QL,Wong TY,Venketasubramanian N,Ikram MK,Chen CL

更新日期：2015-11-01 00:00:00