Abstract:
:The objective of this systematic review and meta-analysis was to evaluate the efficacy and safety of i.v. tranexamic acid (TXA) in simultaneous bilateral total knee arthroplasty (TKA). Potentially relevant published reports were identified from the following electronic databases: Medline, PubMed, Embase, ScienceDirect and Cochrane Library. RevMan v5.3was used to pool data. Two randomized controlled trials and four case-control studies met the inclusion criteria. The current meta-analysis identified significant differences between TXA group and control groups in terms of postoperative hemoglobin concentration (P < 0.01), drainage volume (P < 0.01), transfusion rate (P < 0.01) and units transfused (P = 0.006). There were no significant differences in length of stay (P = 0.66), operation time (P = 0.81) or and incidence of adverse effects such as infection (P = 0.42), deep venous thrombosis (DVT) (P = 0.88) and pulmonary embolism (PE) (P = 0.11). Our results show that i.v. administration of TXA in simultaneous bilateral TKA reduces postoperative drops in hemoglobin concentration, drainage volume, and transfusion requirements and does not prolong length of stay or operation time. Moreover, no adverse effects, such as infection, DVT or PE, were associated with TXA.
journal_name
Orthop Surgjournal_title
Orthopaedic surgeryauthors
Jiang X,Ma XL,Ma JXdoi
10.1111/os.12256subject
Has Abstractpub_date
2016-08-01 00:00:00pages
285-93issue
3eissn
1757-7853issn
1757-7861journal_volume
8pub_type
杂志文章,meta分析,评审abstract:OBJECTIVE:To study the clinical features and diagnosis of bursal-side partial-thickness rotator cuff tears. METHODS:From August 1999 to June 2006, 38 patients with bursal-side partial-thickness rotator cuff tear were evaluated. Twenty-eight men and ten women of average age 45.7 years (range, 18-69 years) with 11 left ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2010.00097.x
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the bi-planar robot navigation system for insertion of cannulated screws in femoral neck fractures. METHOD:Between January 2016 and December 2016, 60 patients with femoral neck fractures were separately treated using percutaneous cannulated screws assisted by the bi-planar robot navigation system...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12450
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To analyze the approach and feasibility of one-stage anterior release and reduction with posterior fusion for irreducible atlantoaxial dislocation. METHODS:Ten male and 6 female patients, with an average age of 36 years, including 13 patients with old trauma, 2 with rheumatoid disease, and 1 with os odontoid...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2009.00049.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To assess the difference between drainage and non-drainage after total hip arthroplasty (THA) in Chinese subjects by evaluating post-operative complications and joint function. METHODS:One hundred and sixty-eight patients undergoing THA were randomly allocated into drainage (83 patients) and non-drainage gro...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/os.12092
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Acute hematogenous infection is a devastating complication that can occur after total knee arthroplasty (TKA). The best strategies for management of this infection remain controversial. Two-stage revision has been well described as the gold standard for the management of chronic late infections. However, ther...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12297
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical effect of the minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation using a tubular retractor in the management of degenerative lumbar disease. METHODS:A retrospective analysis was conducted to analyze the clinical outco...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12345
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of surgery and rehabilitation on patients undergoing total knee arthroplasty (TKA). METHODS:Twelve patients and 12 healthy controls were enrolled and their clinical scores evaluated by a doctor. Gait data, including walking velocity, stride length, single support time, foot fall and s...
journal_title:Orthopaedic surgery
pub_type: 临床试验,杂志文章
doi:10.1111/os.12270
更新日期:2016-08-01 00:00:00
abstract::Atlantoaxial transarticular facet screw fixation (Magerl technique) and C1 lateral mass screws combined with C2 pedicle screws fixation (Harms technique) are the most commonly used techniques for posterior internal fixation in the upper cervical spine. Upper cervical spinal surgery is a technically demanding and chall...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,实务指引
doi:10.1111/os.12454
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:A series of constant anatomical structures were used as guide targets for screw placement to improve the accuracy of cortical screw placement and reduce surgical injury and fluoroscopy radiation. The most commonly used angles and distances between the cortical bone screw insertion point and the lateral margi...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12775
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy and safety of tranexamic acid (TXA) in the reduction of bleeding and the need for transfusion in elderly intertrochanteric fracture patients. METHODS:A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group i...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/os.12511
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:Giant cell tumors of bone (GCTs) are bone destructive neoplasms, the bone resorption being mediated by osteoclasts. Given that microRNAs are crucially involved in tumorigenesis and the modulation of cell fate and behavior, they are promising candidates for regulation of osteoclastogenesis. However, no reliabl...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12231
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:To determine whether the rates of postoperative complications, rate of readmission, cumulative transfusion volume, and length of stay (LOS) differ between simultaneous total hip arthroplasty (THA) and staged bilateral THA and to assess whether the length of the interval between staged procedures influences s...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12617
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To describe the technique and analyze the outcomes of joint-preserving surgical treatments which included anatomical reconstruction or alignment correction for talar malunions or nonunions, and avoid development of degenerative changes in the adjacent joints. METHODS:Eight patients who had painful talar malu...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12301
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To investigate the compensatory mechanism of maintaining the sagittal balance in degenerative lumbar scoliosis patients with different pelvic incidence (PI). METHODS:This was a retrospective imaging observation study. Patients in our department with degenerative lumbar scoliosis between 2017 and 2019 were re...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12805
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:The prevention and treatment of the common complication of cerebrospinal fluid leakage (CSFL) during anterior approach cervical spine surgery for severe ossification of the posterior longitudinal ligament (OPLL) is documented. METHOD:A retrospective analysis of 47 patients with severe cervical OPLL aged 39 t...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12007
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To investigate the biological functions of long noncoding RNA-H19 (H19) in the pathogenesis of disuse osteoporosis (DOP). METHODS:Fifty-four male Sprague Dawley (SD) rats were randomly divided into three groups: baseline control (BC, 6), age-matched control (AC, 24), and hindlimb unloading (HLU, 24). The rat...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12321
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To examine the results of an anular closure device for prevention of lumbar disc reherniation in daily routine practice. METHODS:Fifty patients with large anular defects were treated with limited discectomy and a bone-anchored anular closure device. The device physically occludes the defect in the anulus fib...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12495
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:"Lisfranc joint injury" is comprised of a tarsometatarsal joint-complex injury. The Lisfranc complex injury is always a challenge for orthopedists, and the optimum treatment is still up for debate. Anatomic reduction and stable internal fixation prove to have no satisfactory outcomes. This research aims to co...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12316
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To investigate delay in diagnosis by both patients and doctors, and to evaluate its effect on outcomes of high-grade sarcoma of bone in a single-referral oncological center. METHODS:Fifty-four patients with osteosarcoma, 29 with Ewing sarcoma and 19 with chondrosarcoma were enrolled in this retrospective stu...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12239
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To investigate the outcomes of total knee arthroplasty (TKA) in patients with a prior femoral or tibial fracture, and identify the risk factors for surgical site complications and reoperations. METHODS:Seventy-one TKAs performed in 71 patients with a prior tibial or femoral fracture between January 2005 and ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12610
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the results of treatment of osteonecrosis of the femoral head by structural augmentation through a routine core decompression procedure combined with insertion of cannulated bone screws incorporating autogenous bone graft and biomaterial containing decalcified bone matrix. METHODS:From February 2...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2008.00008.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To quantitatively describe the stress of the ligamentum flavum (LF) using the finite element method and to compare the stress at different parts of the healthy LF. METHODS:Based on the high resolution computed tomography imaging data of a healthy 22-year-old man, three-dimensional nonlinear L4-5 lumbar finit...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12675
更新日期:2020-06-01 00:00:00
abstract::Because current therapies have not always been successful and effective, the possibility of regenerating the nucleus pulposus (NP) through a tissue-engineered construct offers a novel therapeutic possibility for symptomatic degenerative disc diseases (DDDs). However, more research is necessary to identify the optimal ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12020
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Knee arthroscopy is a commonly performed orthopedic procedure. Post-operatively, adequate pain relief reduces the surgical stress response and patient's morbidity and facilitates rehabilitation. The analgesic effect of dexmedetomidine (2 μg/kg body weight) as an adjunct to ropivacaine in knee arthroscopic kne...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/os.12182
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the mid-term outcomes of transoral atlantoaxial reduction plate (TARP) internal fixation for the treatment of irreducible atlantoaxial dislocation. METHODS:From April 2003 to April 2005, 31 patients with irreducible atlantoaxial dislocation were treated with TARP internal fixation. The average ag...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2010.00077.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To assess the clinical efficacy of mini-invasive transforaminal lumbar interbody fusion (TLIF) through the Wiltse approach for treating lumbar spondylolytic spondylolisthesis. METHODS:In this retrospective controlled study, 69 cases with lumbar spondylolytic spondylolisthesis treated in Qilu hospital from Ap...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/os.12224
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To retrospectively investigate the experience at one urban level one trauma center with gunshot femoral fractures with vascular injury and to examine the implication of surgical sequence with regards to short-term complications and ischaemia time. METHODS:We performed a retrospective study of 24 patients tre...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2012.00186.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:The present retrospective study was performed to assess the anatomical features of the pedicle in isthmic spondylolisthesis and to correlate this with degree of slip. METHODS:Twenty-six patients with isthmic spondylolytic spondylolisthesis were studied. Relevant patient variables, length, width, height of th...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12173
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:Occipitocervical fusion (OCF) is an effective treatment for instability of occipitocervical junction (OCJ). The occipital condyle screw serves as a novel surgical technique for occipitocervical fixation. However, the intraoperative procedures for the occipital condyle screw technique have relied on surgeons'...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12700
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of hip replacement and intramedullary nails for treating unstable intertrochanteric fractures in elderly patients. METHODS:Randomized clinical trials (RCTs) to compare hip replacement with intramedullary nail in the management of elderly patients with unstable intertrochan...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,meta分析
doi:10.1111/os.12532
更新日期:2019-10-01 00:00:00