Report of the 4th European Zebrafish Principal Investigator Meeting.

abstract：:The genetic compensation response (GCR), triggered by deleterious mutations but not by gene knockdown, has been proposed to explain many phenotypic discrepancies between gene-knockout and gene-knockdown models. GCRs have been observed in many model organisms from mice to Arabidopsis. Although the GCR is beneficial for...

journal_title：Zebrafish

authors： Ma Z,Chen J

更新日期：2020-05-20 00:00:00

abstract：:A husbandry workshop on July 3, 2017, at the 10th European Zebrafish Meeting in Budapest, Hungary (July 3-July 7, 2017), focused on the standardization, optimization, and streamlining of fish facility procedures. Standardization can be achieved for example by developing novel software and hardware tools, such as a fis...

journal_title：Zebrafish

authors： Oltová J,Barton C,Certal AC,Argenton F,Varga ZM

更新日期：2018-04-01 00:00:00

abstract：:The second European Zebrafish Principal Investigator (PI) Meeting was held in March, 2012, in Karlsruhe, Germany. It brought together PIs from all over Europe who work with fish models such as zebrafish and medaka to discuss their latest results, as well as to resolve strategic issues faced by this research community....

journal_title：Zebrafish

authors： Cavodeassi F,Del Bene F,Fürthauer M,Grabher C,Herzog W,Lehtonen S,Linker C,Mercader N,Mikut R,Norton W,Strähle U,Tiso N,Foulkes NS

更新日期：2013-03-01 00:00:00

abstract：:The zebrafish system has been established as a useful model for the study of carcinogenesis. The cytogenetic characterization of the genome is vital for furthering our understanding of the progression of the disease. Establishing a basic description of the zebrafish chromosomal karyotype and markers for each specific ...

journal_title：Zebrafish

authors： Peterson SM,Freeman JL

更新日期：2009-12-01 00:00:00

abstract：:β-Cells of the islet of Langerhans produce insulin to maintain glucose homeostasis. Self-replication of β-cells is the predominant mode of postnatal β-cell production in mammals, with about 20% of rodent β cells dividing in a 24-hour period. However, replicating β-cells are rare in adults. Induction of self-replicatio...

journal_title：Zebrafish

authors： Li M,Maddison LA,Crees Z,Chen W

更新日期：2013-06-01 00:00:00

abstract：:Electronic databases provide effective and efficient management of zebrafish colony operations, but commercially available options are expensive. In this study we have developed a free zebrafish management repository alternative using free Google applications. Husbandry information is logged into a Google Sheets-based...

journal_title：Zebrafish

authors： LaCoursiere CM,Ullmann JFP,Poduri A

更新日期：2018-12-01 00:00:00

abstract：:Traditional working heart preparations, based on the original Langendorff setup, are widely used experimental models that have tremendously advanced the cardiovascular field. However, these systems can be deceivingly complex, requiring the maintenance of pH with CO(2), the delivery of oxygenated perfusate, and the nee...

journal_title：Zebrafish

authors： Hecker L,Khait L,Sessions SK,Birla RK

更新日期：2008-12-01 00:00:00

abstract：:One of the strengths of the zebrafish is the ease with which in situ hybridization can be performed to determine spatial and temporal patterns of gene expression in whole embryos. Thus far, colorimetric detection methods are mainly used for these analyses. Here we describe a fluorescent in situ hybridization (FISH) pr...

journal_title：Zebrafish

authors： Clay H,Ramakrishnan L

更新日期：2005-01-01 00:00:00

abstract：:Many facilities house fish in separate static containers post-procedure, for example, while awaiting genotyping results. This ensures fish can be easily identified, but it does not allow for provision of continuous filtered water or diet. At the Wellcome Trust Sanger Institute, concern over the housing conditions led ...

journal_title：Zebrafish

authors： Goodwin N,Westall L,Karp NA,Hazlehurst D,Kovacs C,Keeble R,Thompson P,Collins R,Bussell J

更新日期：2016-07-01 00:00:00

abstract：:The zebrafish, Danio rerio, has emerged as a major model organism for biomedical research, yet little is known about its natural history. We review the literature pertaining to the geographic range, biotic and abiotic habitats, and life cycle of the zebrafish. We also report our own field study to document several asp...

journal_title：Zebrafish

authors： Engeszer RE,Patterson LB,Rao AA,Parichy DM

更新日期：2007-04-01 00:00:00

abstract：:Comprising a large number of species, the genus Astyanax has been intensively studied by several approaches to elucidate its evolutionary relationships. Such studies have demonstrated that many nominal species are artificial clusters where distinct taxa are grouped under the same denomination. Astyanax aff. fasciatus ...

journal_title：Zebrafish

authors： Kavalco KF,Pazza R,Brandão Kde O,Garcia C,Bertollo LA,de Almeida-Toledo LF

更新日期：2016-08-01 00:00:00

abstract：:After its introduction for scientific investigation in the 1950s, the cypriniform zebrafish, Danio rerio, has become a valuable model for the study of regenerative processes and mechanisms. Zebrafish exhibit epimorphic regeneration, in which a nondifferentiated cell mass formed after amputation is able to fully regene...

journal_title：Zebrafish

authors： Lebedeva L,Zhumabayeva B,Gebauer T,Kisselev I,Aitasheva Z

更新日期：2020-12-01 00:00:00

abstract：:Our first Zebrafish Enhancer TRAP lines database (ZETRAP) generated a few years ago was a web-based system informing the scientific community about the developmental, genetic, and genomic aspects of transgenic zebrafish lines expressing the cytosolic version of EGFP. These transgenic lines were obtained in a primary s...

journal_title：Zebrafish

authors： Kondrychyn I,Teh C,Garcia-Lecea M,Guan Y,Kang A,Korzh V

更新日期：2011-12-01 00:00:00

abstract：:In an effort to engage students in original research while teaching them basic molecular biology skills, we have designed a course for upper level undergraduate students and beginning graduate students that employs in situ hybridization in whole-mount zebrafish embryos to explore the concept of differential gene regul...

journal_title：Zebrafish

authors： Schmoldt A,Forecki J,Hammond DR,Udvadia AJ

更新日期：2009-06-01 00:00:00

abstract：:Pamela Raymond received her B.S., M.S., and Ph.D. degrees from the University of Michigan. She is currently Professor of Molecular, Cellular, and Developmental Biology in the College of Literature, Science, and the Arts at the University of Michigan. She has held academic appointments at Harvard Medical School and the...

journal_title：Zebrafish

authors： Raymond P

更新日期：2005-01-01 00:00:00

abstract：:Many assays are used in animal model systems to measure specific human disease-related behaviors. The use of both adult and larval zebrafish as a behavioral model is gaining popularity. As this work progresses and potentially translates into new treatments, we must do our best to improve the sensitivity of these assay...

journal_title：Zebrafish

authors： Philpott C,Donack CJ,Cousin MA,Pierret C

更新日期：2012-12-01 00:00:00

abstract：:This project was developed to promote understanding of how mathematics and statistical analysis are used as tools in genetic research. It gives students the opportunity to carry out hypothesis-driven experiments in the classroom: students generate hypotheses about Mendelian and non-Mendelian inheritance patterns, gath...

journal_title：Zebrafish

authors： Lindemann S,Senkler J,Auchter E,Liang JO

更新日期：2011-06-01 00:00:00

abstract：:A study was conducted to preliminarily assess the contribution of the intestinal microflora to biotin supply in zebrafish. Biotin and avidin were added to three isonitrogenous and isocaloric purified diets to provide molar avidin: biotin ratios of 0:0 (basal diet), 0:1 (biotin-supplemented diet), and 120:0. Another di...

journal_title：Zebrafish

authors： Yossa R,Sarker PK,Vandenberg GW

更新日期：2011-12-01 00:00:00

abstract：:An emergent field of animal personality necessitates a method for repeated high-throughput quantification of behavioral traits across contexts. In this study, we have developed an automated video stimulus approach to sequentially present different contexts relevant to five "personality" traits (exploration, boldness, ...

journal_title：Zebrafish

authors： Fangmeier ML,Noble DWA,O'Dea RE,Usui T,Lagisz M,Hesselson D,Nakagawa S

更新日期：2018-04-01 00:00:00

abstract：:Analysis of genes compromising the glomerular filtration barrier in rodent models using transgenic or knockdown approaches is time- and resource-consuming and often leads to unsatisfactory results. Therefore, it would be beneficial to have a selection tool indicating that your gene of interest is in fact associated wi...

journal_title：Zebrafish

authors： Hanke N,King BL,Vaske B,Haller H,Schiffer M

更新日期：2015-10-01 00:00:00

abstract：:Dr. Zhiyuan Gong is Associate Professor in the Department of Biological Sciences, National University of Singapore. He graduated with a B.Sc. degree in marine biology from Ocean University of China and received his Ph.D. degree in developmental biology from McGill University in Canada. He spent many years at the Unive...

journal_title：Zebrafish

authors： Gong Z

更新日期：2004-01-01 00:00:00

abstract：:We have developed a simple method for the induction of cataracts in adult zebrafish using hydrogen peroxide. Our method uses a corneal puncture followed by intraocular injection of hydrogen peroxide into the anterior chamber. The procedure can be done rapidly, forming a highly opaque cataract almost immediately, and f...

journal_title：Zebrafish

authors： Prior HM,Letwin K,Tuininga A,Nguyen M

更新日期：2018-04-01 00:00:00

abstract：:To promote application of the fruits of zebrafish research, we need to cultivate understanding of the use of zebrafish not only in the research community but also among the general public. On Open Days at our institute, the National Institute for Environmental Studies (NIES), our zebrafish group exhibits our research ...

journal_title：Zebrafish

authors： Aoki Y

更新日期：2009-06-01 00:00:00

abstract：:Most young researchers leaving the safe haven of postdoctoral life for the unchartered territory of a PI position are confronted with a multitude of new tasks. For those using fish as their favorite model system, this often includes the daunting task of setting up and running a fish facility. New PIs are expected to k...

journal_title：Zebrafish

authors： McNabb A,Scott K,Ochsenstein Ev,Seufert K,Carl M

更新日期：2012-09-01 00:00:00

abstract：:Studies on parental aging are a very attractive field, although it is poorly understood how parental age affects embryonic development and adult traits of the offspring. In this study, we used the turquoise killifish Nothobranchius furzeri, as is the vertebrate with shortest captive lifespan and an interesting model. ...

journal_title：Zebrafish

authors： Api M,Biondi P,Olivotto I,Terzibasi E,Cellerino A,Carnevali O

更新日期：2018-04-01 00:00:00

abstract：:Dimethyl sulfoxide (DMSO), a widely used carrier solvent, can be toxic to test organisms and has species-specific sensitivity. In this study, the developmental toxicity and stress protein responses of DMSO to rare minnow (Gobiocypris rarus) and zebrafish (Danio rerio) with two tests were compared in the early life sta...

journal_title：Zebrafish

authors： Xiong X,Luo S,Wu B,Wang J

更新日期：2017-02-01 00:00:00

abstract：:By means of scientometric indicators, this study investigated the characteristics of scientific production and research collaboration involving zebrafish (Danio rerio) in Brazilian Science indexed by the Web of Science (WoS). Citation data were collected from the WoS and data regarding Impact Factor (IF) were gathered...

journal_title：Zebrafish

authors： Gheno EM,Rosemberg DB,Souza DO,Calabró L

更新日期：2016-06-01 00:00:00

abstract：:The zebrafish has considerable potential for use as a model in the study of behavior in social systems, particularly dominance hierarchies, which are widespread in nature and can affect the lifelong success of individuals. There is, however, a paucity of information relating to the characterization of social groups an...

journal_title：Zebrafish

authors： Paull GC,Filby AL,Giddins HG,Coe TS,Hamilton PB,Tyler CR

更新日期：2010-03-01 00:00:00

abstract：:Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and behavioral research. Physiological similarity to mammals, ease of genetic manipulations, sensitivity to pharmacological and genetic factors, robust behavior, low cost, and potential for high-throughput screening contribute to the ...

journal_title：Zebrafish

authors： Kalueff AV,Gebhardt M,Stewart AM,Cachat JM,Brimmer M,Chawla JS,Craddock C,Kyzar EJ,Roth A,Landsman S,Gaikwad S,Robinson K,Baatrup E,Tierney K,Shamchuk A,Norton W,Miller N,Nicolson T,Braubach O,Gilman CP,Pittman J

更新日期：2013-03-01 00:00:00

abstract：:There is now strong evidence that early nutrition plays an important role in shaping later physiology. We assessed here whether soy protein concentrate (SPC) or soybean meal (SBM) in early diet would modify zebrafish responses to these products in later life. We fed zebrafish larvae with SPC-, SBM-, or a control-diet ...

journal_title：Zebrafish

authors： Perera E,Yúfera M

更新日期：2016-02-01 00:00:00