The effect of exercise hypertrophy and disuse atrophy on muscle contractile properties: a mechanomyographic analysis.

Abstract:

PURPOSE:To determine whether mechanomyographic (MMG) determined contractile properties of the biceps brachii change during exercise-induced hypertrophy and subsequent disuse atrophy. METHODS:Healthy subjects (mean ± SD, 23.7 ± 2.6 years, BMI 21.8 ± 2.4, n = 19) performed unilateral biceps curls (9 sets × 12 repetitions, 5 sessions per week) for 8 weeks (hypertrophic phase) before ceasing exercise (atrophic phase) for the following 8 weeks (non-dominant limb; treatment, dominant limb; control). MMG measures of muscle contractile properties (contraction time; T c, maximum displacement; D max, contraction velocity; V c), electromyographic (EMG) measures of muscle fatigue (median power frequency; MPF), strength measures (maximum voluntary contraction; MVC) and measures of muscle thickness (ultrasound) were obtained. RESULTS:Two-way repeated measures ANOVA showed significant differences (P < 0.05) between treatment and control limbs. During the hypertrophic phase treatment MVC initially declined (weeks 1-3), due to fatigue (decline in MPF), followed by improvement against control during weeks 6-8. Between weeks 5 and 8 treatment, muscle thickness was greater than control, reflecting gross hypertrophy. MMG variables Dmax (weeks 2, 7) and Vc (weeks 7, 8) declined. During the atrophic phase, MVC (weeks 9-12) and muscle thickness (weeks 9, 10) initially remained high before declining to control levels, reflecting gross atrophy. MMG variables D max (weeks 9, 14) and V c (weeks 9, 14, 15) also declined during the atrophic phase. No change in T c was found throughout the hypertrophic or atrophic phases. CONCLUSIONS:MMG detects changes in contractile properties during stages of exercise-induced hypertrophy and disuse atrophy suggesting its applicability as a clinical tool in musculoskeletal rehabilitation.

journal_name

Eur J Appl Physiol

authors

Than C,Tosovic D,Seidl L,Mark Brown J

doi

10.1007/s00421-016-3469-9

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

2155-2165

issue

11-12

eissn

1439-6319

issn

1439-6327

pii

10.1007/s00421-016-3469-9

journal_volume

116

pub_type

临床试验,杂志文章
  • An integrated view on the oxygenation responses to incremental exercise at the brain, the locomotor and respiratory muscles.

    abstract::In the past two decades oxygenation responses to incremental ramp exercise, measured non-invasively by means of near-infrared spectroscopy at different locations in the body, have advanced the insights on the underpinning mechanisms of the whole-body pulmonary oxygen uptake ([Formula: see text]) response. In healthy s...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00421-016-3468-x

    authors: Boone J,Vandekerckhove K,Coomans I,Prieur F,Bourgois JG

    更新日期:2016-12-01 00:00:00

  • Determinants, analysis and interpretation of the muscle compound action potential (M wave) in humans: implications for the study of muscle fatigue.

    abstract::The compound muscle action potential (M wave) has been commonly used to assess the peripheral properties of the neuromuscular system. More specifically, changes in the M-wave features are used to examine alterations in neuromuscular propagation that can occur during fatiguing contractions. The utility of the M wave is...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00421-017-3788-5

    authors: Rodriguez-Falces J,Place N

    更新日期:2018-03-01 00:00:00

  • Effects on dogs of surface-induced hypothermia and rewarming on the right heart function and pulmonary circulation.

    abstract::Hypothermia is commonly found in accidents on land and at sea, yet its pulmonary circulatory effects have not been studied before. To study the effects of hypothermia on the right heart function and pulmonary circulation, cardiac catheterization was carried out on nine anaesthetized beagle dogs. The dogs were cooled b...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s004210050059

    authors: Palo M,Lauri T,Timisjärvi J

    更新日期:2000-03-01 00:00:00

  • Two methods for determining plasma IL-6 in humans at rest and following exercise.

    abstract::We compared two methods to determine IL-6 at rest and following exercise. On two occasions, plasma IL-6 was determined in 10 men and 13 women before and immediately following 90 min of cycling at 65% V(O)(2max) using a cytometric bead array (CBA) and an ELISA. The CBA detected IL-6 in 63% of pre-exercise samples and 8...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-008-0866-8

    authors: Timmons BW,Hamadeh MJ,Tarnopolsky MA

    更新日期:2009-01-01 00:00:00

  • Influence of the world's most challenging mountain ultra-marathon on energy cost and running mechanics.

    abstract:PURPOSE:To examine the effects of the world's most challenging mountain ultra-marathon (Tor des Géants(®) 2012) on the energy cost of three types of locomotion (cycling, level and uphill running) and running kinematics. METHODS:Before (pre-) and immediately after (post-) the competition, a group of ten male experience...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-014-2824-y

    authors: Vernillo G,Savoldelli A,Zignoli A,Trabucchi P,Pellegrini B,Millet GP,Schena F

    更新日期:2014-05-01 00:00:00

  • Effects of mild-exercise training cessation in human skeletal muscle.

    abstract::Stoppage of endurance exercise training leads to complete loss of maximal oxygen uptake ([Formula: see text]) gain but not submaximal exercise blood lactate concentrations. However, the detailed mechanisms are still unknown. Thus, we investigated the effects of exercise-training cessation at lactate threshold (LT) int...

    journal_title:European journal of applied physiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00421-011-2036-7

    authors: St-Amand J,Yoshioka M,Nishida Y,Tobina T,Shono N,Tanaka H

    更新日期:2012-03-01 00:00:00

  • Estimation of maximal heart rate in recreational football: a field study.

    abstract:PURPOSE:To examine the accuracy of practical indirect methods (i.e., recreational football match and estimation equations) in assessing individual maximal heart rate (HRmax) in recreational football players. Sixty-two untrained male participants engaged in a recreational football intervention (age 39.3 ± 5.8 years, VO2...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-020-04334-4

    authors: Póvoas S,Krustrup P,Castagna C

    更新日期:2020-04-01 00:00:00

  • Acute hyperketonaemia alters T-cell-related cytokine gene expression within stimulated peripheral blood mononuclear cells following prolonged exercise.

    abstract:PURPOSE:We investigated the effect of the racemic β-hydroxybutyrate precursor, R,S-1,3-butanediol (BD), on T-cell-related cytokine gene expression within stimulated peripheral blood mononuclear cells (PBMC) following prolonged, strenuous exercise. METHODS:A repeated-measures, randomised, crossover study was conducted ...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00421-019-04263-x

    authors: Shaw DM,Merien F,Braakhuis A,Keaney L,Dulson DK

    更新日期:2020-01-01 00:00:00

  • Water immersion methods do not alter muscle damage and inflammation biomarkers after high-intensity sprinting and jumping exercise.

    abstract:PURPOSE:The aim of this study was to compare the efficacy of three water immersion interventions performed after active recovery compared to active recovery only on the resolution of inflammation and markers of muscle damage post-exercise. METHODS:Nine physically active men (n = 9; age 20‒35 years) performed an intens...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-020-04481-8

    authors: Ahokas EK,Kyröläinen H,Mero AA,Walker S,Hanstock HG,Ihalainen JK

    更新日期:2020-12-01 00:00:00

  • The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching.

    abstract::To determine the effects of creatine supplementation during short-term resistance training overreaching on performance, body composition, and resting hormone concentrations, 17 men were randomly assigned to supplement with 0.3 g/kg per day of creatine monohydrate (CrM: n=9) or placebo (P: n=8) while performing resista...

    journal_title:European journal of applied physiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00421-003-1031-z

    authors: Volek JS,Ratamess NA,Rubin MR,Gómez AL,French DN,McGuigan MM,Scheett TP,Sharman MJ,Häkkinen K,Kraemer WJ

    更新日期:2004-05-01 00:00:00

  • Effects of whole-body vibration and resistance training on knee extensors muscular performance.

    abstract::Whole-body vibration (WBV) is being promoted as an efficient complement to resistance training. The aim of this study was to investigate the effects of an 8-week program of WBV in combination with resistance training on knee extensors muscular performance. A group of 29 young adults (25 men, 4 women; age 21.8 ± 1.5) p...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-011-2091-0

    authors: Artero EG,Espada-Fuentes JC,Argüelles-Cienfuegos J,Román A,Gómez-López PJ,Gutiérrez A

    更新日期:2012-04-01 00:00:00

  • Association between ACE D allele and elite short distance swimming.

    abstract::The influence of ACE gene on athletic performance has been widely explored, and most of the published data refers to an I/D polymorphism leading to the presence (I allele) or absence (D allele) of a 287-bp sequence in intron 16, determining ACE activity in serum and tissues. A higher I allele frequency has been report...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-009-1080-z

    authors: Costa AM,Silva AJ,Garrido ND,Louro H,de Oliveira RJ,Breitenfeld L

    更新日期:2009-08-01 00:00:00

  • Effect of moderate intensity resistance training during weight loss on body composition and physical performance in overweight older adults.

    abstract::The impact of resistance training has not been thoroughly examined in overweight older adults undergoing weight loss. Subjects (n = 27) were overweight and obese (BMI 31.7 +/- 3.6 kg/m(2)) older (age 67 +/- 4 years) adults and were randomized into either a 10-week Dietary Approaches to Stop Hypertension for weight los...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00421-010-1387-9

    authors: Avila JJ,Gutierres JA,Sheehy ME,Lofgren IE,Delmonico MJ

    更新日期:2010-06-01 00:00:00

  • Motor unit recruitment and rate coding in response to fatiguing shoulder abductions and subsequent recovery.

    abstract::The purpose of the present study was to investigate motor unit (MU) recruitment and firing rate, and the MU action potential (MUAP) characteristics of the human supraspinatus muscle during prolonged static contraction and subsequent recovery. Eight female subjects sustained a 30 degrees shoulder abduction, requiring 1...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s004210000278

    authors: Jensen BR,Pilegaard M,Sjøgaard G

    更新日期:2000-10-01 00:00:00

  • Oxygen availability affects exercise capacity, but not neuromuscular fatigue characteristics of knee extensors, during exhaustive intermittent cycling.

    abstract:PURPOSE:To compare the effects of different hypoxia severities on exercise capacity, cardio-respiratory, tissue oxygenation and neuromuscular fatigue characteristics in response to exhaustive intermittent cycling. METHODS:Eleven well-trained cyclists, repeated supra-maximal cycling efforts of 15 s (30% of anaerobic po...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-020-04495-2

    authors: Girard O,Buchheit M,Goodall S,Racinais S

    更新日期:2021-01-01 00:00:00

  • Increased hypoxic ventilatory response during hypovolemic stress imposed through head-up-tilt and lower-body negative pressure.

    abstract::The aim of this study was to quantify the influence of head-up-tilt (HUT) on the isocapnic hypoxic ventilatory response (HVR) in man, and to investigate the effect of orthostatic blood shifts separately from other gravitational effects by the application of lower-body negative pressure (LBNP) with subjects in a horizo...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s004210050070

    authors: Hildebrandt W,Ottenbacher A,Schuster M,Baisch F,Bärtsch P

    更新日期:2000-04-01 00:00:00

  • Muscle architecture and morphology as determinants of explosive strength.

    abstract:PURPOSE:Neural drive and contractile properties are well-defined physiological determinants of explosive strength, the influence of muscle architecture and related morphology on explosive strength is poorly understood. The aim of this study was to examine the relationships between Quadriceps muscle architecture (pennat...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-020-04585-1

    authors: Maden-Wilkinson TM,Balshaw TG,Massey GJ,Folland JP

    更新日期:2021-01-17 00:00:00

  • Human skeletal muscle structure and function preserved by vibration muscle exercise following 55 days of bed rest.

    abstract::Prolonged immobilization of the human body results in functional impairments and musculoskeletal system deconditioning that may be attenuated by adequate muscle exercise. In a 56-day horizontal bed rest campaign involving voluntary males we investigated the effects of vibration muscle exercise (RVE, 2x6 min daily) on ...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00421-006-0160-6

    authors: Blottner D,Salanova M,Püttmann B,Schiffl G,Felsenberg D,Buehring B,Rittweger J

    更新日期:2006-06-01 00:00:00

  • The effects of 3000-m swimming on subsequent 3-h cycling performance: implications for ultraendurance triathletes.

    abstract::The purpose of this study was to examine the physiological effects of 3000-m swimming on subsequent 3-h cycling time trial performance in ultraendurance triathletes. Eight highly trained ultraendurance triathletes [mean (SEM) age 34 (2) years, body fat 12.5 (0.8)%, maximum oxygen consumption 63.2 (2.1) ml x kg(-1) x m...

    journal_title:European journal of applied physiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s004210000229

    authors: Laursen PB,Rhodes EC,Langill RH

    更新日期:2000-09-01 00:00:00

  • Chronic hypobaric hypoxia does not affect electro-mechanical muscle activities during sustained maximal isometric contractions.

    abstract::The aim of the study was to evaluate the influence of chronic hypobaric hypoxia [43 days at 5050 m above sea level, a.s.l.] on the electrical and mechanical activities of the elbow flexor and knee extensor muscles during sustained maximal isometric contractions. Seven subjects participated in this study. The maximal v...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-003-0922-3

    authors: Esposito F,Orizio C,Parrinello G,Veicsteinas A

    更新日期:2003-10-01 00:00:00

  • Effects of neuromuscular fatigue on the electromechanical delay of the leg extensors and flexors in young and old men.

    abstract:PURPOSE:The purpose of this study was to investigate the effects of a fatigue-inducing bout of submaximal, intermittent isometric contractions on the electromechanical delay (EMD) of the leg extensors and flexors in young and old men. METHODS:Twenty young (mean ± SD: age = 25 ± 2.8 years) and sixteen old (age = 70.8 ±...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00421-013-2675-y

    authors: Conchola EC,Thompson BJ,Smith DB

    更新日期:2013-09-01 00:00:00

  • Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway.

    abstract:PURPOSE:Swimming exercise leads to a nonpathological, physiological left ventricular hypertrophy. However, the potential molecular mechanisms are unknown. We investigated the role of microRNAs (miRNA) regulating the cardiac signal cascades were studied in exercised rats. METHODS:Female Wistar rats were assigned into t...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-013-2685-9

    authors: Ma Z,Qi J,Meng S,Wen B,Zhang J

    更新日期:2013-10-01 00:00:00

  • A multiscale model for the simulation of cerebral and extracerebral blood flows and pressures in humans.

    abstract:PURPOSE:Brain hemodynamics is fundamental for the functioning of the human being. Many biophysical factors affect brain circulation, so that a satisfactory understanding of its behavior is challenging. We developed a mathematical model to simulate cerebral and extracerebral flows and pressures in humans. METHODS:The m...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-018-3971-3

    authors: Gadda G,Majka M,Zieliński P,Gambaccini M,Taibi A

    更新日期:2018-11-01 00:00:00

  • K+ potentiates hyperosmolarity-induced vasorelaxations in rat skeletal muscle arterioles.

    abstract::Several regulatory mechanisms have been proposed for the exercise hyperemia in skeletal muscles. Since different vasoactive factors might interact during the hyperemic response, we investigated the influence of elevated K(+) concentrations on hyperosmolarity (HO)-induced vasorelaxations. Small gluteal rat arteries wer...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-005-0128-y

    authors: De Clerck I,Pannier JL,Van de Voorde J

    更新日期:2006-04-01 00:00:00

  • Effect of a personal ambient ventilation system on physiological strain during heat stress wearing a ballistic vest.

    abstract::The present study was conducted in order to evaluate whether physiological strain is alleviated by a new personal cooling system (CS) consisting of a layered vest and integrated blower that generate a flow of air. Twelve male volunteers were exposed to climatic conditions of 40 degrees C, 40%RH (40/40), and 35 degrees...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-008-0716-8

    authors: Hadid A,Yanovich R,Erlich T,Khomenok G,Moran DS

    更新日期:2008-09-01 00:00:00

  • Failure of vascular autoregulation in the upper limb with increased +Gz acceleration.

    abstract::Forearm pain occurring during high +Gz exposure has been linked with vascular distension from elevated transmural pressure of hydrostatic origin and is exacerbated by positive pressure breathing (PBG). We postulated that at high vascular transmural pressure vascular autoregulation might be overcome and be associated w...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-007-0465-0

    authors: Green ND,Brown MD,Coote JH

    更新日期:2007-08-01 00:00:00

  • Alterations of immunoendocrine responses during the recovery period after acute prolonged cycling.

    abstract::The aim of this study was to determine the timecourse of recovery of immunoendocrine responses following prolonged cycling. With the approval of the Ethics Committee, ten healthy men (age 21.6+/-0.9 years, height 1.77+/-0.01 m, body mass 66.9+/-1.8 kg, VO2max 54.2+/-2.0 ml kg(-1) min(-1); means+/-SEM) performed either...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-007-0529-1

    authors: Li TL,Cheng PY

    更新日期:2007-11-01 00:00:00

  • Effect of intermittent hypoxic training on HIF gene expression in human skeletal muscle and leukocytes.

    abstract::Intermittent hypoxic exposure with exercise training is based on the assumption that brief exposure to hypoxia is sufficient to induce beneficial muscular adaptations mediated via hypoxia-inducible transcription factors (HIF). We previously demonstrated (Mounier et al. Med Sci Sports Exerc 38:1410-1417, 2006) that leu...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-008-0928-y

    authors: Mounier R,Pialoux V,Roels B,Thomas C,Millet G,Mercier J,Coudert J,Fellmann N,Clottes E

    更新日期:2009-03-01 00:00:00

  • Respiration-related cerebral blood flow variability increases during control-mode non-invasive ventilation in normovolemia and hypovolemia.

    abstract:PURPOSE:Increased variability in cerebral blood flow (CBF) predisposes to adverse cerebrovascular events. Oscillations in arterial blood pressure and PaCO2 induce CBF variability. Less is known about how heart rate (HR) variability affects CBF. We experimentally reduced respiration-induced HR variability in healthy sub...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-017-3711-0

    authors: Skytioti M,Søvik S,Elstad M

    更新日期:2017-11-01 00:00:00

  • Frowning muscle activity and perception of effort during constant-workload cycling.

    abstract::We have recently demonstrated that electromyogram (EMG) amplitude of the frowning muscles correlates with perception of effort during leg-extension exercise. However, during aerobic exercise the relationship between facial EMG and perception of effort has never been investigated. The aim of the present study was to in...

    journal_title:European journal of applied physiology

    pub_type: 杂志文章

    doi:10.1007/s00421-011-2138-2

    authors: de Morree HM,Marcora SM

    更新日期:2012-05-01 00:00:00