A systematic review and meta-analysis including GRADE qualification of the risk of surgical site infections after prophylactic negative pressure wound therapy compared with conventional dressings in clean and contaminated surgery.

Abstract:

OBJECTIVE:Systematically review and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) studies on prophylactic negative pressure wound therapy (pNPWT) to prevent surgical site infections (SSIs). INTRODUCTION:pNPWT has been suggested as a new method to prevent wound complications, specifically SSIs, by its application on closed incisional wounds. METHODS:This review was conducted as part of the development of the Global Guidelines for prevention of SSIs commissioned by World Health Organization in Geneva. PubMed, Embase, CENTRAL, CINAHL, and the World Health Organization database between January 1, 1990 and October 7, 2015 were searched. Inclusion criteria were randomized controlled trials and observational studies comparing pNPWT with conventional wound dressings and reporting on the incidence of SSI. Meta-analyses were performed with a random effect model. GRADE Pro software was used to qualify the evidence. RESULTS:Nineteen articles describing 21 studies (6 randomized controlled trials and 15 observational) were included in the review. Summary estimate showed a significant benefit of pNPWT over conventional wound dressings in reducing SSIs in both randomized controlled trials and observational studies, odds ratio of 0.56 (95% confidence interval, 0.32-0.96; P = 0.04) and odds ratio of 0.30 (95% confidence interval, 0.22-0.42; P < 0.00001), respectively. This translates into lowering the SSI rate from 140 to 83 (49-135) per 1000 patients and from 106 to 34 (25-47) per 1000 patients, respectively. In stratified analyses, these results were consistent in both clean and clean-contaminated procedures and in different types of surgery, however results were no longer significant for orthopaedic/trauma surgery. The level of evidence as qualified with GRADE was however low. CONCLUSIONS:Low-quality evidence indicates that prophylactic NPWT significantly reduces the risk of SSIs.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

De Vries FEE,Wallert ED,Solomkin JS,Allegranzi B,Egger M,Dellinger EP,Boermeester MA

doi

10.1097/MD.0000000000004673

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

e4673

issue

36

eissn

0025-7974

issn

1536-5964

pii

00005792-201609060-00029

journal_volume

95

pub_type

杂志文章,meta分析,评审

相关文献

MEDICINE文献大全
  • Clinical significance of increased cerebellar default-mode network connectivity in resting-state patients with drug-naive somatization disorder.

    abstract::The cerebellum has been proven to be connected to the brain network, as in the default-mode network (DMN), among healthy subjects and patients with psychiatric disorders. However, whether or not abnormal cerebellar DMN connectivity exists and what its clinical significance is among drug-naive patients with somatizatio...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004043

    authors: Wang H,Guo W,Liu F,Chen J,Wu R,Zhang Z,Yu M,Li L,Zhao J

    更新日期:2016-07-01 00:00:00

  • Surgical management of delayed Gartland type III supracondylar humeral fractures in children: A retrospective comparison of radial external fixator and crossed pinning.

    abstract::Radial external fixator has been proposed to treat delayed irreducible Gartland type III supracondylar humeral fracture, and this study aims to compare its effects with crossed pinning in a retrospective fashion. Delayed supracondylar humeral fracture is defined as more than 72 hours after injury, 2 or more than 2 tim...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019449

    authors: Li J,Rai S,Tang X,Ze R,Liu R,Hong P

    更新日期:2020-03-01 00:00:00

  • Case report: A non-obstructive azoospermia patient with heat shock factor-2 mutation.

    abstract:RATIONALE:Infertility is a common medical condition that affects nearly 15% of the world population. Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Some common structural variants, single nucleotide polymorphisms (SNPs), and genetic factors were reported to be associated with NOA...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021107

    authors: Zhao H,Zhang H,Xi Q,Li L,Zhu H,Hu X,Liu R

    更新日期:2020-07-31 00:00:00

  • Inflammatory demyelinating neuropathies with focal segmental glomerulosclerosis: Two case reports.

    abstract:RATIONALE:Inflammatory demyelinating neuropathies such as Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and focal segmental glomerulosclerosis (FSGS) are autoimmune disorders that may have a common pathogenesis. Here, we describe 2 unique cases of FSGS, 1 with GBS and the othe...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013304

    authors: Mao Y,Zhang M,Liu S,Xu Y,Xue J,Hao C,Lai L

    更新日期:2018-12-01 00:00:00

  • An unusual location of gouty panniculitis: A case report.

    abstract:RATIONALE:Gouty panniculitis, characterised by the deposition of monosodium urate crystals in subcutaneous tissue, is a rare clinical manifestation of gout. PATIENT CONCERNS:The case of a 67-year-old man is reported, who presented an erythematous nodule on the upper part of the right buttock suspicious for an abscess....

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006733

    authors: Martin D,Joliat GR,Fournier P,Brunel C,Demartines N,Gié O

    更新日期:2017-04-01 00:00:00

  • Oral oxymatrine for hepatitis B cirrhosis: A systematic review protocol.

    abstract:BACKGROUND:Characterized by diffuse hepatic fibrosis and nodule formation, hepatitis B cirrhosis (HBC), an important result of chronic hepatitis B development, mainly contains compensated and decompensated stage. Compensated cirrhosis can further develop into decompensated stage and hepatocellular carcinoma with seriou...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000013482

    authors: Jiang X,Xie L,Huang C,Liu Y,Liu H,Liu B,Zheng L

    更新日期:2018-12-01 00:00:00

  • Lower circulating angiotensin II levels are related to the severity of preeclampsia and its risk as disclosed by a specific bioassay.

    abstract::Preeclampsia is characterized by an increased sensitivity to angiotensin II (Ang II). We herein assessed whether serum Ang II levels measured by a new developed bioassay are associated with preeclampsia, its severity, and the risk for developing this disease.Using a cross-sectional design, we studied 90 pregnant women...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012498

    authors: Leaños-Miranda A,Inova Campos-Galicia,Méndez-Aguilar F,Molina-Pérez CJ,Ramírez-Valenzuela KL,Sillas-Pardo LJ,Uraga-Camacho NC,Isordia-Salas I,Berumen-Lechuga MG

    更新日期:2018-09-01 00:00:00

  • Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

    abstract::Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007572

    authors: Martín Lorenzo T,Albi Rodríguez G,Rocon E,Martínez Caballero I,Lerma Lara S

    更新日期:2017-07-01 00:00:00

  • Evaluation of umbilical anatomy via computed tomography prior to single-incision laparoscopy.

    abstract::Laparoscopic surgery performed through a single incision is relatively new. Here, we investigated the importance of radiological anatomical evaluation of the umbilicus prior to such surgery.Umbilical images of 500 patients who underwent computed tomography (CT) in 2019 were evaluated retrospectively, using both transv...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021252

    authors: Oztop MB,Er A

    更新日期:2020-07-10 00:00:00

  • A novel index including SNPs for the screening of nonalcoholic fatty liver disease among elder Chinese: A population-based study.

    abstract::Presently noninvasive methods were employed to the diagnosis of nonalcoholic fatty liver disease (NAFLD), including fatty liver index (FLI), hepatic steatosis index (HSI), product of fasting triglyceride and glucose levels (TyG), and single nucleotide polymorphism (SNP), whereas the accuracy of those indexes need to b...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010272

    authors: Yang H,Chen G,Song C,Li D,Ma Q,Chen G,Li X

    更新日期:2018-03-01 00:00:00

  • Implementation effectiveness of revised (post-2010) World Health Organization guidelines on prevention of mother-to-child transmission of HIV using routinely collected data in sub-Saharan Africa: A systematic literature review.

    abstract:BACKGROUND:To synthesize and evaluate the impact of implementing post-2010 World Health Organization (WHO) prevention of mother-to-child transmission (PMTCT) guidelines on attainment of PMTCT targets. METHODS:Retrospective and prospective cohort study designs that utilized routinely collected data with a focus on prov...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000008055

    authors: Gumede-Moyo S,Filteau S,Munthali T,Todd J,Musonda P

    更新日期:2017-10-01 00:00:00

  • Medical Comics as Tools to Aid in Obtaining Informed Consent for Stroke Care.

    abstract::Informed consent has now become common in medical practice. However, a gap still exists between doctors and patients in the understanding of clinical conditions. We designed medical comics about "subarachnoid hemorrhage" and "intracerebral hemorrhage" to help doctors obtain informed consent intuitively, quickly, and c...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001077

    authors: Furuno Y,Sasajima H

    更新日期:2015-07-01 00:00:00

  • Unusual recurrent renal secondary hyperparathyroidism caused by hyperplastic autograft with supernumerary parathyroid adenoma: A case report.

    abstract:RATIONALE:Secondary hyperparathyroidism (SHPT) is often complicated with chronic renal failure. Though the total parathyroidectomy (TPTX) with forearm autotransplantation (FAT) has been commonly used to treatment refractory renal SHPT, the recurrence of SHPT is not infrequent, resulting from hyperplastic autograft, rem...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016077

    authors: Zhang J,Dong MJ,Yang J,Tian D

    更新日期:2019-06-01 00:00:00

  • Primary Squamous Cell Carcinoma of Liver: Case Series and Review of Literatures.

    abstract::Primary squamous cell carcinoma (SCC) of liver is rare, and its prognosis is extremely poor. This study aims at reviewing the clinical data of all pathologically diagnosed liver cancer in our institute, and discussing the clinical presentation, diagnosis, treatment, and prognosis of our cases of SCC and the literature...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000000868

    authors: Zhang XF,Du ZQ,Liu XM,Lv Y

    更新日期:2015-07-01 00:00:00

  • Impact of atrial arrhythmias after esophagectomy on recovery: A meta-analysis.

    abstract:BACKGROUND:Postoperative atrial arrhythmias (PAAs) are common complications after esophagectomy, however research findings are contradicted on the prognosis. Therefore this meta-analysis was conducted to determine whether PAAs after esophagectomy had an impact on prognosis. METHODS:Studies comparing prognosis between ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000010948

    authors: Chen LT,Jiang CY

    更新日期:2018-06-01 00:00:00

  • Metastatic epithelioid trophoblastic tumor of the lung: A case report.

    abstract:RATIONALE:Epithelioid trophoblastic tumor (ETT) is a very rare form of gestational trophoblastic disease (GTD) which arises from neoplastic proliferation of intermediate trophoblasts. Metastatic ETT of the lung is extremely rare in postmenopausal women. PATIENT CONCERNS:Here we describe a 50-year-old woman with a meta...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010306

    authors: Lei W,Zhang F,Zheng C,Zhao C,Tu S,Bao Y

    更新日期:2018-04-01 00:00:00

  • A cross-sectional observational study of pneumococcal carriage in children, their parents, and older adults following the introduction of the 7-valent pneumococcal conjugate vaccine.

    abstract::Using nasopharyngeal carriage as a marker of vaccine impact, pneumococcal colonization and its relation to invasive disease were examined in children, their parents, and older adults in the United Kingdom following introduction of 7-valent pneumococcal conjugate vaccine (PCV7) and prior to 13-valent pneumococcal conju...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000335

    authors: Hamaluba M,Kandasamy R,Ndimah S,Morton R,Caccamo M,Robinson H,Kelly S,Field A,Norman L,Plested E,Thompson BAV,Zafar A,Kerridge SA,Lazarus R,John T,Holmes J,Fenlon SN,Gould KA,Waight P,Hinds J,Crook D,Snape MD,

    更新日期:2015-01-01 00:00:00

  • Challenges in the diagnosis of Boerhaave syndrome: A case report.

    abstract:RATIONALE:Acute chest pain remains one of the most challenging complaints of patients presenting to emergency departments (EDs). The diverse etiologies of chest pain frequently lead to diagnostic and therapeutic challenges. Esophageal perforation is a rare but potentially life-threatening disease. It results in delayed...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018765

    authors: Tzeng CH,Chen WK,Lu HC,Chen HH,Lee KI,Wu YS,Lee FY

    更新日期:2020-01-01 00:00:00

  • Effectiveness and safety of Danshen injection on heart failure: Protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:Danshen injection (DSI) is a traditional Chinese medicine preparation extracted from Danshen (Salvia miltiorrhiza), which has the functions of promoting blood circulation and removing blood stasis. Heart failure (HF) is a complex cardiovascular disease, always leading to frequent onset and hospitalization, d...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015636

    authors: Yuan T,Chen Y,Zhou X,Lin X,Zhang Q

    更新日期:2019-05-01 00:00:00

  • Treatment of a Simple Bone Cyst Using a Cannulated Hydroxyapatite Pin.

    abstract::Simple bone cysts (SBCs) are benign bone tumors. However, the treatment of SBCs remains controversial because of their healing rate and the invasiveness of surgery. The purpose of the present study was to evaluate the treatment of SBCs using a cannulated hydroxyapatite (HA) pin.A total of 43 patients (35 males, 8 fema...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001027

    authors: Shirai T,Tsuchiya H,Terauchi R,Tsuchida S,Mizoshiri N,Ikoma K,Fujiwara H,Miwa S,Kimura H,Takeuchi A,Hayashi K,Yamamoto N,Kubo T

    更新日期:2015-06-01 00:00:00

  • Clinical Immunophenotype at Disease Onset in Previously Healthy Patients With Cryptococcal Meningitis.

    abstract::Cryptococcal meningitis (CM) is a global disease with significant morbidity and mortality. Although low peripheral blood cluster of differentiation 4 (CD4) cell counts are found to be related to a high burden of cryptococcus in HIV-infected patients, little is known about possible immune defects in previously healthy ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002744

    authors: Xu L,Huang Q,Lin JR,Zhu CY,Li XH,Ye SK,Zhu AH,Chen DH,Zhang CF,Chen L,Ling Y

    更新日期:2016-02-01 00:00:00

  • Cutaneous metastasis of ascending colon cancer harboring a BRAF V600E mutation: A rare case report.

    abstract:RATIONALE:Cutaneous metastases from colorectal cancer are extremely rare and generally appear several years after diagnosis or resection of the primary colorectal tumor. Although cutaneous metastasis is unusual, it often indicates a poor prognosis. PATIENT CONCERNS:We treated a 62-year-old woman with multiple cutaneou...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020026

    authors: Liao L,Cheng Q,Zhu G,Pei F,Ye S

    更新日期:2020-05-22 00:00:00

  • The association between normal-range admission potassium levels in Israeli patients with acute coronary syndrome and early and late outcomes.

    abstract::Abnormal serum potassium levels are associated with an increased risk of ventricular arrhythmias and mortality in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate whether different levels of serum potassium, within the normal range, are associated with worse outcomes. The p...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000003778

    authors: Shlomai G,Berkovitch A,Pinchevski-Kadir S,Bornstein G,Leibowitz A,Goldenberg I,Grossman E

    更新日期:2016-06-01 00:00:00

  • Survival and restoration of pulmonary perfusion in a long-term follow-up of patients after acute pulmonary embolism.

    abstract::We followed prospectively 834 consecutive patients (70% inpatients), evaluated for suspected pulmonary embolism, for a median time of 2.1 years (range, 0-4.8 yr), and compared the survival rates in patients with proven pulmonary embolism (n=320) with those without (n=514). In multivariate analysis, we modeled the prob...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/01.md.0000236952.87590.c8

    authors: Miniati M,Monti S,Bottai M,Scoscia E,Bauleo C,Tonelli L,Dainelli A,Giuntini C

    更新日期:2006-09-01 00:00:00

  • Combined effect of laser acupuncture and electroacupuncture in knee osteoarthritis patients: A protocol for a randomized controlled trial.

    abstract:BACKGROUND:Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. The most common treatment for KOA is non-steroidal anti-inflammatory drug administra...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000019541

    authors: Wu SY,Lin CH,Chang NJ,Hu WL,Hung YC,Tsao Y,Kuo CA

    更新日期:2020-03-01 00:00:00

  • Ultrasound-guided high-intensity focused ultrasound in the treatment of uterine fibroids.

    abstract::The aim of the present study was to investigate factors affecting ablation effect and safety of ultrasound-guided high-intensity focused ultrasound (USgHIFU) for uterine fibroids (UFs).A retrospective analysis of 346 patients with symptomatic UFs who were treated with USgHIFU was performed. All UFs was grouped based o...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014566

    authors: Fan HJ,Zhang C,Lei HT,Cun JP,Zhao W,Huang JQ,Zhai Y

    更新日期:2019-03-01 00:00:00

  • Correlation of left atrial wall thickness and atrial remodeling in atrial fibrillation: Study based on low-dose-ibutilide-facilitated catheter ablation.

    abstract::Atrial remodeling plays a significant role during the progression of atrial fibrillation (AF). Left atrial wall thickness (LAT) is a subjective and easily acquirable indicator referring to structural remodeling. Therefore, we aimed to investigate the association between LAT and atrial remodeling substrate, and to expl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015170

    authors: Zuo K,Li K,Liu M,Li J,Liu X,Liu X,Zhong J,Yang X

    更新日期:2019-04-01 00:00:00

  • Evaluation of multiple screening methods for cervical cancers in rural areas of Xinjiang, China.

    abstract::This study is to evaluate the screening methods of cervical cancers for rural females in Kash bachu, Xinjiang, China.A total number of 3000 married females were surveyed, and subjected to the gynecological examination. In these subjects, 1993 females received the careHPV (human papillomavirus) test, while 1007 females...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019135

    authors: Naizhaer G,Yuan J,Mijiti P,Aierken K,Abulizi G,Qiao Y

    更新日期:2020-02-01 00:00:00

  • Relationship between ultrasonographic and pathologic calcification patterns in papillary thyroid cancer.

    abstract::Ultrasonographic microcalcification is highly related to papillary thyroid cancer (PTC) and pathologic psammoma body is a poor prognostic factor. However, it is little known about whether the microcalcifications seen on ultrasonography are consistent with the pathologic psammoma bodies. We evaluated the relationship b...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012675

    authors: Kim BK,Lee EM,Kim JH,Oak SY,Kwon SK,Choi YS,Kim YO

    更新日期:2018-10-01 00:00:00

  • Gender-based impact of epidermal growth factor receptor mutation in patients with nonsmall cell lung cancer and previous tuberculosis.

    abstract::The association between tuberculosis (TB) and lung cancer is well known. However, carcinogenesis of TB and its connection with epidermal growth factor receptor (EGFR) mutation remains unclear. This study aimed to determine this connection to see if TB can affect the outcome of patients with lung cancer. This is a retr...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000444

    authors: Chang CH,Lee CH,Ho CC,Wang JY,Yu CJ

    更新日期:2015-01-01 00:00:00