Bursts of Chromosome Changes Drive TNBC.

Abstract:

:A recent study suggests that complex genomic rearrangements in triple-negative breast cancer cells occur through a "Big Bang" model-early, short bursts of copy number aberrations, rather than progressive accumulation over time. Afterward, these aberrations are stably maintained in a handful of clones that expand to form the tumor mass.

journal_name

Cancer Discov

journal_title

Cancer discovery

authors

doi

10.1158/2159-8290.CD-NB2016-110

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

1075

issue

10

eissn

2159-8274

issn

2159-8290

pii

2159-8290.CD-NB2016-110

journal_volume

6

pub_type

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